Overview
Background
Dr Karan Gulati is a Research Group Leader and the Deputy Director of Research at the School of Dentistry, UQ. He is also the Deputy Director of Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3) at UQ Dentistry.
Dr Gulati is a pioneer in electrochemically nano-engineered dental implants with over 13 years of extensive research experience using nano-engineering towards various bioactive and therapeutic applications. Dr Gulati completed his PhD from the University of Adelaide (Australia) in 2015 and was awarded the Dean’s Commendation for Doctoral Thesis Excellence. His career has been supported by prestigious fellowships from NHMRC (National Health and Medical Research Council, Australia), JSPS (Japan Society for the Promotion of Science, Japan), Erasmus+ (Germany) and the University of Queensland. At 8 years post-PhD, Dr Gulati has edited 3 books, published 7 chapters and >72 publications (h-index 35), and presented >110 times in various reputed conferences.
Availability
- Dr Karan Gulati is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Adelaide
Research impacts
The trans-mucosal nature of dental implants presents a unique challenge from a biomaterial perspective, requiring rapid establishment and maintenance of osseointegration in the alveolar bone of varying quantity and quality and the formation of resilient, soft tissue integration. Key challenges in achieving long-term dental implant success include sub-optimal osseointegration, soft-tissue integration, immunomodulation and onset of bacterial infection.
Dental implant surfaces have been enhanced via mechanical, chemical, and biological modifications to manage the complex therapeutic requirements of the dental microenvironment. Among these, nanotubes (NTs) or nanopores (NPs) engineered on implant surfaces (Ti, Zr, NiTi, Ti64 alloys, dental/orthopaedic/craniofacial implants) using electrochemical anodisation present considerable therapeutic potential due to several favourable properties, including enhanced integration, tailorable drug loading/release and mechano-transduction.
Dr. Gulati’s research group GATORs (Group for Anodized Therapies for Osseointegration, Regeneration and Stimulation) focus on the developments and challenges associated with nano-engineered implants, focusing on generating tailorable devices that can address the unique challenges related to biomedical implants.
Works
Search Professor Karan Gulati’s works on UQ eSpace
2024
Journal Article
Inflammatory or Reparative? Tuning Macrophage Polarization Using Anodized Anisotropic Nanoporous Titanium Implant Surfaces
Moon, Ho‐Jin, Gulati, Karan, Li, Tao, Moran, Corey Stephen and Ivanovski, Sašo (2024). Inflammatory or Reparative? Tuning Macrophage Polarization Using Anodized Anisotropic Nanoporous Titanium Implant Surfaces. Small Science. doi: 10.1002/smsc.202400211
2024
Journal Article
Bioinspired, bioactive, and bactericidal: anodized nanotextured dental implants
Chopra, Divya, Guo, Tianqi, Jayasree, Anjana, Gulati, Karan and Ivanovski, Sašo (2024). Bioinspired, bioactive, and bactericidal: anodized nanotextured dental implants. Advanced Functional Materials, 34 (30). doi: 10.1002/adfm.202314031
2024
Journal Article
Electrically stimulated dental implants triggers soft‐tissue integration and bactericidal functions
Jayasree, Anjana, Cartmell, Sarah, Ivanovski, Sašo and Gulati, Karan (2024). Electrically stimulated dental implants triggers soft‐tissue integration and bactericidal functions. Advanced Functional Materials, 34 (23) 2311027. doi: 10.1002/adfm.202311027
2024
Journal Article
Load, unload and repeat: understanding the mechanical characteristics of zirconia in dentistry
Chopra, Divya, Guo, Tianqi, Gulati, Karan and Ivanovski, Sašo (2024). Load, unload and repeat: understanding the mechanical characteristics of zirconia in dentistry. Dental Materials, 40 (1), e1-e17. doi: 10.1016/j.dental.2023.10.007
2023
Journal Article
Microvesicle-eluting nano-engineered implants influence inflammatory response of keratinocytes
Jayasree, Anjana, Liu, Chun, Salomon, Carlos, Ivanovski, Sašo, Gulati, Karan and Han, Pingping (2023). Microvesicle-eluting nano-engineered implants influence inflammatory response of keratinocytes. Drug Delivery and Translational Research, 1-14. doi: 10.1007/s13346-023-01457-x
2023
Journal Article
Profiling to probing: atomic force microscopy to characterize nano-engineered implants
Gulati, Karan and Adachi, Taiji (2023). Profiling to probing: atomic force microscopy to characterize nano-engineered implants. Acta Biomaterialia, 170, 15-38. doi: 10.1016/j.actbio.2023.08.006
2023
Journal Article
Fit and forget: the future of dental implant therapy via nanotechnology
Gulati, Karan, Chopra, Divya, Asli Kocak-Oztug, Necla and Verron, Elise (2023). Fit and forget: the future of dental implant therapy via nanotechnology. Advanced Drug Delivery Reviews, 199 114900, 114900. doi: 10.1016/j.addr.2023.114900
2023
Conference Publication
Anodized Dental Implants: Custom Nanotopographies towards Tailored Bioactivity
Gulati, Karan (2023). Anodized Dental Implants: Custom Nanotopographies towards Tailored Bioactivity. Meeting of the European-Chapter of the Tissue-Engineering-and-Regenerative-Medicine-International-Society (TERMIS), Manchester England, Mar 28-31, 2023. NEW ROCHELLE: MARY ANN LIEBERT, INC.
2023
Conference Publication
Fabrication of Anodized Zirconia Dental Implants towards Enhanced Bioactivity
Chopra, Divya, Gulati, Karan, Verron, Elise and Ivanovski, Saso (2023). Fabrication of Anodized Zirconia Dental Implants towards Enhanced Bioactivity. European Chapter of the Tissue-Engineering-and-Regenerative-Medicine-International-Society (TERMIS), Manchester England, Mar 28-31, 2023. NEW ROCHELLE: MARY ANN LIEBERT, INC.
2023
Journal Article
Random, aligned and grassy: bioactivity and biofilm analysis of Zirconia nanostructures as dental implant modification
Chopra, Divya, Jayasree, Anjana, Guo, Tianqi, Gulati, Karan and Ivanovski, Sašo (2023). Random, aligned and grassy: bioactivity and biofilm analysis of Zirconia nanostructures as dental implant modification. Composites Part B: Engineering, 259 110725. doi: 10.1016/j.compositesb.2023.110725
2023
Journal Article
Advancing Nitinol: from heat treatment to surface functionalization for nickel–titanium (NiTi) instruments in endodontics
Chan, Wai-Sze, Gulati, Karan and Peters, Ove A. (2023). Advancing Nitinol: from heat treatment to surface functionalization for nickel–titanium (NiTi) instruments in endodontics. Bioactive Materials, 22, 91-111. doi: 10.1016/j.bioactmat.2022.09.008
2023
Journal Article
Craniofacial therapy: advanced local therapies from nano-engineered titanium implants to treat craniofacial conditions
Gulati, Karan, Ding, Chengye, Guo, Tianqi, Guo, Houzuo, Yu, Huajie and Liu, Yan (2023). Craniofacial therapy: advanced local therapies from nano-engineered titanium implants to treat craniofacial conditions. International Journal of Oral Science, 15 (1) 15, 15. doi: 10.1038/s41368-023-00220-9
2023
Book
Surface modification of titanium dental implants
Karan Gulati ed. (2023). Surface modification of titanium dental implants. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-21565-0
2023
Book Chapter
Local therapy from nano-engineered titanium dental implants
Jayasree, Anjana, Ivanovski, Sašo and Gulati, Karan (2023). Local therapy from nano-engineered titanium dental implants. Surface modification of titanium dental implants. (pp. 153-198) edited by Karan Gulati. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-21565-0_6
2023
Book Chapter
Cytotoxicity, corrosion and electrochemical stability of titanium dental implants
Guo, Tianqi, Scimeca, Jean-Claude, Ivanovski, Sašo, Verron, Elise and Gulati, Karan (2023). Cytotoxicity, corrosion and electrochemical stability of titanium dental implants. Surface modification of titanium dental implants. (pp. 219-253) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-21565-0_8
2023
Book Chapter
From micro to nano: surface modification for enhanced bioactivity of titanium dental implants
Guo, Tianqi, Ivanovski, Sašo and Gulati, Karan (2023). From micro to nano: surface modification for enhanced bioactivity of titanium dental implants. Surface modification of titanium dental implants. (pp. 117-151) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-21565-0_5
2023
Book Chapter
Mechanical stability of anodized nano-engineered titanium dental implants
Chopra, Divya and Gulati, Karan (2023). Mechanical stability of anodized nano-engineered titanium dental implants. Surface modification of titanium dental implants. (pp. 199-218) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-21565-0_7
2023
Journal Article
Tunable nano-engineered anisotropic surface for enhanced mechanotransduction and soft-tissue integration
Han, Pingping, Guo, Tianqi, Jayasree, Anjana, Gomez, Guillermo A., Gulati, Karan and Ivanovski, Sašo (2023). Tunable nano-engineered anisotropic surface for enhanced mechanotransduction and soft-tissue integration. Nano Research, 16 (5), 7293-7303. doi: 10.1007/s12274-023-5379-y
2023
Journal Article
Enhanced corrosion resistance and local therapy from nano-engineered titanium dental implants
Guo, Tianqi, Scimeca, Jean-Claude, Ivanovski, Sašo, Verron, Elise and Gulati, Karan (2023). Enhanced corrosion resistance and local therapy from nano-engineered titanium dental implants. Pharmaceutics, 15 (2) 315, 1-24. doi: 10.3390/pharmaceutics15020315
2022
Journal Article
Influence of clinical decontamination techniques on the surface characteristics of SLA titanium implant
Bayrak, Meltem, Kocak-Oztug, Necla Asli, Gulati, Karan, Cintan, Serdar and Cifcibasi, Emine (2022). Influence of clinical decontamination techniques on the surface characteristics of SLA titanium implant. Nanomaterials, 12 (24) 4481, 1-14. doi: 10.3390/nano12244481
Funding
Past funding
Supervision
Availability
- Dr Karan Gulati is:
- Available for supervision
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Supervision history
Completed supervision
-
2023
Doctor Philosophy
Nano-Engineered Titanium Dental Implants for Tailored Therapy and Bioactivity
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
2023
Doctor Philosophy
Fabrication Optimization of Bioactive Nano-Engineered Titanium Dental Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski, Dr Pingping Han
Media
Enquiries
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