Dr Pingping Han
Dr

Pingping Han

Email: 
Phone: 
+61 7 334 64285

Background

Dr Pingping Han is currently leading the Epigenetic Nanodiagnostics and Therapeutics Group within the Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3), at the UQ School of Dentistry. Dr Han received her PhD in Biomedical Engineering from the Queensland University of Technology (QUT) in 2014. Dr Han's current research focuses on three themes: a) salivary diagnostics for periodontal disease, b) “cell-free” regenerative therapy for periodontal tissue engineering and c) cellular nano-mechanics on different modified biomaterial substrates.

Availability

Dr Pingping Han is:
Available for supervision
Media expert

Fields of research

Biological Sciences Biomedical and Clinical Sciences Biomedical engineering Dentistry Engineering Epigenetics (incl. genome methylation and epigenomics) Genetics Microbial genetics Microbiology Periodontics

Qualifications

  • Doctor of Philosophy, Queensland University of Technology

Research interests

  • Cell-free therapy for periodontal regeneration

  • Saliva diagnosis

  • Epigenetic diagnosis and therapy

  • Periodontal diagnosis and therapy

Search Professor Pingping Han’s works on UQ eSpace

74 works between 2012 and 2025
All (74) Journal Article (71) Book Chapter (3)

61 - 74 of 74 works

2016

Journal Article

Europium-containing mesoporous bioactive glass scaffolds for stimulating in vitro and in vivo osteogenesis

Wu, Chengtie, Xia, Lunguo, Han, Pingping, Mao, Lixia, Wang, Jiacheng, Zhai, Dong, Fang, Bing, Chang, Jiang and Xiao, Yin (2016). Europium-containing mesoporous bioactive glass scaffolds for stimulating in vitro and in vivo osteogenesis. ACS Applied Materials and Interfaces, 8 (18), 11342-11354. doi: 10.1021/acsami.6b03100

Europium-containing mesoporous bioactive glass scaffolds for stimulating in vitro and in vivo osteogenesis

2016

Journal Article

Proinflammatory cytokines regulate cementogenic differentiation of periodontal ligament cells by Wnt/Ca2+ signaling pathway

Han, Pingping, Lloyd, Tain, Chen, Zetao and Xiao, Yin (2016). Proinflammatory cytokines regulate cementogenic differentiation of periodontal ligament cells by Wnt/Ca2+ signaling pathway. Journal of Interferon and Cytokine Research, 36 (5), 328-337. doi: 10.1089/jir.2015.0111

Proinflammatory cytokines regulate cementogenic differentiation of periodontal ligament cells by Wnt/Ca2+ signaling pathway

2015

Journal Article

Graphene-oxide-modified β-tricalcium phosphate bioceramics stimulate in vitro and in vivo osteogenesis

Wu, Chengtie, Xia, Lunguo, Han, Pingping, Xu, Mengchi, Fang, Bing, Wang, Jiacheng, Chang, Jiang and Xiao, Yin (2015). Graphene-oxide-modified β-tricalcium phosphate bioceramics stimulate in vitro and in vivo osteogenesis. Carbon, 93, 116-129. doi: 10.1016/j.carbon.2015.04.048

Graphene-oxide-modified β-tricalcium phosphate bioceramics stimulate in vitro and in vivo osteogenesis

2015

Journal Article

Activation of the Canonical Wnt Signaling Pathway Induces Cementum Regeneration

Han, Pingping, Ivanovski, Saso, Crawford, Ross and Xiao, Yin (2015). Activation of the Canonical Wnt Signaling Pathway Induces Cementum Regeneration. Journal of Bone and Mineral Research, 30 (7), 1160-1174. doi: 10.1002/jbmr.2445

Activation of the Canonical Wnt Signaling Pathway Induces Cementum Regeneration

2014

Journal Article

Lithium release from β-tricalcium phosphate inducing cementogenic and osteogenic differentiation of both hPDLCs and hBMSCs

Han, Pingping, Xu, Mengchi, Chang, Jiang, Chakravorty, Nishant, Wu, Chengtie and Xiao, Yin (2014). Lithium release from β-tricalcium phosphate inducing cementogenic and osteogenic differentiation of both hPDLCs and hBMSCs. Biomaterials Science, 2 (9), 1230-1243. doi: 10.1039/c4bm00111g

Lithium release from β-tricalcium phosphate inducing cementogenic and osteogenic differentiation of both hPDLCs and hBMSCs

2014

Journal Article

A stimulatory effect of Ca3ZrSi2O9 bioceramics on cementogenic/osteogenic differentiation of periodontal ligament cells

Zhang, Xufang, Han, Pingping, Jaiprakash, Anjali, Wu, Chengtie and Xiao, Yin (2014). A stimulatory effect of Ca3ZrSi2O9 bioceramics on cementogenic/osteogenic differentiation of periodontal ligament cells. Journal of Materials Chemistry B, 2 (10), 1415-1423. doi: 10.1039/c3tb21663b

A stimulatory effect of Ca3ZrSi2O9 bioceramics on cementogenic/osteogenic differentiation of periodontal ligament cells

2014

Journal Article

Mussel-inspired bioceramics with self-assembled Ca-P/polydopamine composite nanolayer: Preparation, formation mechanism, improved cellular bioactivity and osteogenic differentiation of bone marrow stromal cells

Wu, Chengtie, Han, Pingping, Liu, Xiaoguo, Xu, Mengchi, Tian, Tian, Chang, Jiang and Xiao, Yin (2014). Mussel-inspired bioceramics with self-assembled Ca-P/polydopamine composite nanolayer: Preparation, formation mechanism, improved cellular bioactivity and osteogenic differentiation of bone marrow stromal cells. Acta Biomaterialia, 10 (1), 428-438. doi: 10.1016/j.actbio.2013.10.013

Mussel-inspired bioceramics with self-assembled Ca-P/polydopamine composite nanolayer: Preparation, formation mechanism, improved cellular bioactivity and osteogenic differentiation of bone marrow stromal cells

2013

Journal Article

The ionic products from bredigite bioceramics induced cementogenic differentiation of periodontal ligament cells via activation of the Wnt/β-catenin signalling pathway

Zhou, Yinghong, Wu, Chengtie, Zhang, Xufang, Han, Pingping and Xiao, Yin (2013). The ionic products from bredigite bioceramics induced cementogenic differentiation of periodontal ligament cells via activation of the Wnt/β-catenin signalling pathway. Journal of Materials Chemistry B, 1 (27), 3380-3389. doi: 10.1039/c3tb20445f

The ionic products from bredigite bioceramics induced cementogenic differentiation of periodontal ligament cells via activation of the Wnt/β-catenin signalling pathway

2013

Journal Article

The effect of silicate ions on proliferation, osteogenic differentiation and cell signalling pathways (WNT and SHH) of bone marrow stromal cells

Han, Pingping, Wu, Chengtie and Xiao, Yin (2013). The effect of silicate ions on proliferation, osteogenic differentiation and cell signalling pathways (WNT and SHH) of bone marrow stromal cells. Biomaterials Science, 1 (4), 379-392. doi: 10.1039/c2bm00108j

The effect of silicate ions on proliferation, osteogenic differentiation and cell signalling pathways (WNT and SHH) of bone marrow stromal cells

2013

Journal Article

Nagelschmidtite bioceramics with osteostimulation properties: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells

Wu, Chengtie, Han, Pingping, Xu, Mengchi, Zhang, Xufang, Zhou, Yinghong, Xue, Guangda, Chang, Jiang and Xiao, Yin (2013). Nagelschmidtite bioceramics with osteostimulation properties: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells. Journal of Materials Chemistry B, 1 (6), 876-885. doi: 10.1039/c2tb00391k

Nagelschmidtite bioceramics with osteostimulation properties: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells

2013

Journal Article

Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity

Wu, Chengtie, Zhou, Yinghong, Xu, Mengchi, Han, Pingping, Chen, Lei, Chang, Jiang and Xiao, Yin (2013). Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity. Biomaterials, 34 (2), 422-433. doi: 10.1016/j.biomaterials.2012.09.066

Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity

2012

Journal Article

The cementogenic differentiation of periodontal ligament cells via the activation of Wnt/β-catenin signalling pathway by Li+ ions released from bioactive scaffolds

Han, Pingping, Wu, Chengtie, Chang, Jiang and Xiao, Yin (2012). The cementogenic differentiation of periodontal ligament cells via the activation of Wnt/β-catenin signalling pathway by Li+ ions released from bioactive scaffolds. Biomaterials, 33 (27), 6370-6379. doi: 10.1016/j.biomaterials.2012.05.061

The cementogenic differentiation of periodontal ligament cells via the activation of Wnt/β-catenin signalling pathway by Li+ ions released from bioactive scaffolds

2012

Journal Article

Porous Ca-Si-based nanospheres: a potential intra-canal disinfectant-carrier for infected canal treatment

Fan, Wei, Wu, Chengtie, Han, Pingping, Zhou, Yinghong and Xiao, Yin (2012). Porous Ca-Si-based nanospheres: a potential intra-canal disinfectant-carrier for infected canal treatment. Materials Letters, 81, 16-19. doi: 10.1016/j.matlet.2012.04.142

Porous Ca-Si-based nanospheres: a potential intra-canal disinfectant-carrier for infected canal treatment

2012

Journal Article

Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering

Wu, Chengtie, Zhou, Yinghong, Fan, Wei, Han, Pingping, Chang, Jiang, Yuen, Jones, Zhang, Meili and Xiao, Yin (2012). Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering. Biomaterials, 33 (7), 2076-2085. doi: 10.1016/j.biomaterials.2011.11.042

Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering

Current funding

  • 2025 - 2027
    Extracellular vesicles and metal particles in saliva and PICF for peri-implantitis: a human clinical study
    International Team for Implantology Foundation
    Open grant
  • 2025 - 2029
    Harnessing Small Extracellular Vesicles for Precision Periodontics
    NHMRC Investigator Grants
    Open grant
  • 2024 - 2025
    Exploring the role of bacterial extracellular vesicles from both saliva biofilm and saliva on Periodontitis pathogenesis
    Australian Dental Research Fund Inc
    Open grant
  • 2023 - 2025
    Treg-derived extracellular vesicles reprogram local immune response for enhanced periodontal regeneration
    Osteology Foundation Young/Advanced Researcher Grant
    Open grant
  • 2023 - 2025
    Understanding resorption patterns in vertically augmented bone
    International Team for Implantology Foundation
    Open grant
  • 2023 - 2026
    Immunoengineered Nanocomposite Surface Coatings towards Soft Tissue Regeneration
    International Team for Implantology Foundation
    Open grant

Past funding

  • 2023 - 2024
    Human osteoblast cell-derived small extracellular vesicles for in vivo periodontal wound healing in a rat model
    Australian Dental Research Fund Inc
    Open grant
  • 2022 - 2023
    Longitudinal profile of salivary extracellular vesicles associated microRNA post-non-surgical periodontal therapy
    Australian Dental Research Fund Inc
    Open grant
  • 2021 - 2022
    Clinical research study to evaluate the effect on gingival inflammation of a toothpaste containing vitamin D in patients with established dental plaque and gingivitis
    Colgate-Palmolive Company
    Open grant
  • 2021 - 2023
    Small extracellular vesicles-loaded titanium nanopores for gingival peri-implant soft tissue barrier
    International Team for Implantology Foundation
    Open grant
  • 2021 - 2022
    Aerosol transmission model and protective strategies
    ADIC Research Funding
    Open grant
  • 2021 - 2023
    Soft tissue insertion into micro-tubules on Ti discs using femtosecond laster micromachining: subtraction modification
    Australian Dental Research Fund Inc
    Open grant
  • 2021 - 2022
    Human salivary circular RNAs profile in periodontal disease - a pilot study
    Australian Dental Research Fund Inc
    Open grant
  • 2021 - 2022
    Non-surgical periodontal therapy with azithromycin: effects on the subgingival microbiome
    Australian Dental Research Fund Inc
    Open grant
  • 2021 - 2022
    Optimizing titanium surface topography and chemistry towrds enhanced soft-tissue integration
    Australian Dental Research Fund Inc
    Open grant
  • 2021 - 2023
    The effects of bioinspired titanium nanostructure on gingival fibroblasts and oral biofilm
    Australian Dental Research Fund Inc
    Open grant
  • 2020 - 2021
    A multiplex bead platform to identify small extracellular vesicle surfaces signatures in periodontitis
    Australian Dental Research Fund Inc
    Open grant
  • 2019 - 2020
    Nano-engineered titanium abutments for enhanced gingival fibroblast functions in vitro
    International Team for Implantology Foundation
    Open grant
  • 2019
    Salivary exosomal DNA methylation: a potential epigenetic biomarker for periodontitis
    UQ Early Career Researcher
    Open grant
  • 2018
    Attending TERMIS World Congress and Workshop in Japan
    Ian Potter Foundation
    Open grant
  • 2017 - 2020
    Discovering novel targets for treating bone loss associated with ageing-related osteoporosis through long non-coding RNA landscapes
    UQ Development Fellowships
    Open grant

Availability

Dr Pingping Han is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Nano-diagnostics for periodontal disease

  • Nano-therapeutics for periodontal regeneration

  • Cellular nano-mechanics on different biomaterial surfaces

  • Omics and epigenetics in dentistry

  • Nano-diagnostics for periodontal disease

  • Periodontal cell derived extracellular vesicles as treatment for periodontitis

    Investigating the potential of periodontal cell-derived extracellular vesicles (EVs) as a 'cell-free' therapy for a chronic oral disease - periodontitis.

  • Cellular nano-mechanics on different biomaterial surfaces

  • Omics and epigenetics in dentistry

  • Periodontal cell derived extracellular vesicles as treatment for periodontitis

    Investigating the potential of periodontal cell-derived extracellular vesicles (EVs) as a 'cell-free' therapy for a chronic oral disease - periodontitis.

  • Nano-diagnostics for periodontal disease

  • Cellular nano-mechanics on different biomaterial surfaces

  • Omics and epigenetics in dentistry

  • Periodontal cell derived extracellular vesicles as treatment for periodontitis

    Investigating the potential of periodontal cell-derived extracellular vesicles (EVs) as a 'cell-free' therapy for a chronic oral disease - periodontitis.

  • Nano-diagnostics for periodontal disease

  • Cellular nano-mechanics on different biomaterial surfaces

  • Omics and epigenetics in dentistry

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Dr Pingping Han directly for media enquiries about:

  • extracellular vesicles
  • Periodontal regeneration
  • periodontitis
  • saliva diagnosis

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communications@uq.edu.au