
Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2018
Journal Article
Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department
Greenslade, Jaimi H., Chung, Kimberly, Parsonage, William A., Hawkins, Tracey, Than, Martin, Pickering, John W. and Cullen, Louise (2018). Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department. Emergency Medicine Australasia : EMA, 30 (1), 47-54. doi: 10.1111/1742-6723.12913
2018
Journal Article
Developing a value proposition for high-sensitivity troponin testing
St John, Andrew, Cullen, Louise, Jülicher, Paul and Price, Christopher P. (2018). Developing a value proposition for high-sensitivity troponin testing. Clinica Chimica Acta, 477, 154-159. doi: 10.1016/j.cca.2017.12.007
2018
Journal Article
ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway
Than, Martin P., Pickering, John W., Dryden, Jeremy M., Lord, Sally J., Aitken, S. Andrew, Aldous, Sally J., Allan, Kate E., Ardagh, Michael W., Bonning, John W. N., Callender, Rosie, Chapman, Laura R. E., Christiansen, Jonathan P., Cromhout, Andre P. J., Cullen, Louise, Deely, Joanne M., Devlin, Gerard P., Ferrier, Katherine A., Florkowski, Christopher M., Frampton, Christopher M. A., George, Peter M., Hamilton, Gregory J., Jaffe, Allan S., Kerr, Andrew J., Larkin, G. Luke, Makower, Richard M., Matthews, Timothy J. E., Parsonage, William A., Peacock, W. Frank, Peckler, Bradley F. ... Yates, Kim M. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway. Circulation, 137 (4), 354-363. doi: 10.1161/CIRCULATIONAHA.117.031984
2018
Journal Article
Indications and practical approach to non-invasive ventilation in acute heart failure
Masip, Josep, Frank Peacock, W., Price, Susanna, Cullen, Louise, Javier Martin-Sanchez, F., Seferovic, Petar, Maisel, Alan S., Miro, Oscar, Filippatos, Gerasimos, Vrints, Christiaan, Christ, Michael, Cowie, Martin, Platz, Elke, McMurray, John, DiSomma, Salvatore, Zeymer, Uwe, Bueno, Hector, Gale, Chris P., Lettino, Maddalena, Tavares, Mucio, Ruschitzka, Frank, Mebazaa, Alexandre, Harjola, Veli-Pekka and Mueller, Christian (2018). Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39 (1), 17-25. doi: 10.1093/eurheartj/ehx580
2018
Conference Publication
Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation
Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.
2018
Journal Article
An ovine model of hyperdynamic endotoxemia and vital organ metabolism
Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904
2018
Conference Publication
Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock
See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129
2017
Journal Article
Prohormones in the early diagnosis of cardiac syncope
Badertscher, Patrick, Nestelberger, Thomas, de Lavallaz, Jeanne du Fay, Than, Martin, Morawiec, Beata, Kawecki, Damian, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Bustamante, José, Geigy, Nicolas, Christ, Michael, Di Somma, Salvatore, Peacock, W. Frank, Cullen, Louise, Sarasin, François, Flores, Dayana, Tschuck, Michael, Boeddinghaus, Jasper, Twerenbold, Raphael, Wildi, Karin, Sabti, Zaid, Puelacher, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola, Shrestha, Samyut, Strebel, Ivo, Rentsch, Katharina, Keller, Dagmar I. ... Mueller, Christian (2017). Prohormones in the early diagnosis of cardiac syncope. Journal of the American Heart Association, 6 (12) e006592. doi: 10.1161/JAHA.117.006592
2017
Journal Article
Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome
Greenslade, Jaimi H., Carlton, Edward W., Van Hise, Christopher, Cho, Elizabeth, Hawkins, Tracey, Parsonage, William A., Tate, Jillian, Ungerer, Jacobus and Cullen, Louise (2017). Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome. Annals of Emergency Medicine, 71 (4), 439-451.e3. doi: 10.1016/j.annemergmed.2017.10.030
2017
Journal Article
Diving into research: a practical guide for emergency medicine trainees
Cullen, Louise and Brown, Nathan (2017). Diving into research: a practical guide for emergency medicine trainees. Emergency Medicine Australasia : EMA, 29 (6), 722-723. doi: 10.1111/1742-6723.12891
2017
Journal Article
Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome
Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter A., Blankenberg, Stefan, Neumann, Johannes, Söerensen, Nils A., Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J. E., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Ferry, Amy, Sandeman, Dennis, Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward ... Mills, Nicholas L. (2017). Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA - Journal of the American Medical Association, 318 (19), 1913-1924. doi: 10.1001/jama.2017.17488
2017
Journal Article
Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study
Hawkins, Tracey, Greenslade, Jaimi H., Suna, Jessica, Williams, Julian, Jensen, Matthew, Donohue, Maria, Ho, Elizabeth, Van Hise, Christopher, Egerton-Warburton, Diana and Cullen, Louise (2017). Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study. Academic Emergency Medicine , 25 (1), 26-32. doi: 10.1111/acem.13335
2017
Conference Publication
High-Sensitivity Cardiac Troponin I at Presentation in Patients With Suspected Acute Coronary Syndrome
Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter, Blankenberg, Stefan, Neumann, Johannes, Soerensen, Nils, Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward, Greaves, Kim, Korley, Frederick K. ... Mills, Nicholas L. (2017). High-Sensitivity Cardiac Troponin I at Presentation in Patients With Suspected Acute Coronary Syndrome. Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, Anaheim Ca, Nov 11-15, 2017. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2017
Journal Article
A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department
Pickering, John W., Flaws, Dylan, Smith, Stephen W., Greenslade, Jaimi, Cullen, Louise, Parsonage, William, Carlton, Edward, Mark Richards, A., Troughton, Richard, Pemberton, Christopher, George, Peter M. and Than, Martin P. (2017). A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department. Academic Emergency Medicine, 25 (4), 434-443. doi: 10.1111/acem.13343
2017
Journal Article
External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction
Van Hise, Christopher B., Greenslade, Jaimi H., Parsonage, William, Than, Martin, Young, Joanna and Cullen, Louise (2017). External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction. Clinical Biochemistry, 52, 161-163. doi: 10.1016/j.clinbiochem.2017.10.001
2017
Journal Article
Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy
Carlton, Edward Watts, Pickering, John William, Greenslade, Jaimi, Cullen, Louise, Than, Martin, Kendall, Jason, Body, Richard, Parsonage, William A., Khattab, Ahmed and Greaves, Kim (2017). Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy. Heart (British Cardiac Society), 104 (8), 665-672. doi: 10.1136/heartjnl-2017-311983
2017
Journal Article
Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection (vol 166, pg 715, 2017)
Pickering, J. W., Than, M. P., Cullen, L., Aldous, S., Ter Avest, E. and Body, R. (2017). Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection (vol 166, pg 715, 2017). Annals of Internal Medicine, 167 (7), 528-528.
2017
Journal Article
Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016)
Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E. G. (2017). Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016). Heart Lung and Circulation, 26 (10), 1117-1117. doi: 10.1016/j.hlc.2017.08.004
2017
Journal Article
Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study
Etaher, Aisha, Chew, Derek, Redfern, Julie, Briffa, Tom, Ellis, Chris, Hammett, Christopher, Lefkovits, Jeffrey, Elliott, John, Cullen, Louise, Brieger, David and French, John K. (2017). Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study. Heart, Lung and Circulation, 26 (10), 1051-1058. doi: 10.1016/j.hlc.2016.11.018
2017
Journal Article
Implementing change: evaluating the Accelerated Chest pain Risk Evaluation (ACRE) project
Parsonage, William A., Milburn, Tanya, Ashover, Sarah, Skoien, Wade, Greenslade, Jaimi H., McCormack, Louise and Cullen, Louise (2017). Implementing change: evaluating the Accelerated Chest pain Risk Evaluation (ACRE) project. Medical Journal of Australia, 207 (5), 201-205. doi: 10.5694/mja16.01479
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study
Principal Advisor
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Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
Completed supervision
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2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
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2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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