Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2013
Journal Article
Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study
Greenslade, Jaimi H., Cullen, Louise, Than, Martin, Aldous, Sally, Chu, Kevin, Brown, Anthony F. T., Richards, A. Mark, Pemberton, Christopher J., George, Peter and Parsonage, William A. (2013). Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study. American Journal of Emergency Medicine, 31 (7), 1103-1107. doi: 10.1016/j.ajem.2013.04.016
2013
Journal Article
What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey
Than, Martin, Herbert, Mel, Flaws, Dylan, Cullen, Louise, Hess, Erik, Hollander, Judd E., Diercks, Deborah, Ardagh, Michael W., Kline, Jeffrey A., Munro, Zea and Jaffe, Allan (2013). What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey. International Journal of Cardiology, 166 (3), 752-754. doi: 10.1016/j.ijcard.2012.09.171
2013
Conference Publication
COMPARISON OF HIGHLY SENSITIVE TROPONIN I AND T RESULTS IN THE DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION
Parsonage, William, Cullen, Louise, Greenslade, Jaimi, Tate, Jill, Ungerer, Jacobus, Hammett, Christopher, Pretorius, Carel, Chu, Kevin and Brown, Anthony (2013). COMPARISON OF HIGHLY SENSITIVE TROPONIN I AND T RESULTS IN THE DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION. 62nd Annual Scientific Session of the American-College-of-Cardiology, San Francisco Ca, Mar 09-11, 2013. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/S0735-1097(13)60229-6
2013
Journal Article
Cardiac Risk Stratification Scoring Systems for Suspected Acute Coronary Syndromes in the Emergency Department
Than, M. P., Flaws, D. F., Cullen, L. and Deely, J. M. (2013). Cardiac Risk Stratification Scoring Systems for Suspected Acute Coronary Syndromes in the Emergency Department. Current Emergency and Hospital Medicine Reports, 1 (1), 53-63. doi: 10.1007/s40138-012-0004-0
2013
Journal Article
Comparison of three risk stratification rules for predicting patients with acute coronary syndrome presenting to an australian emergency department
Cullen, L., Greenslade, J., Hammett, C.J., Brown, A.F.T., Chew, D.P., Bilesky, J., Than, M., Lamanna, A., Ryan, K., Chu, K. and Parsonage, W.A. (2013). Comparison of three risk stratification rules for predicting patients with acute coronary syndrome presenting to an australian emergency department. Heart Lung and Circulation, 22 (10), 844-851. doi: 10.1016/j.hlc.2013.03.074
2012
Journal Article
Comparison of early biomarker strategies with the Heart Foundation of Australia/Cardiac Society of Australia and New Zealand guidelines for risk stratification of ED patients with chest pain
Cullen, Louise, Parsonage, William A., Greenslade, Jaimi, Lamanna, Arvin, Hammett, Christopher J., Than, Martin, Ungerer, Jacobus P. J., Chu, Kevin, O'Kane, Shanen and Brown, Anthony F. T. (2012). Comparison of early biomarker strategies with the Heart Foundation of Australia/Cardiac Society of Australia and New Zealand guidelines for risk stratification of ED patients with chest pain. Emergency Medicine Australasia, 24 (6), 595-603. doi: 10.1111/1742-6723.12008
2012
Journal Article
A 2-hour thrombolysis in myocardial infarction score outperforms other risk stratification tools in patients presenting with possible acute coronary syndromes: comparison of chest pain risk stratification tools
Aldous, Sally J., Richards, Mark, Cullen, Louise, Troughton, Richard and Than, Martin (2012). A 2-hour thrombolysis in myocardial infarction score outperforms other risk stratification tools in patients presenting with possible acute coronary syndromes: comparison of chest pain risk stratification tools. American Heart Journal, 164 (4), 516-523. doi: 10.1016/j.ahj.2012.06.025
2012
Journal Article
Highly sensitive troponin assays - a two-edged sword?
Scott, Ian A., Cullen, Louise, Tate, Jillian R. and Parsonage, William (2012). Highly sensitive troponin assays - a two-edged sword?. Medical Journal of Australia, 197 (6), 320-323. doi: 10.5694/mja11.11199
2012
Conference Publication
The HEART score for chest pain patients at the emergency department validated in a multi centre Asia-Pacific population
Backus, B. E., Six, A. J., Cullen, L., Greenslade, J. and Than, M. (2012). The HEART score for chest pain patients at the emergency department validated in a multi centre Asia-Pacific population. Congress of the European-Society-of-Cardiology (ESC), Munchen Germany, Aug 25-29, 2012. OXFORD: OXFORD UNIV PRESS.
2012
Journal Article
2-hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: The ADAPT trial
Than, Martin, Cullen, Louise, Aldous, Sally, Parsonage, William A., Reid, Christopher M., Greenslade, Jaimi, Flaws, Dylan, Hammett, Christopher J., Beam, Daren M., Ardagh, Michael W., Troughton, Richard, Brown, Anthony F.T., George, Peter, Florkowski, Christopher M., Kline, Jeffrey A., Peacock, W. Frank, Maisel, Alan S., Lim, Swee Han, Lamanna, Arvin and Richards, A. Mark (2012). 2-hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: The ADAPT trial. Journal of the American College of Cardiology, 59 (23), 2091-2098. doi: 10.1016/j.jacc.2012.02.035
2012
Journal Article
A new improved accelerated diagnostic protocol safely identifies low-risk patients with chest pain in the emergency department
Aldous, Sally J., Richards, Mark A., Cullen, Louise, Troughton, Richard and Than, Martin (2012). A new improved accelerated diagnostic protocol safely identifies low-risk patients with chest pain in the emergency department. Academic Emergency Medicine, 19 (5), 510-516. doi: 10.1111/j.1553-2712.2012.01352.x
2012
Journal Article
Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain
Aldous, Sally J., Richards, Mark, Cullen, Louise, Troughton, Richard and Than, Martin (2012). Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain. Canadian Medical Association Journal, 184 (5), E260-E268. doi: 10.1503/cmaj.110773
2012
Journal Article
In reply
Aldous, Sally J., Richards, A. Mark, Cullen, Louise and Than, Martin P. (2012). In reply. Clinical Chemistry, 58 (1), 313-314. doi: 10.1373/clinchem.2011.176305
2012
Journal Article
Examining the signs and symptoms experienced by individuals with suspected acute coronary syndrome in the Asia-pacific region: A prospective observational study
Greenslade, Jaimi H., Cullen, Louise, Parsonage, William, Reid, Christopher M., Body, Richard, Richards, Mark, Hawkins, Tracey, Lim, Swee Han and Than, Martin (2012). Examining the signs and symptoms experienced by individuals with suspected acute coronary syndrome in the Asia-pacific region: A prospective observational study. Annals of Emergency Medicine, 60 (6), 777-785. doi: 10.1016/j.annemergmed.2012.05.008
2012
Journal Article
The role of cardiac computed tomography in assessment of acute chest pain
Parsonage, W.A., Cullen, L., Younger, J.F. and Than, M. (2012). The role of cardiac computed tomography in assessment of acute chest pain. Heart, Lung and Circulation, 21 (11), 763-763. doi: 10.1016/j.hlc.2012.04.011
2011
Journal Article
Troponin: A risk-defining biomarker for emergency department physicians
Cullen, Louise (2011). Troponin: A risk-defining biomarker for emergency department physicians. Emergency Medicine Australasia, 23 (4), 391-394. doi: 10.1111/j.1742-6723.2011.01458.x
2011
Conference Publication
The ASia-Pacific Evaluation of Chest pain Trial (ASPECT): two-hour emergency department rule-out evaluation for chest pain
Cullen, L. A., Than, M. P., Reid, C. M., Lim, S. H., Aldous, S., Ardagh, M. and Richards, A. M. (2011). The ASia-Pacific Evaluation of Chest pain Trial (ASPECT): two-hour emergency department rule-out evaluation for chest pain. OXFORD: OXFORD UNIV PRESS.
2011
Conference Publication
Comparison of 2 and 6 hour time intervals in the diagnosis of acute myocardial infarction
Cullen, L. A., Greenslade, J. H., Brown, A. F. T., Hammett, C. J. K., Than, M. P., Chu, K. H., Ungerer, J. P. J. and Parsonage, W. A. (2011). Comparison of 2 and 6 hour time intervals in the diagnosis of acute myocardial infarction. OXFORD: OXFORD UNIV PRESS.
2011
Journal Article
Early dynamic change in high-sensitivity cardiac troponin T in the investigation of acute myocardial infarction
Aldous, Sally J., Richards, A. Mark, Cullen, Louise and Than, Martin P. (2011). Early dynamic change in high-sensitivity cardiac troponin T in the investigation of acute myocardial infarction. Clinical Chemistry, 57 (8), 1154-1160. doi: 10.1373/clinchem.2010.161166
2011
Journal Article
The evolution of Chest pain pathways
Mangleson, Frances Iris Jean, Cullen, Louise and Scott, Adam Charles (2011). The evolution of Chest pain pathways. Critical Pathways in Cardiology, 10 (2), 69-75. doi: 10.1097/HPC.0b013e3182215b48
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
-
Doctor Philosophy
Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study
Principal Advisor
Completed supervision
-
2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
-
2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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