Overview
Background
Dr Pingping Han is currently leading the Epigenetic Nanodiagnostics and Therapeutics Group within the Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3), at the UQ School of Dentistry. Dr Han received her PhD in Biomedical Engineering from the Queensland University of Technology (QUT) in 2014. Dr Han's current research focuses on three themes: a) salivary diagnostics for periodontal disease, b) “cell-free” regenerative therapy for periodontal tissue engineering and c) cellular nano-mechanics on different modified biomaterial substrates.
Availability
- Dr Pingping Han is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Queensland University of Technology
Research interests
-
Cell-free therapy for periodontal regeneration
-
Saliva diagnosis
-
Epigenetic diagnosis and therapy
-
Periodontal diagnosis and therapy
Works
Search Professor Pingping Han’s works on UQ eSpace
2026
Journal Article
Biological responses to biomaterials: mechanisms and opportunities for enhanced oral tissue regeneration
Zhou, Yinghong, Xu, Tian, Han, Pingping, Wang, Cong, Bartold, Mark and Ivanovski, Sašo (2026). Biological responses to biomaterials: mechanisms and opportunities for enhanced oral tissue regeneration. Journal of Periodontal Research jre.70078. doi: 10.1111/jre.70078
2026
Journal Article
Effect of periodontal therapy on salivary extracellular vesicle cargos: an exploratory study
Wang, Jenny, Liu, Chun, Lai, Andrew, Salomon, Carlos, Lee, Ryan S. B., Ivanovski, Sašo and Han, Pingping (2026). Effect of periodontal therapy on salivary extracellular vesicle cargos: an exploratory study. Journal of Clinical Periodontology, 53 (2), 232-243. doi: 10.1111/jcpe.70051
2026
Journal Article
Circulating extracellular vesicle DNA (EV-DNA) and cell-free DNA in ovarian cancer: pathological relevance and diagnostic applications
Guanzon, Dominic, Sankar, Rakesh, Lodha, Pragati, Purushothaman, Reshinthine, Huang, Shiyuan, Jayabalan, Nanthini, Dahanayake, Madushani, Ahmed, Emtiaz, Han, Pingping, Masud, Mostafa Kamal, Yamauchi, Yusuke and Salomon, Carlos (2026). Circulating extracellular vesicle DNA (EV-DNA) and cell-free DNA in ovarian cancer: pathological relevance and diagnostic applications. Extracellular Vesicles and Circulating Nucleic Acids, 7 (1), 114-145. doi: 10.20517/evcna.2025.120
2026
Journal Article
Extracellular vesicles in gingival crevicular fluid as indicators of periodontitis and early response to non-surgical periodontal therapy
Han, Pingping, Liaw, Andrew, Vithanage, Akila Suboda, Salomon, Carlos and Ivanovski, Sašo (2026). Extracellular vesicles in gingival crevicular fluid as indicators of periodontitis and early response to non-surgical periodontal therapy. Journal of Periodontal Research jre.70070. doi: 10.1111/jre.70070
2026
Journal Article
Nano-engineered titanium implants loaded with gingival fibroblasts-derived microvesicles enhance early osseointegration and soft tissue attachment in vivo
Han, Pingping, Liu, Chun, Jayasree, Anjana, Sokolowski, Kamil, Liaw, Andrew, Liu, Dingbin, Salomon, Carlos, Gulati, Karan, Lee, Ryan S. B., Huang, Baoxin and Ivanovski, Sašo (2026). Nano-engineered titanium implants loaded with gingival fibroblasts-derived microvesicles enhance early osseointegration and soft tissue attachment in vivo. Advanced Healthcare Materials e04516, e04516. doi: 10.1002/adhm.202504516
2026
Journal Article
Salivary large extracellular vesicle associated bacterial DNA reflects periodontal disease status and non-surgical periodontal therapy response
Ning, Yang, Ramachandra, Srinivas Sulugodu, Bennett, Nigel, Ivanovski, Sašo and Han, Pingping (2026). Salivary large extracellular vesicle associated bacterial DNA reflects periodontal disease status and non-surgical periodontal therapy response. Dental Research, 1 (1) 100006, 1-11. doi: 10.1016/j.dtrs.2025.100006
2026
Journal Article
An “anaerobic invisible” genetically engineered bacterium for periodontitis treatment through temporal modulation on microenvironment
Sun, Jiwei, Zhang, Junshuai, Lei, Haoqi, Tang, Qingming, Han, Pingping, Xia, Yutian, Deng, Ronghua, Wang, Yifan, Shi, Yunsong, Zhang, Junyuan, Zhang, Yifan, Han, Zhenshuo, Huang, Yingjia, Wu, Yuzhou and Chen, Lili (2026). An “anaerobic invisible” genetically engineered bacterium for periodontitis treatment through temporal modulation on microenvironment. Dental Research, 1 (1) 100002, 100002. doi: 10.1016/j.dtrs.2025.100002
2025
Journal Article
Synergistic potentials of small extracellular vesicles, biomaterials, and 3D bioprinting in periodontal regeneration: a scoping review
Zhang, Chenyi, Liu, Chun, Liaw, Andrew, Ivanovski, Sašo and Han, Pingping (2025). Synergistic potentials of small extracellular vesicles, biomaterials, and 3D bioprinting in periodontal regeneration: a scoping review. Extracellular Vesicles and Circulating Nucleic Acids, 6 (4), 954-981. doi: 10.20517/evcna.2025.107
2025
Journal Article
Bioengineered mPCL scaffolds with LiCl-stimulated hPDLCs cell sheets for enhanced periodontal regeneration
Han, Pingping, Dan, Hongxia, Vaquette, Cedryck, Liaw, Andrew, Zhou, Yinghong and Ivanovski, Sašo (2025). Bioengineered mPCL scaffolds with LiCl-stimulated hPDLCs cell sheets for enhanced periodontal regeneration. Clinical Oral Investigations, 29 (12) 587, 1-15. doi: 10.1007/s00784-025-06667-w
2025
Journal Article
A survey of Australian consumers' and dentists’ perceptions of saliva as a biofluid for periodontitis diagnosis
Sun, Ruiyi, Amidi, Sarina, Yee, Jia Ying, Liaw, Andrew, Hosseinpour, Sepanta, Ivanovski, Sašo, Kocak Oztug, Necla Asli and Han, Pingping (2025). A survey of Australian consumers' and dentists’ perceptions of saliva as a biofluid for periodontitis diagnosis. BMC Oral Health, 25 (1) 1672, 1672. doi: 10.1186/s12903-025-07062-3
2025
Journal Article
Association Between Salivary Circular RNAs Expression and Periodontal Disease Status
Han, Pingping, Jiao, Kexin, Bartold, Peter Mark, Liaw, Andrew, Wei, Wei and Ivanovski, Sašo (2025). Association Between Salivary Circular RNAs Expression and Periodontal Disease Status. Journal of Periodontal Research, 60 (10), 1053-1055. doi: 10.1111/jre.70004
2025
Journal Article
Proteome and microbiome profiles of polymicrobial salivary biofilms on 3D MEW fibrous scaffolds: biomimetic ECM-inspired structures
Han, Pingping, Liu, Chun, Abdal-Hay, Abdala, Reed, Sarah, Liaw, Andrew, Wang, Jenny, Ning, Yang and Ivanovski, Sašo (2025). Proteome and microbiome profiles of polymicrobial salivary biofilms on 3D MEW fibrous scaffolds: biomimetic ECM-inspired structures. Journal of Materials Chemistry B, 13 (41), 13434-13445. doi: 10.1039/d5tb01410g
2025
Journal Article
Short-term probiotic colonization alters molecular dynamics of 3D oral biofilms
Udawatte, Nadeeka S., Liu, Chun, Staples, Reuben, Han, Pingping, Kumar, Purnima S., Arumugam, Thiruma V., Ivanovski, Sašo and Seneviratne, Chaminda J. (2025). Short-term probiotic colonization alters molecular dynamics of 3D oral biofilms. International Journal of Molecular Sciences, 26 (13) 6403, 6403-13. doi: 10.3390/ijms26136403
2025
Journal Article
Enhanced yield and proteomic profile of osteoblast-derived extracellular vesicles from 3D MEW mPCL scaffolds
Liu, Chun, Zhang, Chenyi, Hua, Shu, Salomon, Carlos, Ivanovski, Sašo and Han, Pingping (2025). Enhanced yield and proteomic profile of osteoblast-derived extracellular vesicles from 3D MEW mPCL scaffolds. Journal of Materials Chemistry B, 13 (26), 7785-7796. doi: 10.1039/d5tb00021a
2025
Journal Article
Systemic Azithromycin as an Adjunct to Non-Surgical Subgingival Instrumentation in the Treatment of Stage III/IV, Grade C Periodontitis: 12-Month Clinical, Microbiological and Cytokine Results of a Randomised Controlled Trial
Sulugodu Ramachandra, Srinivas, Woodford, Valerie, Han, Pingping, Lee, Ryan S. B. and Ivanovski, Sašo (2025). Systemic Azithromycin as an Adjunct to Non-Surgical Subgingival Instrumentation in the Treatment of Stage III/IV, Grade C Periodontitis: 12-Month Clinical, Microbiological and Cytokine Results of a Randomised Controlled Trial. Journal of Clinical Periodontology, 52 (5), 1-15. doi: 10.1111/jcpe.14150
2025
Journal Article
Microbial DNA profiles of bacterial extracellular vesicles from 3D salivary polymicrobial biofilms - a pilot study
Liu, Chun, Udawatte, Nadeeka S., Liaw, Andrew, Staples, Reuben, Salomon, Carlos, Seneviratne, Chaminda Jayampath, Ivanovski, Sašo and Han, Pingping (2025). Microbial DNA profiles of bacterial extracellular vesicles from 3D salivary polymicrobial biofilms - a pilot study. Advanced Healthcare Materials, 14 (6) e2403300, e2403300. doi: 10.1002/adhm.202403300
2024
Journal Article
The therapeutic use of dental mesenchymal stem cells in human clinical trials
Ivanovski, S., Han, P., Peters, O. A., Sanz, M. and Bartold, P. M. (2024). The therapeutic use of dental mesenchymal stem cells in human clinical trials. Journal of Dental Research, 103 (12), 220345241261900-1184. doi: 10.1177/00220345241261900
2024
Journal Article
Fabrication of 3D Bioactive Melt Electrowriting Composite Scaffold with High Osteogenic Potential
Abdal-hay, Abdalla, Kocak-Oztug, Necla Asli, Sheikh, Faheem A., Han, Pingping, Anwar, Saqib, Fournier, Benjamin P.J. and Ivanovski, Sašo (2024). Fabrication of 3D Bioactive Melt Electrowriting Composite Scaffold with High Osteogenic Potential. Colloids and Surfaces B: Biointerfaces, 245 114270, 1-13. doi: 10.1016/j.colsurfb.2024.114270
2024
Journal Article
Effect of non-surgical periodontal therapy on salivary histone deacetylases expression: a prospective clinical study
Liaw, Andrew, Liu, Chun, Bartold, Mark, Ivanovski, Sašo and Han, Pingping (2024). Effect of non-surgical periodontal therapy on salivary histone deacetylases expression: a prospective clinical study. Journal of Clinical Periodontology, 51 (7), 926-935. doi: 10.1111/jcpe.13973
2024
Journal Article
Microbial- and host immune cell-derived extracellular vesicles in the pathogenesis and therapy of periodontitis: a narrative review
Wang, Jenny, Liu, Chun, Cutler, Jason, Ivanovski, Sašo, Lee, Ryan S. B. and Han, Pingping (2024). Microbial- and host immune cell-derived extracellular vesicles in the pathogenesis and therapy of periodontitis: a narrative review. Journal of Periodontal Research, 59 (6), 1115-1129. doi: 10.1111/jre.13283
Funding
Current funding
Supervision
Availability
- Dr Pingping Han is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
-
Periodontal cell derived extracellular vesicles as treatment for periodontitis
Investigating the potential of periodontal cell-derived extracellular vesicles (EVs) as a 'cell-free' therapy for a chronic oral disease - periodontitis.
-
Nano-diagnostics for periodontal disease
-
Cellular nano-mechanics on different biomaterial surfaces
-
Omics and epigenetics in dentistry
Supervision history
Current supervision
-
Doctor Philosophy
Stem cell derived exosomes for periodontal regeneration
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
Master Philosophy
Proteomic profiles for healthy salivary biofilm grown on 2D TCP and 3D mPCL scaffolds
Principal Advisor
Other advisors: Professor Saso Ivanovski, Associate Professor Jaya Seneviratne
-
Doctor Philosophy
The emerging role of microbial extracellular vesicles in periodontitis
Principal Advisor
Other advisors: Professor Saso Ivanovski, Associate Professor Jaya Seneviratne
-
Doctor Philosophy
Fabrication and Characterisation of Polyamide-12 As Occlusal Device Material For Bruxism Management
Associate Advisor
Other advisors: Professor Saso Ivanovski
-
Doctor Philosophy
Treg-derived small extracellular vesicles reprogram local immune responses for enhanced periodontal regeneration.
Associate Advisor
Other advisors: Professor Saso Ivanovski, Dr Yinghong Zhou
-
Doctor Philosophy
Biomarkers for peri- implantitis diagnosis and treatment monitoring
Associate Advisor
Other advisors: Professor Saso Ivanovski
-
Doctor Philosophy
3D bioprinting of an Oral mucosal model
Associate Advisor
Other advisors: Dr Reuben Staples, Professor Saso Ivanovski
-
Doctor Philosophy
Periodontal pathogenic bacterial enzymes as a potential diagnostic marker for the development of Rheumatoid Arthritis.
Associate Advisor
Other advisors: Professor Saso Ivanovski, Associate Professor Ryan Lee
Completed supervision
-
2024
Master Philosophy
The osteogenic capability of 3D bioprinted osteoblast-derived extracellular vesicles
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
2025
Doctor Philosophy
Optimizing Implant Nano-Texturing Towards Bioactivity and Antibacterial Functions
Associate Advisor
Other advisors: Professor Saso Ivanovski
-
2023
Doctor Philosophy
Fabrication Optimization of Bioactive Nano-Engineered Titanium Dental Implants
Associate Advisor
Other advisors: Professor Saso Ivanovski, Dr Karan Gulati
-
2022
Doctor Philosophy
Effect of azithromycin on oral biofilms and as an adjunct to the non-surgical treatment of periodontitis.
Associate Advisor
Other advisors: Associate Professor Ryan Lee, Professor Saso Ivanovski
Media
Enquiries
Contact Dr Pingping Han directly for media enquiries about:
- extracellular vesicles
- Periodontal regeneration
- periodontitis
- saliva diagnosis
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: