Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

268 works between 2004 and 2025
All (268) Journal Article (232) Conference Publication (36)

61 - 80 of 268 works

2021

Journal Article

Chest pain assessment: what is our endgame?

Cullen, Louise, Greenslade, Jaimi and Parsonage, William (2021). Chest pain assessment: what is our endgame?. Clinical Chemistry, 68 (2), 261-263. doi: 10.1093/clinchem/hvab246

Chest pain assessment: what is our endgame?

2021

Journal Article

Biomarker-based risk scores in atrial fibrillation

Hijazi, Ziad, Mills, Nicholas L., Mueller, Christian, Giannitsis, Evangelos, Jaffe, Allan S., Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Lindahl, Bertil (2021). Biomarker-based risk scores in atrial fibrillation. European Heart Journal: Acute Cardiovascular Care, 10 (9), 1084-1085. doi: 10.1093/ehjacc/zuab088

Biomarker-based risk scores in atrial fibrillation

2021

Journal Article

Applying a framework to assess the impact of cardiovascular outcomes improvement research

Sarkies, Mitchell N., Robinson, Suzanne, Briffa, Tom, Duffy, Stephen J., Nelson, Mark, Beltrame, John, Cullen, Louise, Chew, Derek, Smith, Julian, Brieger, David, Macdonald, Peter, Liew, Danny and Reid, Chris (2021). Applying a framework to assess the impact of cardiovascular outcomes improvement research. Health Research Policy and Systems, 19 (1) 67, 1-12. doi: 10.1186/s12961-021-00710-4

Applying a framework to assess the impact of cardiovascular outcomes improvement research

2021

Journal Article

Evaluation of the Atellica TnIH cardiac troponin i assay and assessment of biological equivalence

Pretorius, Carel J., Parsonage, William, Cullen, Louise W., Wilgen, Urs, De Waal, Elzahn, Klingberg, Sandra, Dimeski, Goce, White, Rob, Greenslade, Jaimi and Ungerer, Jacobus P.J. (2021). Evaluation of the Atellica TnIH cardiac troponin i assay and assessment of biological equivalence. Clinical Chemistry and Laboratory Medicine, 60 (2) 0991, 283-290. doi: 10.1515/cclm-2021-0991

Evaluation of the Atellica TnIH cardiac troponin i assay and assessment of biological equivalence

2021

Conference Publication

Cost Effectiveness of a 1-Hour High-Sensitivity Troponin-t Protocol in Suspected Acute Coronary Syndrome: A Trial-Based Analysis of the Rapid-tnt Randomised Trial

Chuang, Anthony, Gnanamanickam, Emmanuel, Lambrakis, Kristina, Horsfall, Matthew, Karnon, Jonathan, Blyth, Andrew, Seshadri, Anil, Nguyen, Mau, Briffa, Tom G., Cullen, Louise, Quinn, Stephen, French, John K. and Chew, Derek P. (2021). Cost Effectiveness of a 1-Hour High-Sensitivity Troponin-t Protocol in Suspected Acute Coronary Syndrome: A Trial-Based Analysis of the Rapid-tnt Randomised Trial. Annual Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, Boston Ma, Nov 12-15, 2021. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Cost Effectiveness of a 1-Hour High-Sensitivity Troponin-t Protocol in Suspected Acute Coronary Syndrome: A Trial-Based Analysis of the Rapid-tnt Randomised Trial

2021

Journal Article

Potential impact of a novel pathway for suspected myocardial infarction utilising a new high-sensitivity cardiac troponin I assay

Meek, Rob, Cullen, Louise, Lu, Zhong Xian, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2021). Potential impact of a novel pathway for suspected myocardial infarction utilising a new high-sensitivity cardiac troponin I assay. Emergency Medicine Journal, 39 (11), 1-6. doi: 10.1136/emermed-2020-210812

Potential impact of a novel pathway for suspected myocardial infarction utilising a new high-sensitivity cardiac troponin I assay

2021

Journal Article

Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain

Sharma, Sweekriti, Traeger, Adrian C., Tcharkhedian, Elise, Middleton, Paul M., Cullen, Louise and Maher, Chris G. (2021). Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain. International Journal for Quality in Health Care, 33 (4) mzab129, 1-11. doi: 10.1093/intqhc/mzab129

Effect of a waiting room communication strategy on imaging rates and awareness of public health messages for low back pain

2021

Journal Article

Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria

Dodd, Kenneth W., Zvosec, Deborah L., Hart, Michael A., Glass, George, Bannister, Laura E., Body, Richard M., Boggust, Brett A., Brady, William J., Chang, Anna M., Cullen, Louise, Gómez-Vicente, Rafael, Huis in ‘t Veld, Maite A., Karim, Rehan M., Meyers, H. Pendell, Miranda, David F., Mitchell, Gary J., Reynard, Charles, Rice, Clifford, Salverda, Bayert J., Stellpflug, Samuel J., Tolia, Vaishal M., Walsh, Brooks M., White, Jennifer L., Smith, Stephen W., Smith, Stephen W., Dodd, Kenneth W., Zvosec, Deborah L., Karim, Rehan M., Hart, Michael A. ... on behalf of the PERFECT study investigators (2021). Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria. Annals of Emergency Medicine, 78 (4), 517-529. doi: 10.1016/j.annemergmed.2021.03.036

Electrocardiographic Diagnosis of Acute Coronary Occlusion Myocardial Infarction in Ventricular Paced Rhythm Using the Modified Sgarbossa Criteria

2021

Journal Article

Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle‐Branch Block

Nestelberger, Thomas, Boeddinghaus, Jasper, Lopez Ayala, Pedro, Gehrke, Juliane, Twerenbold, Raphael, Cullen, Louise, Mueller, Christian, Strebel, Ivo, Prepoudis, Alexandra, Gualandro, Danielle M., Puelacher, Christian, du Fay Lavallaz, Jeanne, Frey, Simon Martin, Ratmann, Paul David, Arslani, Ketina, Walter, Joan Elias, Freese, Michael, Shrestha, Samyut, Belkin, Maria, Koechlin, Luca, Hillinger, Petra, Potlukova, Eliska, Rentsch, Katharina, Mitrovic, Sandra, Kawecki, Damian, Morawiec, Beata, Munzk, Piotr, Geigy, Nicolas, Reichlin, Tobias ... on behalf of the APACE, ADAPT, TRAPID- AMI Investigators (2021). Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle‐Branch Block. Journal of the American Heart Association, 10 (18) e021262. doi: 10.1161/jaha.121.021262

Utility of Echocardiography in Patients With Suspected Acute Myocardial Infarction and Left Bundle‐Branch Block

2021

Journal Article

Is a nudge all we need to promote deliberate clinical inertia and thoughtful clinical decision making?

Foster, Mieke, Egerton‐Warburton, Diana, Cullen, Louise, Fatovich, Daniel M. and Keijzers, Gerben (2021). Is a nudge all we need to promote deliberate clinical inertia and thoughtful clinical decision making?. Emergency Medicine Australasia, 33 (4), 748-752. doi: 10.1111/1742-6723.13782

Is a nudge all we need to promote deliberate clinical inertia and thoughtful clinical decision making?

2021

Journal Article

Classification performance of clinical risk scoring in suspected acute coronary syndrome beyond a rule-out troponin profile

Khan, Ehsan, Lambrakis, Kristina, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, Horsfall, Matthew, Morton, Erin, French, John K., Papendick, Cynthia, Nelson, Adam J. and Chew, Derek P. (2021). Classification performance of clinical risk scoring in suspected acute coronary syndrome beyond a rule-out troponin profile. European Heart Journal. Acute Cardiovascular Care, 10 (9), 1038-1047. doi: 10.1093/ehjacc/zuab040

Classification performance of clinical risk scoring in suspected acute coronary syndrome beyond a rule-out troponin profile

2021

Journal Article

A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT) (vol 140, pg 1543, 2019)

Chew, Derek P., Lambrakis, Kristina, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J. R., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, Karnon, Jonathan, Chuang, Anthony, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, French, John K. and Papendick, Cynthia (2021). A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT) (vol 140, pg 1543, 2019). Circulation, 143 (25), E1118-E1118. doi: 10.1161/CIR.0000000000000994

A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT) (vol 140, pg 1543, 2019)

2021

Journal Article

ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: a fond farewell at the retirement of CKMB

Jaffe, Allan S, Lindahl, Bertil, Giannitsis, Evangelos, Mueller, Christian, Cullen, Louise, Hammarsten, Ola, Mockel, Martin, Mair, Johannes, Krychtiuk, Konstantin A, Huber, Kurt, Mills, Nicholas L and Thygesen, Kristian (2021). ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: a fond farewell at the retirement of CKMB. European Heart Journal, 42 (23), 2260-2264. doi: 10.1093/eurheartj/ehaa1079

ESC Study Group on Cardiac Biomarkers of the Association for Acute CardioVascular Care: a fond farewell at the retirement of CKMB

2021

Journal Article

Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS

Lambrakis, Kristina, Papendick, Cynthia, French, John K., Quinn, Stephen, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J.R., Chuang, Anthony, Khan, Ehsan, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, Karnon, Jonathan, Briffa, Tom, Cullen, Louise A. and Chew, Derek P. (2021). Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS. Circulation, 144 (2), 113-125. doi: 10.1161/CIRCULATIONAHA.121.055009

Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS

2021

Conference Publication

EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN

Sharma, Sweekriti, Traeger, Adrian, Tcharkhedian, Elise, Middleton, Paul, Cullen, Louise and Maher, Chris (2021). EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN. HOBOKEN: WILEY.

EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN

2021

Journal Article

Cardiovascular biomarkers in patients with COVID-19

Mueller, Christian, Giannitsis, Evangelos, Jaffe, Allan S., Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Mills, Nicholas L., Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Lindahl, Bertil and ESC Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association (2021). Cardiovascular biomarkers in patients with COVID-19. European Heart Journal. Acute Cardiovascular Care, 10 (3), 310-319. doi: 10.1093/ehjacc/zuab009

Cardiovascular biomarkers in patients with COVID-19

2021

Journal Article

Development of an electrocardiogram-based risk calculator for a cardiac cause of syncope

Zimmermann, Tobias, du Fay de Lavallaz, Jeanne, Walter, Joan Elias, Strebel, Ivo, Nestelberger, Thomas, Joray, Lydia, Badertscher, Patrick, Flores, Dayana, Widmer, Velina, Geigy, Nicolas, Miro, Oscar, Salgado, Emilio, Christ, Michael, Cullen, Louise, Than, Martin, Martín-Sánchez, Francisco Javier, Di Somma, Salvatore, Peacock, W Frank, Keller, Dagmar, Costabel, Juan Pablo, Wussler, Desiree Nadine, Kawecki, Damian, Lohrmann, Jens, Gualandro, Danielle Menosi, Kuehne, Michael, Reichlin, Tobias, Sun, Benjamin and Mueller, Christian (2021). Development of an electrocardiogram-based risk calculator for a cardiac cause of syncope. Heart, 107 (22), 1796-1804. doi: 10.1136/heartjnl-2020-318430

Development of an electrocardiogram-based risk calculator for a cardiac cause of syncope

2020

Conference Publication

Utility of echocardiography in patients with suspected acute myocardial infarction in the presence of left bundle-branch block

Ratmann, P. D., Nestelberger, T., Cullen, L., Lindahl, B., Boeddinghaus, J., Rubini, M., Ayala, P. Lopez, Than, M., Greenslade, J. and Mueller, C. (2020). Utility of echocardiography in patients with suspected acute myocardial infarction in the presence of left bundle-branch block. European-Society-of-Cardiology (ESC) Congress, Electr Network, Aug 29-Sep 01, 2020. OXFORD: OXFORD UNIV PRESS.

Utility of echocardiography in patients with suspected acute myocardial infarction in the presence of left bundle-branch block

2020

Journal Article

Incidence, characteristics, determinants, and prognostic impact of recurrent syncope

Zimmermann, Tobias, du Fay de Lavallaz, Jeanne, Nestelberger, Thomas, Gualandro, Danielle M., Strebel, Ivo, Badertscher, Patrick, Lopez-Ayala, Pedro, Widmer, Velina, Freese, Michael, Miró, Òscar, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W Frank, Keller, Dagmar I., Boeddinghaus, Jasper, Twerenbold, Raphael, Wussler, Desiree, Koechlin, Luca, Walter, Joan E., Bürgler, Franz, Geigy, Nicolas, Kühne, Michael, Reichlin, Tobias, Lohrmann, Jens and Mueller, Christian (2020). Incidence, characteristics, determinants, and prognostic impact of recurrent syncope. Europace, 22 (12), 1885-1895. doi: 10.1093/europace/euaa227

Incidence, characteristics, determinants, and prognostic impact of recurrent syncope

2020

Journal Article

Using Sex‐specific Cutoffs for High‐sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction

Peacock, W. Frank, Baumann, Brigitte M., Rivers, E. Joy, Davis, Thomas E., Handy, Beverly, Jones, Christopher W., Hollander, Judd E., Limkakeng, Alexander T., Mehrotra, Abhi, Than, Martin, Cullen, Louise, Ziegler, André and Dinkel‐Keuthage, Carina (2020). Using Sex‐specific Cutoffs for High‐sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction. Academic Emergency Medicine, 28 (4), 463-466. doi: 10.1111/acem.14098

Using Sex‐specific Cutoffs for High‐sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction

Current funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant

Past funding

  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study

    Principal Advisor

  • Doctor Philosophy

    Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study

    Principal Advisor

Completed supervision

Enquiries

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