
Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2018
Journal Article
‘What the hell is water?’ How to use deliberate clinical inertia in common emergency department situations
Egerton‐Warburton, Diana, Cullen, Louise, Keijzers, Gerben and Fatovich, Daniel M. (2018). ‘What the hell is water?’ How to use deliberate clinical inertia in common emergency department situations. Emergency Medicine Australasia, 30 (3), 426-430. doi: 10.1111/1742-6723.12950
2018
Journal Article
Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: an observational study
Than, Martin P., Aldous, Sally J., Troughton, Richard W., Pemberton, Christopher J., Richards, A. Mark, Frampton, Christopher M. A., Florkowski, Christopher M., George, Peter M., Bailey, Samantha, Young, Joanna M., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William A., Everett, Brendan M., Peacock, W. Frank, Jaffe, Allan S. and Pickering, John W. (2018). Detectable high-sensitivity cardiac troponin within the population reference interval conveys high 5-year cardiovascular risk: an observational study. Clinical Chemistry, 64 (7), 1044-1053. doi: 10.1373/clinchem.2017.285700
2018
Journal Article
The assessment and management of chest pain in primary care: 'a focus on acute coronary syndrome'
Thomsett, Richard and Cullen, Louise (2018). The assessment and management of chest pain in primary care: 'a focus on acute coronary syndrome'. Australian Journal of General Practice, 47 (5), 246-251. doi: 10.31128/AFP-08-17-4304
2018
Journal Article
A critical evaluation of the Beckman Coulter Access hsTnI: analytical performance, reference interval and concordance
Pretorius, Carel J., Tate, Jillian R., Wilgen, Urs, Cullen, Louise and Ungerer, Jacobus P. J. (2018). A critical evaluation of the Beckman Coulter Access hsTnI: analytical performance, reference interval and concordance. Clinical Biochemistry, 55, 49-55. doi: 10.1016/j.clinbiochem.2018.03.003
2018
Journal Article
Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction
van der Linden, Noreen, Wildi, Karin, Twerenbold, Raphael, Pickering, John W, Than, Martin, Cullen, Louise, Greenslade, Jaimi, Parsonage, William, Nestelberger, Thomas, Boeddinghaus, Jasper, Badertscher, Patrick, Rubini Giménez, Maria, Klinkenberg, Lieke J J, Bekers, Otto, Schöni, Aline, Keller, Dagmar I, Sabti, Zaid, Puelacher, Christian, Cupa, Janosch, Schumacher, Lukas, Kozhuharov, Nikola, Grimm, Karin, Shrestha, Samyut, Flores, Dayana, Freese, Michael, Stelzig, Claudia, Strebel, Ivo, Miró, Òscar, Rentsch, Katharina ... Mueller, Christian (2018). Combining high sensitivity cardiac troponin I and cardiac troponin T in the early diagnosis of acute myocardial infarction. Circulation, 138 (10), CIRCULATIONAHA.117.032003-999. doi: 10.1161/CIRCULATIONAHA.117.032003
2018
Journal Article
Don't just do something, stand there! The value and art of deliberate clinical inertia
Keijzers, Gerben, Cullen, Louise, Egerton-Warburton, Diana and Fatovich, Daniel M (2018). Don't just do something, stand there! The value and art of deliberate clinical inertia. Emergency medicine Australasia : EMA, 30 (2), 273-278. doi: 10.1111/1742-6723.12922
2018
Journal Article
Characteristics and occurrence of type 2 myocardial infarction in emergency department patients: a prospective study
Greenslade, Jaimi H., Adikari, Thushani, Mueller, Christian, Sandoval, Yader, Nestelberger, Thomas, Parsonage, William, Hawkins, Tracey and Cullen, Louise (2018). Characteristics and occurrence of type 2 myocardial infarction in emergency department patients: a prospective study. Emergency Medicine Journal : EMJ, 35 (3), 169-175. doi: 10.1136/emermed-2017-206869
2018
Journal Article
Evaluating rapid rule-out of acute myocardial infarction by use of a high-sensitivity cardiac troponin I assay at presentation
Greenslade, Jaimi, Cho, Elizabeth, Van Hise, Christopher, Hawkins, Tracey, Parsonage, William, Ungerer, Jacobus, Tate, Jillian, Pretorius, Carel, Than, Martin and Cullen, Louise (2018). Evaluating rapid rule-out of acute myocardial infarction by use of a high-sensitivity cardiac troponin I assay at presentation. Clinical Chemistry, 64 (5), 820-829. doi: 10.1373/clinchem.2017.283887
2018
Journal Article
Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department
Greenslade, Jaimi H., Chung, Kimberly, Parsonage, William A., Hawkins, Tracey, Than, Martin, Pickering, John W. and Cullen, Louise (2018). Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department. Emergency Medicine Australasia : EMA, 30 (1), 47-54. doi: 10.1111/1742-6723.12913
2018
Journal Article
Developing a value proposition for high-sensitivity troponin testing
St John, Andrew, Cullen, Louise, Jülicher, Paul and Price, Christopher P. (2018). Developing a value proposition for high-sensitivity troponin testing. Clinica Chimica Acta, 477, 154-159. doi: 10.1016/j.cca.2017.12.007
2018
Journal Article
ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway
Than, Martin P., Pickering, John W., Dryden, Jeremy M., Lord, Sally J., Aitken, S. Andrew, Aldous, Sally J., Allan, Kate E., Ardagh, Michael W., Bonning, John W. N., Callender, Rosie, Chapman, Laura R. E., Christiansen, Jonathan P., Cromhout, Andre P. J., Cullen, Louise, Deely, Joanne M., Devlin, Gerard P., Ferrier, Katherine A., Florkowski, Christopher M., Frampton, Christopher M. A., George, Peter M., Hamilton, Gregory J., Jaffe, Allan S., Kerr, Andrew J., Larkin, G. Luke, Makower, Richard M., Matthews, Timothy J. E., Parsonage, William A., Peacock, W. Frank, Peckler, Bradley F. ... Yates, Kim M. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway. Circulation, 137 (4), 354-363. doi: 10.1161/CIRCULATIONAHA.117.031984
2018
Conference Publication
Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock
See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129
2018
Journal Article
Indications and practical approach to non-invasive ventilation in acute heart failure
Masip, Josep, Frank Peacock, W., Price, Susanna, Cullen, Louise, Javier Martin-Sanchez, F., Seferovic, Petar, Maisel, Alan S., Miro, Oscar, Filippatos, Gerasimos, Vrints, Christiaan, Christ, Michael, Cowie, Martin, Platz, Elke, McMurray, John, DiSomma, Salvatore, Zeymer, Uwe, Bueno, Hector, Gale, Chris P., Lettino, Maddalena, Tavares, Mucio, Ruschitzka, Frank, Mebazaa, Alexandre, Harjola, Veli-Pekka and Mueller, Christian (2018). Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39 (1), 17-25. doi: 10.1093/eurheartj/ehx580
2018
Conference Publication
Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation
Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.
2018
Journal Article
An ovine model of hyperdynamic endotoxemia and vital organ metabolism
Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904
2017
Journal Article
Prohormones in the early diagnosis of cardiac syncope
Badertscher, Patrick, Nestelberger, Thomas, de Lavallaz, Jeanne du Fay, Than, Martin, Morawiec, Beata, Kawecki, Damian, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Bustamante, José, Geigy, Nicolas, Christ, Michael, Di Somma, Salvatore, Peacock, W. Frank, Cullen, Louise, Sarasin, François, Flores, Dayana, Tschuck, Michael, Boeddinghaus, Jasper, Twerenbold, Raphael, Wildi, Karin, Sabti, Zaid, Puelacher, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola, Shrestha, Samyut, Strebel, Ivo, Rentsch, Katharina, Keller, Dagmar I. ... Mueller, Christian (2017). Prohormones in the early diagnosis of cardiac syncope. Journal of the American Heart Association, 6 (12) e006592. doi: 10.1161/JAHA.117.006592
2017
Journal Article
Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome
Greenslade, Jaimi H., Carlton, Edward W., Van Hise, Christopher, Cho, Elizabeth, Hawkins, Tracey, Parsonage, William A., Tate, Jillian, Ungerer, Jacobus and Cullen, Louise (2017). Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome. Annals of Emergency Medicine, 71 (4), 439-451.e3. doi: 10.1016/j.annemergmed.2017.10.030
2017
Journal Article
Diving into research: a practical guide for emergency medicine trainees
Cullen, Louise and Brown, Nathan (2017). Diving into research: a practical guide for emergency medicine trainees. Emergency Medicine Australasia : EMA, 29 (6), 722-723. doi: 10.1111/1742-6723.12891
2017
Journal Article
Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome
Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter A., Blankenberg, Stefan, Neumann, Johannes, Söerensen, Nils A., Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J. E., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Ferry, Amy, Sandeman, Dennis, Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward ... Mills, Nicholas L. (2017). Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA - Journal of the American Medical Association, 318 (19), 1913-1924. doi: 10.1001/jama.2017.17488
2017
Journal Article
Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study
Hawkins, Tracey, Greenslade, Jaimi H., Suna, Jessica, Williams, Julian, Jensen, Matthew, Donohue, Maria, Ho, Elizabeth, Van Hise, Christopher, Egerton-Warburton, Diana and Cullen, Louise (2017). Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study. Academic Emergency Medicine , 25 (1), 26-32. doi: 10.1111/acem.13335
Funding
Current funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study
Principal Advisor
Completed supervision
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2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
-
2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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