Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2020
Journal Article
Risk stratification scores for patients with acute heart failure in the Emergency Department: A systematic review
Miró, Òscar, Rossello, Xavier, Platz, Elke, Masip, Josep, Gualandro, Danielle M., Peacock, W. Frank, Price, Susanna, Cullen, Louise, DiSomma, Salvatore, de Oliveira Jr, Mucio Tavares, McMurray, John J. V., Martín-Sánchez, Francisco J., Maisel, Alan S., Vrints, Christiaan, Cowie, Martin R., Bueno, Héctor, Mebazaa, Alexandre, Mueller, Christian and The Study Group on Acute Heart Failure of the Acute Cardiovascular Care Association of the European Society of Cardiology (2020). Risk stratification scores for patients with acute heart failure in the Emergency Department: A systematic review. European Heart Journal. Acute Cardiovascular Care, 9 (5), 375-398. doi: 10.1177/2048872620930889
2020
Journal Article
CSANZ Position Statement on the Evaluation of Patients Presenting With Suspected Acute Coronary Syndromes During the COVID-19 Pandemic
Parsonage, William A., Cullen, Louise, Brieger, David, Hillis, Graham S., Nasis, Arthur, Dwyer, Nathan, Wahi, Sudhir, Lo, Sidney, Than, Martin, Kerr, Andrew, Devlin, Gerard and Chew, Derek K. (2020). CSANZ Position Statement on the Evaluation of Patients Presenting With Suspected Acute Coronary Syndromes During the COVID-19 Pandemic. Heart, Lung and Circulation, 29 (7), e105-e110. doi: 10.1016/j.hlc.2020.05.003
2020
Journal Article
Widespread introduction of a high-sensitivity troponin assay: assessing the impact on patients and health services
Greenslade, Jaimi H., Parsonage, William, Foran, Laura, McCormack, Louise, Ashover, Sarah, Milburn, Tanya, Berndt, Sara, Than, Martin, Brain, David and Cullen, Louise (2020). Widespread introduction of a high-sensitivity troponin assay: assessing the impact on patients and health services. Journal of Clinical Medicine, 9 (6) 1883, 1-12. doi: 10.3390/jcm9061883
2020
Journal Article
Application of the fourth universal definition of myocardial infarction in clinical practice
Mair, Johannes, Cullen, Louise, Giannitsis, Evangelos, Hammarsten, Ola, Huber, Kurt, Jaffe, Allan, Mills, Nicholas, Möckel, Martin, Müller, Christian, Thygesen, Kristian and Lindahl, Bertil (2020). Application of the fourth universal definition of myocardial infarction in clinical practice. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 25 (4), 322-330. doi: 10.1080/1354750X.2020.1764108
2020
Journal Article
Examining the translational success of an initiative to accelerate the assessment of chest pain for patients in an Australian emergency department: A pre-post study
Greenslade, Jaimi H., Ho, Ariel, Hawkins, Tracey, Parsonage, William, Crilly, Julia and Cullen, Louise (2020). Examining the translational success of an initiative to accelerate the assessment of chest pain for patients in an Australian emergency department: A pre-post study. BMC Health Services Research, 20 (1) 419, 1-9. doi: 10.1186/s12913-020-05296-1
2020
Journal Article
Facilitators and barriers for emergency department clinicians using a rapid chest pain assessment protocol: qualitative interview research
Crilly, Julia, Greenslade, Jaimi H., Berndt, Sara, Hawkins, Tracey and Cullen, Louise (2020). Facilitators and barriers for emergency department clinicians using a rapid chest pain assessment protocol: qualitative interview research. BMC Health Services Research, 20 (1) 74, 1-11. doi: 10.1186/s12913-020-4923-2
2019
Journal Article
Factors influencing physician risk estimates for acute cardiac events in emergency patients with suspected acute coronary syndrome
Greenslade, Jaimi H., Sieben, Nicolas, Parsonage, William A., Knowlman, Thomas, Ruane, Lorcan, Than, Martin, Pickering, John W., Hawkins, Tracey and Cullen, Louise (2019). Factors influencing physician risk estimates for acute cardiac events in emergency patients with suspected acute coronary syndrome. Emergency Medicine Journal, 37 (1), 2-7. doi: 10.1136/emermed-2019-208916
2019
Journal Article
A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT)
Chew, Derek P., Lambrakis, Kristina, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, Karnon, Jonathan, Chuang, Anthony, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, French, John K. and Papendick, Cynthia (2019). A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT). Circulation, 140 (19), 1543-1556. doi: 10.1161/CIRCULATIONAHA.119.042891
2019
Journal Article
Two-hour algorithm for rapid triage of suspected acute myocardial infarction using a high-sensitivity cardiac troponin I assay
Nestelberger, Thomas, Boeddinghaus, Jasper, Greenslade, Jaimi, Parsonage, William A., Than, Martin, Wussler, Desiree, Lopez-Ayala, Pedro, Zimmermann, Tobias, Meier, Mario, Troester, Valentina, Badertscher, Patrick, Koechlin, Luca, Wildi, Karin, Anwar, Mahnoor, Freese, Michael, Keller, Dagmar, Reichlin, Tobias, Twerenbold, Raphael, Cullen, Louise and Mueller, Christian (2019). Two-hour algorithm for rapid triage of suspected acute myocardial infarction using a high-sensitivity cardiac troponin I assay. Clinical Chemistry, 65 (11), 1437-1447. doi: 10.1373/clinchem.2019.305193
2019
Conference Publication
Two-hour algorithm for early diagnosis of acute myocardial infarction using a novel high-sensitivity cardiac troponin I assay
Nestelberger, T., Boeddinghaus, J., Greenslade, J., Cullen, L., Parsonage, W., Troester, V., Koechlin, L., Rubini, M., Badertscher, P., Puelacher, C., Twerenbold, R. and Mueller, C. (2019). Two-hour algorithm for early diagnosis of acute myocardial infarction using a novel high-sensitivity cardiac troponin I assay. Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, Paris France, Aug 31-Sep 04, 2019. OXFORD: OXFORD UNIV PRESS.
2019
Journal Article
Diagnosis of acute myocardial infarction in the presence of left bundle branch block
Nestelberger, Thomas, Cullen, Louise, Lindahl, Bertil, Reichlin, Tobias, Greenslade, Jaimi H., Giannitsis, Evangelos, Christ, Michael, Morawiec, Beata, Miro, Oscar, Martín-Sánchez, Francisco Javier, Wussler, Desiree Nadine, Koechlin, Luca, Twerenbold, Raphael, Parsonage, William, Boeddinghaus, Jasper, Rubini Gimenez, Maria, Puelacher, Christian, Wildi, Karin, Buerge, Tobias, Badertscher, Patrick, DuFaydeLavallaz, Jeanne, Strebel, Ivo, Croton, Lukas, Bendig, Garnet, Osswald, Stefan, Pickering, John William, Than, Martin, Mueller, Christian and APACE, ADAPT and TRAPID-AMI Investigators (2019). Diagnosis of acute myocardial infarction in the presence of left bundle branch block. Heart, 105 (20), 1559-1567. doi: 10.1136/heartjnl-2018-314673
2019
Conference Publication
Rapid rule-out of myocardial infarction with a novel high precision point-of-care troponin assay appears safe and effective
Aldous, S., Pickering, J., Young, J., George, P., Watson, A., Troughton, R., Pemberton, C., Richards, M., Cullen, L. and Than, M. (2019). Rapid rule-out of myocardial infarction with a novel high precision point-of-care troponin assay appears safe and effective. Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, Paris France, Aug 31-Sep 04, 2019. OXFORD: OXFORD UNIV PRESS.
2019
Conference Publication
Diagnosis of acute myocardial infarction in the presence of left bundle-branch block
Nestelberger, T., Cullen, L., Lindahl, B., Reichlin, T., Greenslade, J., Giannitsis, E., Morawiec, B., Koechlin, L., Twerenbold, R., Boeddinghaus, J., Rubini, M., Osswald, S., Pickering, J., Than, M. and Mueller, C. (2019). Diagnosis of acute myocardial infarction in the presence of left bundle-branch block. Congress of the European-Society-of-Cardiology (ESC) / World Congress of Cardiology, Paris France, Aug 31-Sep 04, 2019. OXFORD: OXFORD UNIV PRESS.
2019
Journal Article
Letter by Egerton-Warburton et al Regarding Article, “Duration of Electrocardiographic Monitoring of Emergency Department Patients With Syncope”
Egerton-Warburton, Diana, Maclean, Patrick and Cullen, Louise (2019). Letter by Egerton-Warburton et al Regarding Article, “Duration of Electrocardiographic Monitoring of Emergency Department Patients With Syncope”. Circulation, 140 (12). doi: 10.1161/circulationaha.119.040717
2019
Journal Article
Machine Learning to Predict the Likelihood of Acute Myocardial Infarction
Than, Martin P., Pickering, John W., Sandoval, Yader, Shah, Anoop S.V., Tsanas, Athanasios, Apple, Fred S., Blankenberg, Stefan, Cullen, Louise, Mueller, Christian, Neumann, Johannes T., Twerenbold, Raphael, Westermann, Dirk, Beshiri, Agim, Mills, Nicholas L., George, Peter M., Richards, A Mark, Troughton, Richard W., Aldous, Sally J., Chapman, Andrew R., Anand, Atul, Greenslade, Jaimi, Parsonage, William, Boeddinghaus, Jasper, Wildi, Karin, Nestelberger, Thomas, Badertscher, Patrick, Du, Shaoqing, Huang, Janel, Smith, Stephen W. ... On behalf of the MI Collaborative (2019). Machine Learning to Predict the Likelihood of Acute Myocardial Infarction. Circulation, 140 (11), 899-909. doi: 10.1161/circulationaha.119.041980
2019
Journal Article
Prevalence of pulmonary embolism in patients with syncope
Badertscher, Patrick, du Fay de Lavallaz, Jeanne, Hammerer-Lercher, Angelika, Nestelberger, Thomas, Zimmermann, Tobias, Geiger, Marc, Imahorn, Orell, Miró, Òscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Costabel, Juan Pablo, Walter, Joan, Boeddinghaus, Jasper, Twerenbold, Raphael, Méndez, Adriana, Gospodinov, Boris, Puelacher, Christian, Wussler, Desiree, Koechlin, Luca, Kawecki, Damian, Geigy, Nicolas, Strebel, Ivo, Lohrmann, Jens ... Osswald, Stefan (2019). Prevalence of pulmonary embolism in patients with syncope. Journal of the American College of Cardiology, 74 (6), 744-754. doi: 10.1016/j.jacc.2019.06.020
2019
Journal Article
Application of high-sensitivity troponin in suspected myocardial infarction
Neumann, Johannes T., Twerenbold, Raphael, Ojeda, Francisco, Sörensen, Nils A., Chapman, Andrew R., Shah, Anoop S.V., Anand, Atul, Boeddinghaus, Jasper, Nestelberger, Thomas, Badertscher, Patrick, Mokhtari, Arash, Pickering, John W., Troughton, Richard W., Greenslade, Jaimi, Parsonage, William, Mueller-Hennessen, Matthias, Gori, Tommaso, Jernberg, Tomas, Morris, Niall, Liebetrau, Christoph, Hamm, Christian, Katus, Hugo A., Münzel, Thomas, Landmesser, Ulf, Salomaa, Veikko, Iacoviello, Licia, Ferrario, Marco M., Giampaoli, Simona, Kee, Frank ... Blankenberg, Stefan (2019). Application of high-sensitivity troponin in suspected myocardial infarction. New England Journal of Medicine, 380 (26), 2529-2540. doi: 10.1056/nejmoa1803377
2019
Journal Article
Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure
Platz, Elke, Jhund, Pardeep S., Girerd, Nicolas, Pivetta, Emanuele, McMurray, John J.V., Peacock, W. Frank, Masip, Josep, Martin‐Sanchez, Francisco Javier, Miró, Òscar, Price, Susanna, Cullen, Louise, Maisel, Alan S., Vrints, Christiaan, Cowie, Martin R., DiSomma, Salvatore, Bueno, Hector, Mebazaa, Alexandre, Gualandro, Danielle M., Tavares, Mucio, Metra, Marco, Coats, Andrew J.S., Ruschitzka, Frank, Seferovic, Petar M., Mueller, Christian and on behalf of the Study Group on Acute Heart Failure of the Acute Cardiovascular Care Association and the Heart Failure Association of the European Society of Cardiology (2019). Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure. European Journal of Heart Failure, 21 (7), 844-851. doi: 10.1002/ejhf.1499
2019
Journal Article
B-Type Natriuretic Peptides and Cardiac Troponins for Diagnosis and Risk-Stratification of Syncope
du Fay de Lavallaz, Jeanne, Badertscher, Patrick, Nestelberger, Thomas, Zimmermann, Tobias, Miró, Òscar, Salgado, Emilio, Christ, Michael, Geigy, Nicolas, Cullen, Louise, Than, Martin, Javier Martin-Sanchez, F., Di Somma, Salvatore, Frank Peacock, W., Morawiec, Beata, Walter, Joan, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, Boeddinghaus, Jasper, Koechlin, Luca, Strebel, Ivo, Keller, Dagmar I., Lohrmann, Jens, Michou, Eleni, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola ... For the BASEL IX Investigators (2019). B-Type Natriuretic Peptides and Cardiac Troponins for Diagnosis and Risk-Stratification of Syncope. Circulation, 139 (21), 2403-2418. doi: 10.1161/circulationaha.118.038358
2019
Journal Article
Recognizing the potential for overdiagnosis: are high-sensitivity cardiac troponin assays an example?
Bell, Katy J. L., Doust, Jenny, Glasziou, Paul, Cullen, Louise, Harris, Ian A., Smith, Leon, Buchbinder, Rachelle and Barratt, Alexandra (2019). Recognizing the potential for overdiagnosis: are high-sensitivity cardiac troponin assays an example?. Annals of Internal Medicine, 170 (4), 259-+. doi: 10.7326/M18-2645
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study
Principal Advisor
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Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
Completed supervision
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2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
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2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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