Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

297 works between 2004 and 2026
All (297) Journal Article (258) Conference Publication (39)

41 - 60 of 297 works

2024

Journal Article

Biomarkers for diagnosis and prognostication of acute aortic syndromes

Morello, Fulvio, Nazerian, Peiman, Lupia, Enrico, Castelli, Matteo, Mills, Nicholas L, Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias, Jaffe, Allan S. and the Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2024). Biomarkers for diagnosis and prognostication of acute aortic syndromes. European Heart Journal: Acute Cardiovascular Care, 13 (2), 254-256. doi: 10.1093/ehjacc/zuae011

Biomarkers for diagnosis and prognostication of acute aortic syndromes

2023

Journal Article

Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design

Thulin, Ingrid Viola Lavesson, Jordalen, Silje Marie Farestveit, Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole Thomas, Collinson, Paul, Apple, Fred, Cullen, Louise, Norekval, Tone M., Wisloff, Torbjorn, Vikenes, Kjell, Omland, Torbjorn, Bjorneklett, Rune O. and Aakre, Kristin Moberg (2023). Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design. Scandinavian Cardiovascular Journal, 57 (1) 2272585, 1-7. doi: 10.1080/14017431.2023.2272585

Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design

2023

Journal Article

Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials

Lambrakis, Kristina, Khan, Ehsan, van den Merkhof, Anke, Papendick, Cynthia, Chuang, Anthony, Zhai, Yuze, Eng-Frost, Joanne, Rocheleau, Simon, Lehman, Sam J., Blyth, Andrew, Briffa, Tom, Quinn, Stephen, French, John K., Cullen, Louise and Chew, Derek P. (2023). Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials. International Journal of Cardiology, 393 131396, 1-8. doi: 10.1016/j.ijcard.2023.131396

Impacts of high sensitivity troponin T reporting on care and outcomes in clinical practice: interactions between low troponin concentrations and participant sex within two randomized clinical trials

2023

Journal Article

Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay

Meek, Robert, Cullen, Louise, Lu, Zhong, Nasis, Arthur, Kuhn, Lisa and Sorace, Laurence (2023). Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay. EMA - Emergency Medicine Australasia, 35 (6), 1005-1012. doi: 10.1111/1742-6723.14282

Suspected myocardial infarction in the emergency department: An evaluation of clinical thresholds for the Beckman Coulter Access hsTnI high-sensitivity cardiac troponin I assay

2023

Journal Article

Cardiac troponin T and I: back to basics

Mingels, Alma M., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian, Thielmann, Matthias and Study Group on Biomarkers of the ESC Association for Acute CardioVascular Care (2023). Cardiac troponin T and I: back to basics. European Heart Journal: Acute Cardiovascular Care, 12 (9), 631-632. doi: 10.1093/ehjacc/zuad084

Cardiac troponin T and I: back to basics

2023

Journal Article

Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol

Schults, Jessica A., Marsh, Nicole, Ullman, Amanda J., Kleidon, Tricia M., Ware, Robert S., Byrnes, Joshua, Young, Emily, Hall, Lisa, Keijzers, Gerben, Cullen, Louise, Calleja, Pauline, McTaggart, Steven, Peters, Nathan, Watkins, Stuart, Corley, Amanda, Brown, Christine, Lin, Zhen, Williamson, Frances, Burgess, Luke, Macfarlane, Fiona, Cooke, Marie, Battley, Callan and Rickard, Claire M. (2023). Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol. BMC Health Services Research, 23 (1) 587, 1-12. doi: 10.1186/s12913-023-09499-0

Improving difficult peripheral intravenous access requires thought, training and technology (DART3): a stepped-wedge, cluster randomised controlled trial protocol

2023

Journal Article

Healthcare cost burden of acute chest pain presentations

Dawson, Luke, Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew, Kaye, David, Cullen, Louise, Smith, Karen and Stub, Dion (2023). Healthcare cost burden of acute chest pain presentations. Emergency Medicine Journal, 40 (6) emermed-2022-212674, 1-7. doi: 10.1136/emermed-2022-212674

Healthcare cost burden of acute chest pain presentations

2023

Journal Article

Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome

Stephensen, Laura, Greenslade, Jaimi, Starmer, Katrina, Starmer, Greg, Stone, Richard, Bonnin, Robert, Brazzale, Anthony, Drahm‐Butler, Tileah, Campbell, Virginia, Davis, Tania, Mowatt, Elizabeth, Brown, Nathan, Proctor, Karlie, Ashover, Sarah, Milburn, Tanya, McCormack, Louise, Graves, Nicholas, Gatton, Michelle, Mahoney, Ray, Parsonage, William and Cullen, Louise (2023). Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome. Emergency Medicine Australasia, 35 (3), 442-449. doi: 10.1111/1742-6723.14138

Clinical characteristics of Aboriginal and Torres Strait Islander emergency department patients with suspected acute coronary syndrome

2023

Journal Article

High-sensitivity cardiac troponin in stable atherosclerotic vascular disease

Morrow, David A., Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Thielmann, Matthias (2023). High-sensitivity cardiac troponin in stable atherosclerotic vascular disease. European Heart Journal: Acute Cardiovascular Care, 12 (6), 396-398. doi: 10.1093/ehjacc/zuad054

High-sensitivity cardiac troponin in stable atherosclerotic vascular disease

2023

Journal Article

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

Doudesis, Dimitrios, Lee, Kuan Ken, Boeddinghaus, Jasper, Bularga, Anda, Ferry, Amy V., Tuck, Chris, Lowry, Matthew T. H., Lopez-Ayala, Pedro, Nestelberger, Thomas, Koechlin, Luca, Bernabeu, Miguel O., Neubeck, Lis, Anand, Atul, Schulz, Karen, Apple, Fred S., Parsonage, William, Greenslade, Jaimi H., Cullen, Louise, Pickering, John W., Than, Martin P., Gray, Alasdair, Mueller, Christian, Mills, Nicholas L., Richards, A. Mark, Pemberton, Chris, Troughton, Richard W., Aldous, Sally J., Brown, Anthony F. T., Dalton, Emily ... CoDE-ACS Investigators (2023). Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations. Nature Medicine, 29 (5), 1201-1210. doi: 10.1038/s41591-023-02325-4

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

2023

Journal Article

Personalized diagnosis in suspected myocardial infarction

Neumann, Johannes Tobias, Twerenbold, Raphael, Ojeda, Francisco, Aldous, Sally J., Allen, Brandon R., Apple, Fred S., Babel, Hugo, Christenson, Robert H., Cullen, Louise, Di Carluccio, Eleonora, Doudesis, Dimitrios, Ekelund, Ulf, Giannitsis, Evangelos, Greenslade, Jaimi, Inoue, Kenji, Jernberg, Tomas, Kavsak, Peter, Keller, Till, Lee, Kuan Ken, Lindahl, Bertil, Lorenz, Thiess, Mahler, Simon A., Mills, Nicholas L., Mokhtari, Arash, Parsonage, William, Pickering, John W., Pemberton, Christopher J., Reich, Christoph, Richards, A. Mark ... Zournazi, Anna (2023). Personalized diagnosis in suspected myocardial infarction. Clinical Research in Cardiology, 112 (9), 1288-1301. doi: 10.1007/s00392-023-02206-3

Personalized diagnosis in suspected myocardial infarction

2023

Journal Article

Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study

Fabre-Estremera, Blanca, Smith, Stephen W., Sandoval, Yader, Schulz, Karen, Okeson, Brynn, Cullen, Louise and Apple, Fred S. (2023). Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study. Clinical Chemistry, 69 (6), 627-636. doi: 10.1093/clinchem/hvad033

Rapid rule-out of myocardial infarction using a single high-sensitivity cardiac troponin I measurement strategy at presentation to the emergency department: The SAFETY Study

2023

Journal Article

Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey

Brownlee, Emily, Greenslade, Jaimi H, Kelly, Anne‐Maree, Meek, Robert A, Parsonage, William A and Cullen, Louise (2023). Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey. Emergency Medicine Australasia, 35 (2), 261-268. doi: 10.1111/1742-6723.14115

Snapshot of suspected acute coronary syndrome assessment processes in the emergency department: A national cross‐sectional survey

2023

Journal Article

Sex differences in epidemiology, care, and outcomes in patients with acute chest pain

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Davis, Esther, Bloom, Jason, Cox, Shelley, Nelson, Adam J., Okyere, Daniel, Anderson, David, Stephenson, Michael, Lefkovits, Jeffrey, Taylor, Andrew J., Nicholls, Stephen J., Cullen, Louise, Kaye, David, Smith, Karen and Stub, Dion (2023). Sex differences in epidemiology, care, and outcomes in patients with acute chest pain. Journal of the American College of Cardiology, 81 (10), 933-945. doi: 10.1016/j.jacc.2022.12.025

Sex differences in epidemiology, care, and outcomes in patients with acute chest pain

2023

Journal Article

Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research

Platz, Elke, Morrow, David A, Verbrugge, Frederik H, Vranckx, Pascal and Cullen, Louise (2023). Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research. European Heart Journal. Acute Cardiovascular Care, 12 (2), 77-79. doi: 10.1093/ehjacc/zuac170

Acute cardiovascular care in the Emergency Department and beyond: a call for interdisciplinary collaboration in clinical research

2023

Journal Article

Chest pain management using prehospital point-of-care troponin and paramedic risk assessment

Dawson, Luke P., Nehme, Emily, Nehme, Ziad, Zomer, Ella, Bloom, Jason, Cox, Shelley, Anderson, David, Stephenson, Michael, Ball, Jocasta, Zhou, Jennifer, Lefkovits, Jeffrey, Taylor, Andrew J., Horrigan, Mark, Chew, Derek P., Kaye, David, Cullen, Louise, Mihalopoulos, Cathrine, Smith, Karen and Stub, Dion (2023). Chest pain management using prehospital point-of-care troponin and paramedic risk assessment. JAMA Internal Medicine, 183 (3), 203-211. doi: 10.1001/jamainternmed.2022.6409

Chest pain management using prehospital point-of-care troponin and paramedic risk assessment

2022

Journal Article

Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

Apple, Fred S., Smith, Stephen W., Greenslade, Jaimi H., Sandoval, Yader, Parsonage, William, Ranasinghe, Isuru, Gaikwad, Niranjan J, Schulz, Karen, Stephensen, Laura, Schmidt, Christian W., Okeson, Brynn and Cullen, Louise (2022). Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk. Circulation, 146 (25), 1918-1929. doi: 10.1161/circulationaha.122.061148

Single high-sensitivity point of care whole blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

2022

Journal Article

Cardiac biomarkers in the field of cardio-oncology

Cardinale, Daniela, Mills, Nicholas L., Mueller, Christian, Jaffe, Allan, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Thielmann, Matthias (2022). Cardiac biomarkers in the field of cardio-oncology. European Heart Journal: Acute Cardiovascular Care, 11 (11), E1-E2. doi: 10.1093/ehjacc/zuac126

Cardiac biomarkers in the field of cardio-oncology

2022

Journal Article

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain

Eggers, Kai M., Hammarsten, Ola, Aldous, Sally J., Cullen, Louise, Greenslade, Jaimi H., Lindahl, Bertil, Parsonage, William A., Pemberton, Christopher J., Pickering, John W., Richards, A. Mark, Troughton, Richard W. and Than, Martin P. (2022). Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain. PLoS One, 17 (11) e0276645, 1-14. doi: 10.1371/journal.pone.0276645

Diagnostic and prognostic performance of the ratio between high-sensitivity cardiac troponin I and troponin T in patients with chest pain

2022

Journal Article

The retirement of CKMB

Jaffe, Allan S., Mills, Nicholas L., Mueller, Christian, Giannitsis, Evangelos, Daniels, Lori, Huber, Kurt, Mair, Johannes, Cullen, Louise, Hammarsten, Ola, Möckel, Martin, Krychtiuk, Konstantin, Thygesen, Kristian and Study Group on Biomarkers of the ESC Association for Acute CardioVascular Care (2022). The retirement of CKMB. European Heart Journal: Acute Cardiovascular Care, 11 (10), 784-785. doi: 10.1093/ehjacc/zuac113

The retirement of CKMB

Past funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant
  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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