Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

268 works between 2004 and 2025
All (268) Journal Article (232) Conference Publication (36)

121 - 140 of 268 works

2018

Journal Article

Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department

Greenslade, Jaimi H., Chung, Kimberly, Parsonage, William A., Hawkins, Tracey, Than, Martin, Pickering, John W. and Cullen, Louise (2018). Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department. Emergency Medicine Australasia : EMA, 30 (1), 47-54. doi: 10.1111/1742-6723.12913

Modification of the Thrombolysis in Myocardial Infarction risk score for patients presenting with chest pain to the emergency department

2018

Journal Article

Developing a value proposition for high-sensitivity troponin testing

St John, Andrew, Cullen, Louise, Jülicher, Paul and Price, Christopher P. (2018). Developing a value proposition for high-sensitivity troponin testing. Clinica Chimica Acta, 477, 154-159. doi: 10.1016/j.cca.2017.12.007

Developing a value proposition for high-sensitivity troponin testing

2018

Journal Article

ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway

Than, Martin P., Pickering, John W., Dryden, Jeremy M., Lord, Sally J., Aitken, S. Andrew, Aldous, Sally J., Allan, Kate E., Ardagh, Michael W., Bonning, John W. N., Callender, Rosie, Chapman, Laura R. E., Christiansen, Jonathan P., Cromhout, Andre P. J., Cullen, Louise, Deely, Joanne M., Devlin, Gerard P., Ferrier, Katherine A., Florkowski, Christopher M., Frampton, Christopher M. A., George, Peter M., Hamilton, Gregory J., Jaffe, Allan S., Kerr, Andrew J., Larkin, G. Luke, Makower, Richard M., Matthews, Timothy J. E., Parsonage, William A., Peacock, W. Frank, Peckler, Bradley F. ... Yates, Kim M. (2018). ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway. Circulation, 137 (4), 354-363. doi: 10.1161/CIRCULATIONAHA.117.031984

ICare-ACS (improving care processes for patients with suspected acute coronary syndrome): a study of cross-system implementation of a National Clinical Pathway

2018

Conference Publication

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

2018

Journal Article

Indications and practical approach to non-invasive ventilation in acute heart failure

Masip, Josep, Frank Peacock, W., Price, Susanna, Cullen, Louise, Javier Martin-Sanchez, F., Seferovic, Petar, Maisel, Alan S., Miro, Oscar, Filippatos, Gerasimos, Vrints, Christiaan, Christ, Michael, Cowie, Martin, Platz, Elke, McMurray, John, DiSomma, Salvatore, Zeymer, Uwe, Bueno, Hector, Gale, Chris P., Lettino, Maddalena, Tavares, Mucio, Ruschitzka, Frank, Mebazaa, Alexandre, Harjola, Veli-Pekka and Mueller, Christian (2018). Indications and practical approach to non-invasive ventilation in acute heart failure. European Heart Journal, 39 (1), 17-25. doi: 10.1093/eurheartj/ehx580

Indications and practical approach to non-invasive ventilation in acute heart failure

2018

Conference Publication

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

2018

Journal Article

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

2017

Journal Article

Prohormones in the early diagnosis of cardiac syncope

Badertscher, Patrick, Nestelberger, Thomas, de Lavallaz, Jeanne du Fay, Than, Martin, Morawiec, Beata, Kawecki, Damian, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Bustamante, José, Geigy, Nicolas, Christ, Michael, Di Somma, Salvatore, Peacock, W. Frank, Cullen, Louise, Sarasin, François, Flores, Dayana, Tschuck, Michael, Boeddinghaus, Jasper, Twerenbold, Raphael, Wildi, Karin, Sabti, Zaid, Puelacher, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola, Shrestha, Samyut, Strebel, Ivo, Rentsch, Katharina, Keller, Dagmar I. ... Mueller, Christian (2017). Prohormones in the early diagnosis of cardiac syncope. Journal of the American Heart Association, 6 (12) e006592. doi: 10.1161/JAHA.117.006592

Prohormones in the early diagnosis of cardiac syncope

2017

Journal Article

Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome

Greenslade, Jaimi H., Carlton, Edward W., Van Hise, Christopher, Cho, Elizabeth, Hawkins, Tracey, Parsonage, William A., Tate, Jillian, Ungerer, Jacobus and Cullen, Louise (2017). Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome. Annals of Emergency Medicine, 71 (4), 439-451.e3. doi: 10.1016/j.annemergmed.2017.10.030

Diagnostic Accuracy of a New High-Sensitivity Troponin I Assay and Five Accelerated Diagnostic Pathways for Ruling Out Acute Myocardial Infarction and Acute Coronary Syndrome

2017

Journal Article

Diving into research: a practical guide for emergency medicine trainees

Cullen, Louise and Brown, Nathan (2017). Diving into research: a practical guide for emergency medicine trainees. Emergency Medicine Australasia : EMA, 29 (6), 722-723. doi: 10.1111/1742-6723.12891

Diving into research: a practical guide for emergency medicine trainees

2017

Journal Article

Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome

Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter A., Blankenberg, Stefan, Neumann, Johannes, Söerensen, Nils A., Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J. E., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Ferry, Amy, Sandeman, Dennis, Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward ... Mills, Nicholas L. (2017). Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA - Journal of the American Medical Association, 318 (19), 1913-1924. doi: 10.1001/jama.2017.17488

Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome

2017

Journal Article

Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study

Hawkins, Tracey, Greenslade, Jaimi H., Suna, Jessica, Williams, Julian, Jensen, Matthew, Donohue, Maria, Ho, Elizabeth, Van Hise, Christopher, Egerton-Warburton, Diana and Cullen, Louise (2017). Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study. Academic Emergency Medicine , 25 (1), 26-32. doi: 10.1111/acem.13335

Peripheral Intravenous Cannula Insertion and Use in the Emergency Department; an Intervention Study

2017

Conference Publication

High-Sensitivity Cardiac Troponin I at Presentation in Patients With Suspected Acute Coronary Syndrome

Chapman, Andrew R., Lee, Kuan Ken, McAllister, David A., Cullen, Louise, Greenslade, Jaimi H., Parsonage, William, Worster, Andrew, Kavsak, Peter, Blankenberg, Stefan, Neumann, Johannes, Soerensen, Nils, Westermann, Dirk, Buijs, Madelon M., Verdel, Gerard J., Pickering, John W., Than, Martin P., Twerenbold, Raphael, Badertscher, Patrick, Sabti, Zaid, Mueller, Christian, Anand, Atul, Adamson, Philip, Strachan, Fiona E., Gray, Alasdair, Body, Richard, Keevil, Brian, Carlton, Edward, Greaves, Kim, Korley, Frederick K. ... Mills, Nicholas L. (2017). High-Sensitivity Cardiac Troponin I at Presentation in Patients With Suspected Acute Coronary Syndrome. Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, Anaheim Ca, Nov 11-15, 2017. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

High-Sensitivity Cardiac Troponin I at Presentation in Patients With Suspected Acute Coronary Syndrome

2017

Journal Article

A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department

Pickering, John W., Flaws, Dylan, Smith, Stephen W., Greenslade, Jaimi, Cullen, Louise, Parsonage, William, Carlton, Edward, Mark Richards, A., Troughton, Richard, Pemberton, Christopher, George, Peter M. and Than, Martin P. (2017). A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department. Academic Emergency Medicine, 25 (4), 434-443. doi: 10.1111/acem.13343

A risk assessment score and initial high-sensitivity troponin combine to identify low risk of acute myocardial infarction in the emergency department

2017

Journal Article

External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction

Van Hise, Christopher B., Greenslade, Jaimi H., Parsonage, William, Than, Martin, Young, Joanna and Cullen, Louise (2017). External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction. Clinical Biochemistry, 52, 161-163. doi: 10.1016/j.clinbiochem.2017.10.001

External validation of heart-type fatty acid binding protein, high-sensitivity cardiac troponin, and electrocardiography as rule-out for acute myocardial infarction

2017

Journal Article

Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy

Carlton, Edward Watts, Pickering, John William, Greenslade, Jaimi, Cullen, Louise, Than, Martin, Kendall, Jason, Body, Richard, Parsonage, William A., Khattab, Ahmed and Greaves, Kim (2017). Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy. Heart (British Cardiac Society), 104 (8), 665-672. doi: 10.1136/heartjnl-2017-311983

Assessment of the 2016 National Institute for Health and Care Excellence high-sensitivity troponin rule-out strategy

2017

Journal Article

Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection (vol 166, pg 715, 2017)

Pickering, J. W., Than, M. P., Cullen, L., Aldous, S., Ter Avest, E. and Body, R. (2017). Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection (vol 166, pg 715, 2017). Annals of Internal Medicine, 167 (7), 528-528.

Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection (vol 166, pg 715, 2017)

2017

Journal Article

Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study

Etaher, Aisha, Chew, Derek, Redfern, Julie, Briffa, Tom, Ellis, Chris, Hammett, Christopher, Lefkovits, Jeffrey, Elliott, John, Cullen, Louise, Brieger, David and French, John K. (2017). Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study. Heart, Lung and Circulation, 26 (10), 1051-1058. doi: 10.1016/j.hlc.2016.11.018

Suspected ACS Patients Presenting With Myocardial Damage or a Type 2 Myocardial Infarction Have a Similar Late Mortality to Patients With a Type 1 Myocardial Infarction: A Report From the Australian and New Zealand 2012 SNAPSHOT ACS Study

2017

Journal Article

Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016)

Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E. G. (2017). Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016). Heart Lung and Circulation, 26 (10), 1117-1117. doi: 10.1016/j.hlc.2017.08.004

Corrigendum to 'National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the management of acute coronary syndromes 2016 (vol 25, pg 898, 2016)

2017

Journal Article

Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes

Cullen, Louise, Greenslade, Jaimi H., Hawkins, Tracey, Hammett, Chris, O'Kane, Shanen, Ryan, Kimberley, Parker, Kate, Schluter, Jessica, Dalton, Emily, Brown, Anthony F. T., Than, Martin, Peacock, W. Frank, Jaffe, Allan, O'Rourke, Peter K. and Parsonage, William A. (2017). Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes. Medical Journal of Australia, 207 (5), 195-200. doi: 10.5694/mja16.01351

Improved assessment of chest pain trial (IMPACT): assessing patients with possible acute coronary syndromes

Current funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant

Past funding

  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study

    Principal Advisor

  • Doctor Philosophy

    Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study

    Principal Advisor

Completed supervision

Enquiries

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