Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

268 works between 2004 and 2025
All (268) Journal Article (232) Conference Publication (36)

41 - 60 of 268 works

2022

Journal Article

Care models for acute chest pain that improve outcomes and efficiency: JACC state-of-the-art review

Dawson, Luke P., Smith, Karen, Cullen, Louise, Nehme, Ziad, Lefkovits, Jeffrey, Taylor, Andrew J. and Stub, Dion (2022). Care models for acute chest pain that improve outcomes and efficiency: JACC state-of-the-art review. Journal of the American College of Cardiology, 79 (23), 2333-2348. doi: 10.1016/j.jacc.2022.03.380

Care models for acute chest pain that improve outcomes and efficiency: JACC state-of-the-art review

2022

Journal Article

Development and validation of a comprehensive early risk prediction model for patients with undifferentiated acute chest pain

Dawson, Luke P., Andrew, Emily, Nehme, Ziad, Bloom, Jason, Liew, Danny, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew J., Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2022). Development and validation of a comprehensive early risk prediction model for patients with undifferentiated acute chest pain. IJC Heart and Vasculature, 40 101043. doi: 10.1016/j.ijcha.2022.101043

Development and validation of a comprehensive early risk prediction model for patients with undifferentiated acute chest pain

2022

Journal Article

International validation of the Canadian Syncope Risk Score: a cohort study

Zimmermann, Tobias, de Lavallaz, Jeanne du Fay, Nestelberger, Thomas, Gualandro, Danielle M., Lopez-Ayala, Pedro, Badertscher, Patrick, Widmer, Velina, Shrestha, Samyut, Strebel, Ivo, Glarner, Noemi, Diebold, Matthias, Miró, Òscar, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F. Javier, Di Somma, Salvatore, Peacock, W. Frank, Keller, Dagmar I., Bilici, Murat, Costabel, Juan Pablo, Kühne, Michael, Breidthardt, Tobias, Thiruganasambandamoorthy, Venkatesh, Mueller, Christian and BASEL IX Investigators† (2022). International validation of the Canadian Syncope Risk Score: a cohort study. Annals of Internal Medicine, 175 (6), 783-794. doi: 10.7326/m21-2313

International validation of the Canadian Syncope Risk Score: a cohort study

2022

Journal Article

Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease

Rajkumar, Christopher A., Wereski, Ryan, Parsonage, William, Cullen, Louise, Khamis, Ramzi, Foley, Michael, Harrell, Frank E., Shun-Shin, Matthew J., Mills, Nicholas L. and Al-Lamee, Rasha K. (2022). Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease. Journal of the American College of Cardiology, 79 (21), 2185-2187. doi: 10.1016/j.jacc.2022.03.369

Association Between High-Sensitivity Cardiac Troponin, Myocardial Ischemia, and Revascularization in Stable Coronary Artery Disease

2022

Journal Article

Value of single troponin values in the emergency department for excluding acute myocardial infarction in Aboriginal and Torres Strait Islander people

Greenslade, Jaimi H., Berndt, Sara, Stephensen, Laura, Starmer, Katrina, Starmer, Greg, Parsonage, William, Lau, Victor, Drahm‐Butler, Tileah, Davis, Tania, Campbell, Virginia, Stone, Richard, Bonnin, Robert, Ashover, Sarah, Milburn, Tanya, Mowatt, Elizabeth, Proctor, Karlie, Brazzale, Anthony and Cullen, Louise Ann (2022). Value of single troponin values in the emergency department for excluding acute myocardial infarction in Aboriginal and Torres Strait Islander people. Medical Journal of Australia, 217 (1), 48-49. doi: 10.5694/mja2.51544

Value of single troponin values in the emergency department for excluding acute myocardial infarction in Aboriginal and Torres Strait Islander people

2022

Journal Article

The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction–from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC)

Mair, Johannes, Jaffe, Allan, Lindahl, Bertil, Mills, Nicholas, Möckel, Martin, Cullen, Louise, Giannitsis, Evangelos, Hammarsten, Ola, Huber, Kurt, Krychtiuk, Konstantin, Mueller, Christian and Thygesen, Kristian (2022). The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction–from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC). Biomarkers, 27 (5), 407-417. doi: 10.1080/1354750X.2022.2055792

The clinical approach to diagnosing peri-procedural myocardial infarction after percutaneous coronary interventions according to the fourth universal definition of myocardial infarction–from the study group on biomarkers of the European Society of Cardiology (ESC) Association for Acute CardioVascular Care (ACVC)

2022

Journal Article

Use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in the emergency department

Daniels, Lori B, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Jaffe, Allan S., Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Study Group on Biomarkers of the ESC for Acute CardioVascular Care (2022). Use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in the emergency department. European Heart Journal: Acute Cardiovascular Care, 11 (5), 440-441. doi: 10.1093/ehjacc/zuac042

Use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in the emergency department

2022

Journal Article

From little things, big things grow: An exploratory analysis of the national cost of peripheral intravenous catheter insertion in Australian adult emergency care

Morgan, Rachel, Callander, Emily, Cullen, Louise, Walker, Katie, Bumpstead, Suzanne, Hawkins, Tracey, Kuhn, Lisa and Egerton-Warburton, Diana (2022). From little things, big things grow: An exploratory analysis of the national cost of peripheral intravenous catheter insertion in Australian adult emergency care. EMA - Emergency Medicine Australasia, 34 (6), 877-883. doi: 10.1111/1742-6723.14009

From little things, big things grow: An exploratory analysis of the national cost of peripheral intravenous catheter insertion in Australian adult emergency care

2022

Conference Publication

EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN IN THE EMERGENCY DEPARTMENT

Sharma, Sweekriti, Traeger, Adrian, Tcharkhedian, Elise, Middleton, Paul, Cullen, Louise and Maher, Chris (2022). EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN IN THE EMERGENCY DEPARTMENT. HOBOKEN: WILEY.

EFFECT OF A WAITING ROOM COMMUNICATION STRATEGY ON IMAGING RATES AND AWARENESS OF PUBLIC HEALTH MESSAGES FOR LOW BACK PAIN IN THE EMERGENCY DEPARTMENT

2022

Journal Article

The intra-individual variation of cardiac troponin I: the effects of sex, age, climatic season, and time between samples

Koerbin, Gus, Potter, Julia M., Pinto Do Nascimento, Marcela, Cullen, Louise, Scanlan, Samuel L., Woods, Catherine and Hickman, Peter E. (2022). The intra-individual variation of cardiac troponin I: the effects of sex, age, climatic season, and time between samples. Clinical Chemistry and Laboratory Medicine, 60 (7), 1101-1109. doi: 10.1515/cclm-2022-0125

The intra-individual variation of cardiac troponin I: the effects of sex, age, climatic season, and time between samples

2022

Journal Article

What is an acceptable risk of major adverse cardiac event soon after discharge from emergency? the patient’s perspective

Greenslade, Jaimi H, Wilkinson, Sarah, Parsonage, William and Cullen, Louise (2022). What is an acceptable risk of major adverse cardiac event soon after discharge from emergency? the patient’s perspective. Emergency Medicine Journal, 39 (7) 212251, 519-520. doi: 10.1136/emermed-2021-212251

What is an acceptable risk of major adverse cardiac event soon after discharge from emergency? the patient’s perspective

2022

Journal Article

Troponins in myocardial infarction and injury

Potter, Julia M., Hickman, Peter E. and Cullen, Louise (2022). Troponins in myocardial infarction and injury. Australian Prescriber, 45 (2), 53-57. doi: 10.18773/austprescr.2022.006

Troponins in myocardial infarction and injury

2022

Journal Article

How to deal with unexpected cardiac troponin results

Mair, Johannes, Giannitsis, Evangelos, Mills, Nicholas L., Mueller, Christian, Study Group on Biomarkers of the European Society of Cardiology Association for Acute CardioVascular Care, Lindahl, Bertil, Cullen, Louise, Hammarsten, Ola, Huber, Kurt, Jaffe, Allan S., Krychtiuk, Konstantin, Möckel, Martin and Thygesen, Kristian (2022). How to deal with unexpected cardiac troponin results. European Heart Journal: Acute Cardiovascular Care, 11 (4), E1-E3. doi: 10.1093/ehjacc/zuac023

How to deal with unexpected cardiac troponin results

2022

Journal Article

Acute Heart Failure in the 2021 ESC Heart Failure Guidelines: A scientific statement from the Association for Acute CardioVascular Care (ACVC) of the European Society of Cardiology

Masip, Josep, Peacok, W. Frank, Arrigo, Mattia, Rossello, Xavier, Platz, Elke, Cullen, Louise, Mebazaa, Alexandre, Price, Susanna, Bueno, Hcrossed D Sign©ctor, Somma, Salvatore Di, Tavares, Mucio, Cowie, Martin R, Maisel, Alan, Mueller, Christian and Miro, Òsar (2022). Acute Heart Failure in the 2021 ESC Heart Failure Guidelines: A scientific statement from the Association for Acute CardioVascular Care (ACVC) of the European Society of Cardiology. European Heart Journal: Acute Cardiovascular Care, 11 (2), 173-185. doi: 10.1093/ehjacc/zuab122

Acute Heart Failure in the 2021 ESC Heart Failure Guidelines: A scientific statement from the Association for Acute CardioVascular Care (ACVC) of the European Society of Cardiology

2022

Journal Article

Biomarker development in cardiology: Reviewing the past to inform the future

Kott, Katharine A., Bishop, Michael, Yang, Christina H. J., Plasto, Toby M., Cheng, Daniel C., Kaplan, Adam I., Cullen, Louise, Celermajer, David S., Meikle, Peter J., Vernon, Stephen T. and Figtree, Gemma A. (2022). Biomarker development in cardiology: Reviewing the past to inform the future. Cells, 11 (3) 588, 588. doi: 10.3390/cells11030588

Biomarker development in cardiology: Reviewing the past to inform the future

2022

Journal Article

Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial

Chuang, Ming-yu Anthony, Gnanamanickam, Emmanuel S., Karnon, Jonathan, Lambrakis, Kristina, Horsfall, Matthew, Blyth, Andrew, Seshadri, Anil, Nguyen, Mau T., Briffa, Tom, Cullen, Louise A., Quinn, Stephen, French, John K. and Chew, Derek P. (2022). Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial. IJC Heart and Vasculature, 38 100933. doi: 10.1016/j.ijcha.2021.100933

Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial

2022

Journal Article

Implementation of more sensitive cardiac troponin T assay in a state-wide health service

Khan, Ehsan, Lambrakis, Kristina, Nazir, Sheraz A., Chuang, Anthony, Halabi, Amera, Tiver, Kathryn, Briffa, Tom, Cullen, Louise A., Horsfall, Matthew, French, John K., Sun, Benjamin C. and Chew, Derek P. (2022). Implementation of more sensitive cardiac troponin T assay in a state-wide health service. International Journal of Cardiology, 347, 66-72. doi: 10.1016/j.ijcard.2021.11.013

Implementation of more sensitive cardiac troponin T assay in a state-wide health service

2022

Journal Article

Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

Cullen, Louise, Collinson, Paul O. and Giannitsis, Evangelos (2022). Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities. Emergency Medicine Journal, 39 (11) emermed-2021-211907, 861-866. doi: 10.1136/emermed-2021-211907

Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

2022

Journal Article

Retrospective study of the prevalence and characteristics of adverse drug events in adults who present to an Australian emergency department

Brown, Nathan J., Doran, Elizabeth, Greenslade, Jaimi H., Lukin, Bill, Cottrell, Neil, Jaramillo, Fabian, Coombes, Ian, Donovan, Peter and Cullen, Louise (2022). Retrospective study of the prevalence and characteristics of adverse drug events in adults who present to an Australian emergency department. Emergency Medicine Australasia, 34 (4), 547-554. doi: 10.1111/1742-6723.13929

Retrospective study of the prevalence and characteristics of adverse drug events in adults who present to an Australian emergency department

2021

Journal Article

How to implement novel diagnostic algorithms for non-ST-segment elevation myocardial infarction in the emergency department

Cullen, Louise, Mills, Nicholas L, Morrow, David A and Mueller, Christian (2021). How to implement novel diagnostic algorithms for non-ST-segment elevation myocardial infarction in the emergency department. European Heart Journal. Acute Cardiovascular Care, 11 (1), 75-76. doi: 10.1093/ehjacc/zuab118

How to implement novel diagnostic algorithms for non-ST-segment elevation myocardial infarction in the emergency department

Current funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant

Past funding

  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study

    Principal Advisor

  • Doctor Philosophy

    Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study

    Principal Advisor

Completed supervision

Enquiries

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