Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2015
Journal Article
A Clinical Decision Rule to Identify Emergency Department Patients at Low Risk for Acute Coronary Syndrome Who Do Not Need Objective Coronary Artery Disease Testing: The No Objective Testing Rule
Greenslade, Jaimi H., Parsonage, William, Than, Martin, Scott, Adam, Aldous, Sally, Pickering, John W., Hammett, Christopher J. and Cullen, Louise (2015). A Clinical Decision Rule to Identify Emergency Department Patients at Low Risk for Acute Coronary Syndrome Who Do Not Need Objective Coronary Artery Disease Testing: The No Objective Testing Rule. Annals of Emergency Medicine, 67 (4), 478-489.e2. doi: 10.1016/j.annemergmed.2015.08.006
2015
Journal Article
The utility of presentation and 4-hour high sensitivity troponin I to rule-out acute myocardial infarction in the emergency department
Pickering, John W., Young, Joanna M., George, Peter, Aldous, Sally, Cullen, Louise, Greenslade, Jaimi H., Richards, A. Mark, Troughton, Richard, Ardagh, Michael, Frampton, Christopher M. and Than, Martin P. (2015). The utility of presentation and 4-hour high sensitivity troponin I to rule-out acute myocardial infarction in the emergency department. Clinical Biochemistry, 48 (18), 1219-1224. doi: 10.1016/j.clinbiochem.2015.07.033
2015
Journal Article
High-Sensitivity Cardiac Troponin T Concentrations below the Limit of Detection to Exclude Acute Myocardial Infarction: A Prospective Evaluation
Body, Richard, Burrows, Gillian, Carley, Simon, Cullen, Louise, Than, Martin, Jaffe, Allan S and Lewis, Philip S (2015). High-Sensitivity Cardiac Troponin T Concentrations below the Limit of Detection to Exclude Acute Myocardial Infarction: A Prospective Evaluation. Clinical Chemistry, 61 (7), 983-989. doi: 10.1373/clinchem.2014.231530
2015
Journal Article
Two-hour diagnostic algorithms for early assessment of patients with acute chest pain - Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile
Eggers, Kai M, Aldous, Sally, Greenslade, Jaimi H, Johnston, Nina, Lindahl, Bertil, Parsonage, William A, Pickering, John W, Than, Martin and Cullen, Louise (2015). Two-hour diagnostic algorithms for early assessment of patients with acute chest pain - Implications of lowering the cardiac troponin I cut-off to the 97.5th percentile. Clinica Chimica Acta, 445, 19-24. doi: 10.1016/j.cca.2015.03.002
2015
Journal Article
Cost and outcomes of assessing patients with chest pain in an Australian emergency department
Cullen, Louise, Greenslade, Jaimi, Merollini, Katharina, Graves, Nicholas, Hammett, Christopher J. K., Hawkins, Tracey, Than, Martin P., Brown, Anthony F. T., Huang, Christopher B., Panahi, Seyed E., Dalton, Emily and Parsonage, William A. (2015). Cost and outcomes of assessing patients with chest pain in an Australian emergency department. Medical Journal of Australia, 202 (8), 427-432. doi: 10.5694/mja14.00472
2015
Journal Article
Utility of Routine Exercise Stress Testing among Intermediate Risk Chest Pain Patients Attending an Emergency Department
Greenslade, Jaimi H, Parsonage, William, Ho, Ariel, Scott, Adam, Dalton, Emily, Hammett, Christopher, Brown, Anthony F.T, Parker, Kate and Cullen, Louise (2015). Utility of Routine Exercise Stress Testing among Intermediate Risk Chest Pain Patients Attending an Emergency Department. Heart Lung and Circulation, 24 (9), 879-884. doi: 10.1016/j.hlc.2015.03.025
2015
Journal Article
Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients
Meller, Bernadette, Cullen, Louise, Parsonage, William A., Greenslade, Jaimi H., Aldous, Sally, Reichlin, Tobias, Wildi, Karin, Twerenbold, Raphael, Jaeger, Cedric, Hillinger, Petra, Haaf, Philip, Puelacher, Christian, Kern, Vera, Rentsch, Katharina, Stallone, Fabio, Rubini Gimenez, Maria, Ballarino, Paola, Bassetti, Stefano, Walukiewicz, Astrid, Troughton, Richard, Pemberton, Christopher J., Richards, A. Mark, Chu, Kevin, Reid, Christopher M., Than, Martin and Mueller, Christian (2015). Accelerated diagnostic protocol using high-sensitivity cardiac troponin T in acute chest pain patients. International Journal of Cardiology, 184 (1), 208-15. doi: 10.1016/j.ijcard.2015.02.006
2015
Journal Article
Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T
Reichlin, Tobias, Cullen, Louise, Parsonage, William A., Greenslade, Jaimi, Twerenbold, Raphael, Moehring, Berit, Wildi, Karin, Mueller, Sandra, Zellweger, Christa, Mosimann, Tamina, Rubini Gimenez, Maria, Rentsch, Katharina, Osswald, Stefan and Muller, Christian (2015). Two-hour algorithm for triage toward rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. American Journal of Medicine, 128 (4), 369-379.e4. doi: 10.1016/j.amjmed.2014.10.032
2015
Journal Article
Combining presentation high-sensitivity cardiac troponin I and glucose measurements to rule-out an acute myocardial infarction in patients presenting to emergency department with chest pain
Greenslade, J. H., Kavsak, P., Parsonage, W., Shortt, C., Than, M., Pickering, J. W., Aldous, S. and Cullen, L. (2015). Combining presentation high-sensitivity cardiac troponin I and glucose measurements to rule-out an acute myocardial infarction in patients presenting to emergency department with chest pain. Clinical Biochemistry, 48 (4-5), 288-291. doi: 10.1016/j.clinbiochem.2014.11.019
2015
Journal Article
A novel diagnostic protocol to identify patients suitable for discharge after a single high-sensitivity troponin
Carlton, Edward W, Cullen, Louise, Than, Martin, Gamble, James, Khattab, Ahmed and Greaves, Kim (2015). A novel diagnostic protocol to identify patients suitable for discharge after a single high-sensitivity troponin. Heart, 101 (13), 1041-1046. doi: 10.1136/heartjnl-2014-307288
2015
Journal Article
Polylactide Bioabsorbable Struts for Chest Wall Reconstruction in a Pediatric Patient
Makarawo, Tafadzwa P., Reynolds, Richard A. and Cullen, Marc L. (2015). Polylactide Bioabsorbable Struts for Chest Wall Reconstruction in a Pediatric Patient. Annals of Thoracic Surgery, 99 (2), 689-691. doi: 10.1016/j.athoracsur.2014.03.052
2015
Journal Article
Availability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry
Cullen, Louise, French, John K, Briffa, Tom G, Redfern, Julie, Hammett, Christopher J K, Brieger, David B, Parsonage, William A, Lefkovits, Jeffrey, Ellis, Chris, Astley, Carolyn, Howell, Tegwen Eleanor, Elliott, John M and Chew, Derek P B (2015). Availability of highly sensitive troponin assays and acute coronary syndrome care: insights from the SNAPSHOT registry. Medical Journal of Australia, 202 (1), 36-39. doi: 10.5694/mja13.00275
2015
Journal Article
Admission glycaemia and its association with acute coronary syndrome in Emergency Department patients with chest pain
Gardner, Logan S, Nguyen-Pham, Sallyanne, Greenslade, Jaimi H, Parsonage, William, D'Emden, Michael, Than, Martin, Aldous, Sally, Brown, Anthony and Cullen, Louise (2015). Admission glycaemia and its association with acute coronary syndrome in Emergency Department patients with chest pain. Emergency Medicine Journal, 32 (8), 608-612. doi: 10.1136/emermed-2014-204046
2014
Journal Article
Comparison of new point-of-care troponin assay with high sensitivity troponin in diagnosing myocardial infarction
Aldous, Sally, Richards, A. Mark, George, Peter M., Cullen, Louise, Parsonage, William A., Flaws, Dylan, Florkowski, Christopher M., Troughton, Richard W., O'Sullivan, Jack W., Reid, Christopher M., Bannister, Laura and Than, Martin (2014). Comparison of new point-of-care troponin assay with high sensitivity troponin in diagnosing myocardial infarction. International Journal of Cardiology, 177 (1), 182-186. doi: 10.1016/j.ijcard.2014.09.026
2014
Journal Article
Decision limits and the reporting of cardiac troponin: Meeting the needs of both the cardiologist and the ED physician
Hickman, Peter E., Lindahl, Bertil, Cullen, Louise, Koerbin, Gus, Tate, Jill and Potter, Julia M. (2014). Decision limits and the reporting of cardiac troponin: Meeting the needs of both the cardiologist and the ED physician. Critical Reviews in Clinical Laboratory Sciences, 52 (1), 28-44. doi: 10.3109/10408363.2014.972497
2014
Journal Article
The promise of high‐sensitivity troponin testing
Chew, Derek P B and Cullen, Louise (2014). The promise of high‐sensitivity troponin testing. Medical Journal of Australia, 201 (3), 125-126. doi: 10.5694/mja14.00858
2014
Journal Article
Undetectable hs-cTnT in the Emergency Department and Risk of Myocardial Infarction
Cullen, Louise, Than, Martin and Peacock, W. Frank (2014). Undetectable hs-cTnT in the Emergency Department and Risk of Myocardial Infarction. Journal of the American College of Cardiology, 64 (6), 632-633. doi: 10.1016/j.jacc.2014.04.061
2014
Journal Article
Towards a consistent definition of a significant delta troponin with z-scores: a way out of chaos?
Pretorius, Carel J., Cullen, Louise, Parsonage, William A., Greenslade, Jaimi H., Tate, Jillian R., Wilgen, Urs and Ungerer, Jacobus P. J. (2014). Towards a consistent definition of a significant delta troponin with z-scores: a way out of chaos?. European Heart Journal: Acute Cardiovascular Care, 3 (2), 149-157. doi: 10.1177/2048872613517084
2014
Journal Article
Use of Observed Within-Person Variation of Cardiac Troponin in Emergency Department Patients for Determination of Biological Variation and Percentage and Absolute Reference Change Values
Simpson, Aaron J, Potter, Julia M, Koerbin, Gus, Oakman, Carmen, Cullen, Louise, Wilkes, Garry J, Scanlan, Samuel L, Parsonage, William and Hickman, Peter E (2014). Use of Observed Within-Person Variation of Cardiac Troponin in Emergency Department Patients for Determination of Biological Variation and Percentage and Absolute Reference Change Values. Clinical Chemistry, 60 (6), 848-854. doi: 10.1373/clinchem.2013.219410
2014
Journal Article
Limited utility of exercise stress testing in the evaluation of suspected acute coronary syndrome in patients aged less than 40 years with intermediate risk features
Scott, Adam C., Bilesky, Jennifer, Lamanna, Arvin, Cullen, Louise, Brown, Anthony F. T., Denaro, Charles and Parsonage, William (2014). Limited utility of exercise stress testing in the evaluation of suspected acute coronary syndrome in patients aged less than 40 years with intermediate risk features. EMA - Emergency Medicine Australasia, 26 (2), 170-176. doi: 10.1111/1742-6723.12222
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study
Principal Advisor
-
Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
Completed supervision
-
2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
-
2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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