
Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2017
Journal Article
Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes
Cullen, Louise, Greenslade, Jaimi H., Hawkins, Tracey, Hammett, Chris, O'Kane, Shanen, Ryan, Kimberley, Parker, Kate, Schluter, Jessica, Dalton, Emily, Brown, Anthony F. T., Than, Martin, Peacock, W. Frank, Jaffe, Allan, O'Rourke, Peter K. and Parsonage, William A. (2017). Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes. Medical Journal of Australia, 207 (5), 195-200. doi: 10.5694/mja16.01351
2017
Journal Article
Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain
Greenslade, Jaimi H., Nayer, Robert, Parsonage, William, Doig, Shaela, Young, Joanna, Pickering, John W., Than, Martin, Hammett, Christopher and Cullen, Louise (2017). Validating the Manchester Acute Coronary Syndromes (MACS) and Troponin-only Manchester Acute Coronary Syndromes (T-MACS) rules for the prediction of acute myocardial infarction in patients presenting to the emergency department with chest pain. Emergency Medicine Journal, 34 (8), 517-523. doi: 10.1136/emermed-2016-206366
2017
Conference Publication
Diagnosis of acute myocardial infarction in patients presenting with left bundle branch block
Nestelberger, T., Cullen, L., Lindahl, B., Reichlin, T., Greenslade, J., Giannitsis, E., Christ, M., Morawiec, B., Miro, O., Martin-Sanchez, J., Boeddinghaus, J., Badertscher, B., De lavallaz, J. Du Fay, Puelacher, C. and Mueller, C. (2017). Diagnosis of acute myocardial infarction in patients presenting with left bundle branch block. OXFORD: OXFORD UNIV PRESS.
2017
Conference Publication
24-hour patterning of different syncope etiologies in patients presenting to the emergency department
De Lavallaz, J. Du Fay, Badertscher, P., Nestelberger, T., Cullen, L., Than, M., Miro, O., Martin-Sanchez, J., Morawiec, B., Christ, M., Di Somma, S., Peacock, F., Reichlin, T., Osswald, S. and Mueller, C. (2017). 24-hour patterning of different syncope etiologies in patients presenting to the emergency department. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.
2017
Conference Publication
Diagnostic accuracy of cardiovascular risk factors for an acute coronary syndrome
Gimenez, M. Rubini, Cullen, L., Than, M., Greenslade, J., Twerenbold, R., Boeddinghaus, J., Nestelberger, T., Wildi, K., Badertscher, P., Pickering, J. and Mueller, C. (2017). Diagnostic accuracy of cardiovascular risk factors for an acute coronary syndrome. OXFORD: OXFORD UNIV PRESS.
2017
Journal Article
A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study
Papendick, Cynthia, Blyth, Andrew, Seshadri, A., Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise, Quinn, Stephen, Karnon, Jon, Chuang, Anthony, Nelson, Adam J., Horsfall, Matthew, Morton, Erin and Chew, Derek P. (2017). A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study. American Heart Journal, 190, 25-33. doi: 10.1016/j.ahj.2017.05.004
2017
Conference Publication
Pro-hormones in the early diagnosis of cardiac syncope
Badertscher, P., Nestelberg, T., De Lavallaz, J. Du Fay, Than, M., Morawiec, B., Miro, O., Martin-Sanchez, F. J., Cullen, L., Christ, M., Di Somma, S., Peacock, F., Osswald, S., Reichlin, T. and Mueller, C. (2017). Pro-hormones in the early diagnosis of cardiac syncope. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.
2017
Conference Publication
Natural history of syncope: insights from the BASEL IX study
Badertscher, P., Nestelberger, T., De Lavallaz, J. Du Fay, Than, M., Cullen, L., Miro, O., Martin-Sanchez, F. J., Morawiec, B., Christ, M., Di Somma, S., Peacock, F., Osswald, S., Reichlin, T. and Mueller, C. (2017). Natural history of syncope: insights from the BASEL IX study. Congress of the European-Society-of-Cardiology (ESC), Barcelona Spain, Aug 26-30, 2017. OXFORD: OXFORD UNIV PRESS.
2017
Journal Article
Comparing the no objective testing rule to the HEART pathway
Greenslade, Jaimi and Cullen, Louise (2017). Comparing the no objective testing rule to the HEART pathway. Academic Emergency Medicine, 24 (9), 1169-1170. doi: 10.1111/acem.13240
2017
Journal Article
Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm
Wildi, Karin, Cullen, Louise, Twerenbold, Raphael, Greenslade, Jaimi H., Parsonage, William, Boeddinghaus, Jasper, Nestelberger, Thomas, Sabti, Zaid, Rubini-Gimenez, Maria, Puelacher, Christian, Cupa, Janosch, Schumacher, Lukas, Badertscher, Patrick, Grimm, Karin, Kozhuharov, Nikola, Stelzig, Claudia, Freese, Michael, Rentsch, Katharina, Lohrmann, Jens, Kloos, Wanda, Buser, Andreas, Reichlin, Tobias, Pickering, John W., Than, Martin and Mueller, Christian (2017). Direct comparison of 2 rule-out strategies for acute myocardial infarction: 2-h accelerated diagnostic protocol vs 2-h algorithm. Clinical Chemistry, 63 (7), 1227-1236. doi: 10.1373/clinchem.2016.268359
2017
Journal Article
The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis
Jülicher, Paul, Greenslade, Jaimi H, Parsonage, William A and Cullen, Louise (2017). The organisational value of diagnostic strategies using high-sensitivity troponin for patients with possible acute coronary syndromes: a trial-based cost-effectiveness analysis. BMJ Open, 7 (6) e013653, e013653. doi: 10.1136/bmjopen-2016-013653
2017
Journal Article
Rational clinical evaluation of suspected acute coronary syndromes: The value of more information
Hancock, David G., Chuang, Ming-Yu Anthony, Bystrom, Rebecca, Halabi, Amera, Jones, Rachel, Horsfall, Matthew, Cullen, Louise, Parsonage, William A. and Chew, Derek P. (2017). Rational clinical evaluation of suspected acute coronary syndromes: The value of more information. Emergency Medicine Australasia, 29 (6), 664-671. doi: 10.1111/1742-6723.12819
2017
Journal Article
European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department
Miro, Oscar, Peacock, Frank W., McMurray, John J., Bueno, Hector, Christ, Michael, Maisel, Alan S., Cullen, Louise, Cowie, Martin R., Di Somma, Salvatore, Martin Sanchez, Francisco J., Platz, Elke, Masip, Josep, Zeymer, Uwe, Vrints, Christiaan, Price, Susanna, Mebazaa, Alexander and Mueller, Christian (2017). European Society of Cardiology - acute cardiovascular care association position paper on safe discharge of acute heart failure patients from the emergency department. European Heart Journal-Acute Cardiovascular Care, 6 (4), 311-320. doi: 10.1177/2048872616633853
2017
Journal Article
Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis
Pickering, John W., Than, Martin P., Cullen, Louise, Aldous, Sally, Ter Avest, Ewoud, Body, Richard, Carlton, Edward W., Collinson, Paul, Dupuy, Anne Marie, Ekelund, Ulf, Eggers, Kai M., Florkowski, Christopher M., Freund, Yonathan, George, Peter, Goodacre, Steve, Greenslade, Jaimi H., Jaffe, Allan S., Lord, Sarah J., Mokhtari, Arash, Mueller, Christian, Munro, Andrew, Mustapha, Sebbane, Parsonage, William, Peacock, W. Frank, Pemberton, Christopher, Richards, A. Mark, Sanchis, Juan, Staub, Lukas P., Troughton, Richard ... Young, Joanna (2017). Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac Troponin T measurement below the limit of detection: a collaborative meta-analysis. Annals of Internal Medicine, 166 (10), 715-724. doi: 10.7326/M16-2562
2017
Journal Article
Echocardiography and lung ultrasonography for the assessment and management of acute heart failure
Price, Susanna, for the Acute Heart Failure Study Group of the European Society of Cardiology Acute Cardiovascular Care Association, Platz, Elke, Cullen, Louise, Tavazzi, Guido, Christ, Michael, Cowie, Martin R., Maisel, Alan S., Masip, Josep, Miro, Oscar, McMurray, John J., Peacock, W. Frank, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Bueno, Hector, Zeymer, Uwe and Mueller, Christian (2017). Echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nature Reviews Cardiology, 14 (7), 427-440. doi: 10.1038/nrcardio.2017.56
2017
Journal Article
Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction"
Than, Martin P., Pickering, John W., Cullen, Louise and Kavsak, Peter A. (2017). Response by Than et al to Letter Regarding Article, "assessment of the European Society of Cardiology 0-Hour/1-Hour Algorithm to Rule-Out and Rule-In Acute Myocardial Infarction". Circulation, 135 (16), e923-e924. doi: 10.1161/CIRCULATIONAHA.117.027479
2017
Journal Article
Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study
Lavery, Tim, Greenslade, Jaimi H., Parsonage, William A., Hawkins, Tracey, Dalton, Emily, Hammett, Christopher and Cullen, Louise (2017). Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study. Emergency Medicine Australasia, 29 (2), 210-216. doi: 10.1111/1742-6723.12735
2017
Journal Article
Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI
Tan, Jack Wei Chieh, Lam, Carolyn S. P., Kasim, Sazzli Shahlan, Aw, Tar Choon, Abanilla, Joel M., Chang, Wei-Ting, Dang, Van Phuoc, Iboleon-Dy, Maria, Mumpuni, Sari Sri, Phommintikul, Arintaya, Ta, Manh Cuong, Topipat, Punkiat, Yiu, Kai Hang and Cullen, Louise (2017). Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI. Heart Asia, 9 (1) e000357, 81-87. doi: 10.1136/heartasia-2016-010818
2017
Journal Article
The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain
Knowlman, Thomas, Greenslade, Jaimi H., Parsonage, William, Hawkins, Tracey, Ruane, Lorcan, Martin, Paul, Prasad, Sandhir, Lancini, Daniel and Cullen, Louise (2017). The association of electrocardiographic abnormalities and acute coronary syndrome in emergency patients with chest pain. Academic Emergency Medicine, 24 (3), 344-352. doi: 10.1111/acem.13123
2017
Journal Article
The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol
Huis in ’t Veld, Maite Anna, Cullen, Louise, Mahler, Simon A., Backus, Barbra E., Dezman, Zachary D.W. and Mattu, Amal (2017). The Fast and the Furious: Low-Risk Chest Pain and the Rapid Rule-Out Protocol. Western Journal of Emergency Medicine, 18 (3), 474-478. doi: 10.5811/westjem.2016.12.32676
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study
Principal Advisor
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Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
Completed supervision
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2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
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2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
Enquiries
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