|
2025 Journal Article Transitioning to high-sensitivity troponin: 1-year mortality outcomes in patients with suspected acute coronary syndrome presenting to emergency departmentsHickling, Siobhan, Sanfilippo, Frank M, Cullen, Louise, Chew, Derek P, Hillis, Graham S, Fatovich, Daniel M, Karnon, Jonathon, Rankin, Jamie, Nedkoff, Lee, Scanlan, Samuel, Hickman, Peter E, Stapleton, Stuart, Knuiman, Matthew, Parsonage, William, Mitra, Biswadev, Schneider, Hans G, Wilkes, Garry, Robinson, Teagan and Briffa, Tom (2025). Transitioning to high-sensitivity troponin: 1-year mortality outcomes in patients with suspected acute coronary syndrome presenting to emergency departments. Heart 324959, heartjnl-2024. doi: 10.1136/heartjnl-2024-324959 |
|
2025 Journal Article Prognostic Implications of Machine Learning Algorithm–Supported Diagnostic Classification of Myocardial Injury Using the Fourth Universal Definition of Myocardial InfarctionLambrakis, Kristina, Khan, Ehsan, Liao, Zhibin, Gerlach, Joey, Nelson, Adam J., Goodman, Shaun G., Briffa, Tom, Cullen, Louise, Verjans, Johan and Chew, Derek P. (2025). Prognostic Implications of Machine Learning Algorithm–Supported Diagnostic Classification of Myocardial Injury Using the Fourth Universal Definition of Myocardial Infarction. Heart Lung and Circulation. doi: 10.1016/j.hlc.2024.11.023 |
|
2024 Journal Article Diagnostic accuracy of a machine learning algorithm using point-of-care high-sensitivity cardiac troponin I for rapid rule-out of myocardial infarction: a retrospective studyToprak, Betül, Solleder, Hugo, Di Carluccio, Eleonora, Greenslade, Jaimi H, Parsonage, William A, Schulz, Karen, Cullen, Louise, Apple, Fred S, Ziegler, Andreas, Blankenberg, Stefan, Stephensen, Laura, Brownlee, Emily, McCormick, Ellyse, Fincher, Gavin, Hall, Emma J., Hancock, Rebecca, Gaikwad, Niranjan, Gangathimmaiah, Vinay, Hamilton-Craig, Christian, Hobbins-King, Andrew, Keijzers, Gerben, Bayat, Maryam Khorramshahi, Mahmoodi, Ehsan, Perez, Siegfried, Ranasinghe, Isuru, Staib, Andrew, Zournazi, Anna and Than, Martin (2024). Diagnostic accuracy of a machine learning algorithm using point-of-care high-sensitivity cardiac troponin I for rapid rule-out of myocardial infarction: a retrospective study. The Lancet Digital Health, 6 (10), e729-e738. doi: 10.1016/s2589-7500(24)00191-2 |
|
2024 Journal Article Point-of-care high-sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 hCullen, Louise, Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Smith, Stephen W, Sandoval, Yader, Ranasinghe, Isuru, Gaikwad, Niranjan, Khorramshahi Bayat, Maryam, Mahmoodi, Ehsan, Schulz, Karen, Than, Martin, Apple, Fred S, Brownlee, Emily, Fincher, Gavin, Hall, Emma, Hancock, Rebecca, Gangathimmaiah, Vinay, Hamilton-Craig, Christian, Hobbins-King, Andrew, Keijzers, Gerben, McCormick, Ellyse, Perez, Siegfried, Staib, Andrew, Zournazi, Anna, Than, Martin and the SAMIE and SEIGE investigators (2024). Point-of-care high-sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 h. European Heart Journal, 45 (28), 2508-2515. doi: 10.1093/eurheartj/ehae343 |
|
2024 Journal Article Machine-Learning for Phenotyping and Prognostication of Myocardial Infarction and Injury in Suspected Acute Coronary SyndromeKhan, Ehsan, Lambrakis, Kristina, Liao, Zhibin, Gerlach, Joey, Briffa, Tom, Cullen, Louise, Nelson, Adam J., Verjans, Johan and Chew, Derek P. (2024). Machine-Learning for Phenotyping and Prognostication of Myocardial Infarction and Injury in Suspected Acute Coronary Syndrome. JACC: Advances, 3 (9) 101011, 101011. doi: 10.1016/j.jacadv.2024.101011 |
|
2024 Journal Article Protocol for Improving Care by FAster risk-STratification through use of high sensitivity point-of-care troponin in patients presenting with possible acute coronary syndrome in the EmeRgency department (ICare-FASTER): a stepped-wedge cluster randomised quality improvement initiativePickering, John W., Devlin, Gerard, Body, Richard, Aldous, Sally, Jaffe, Allan S., Apple, Fred S., Mills, Nicholas, Troughton, Richard W., Kavsak, Peter, Peacock, W. Frank, Cullen, Louise, Müller, Christian, Lord, Sarah J., Joyce, Laura, Frampton, Chris, Lacey, Cameron James, Richards, Arthur M., Pitama, Suzanne and Than, Martin (2024). Protocol for Improving Care by FAster risk-STratification through use of high sensitivity point-of-care troponin in patients presenting with possible acute coronary syndrome in the EmeRgency department (ICare-FASTER): a stepped-wedge cluster randomised quality improvement initiative. BMJ Open, 14 (6) e083752, 1-11. doi: 10.1136/bmjopen-2023-083752 |
|
2024 Journal Article Clinical decision support using machine learning and natriuretic peptides for the diagnosis of acute heart failureLee, Kuan Ken, Doudesis, Dimitrios, Mair, Johannes, Mills, Nicholas L, Lindahl, Bertil, Boeddinghaus, Jasper, Cullen, Louise, Daniels, Lori, Hammarsten, Ola, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan S, Kimenai, Dorien M, Krychtiuk, Konstantin, Möckel, Martin, Mueller, Christian, Thielmann, Matthias, Thygesen, Kristian, Mair, Johannes, Mills, Nicholas L and the Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2024). Clinical decision support using machine learning and natriuretic peptides for the diagnosis of acute heart failure. European Heart Journal: Acute Cardiovascular Care, 13 (6) zuae064, 515-516. doi: 10.1093/ehjacc/zuae064 |
|
2024 Journal Article How to use natriuretic peptides in non-cardiac surgeryDuceppe, Emmanuelle, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias, Jaffe, Allan S and Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2024). How to use natriuretic peptides in non-cardiac surgery. European Heart Journal: Acute Cardiovascular Care, 13 (4), 380-382. doi: 10.1093/ehjacc/zuae038 |
|
2024 Journal Article Derivation and validation of thresholds using synthetic data methods for single-test screening of emergency department patients with possible acute myocardial infarction using a point-of-care troponin assayPickering, John W, Young, Joanna M, George, Peter M, Watson, Antony S, Aldous, Sally J, Verryt, Toby, Troughton, Richard W, Pemberton, Christopher J, Richards, A Mark, Cullen, Louise A, Apple, Fred S and Than, Martin P (2024). Derivation and validation of thresholds using synthetic data methods for single-test screening of emergency department patients with possible acute myocardial infarction using a point-of-care troponin assay. The Journal of Applied Laboratory Medicine, 9 (3), 526-539. doi: 10.1093/jalm/jfae001 |
|
2024 Journal Article Lower limits for reporting high-sensitivity cardiac troponin assays and impact of analytical performance on patient misclassificationAakre, Kristin M., Apple, Fred S., Mills, Nicolas L., Meex, Steven J.R., Collinson, Paul O., on behalf of the International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB), Hammarsten, Ola, Jaffe, Allan S., Omland, Torbjørn, Cullen, Louise (International Federation of Clinical Chemistry (IFCC) Committee on Clinical Applications of Cardiac Biomarkers (C-CB) member) and Sandoval, Yader (2024). Lower limits for reporting high-sensitivity cardiac troponin assays and impact of analytical performance on patient misclassification. Clinical Chemistry, 70 (3), 497-505. doi: 10.1093/clinchem/hvad185 |
|
2024 Journal Article Behavioural ‘nudging’ interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2×2 factorial, before-after, cluster randomised trialAltinger, Gemma, Sharma, Sweekriti, Maher, Chris G, Cullen, Louise, McCaffery, Kirsten, Linder, Jeffrey A, Buchbinder, Rachelle, Harris, Ian A, Coiera, Enrico, Li, Qiang, Howard, Kirsten, Coggins, Andrew, Middleton, Paul M, Gunja, Naren, Ferguson, Ian, Chan, Trevor, Tambree, Karen, Varshney, Ajay and Traeger, Adrian C (2024). Behavioural ‘nudging’ interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2×2 factorial, before-after, cluster randomised trial. BMJ Open, 14 (3) e079870, 1-12. doi: 10.1136/bmjopen-2023-079870 |
|
2024 Journal Article External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarctionCullen, Louise, Greenslade, Jaimi H., Stephensen, Laura, Ranasinghe, Isuru, Gaikwad, Niranjan, Khorramshahi Bayat, Maryam, Mahmoodi, Ehsan, Than, Martin, Apple, Fred, Parsonage, William and SAMIE study group 2022 (2024). External validation of a rapid algorithm using high-sensitivity troponin assay results for evaluating patients with suspected acute myocardial infarction. Emergency Medicine Journal, 41 (5), 313-319. doi: 10.1136/emermed-2023-213539 |
|
2024 Journal Article Biomarkers for diagnosis and prognostication of acute aortic syndromesMorello, Fulvio, Nazerian, Peiman, Lupia, Enrico, Castelli, Matteo, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias, Jaffe, Allan S. and the Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2024). Biomarkers for diagnosis and prognostication of acute aortic syndromes. European Heart Journal: Acute Cardiovascular Care, 13 (2), 254-256. doi: 10.1093/ehjacc/zuae011 |
|
2023 Journal Article Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study designThulin, Ingrid Viola Lavesson, Jordalen, Silje Marie Farestveit, Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole Thomas, Collinson, Paul, Apple, Fred, Cullen, Louise, Norekval, Tone M., Wisloff, Torbjorn, Vikenes, Kjell, Omland, Torbjorn, Bjorneklett, Rune O. and Aakre, Kristin Moberg (2023). Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design. Scandinavian Cardiovascular Journal, 57 (1) 2272585, 1-7. doi: 10.1080/14017431.2023.2272585 |
|
2023 Journal Article Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trialsLambrakis, Kristina, Khan, Ehsan, van den Merkhof, Anke, Papendick, Cynthia, Chuang, Anthony, Zhai, Yuze, Eng-Frost, Joanne, Rocheleau, Simon, Lehman, Sam J., Blyth, Andrew, Briffa, Tom, Quinn, Stephen, French, John K., Cullen, Louise and Chew, Derek P. (2023). Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials. International Journal of Cardiology, 393 131396, 1-8. doi: 10.1016/j.ijcard.2023.131396 |
|
2023 Journal Article Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assayMeek, Robert, Cullen, Louise, Lu, Zhong, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2023). Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay. EMA - Emergency Medicine Australasia, 35 (6), 1005-1012. doi: 10.1111/1742-6723.14282 |
|
2023 Journal Article Cardiac troponin T and I: back to basicsMingels, Alma M., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias and Study Group on Biomarkers of the ESC Association for Acute CardioVascular Care (2023). Cardiac troponin T and I: back to basics. European Heart Journal: Acute Cardiovascular Care, 12 (9), 631-632. doi: 10.1093/ehjacc/zuad084 |
|
2023 Journal Article Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocolSchults, Jessica A., Marsh, Nicole, Ullman, Amanda J., Kleidon, Tricia M., Ware, Robert S., Byrnes, Joshua, Young, Emily, Hall, Lisa, Keijzers, Gerben, Cullen, Louise, Calleja, Pauline, McTaggart, Steven, Peters, Nathan, Watkins, Stuart, Corley, Amanda, Brown, Christine, Lin, Zhen, Williamson, Frances, Burgess, Luke, Macfarlane, Fiona, Cooke, Marie, Battley, Callan and Rickard, Claire M. (2023). Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol. BMC Health Services Research, 23 (1) 587, 1-12. doi: 10.1186/s12913-023-09499-0 |
|
2023 Journal Article Healthcare cost burden of acute chest pain presentationsDawson, Luke, Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew, Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2023). Healthcare cost burden of acute chest pain presentations. Emergency Medicine Journal, 40 (6) emermed-2022-212674, 1-7. doi: 10.1136/emermed-2022-212674 |
|
2023 Journal Article Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndromeStephensen, Laura, Greenslade, Jaimi, Starmer, Katrina, Starmer, Greg, Stone, Richard, Bonnin, Robert, Brazzale, Anthony, Drahm‐Butler, Tileah, Campbell, Virginia, Davis, Tania, Mowatt, Elizabeth, Brown, Nathan, Proctor, Karlie, Ashover, Sarah, Milburn, Tanya, McCormack, Louise, Graves, Nicholas, Gatton, Michelle, Mahoney, Ray, Parsonage, William and Cullen, Louise (2023). Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome. Emergency Medicine Australasia, 35 (3), 442-449. doi: 10.1111/1742-6723.14138 |
