Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

268 works between 2004 and 2025
All (268) Journal Article (232) Conference Publication (36)

141 - 160 of 268 works

2017

Journal Article

Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes

Cullen, Louise, Greenslade, Jaimi H., Hawkins, Tracey, Hammett, Chris, O'Kane, Shanen, Ryan, Kimberley, Parker, Kate, Schluter, Jessica, Dalton, Emily, Brown, Anthony F. T., Than, Martin, Peacock, W. Frank, Jaffe, Allan, O'Rourke, Peter K. and Parsonage, William A. (2017). Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes. Medical Journal of Australia, 207 (5), 195-200. doi: 10.5694/mja16.01351

Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes

2017

Journal Article

Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain

Greenslade, Jaimi H., Nayer, Robert, Parsonage, William, Doig, Shaela, Young, Joanna, Pickering, John W., Than, Martin, Hammett, Christopher and Cullen, Louise (2017). Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain. Emergency Medicine Journal, 34 (8), 517-523. doi: 10.1136/emermed-2016-206366

Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain

2017

Conference Publication

Diagnosis of acute myocardial infarction in patients presenting with left bundle branch block

Nestelberger, T., Cullen, L., Lindahl, B., Reichlin, T., Greenslade, J., Giannitsis, E., Christ, M., Morawiec, B., Miro, O., Martin-Sanchez, J., Boeddinghaus, J., Badertscher, B., De lavallaz, J. Du Fay, Puelacher, C. and Mueller, C. (2017). Diagnosis of acute myocardial infarction in patients presenting with left bundle branch block. OXFORD: OXFORD UNIV PRESS.

Diagnosis of acute myocardial infarction in patients presenting with left bundle branch block

2017

Conference Publication

24-hour patterning of different syncope etiologies in patients presenting to the emergency department

De Lavallaz, J. Du Fay, Badertscher, P., Nestelberger, T., Cullen, L., Than, M., Miro, O., Martin-Sanchez, J., Morawiec, B., Christ, M., Di Somma, S., Peacock, F., Reichlin, T., Osswald, S. and Mueller, C. (2017). 24-hour patterning of different syncope etiologies in patients presenting to the emergency department. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.

24-hour patterning of different syncope etiologies in patients presenting to the emergency department

2017

Conference Publication

Diagnostic accuracy of cardiovascular risk factors for an acute coronary syndrome

Gimenez, M. Rubini, Cullen, L., Than, M., Greenslade, J., Twerenbold, R., Boeddinghaus, J., Nestelberger, T., Wildi, K., Badertscher, P., Pickering, J. and Mueller, C. (2017). Diagnostic accuracy of cardiovascular risk factors for an acute coronary syndrome. OXFORD: OXFORD UNIV PRESS.

Diagnostic accuracy of cardiovascular risk factors for an acute coronary syndrome

2017

Journal Article

A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study

Papendick, Cynthia, Blyth, Andrew, Seshadri, A., Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise, Quinn, Stephen, Karnon, Jon, Chuang, Anthony, Nelson, Adam J., Horsfall, Matthew, Morton, Erin and Chew, Derek P. (2017). A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study. American Heart Journal, 190, 25-33. doi: 10.1016/j.ahj.2017.05.004

A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study

2017

Conference Publication

Pro-hormones in the early diagnosis of cardiac syncope

Badertscher, P., Nestelberg, T., De Lavallaz, J. Du Fay, Than, M., Morawiec, B., Miro, O., Martin-Sanchez, F. J., Cullen, L., Christ, M., Di Somma, S., Peacock, F., Osswald, S., Reichlin, T. and Mueller, C. (2017). Pro-hormones in the early diagnosis of cardiac syncope. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.

Pro-hormones in the early diagnosis of cardiac syncope

2017

Conference Publication

Natural history of syncope: insights from the BASEL IX study

Badertscher, P., Nestelberger, T., De Lavallaz, J. Du Fay, Than, M., Cullen, L., Miro, O., Martin-Sanchez, F. J., Morawiec, B., Christ, M., Di Somma, S., Peacock, F., Osswald, S., Reichlin, T. and Mueller, C. (2017). Natural history of syncope: insights from the BASEL IX study. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.

Natural history of syncope: insights from the BASEL IX study

2017

Journal Article

Comparing the no objective testing rule to the HEART pathway

Greenslade, Jaimi and Cullen, Louise (2017). Comparing the no objective testing rule to the HEART pathway. Academic Emergency Medicine, 24 (9), 1169-1170. doi: 10.1111/acem.13240

Comparing the no objective testing rule to the HEART pathway

2017

Journal Article

Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm

Wildi, Karin, Cullen, Louise, Twerenbold, Raphael, Greenslade, Jaimi H., Parsonage, William, Boeddinghaus, Jasper, Nestelberger, Thomas, Sabti, Zaid, Rubini-Gimenez, Maria, Puelacher, Christian, Cupa, Janosch, Schumacher, Lukas, Badertscher, Patrick, Grimm, Karin, Kozhuharov, Nikola, Stelzig, Claudia, Freese, Michael, Rentsch, Katharina, Lohrmann, Jens, Kloos, Wanda, Buser, Andreas, Reichlin, Tobias, Pickering, John W., Than, Martin and Mueller, Christian (2017). Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm. Clinical Chemistry, 63 (7), 1227-1236. doi: 10.1373/clinchem.2016.268359

Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm

2017

Journal Article

The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis

Jülicher, Paul, Greenslade, Jaimi H, Parsonage, William A and Cullen, Louise (2017). The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis. BMJ Open, 7 (6) e013653, e013653. doi: 10.1136/bmjopen-2016-013653

The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis

2017

Journal Article

Rational clinical evaluation of suspected acute coronary syndromes: The value of more information

Hancock, David G., Chuang, Ming-Yu Anthony, Bystrom, Rebecca, Halabi, Amera, Jones, Rachel, Horsfall, Matthew, Cullen, Louise, Parsonage, William A. and Chew, Derek P. (2017). Rational clinical evaluation of suspected acute coronary syndromes: The value of more information. Emergency Medicine Australasia, 29 (6), 664-671. doi: 10.1111/1742-6723.12819

Rational clinical evaluation of suspected acute coronary syndromes: The value of more information

2017

Journal Article

European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department

Miro, Oscar, Peacock, Frank W., McMurray, John J., Bueno, Hector, Christ, Michael, Maisel, Alan S., Cullen, Louise, Cowie, Martin R., Di Somma, Salvatore, Martin Sanchez, Francisco J., Platz, Elke, Masip, Josep, Zeymer, Uwe, Vrints, Christiaan, Price, Susanna, Mebazaa, Alexander and Mueller, Christian (2017). European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department. European Heart Journal-Acute Cardiovascular Care, 6 (4), 311-320. doi: 10.1177/2048872616633853

European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department

2017

Journal Article

Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis

Pickering, John W., Than, Martin P., Cullen, Louise, Aldous, Sally, Ter Avest, Ewoud, Body, Richard, Carlton, Edward W., Collinson, Paul, Dupuy, Anne Marie, Ekelund, Ulf, Eggers, Kai M., Florkowski, Christopher M., Freund, Yonathan, George, Peter, Goodacre, Steve, Greenslade, Jaimi H., Jaffe, Allan S., Lord, Sarah J., Mokhtari, Arash, Mueller, Christian, Munro, Andrew, Mustapha, Sebbane, Parsonage, William, Peacock, W. Frank, Pemberton, Christopher, Richards, A. Mark, Sanchis, Juan, Staub, Lukas P., Troughton, Richard ... Young, Joanna (2017). Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis. Annals of Internal Medicine, 166 (10), 715-724. doi: 10.7326/M16-2562

Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis

2017

Journal Article

Echocardiography and lung ultrasonography for the assessment and management of acute heart failure

Price, Susanna, for the Acute Heart Failure Study Group of the European Society of Cardiology Acute Cardiovascular Care Association, Platz, Elke, Cullen, Louise, Tavazzi, Guido, Christ, Michael, Cowie, Martin R., Maisel, Alan S., Masip, Josep, Miro, Oscar, McMurray, John J., Peacock, W. Frank, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Bueno, Hector, Zeymer, Uwe and Mueller, Christian (2017). Echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nature Reviews Cardiology, 14 (7), 427-440. doi: 10.1038/nrcardio.2017.56

Echocardiography and lung ultrasonography for the assessment and management of acute heart failure

2017

Journal Article

Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction"

Than, Martin P., Pickering, John W., Cullen, Louise and Kavsak, Peter A. (2017). Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction". Circulation, 135 (16), e923-e924. doi: 10.1161/CIRCULATIONAHA.117.027479

Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction"

2017

Journal Article

Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study

Lavery, Tim, Greenslade, Jaimi H., Parsonage, William A., Hawkins, Tracey, Dalton, Emily, Hammett, Christopher and Cullen, Louise (2017). Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study. Emergency Medicine Australasia, 29 (2), 210-216. doi: 10.1111/1742-6723.12735

Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study

2017

Journal Article

Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI

Tan, Jack Wei Chieh, Lam, Carolyn S. P., Kasim, Sazzli Shahlan, Aw, Tar Choon, Abanilla, Joel M., Chang, Wei-Ting, Dang, Van Phuoc, Iboleon-Dy, Maria, Mumpuni, Sari Sri, Phommintikul, Arintaya, Ta, Manh Cuong, Topipat, Punkiat, Yiu, Kai Hang and Cullen, Louise (2017). Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI. Heart Asia, 9 (1) e000357, 81-87. doi: 10.1136/heartasia-2016-010818

Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI

2017

Journal Article

The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain

Knowlman, Thomas, Greenslade, Jaimi H., Parsonage, William, Hawkins, Tracey, Ruane, Lorcan, Martin, Paul, Prasad, Sandhir, Lancini, Daniel and Cullen, Louise (2017). The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain. Academic Emergency Medicine, 24 (3), 344-352. doi: 10.1111/acem.13123

The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain

2017

Journal Article

The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol

Huis in ’t Veld, Maite Anna, Cullen, Louise, Mahler, Simon A., Backus, Barbra E., Dezman, Zachary D.W. and Mattu, Amal (2017). The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol. Western Journal of Emergency Medicine, 18 (3), 474-478. doi: 10.5811/westjem.2016.12.32676

The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol

Current funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant

Past funding

  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study

    Principal Advisor

  • Doctor Philosophy

    Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study

    Principal Advisor

Completed supervision

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