Professor Louise Cullen
Professor

Louise Cullen

Email: 

Background

Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.

As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.

More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.

Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.

Pre-Eminent Staff Specialist, Department of Emergency Medicine

Prof, Queensland University of Technology

A/Prof, University of Queensland

Royal Brisbane and Women’s Hospital

Brisbane, Queensland 4029, AUSTRALIA.

Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.

Email: louise.cullen@health.qld.gov.au

Twitter: @louiseacullen

Qualifications: MBBS (Hon) FACEM PhD

Availability

Professor Louise Cullen is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Clinical sciences Health Sciences

Research impacts

Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.

Search Professor Louise Cullen’s works on UQ eSpace

268 works between 2004 and 2025
All (268) Journal Article (232) Conference Publication (36)

161 - 180 of 268 works

2017

Journal Article

Differences in presentation, management and outcomes in women and men presenting to an emergency department with possible cardiac chest pain

Ruane, Lorcan, Greenslade, Jaime H., Parsonage, William, Hawkins, Tracey, Hammett, Christopher, Lam, Carolyn S. P., Knowlman, Thomas, Doig, Shaela and Cullen, Louise (2017). Differences in presentation, management and outcomes in women and men presenting to an emergency department with possible cardiac chest pain. Heart, Lung and Circulation, 26 (12), 1282-1290. doi: 10.1016/j.hlc.2017.01.003

Differences in presentation, management and outcomes in women and men presenting to an emergency department with possible cardiac chest pain

2017

Journal Article

Panic Disorder in Patients Presenting to the Emergency Department With Chest Pain: Prevalence and Presenting Symptoms

Greenslade, Jaimi H., Hawkins, Tracey, Parsonage, William and Cullen, Louise (2017). Panic Disorder in Patients Presenting to the Emergency Department With Chest Pain: Prevalence and Presenting Symptoms. Heart, lung & circulation, 26 (12), 1310-1316. doi: 10.1016/j.hlc.2017.01.001

Panic Disorder in Patients Presenting to the Emergency Department With Chest Pain: Prevalence and Presenting Symptoms

2017

Journal Article

Appropriate use of high-sensitivity cardiac troponin levels in patients with suspected acute myocardial infarction- reply

Carlton, Edward, Cullen, Louise and Body, Richard (2017). Appropriate use of high-sensitivity cardiac troponin levels in patients with suspected acute myocardial infarction- reply. JAMA Cardiology, 2 (2), 229-230. doi: 10.1001/jamacardio.2016.4256

Appropriate use of high-sensitivity cardiac troponin levels in patients with suspected acute myocardial infarction- reply

2017

Journal Article

Heart failure in patients presenting with dyspnoea to the emergency department in the Asia Pacific region: an observational study

Keijzers, Gerben, Kelly, Anne-Maree, Cullen, Louise, Klim, Sharon, Graham, Colin A., Craig, Simon, Kuan, Win Sen, Jones, Peter, Holdgate, Anna, Lawoko, Charles and Laribi, Said (2017). Heart failure in patients presenting with dyspnoea to the emergency department in the Asia Pacific region: an observational study. BMJ Open, 7 (2) e013812, e013812. doi: 10.1136/bmjopen-2016-013812

Heart failure in patients presenting with dyspnoea to the emergency department in the Asia Pacific region: an observational study

2017

Journal Article

European Society of Cardiology - Acute Cardiovascular Care Association position paper on acute heart failure: a call for interdisciplinary care

Mueller, Christian, Christ, Michael, Cowie, Martin, Cullen, Louise, Maisel, Alan S., Masip, Josep, Miro, Oscar, McMurray, John, Peacock, Frank W., Price, Susanna, DiSomma, Salvatore, Bueno, Hector, Zeymer, Uwe, Mebazaa, Alexandre and Acute Heart Failure Study Group of the ESC Acute Cardiovascular Care Association (2017). European Society of Cardiology - Acute Cardiovascular Care Association position paper on acute heart failure: a call for interdisciplinary care. European Heart Journal: Acute Cardiovascular Care, 6 (1), 81-86. doi: 10.1177/2048872615593279

European Society of Cardiology - Acute Cardiovascular Care Association position paper on acute heart failure: a call for interdisciplinary care

2017

Journal Article

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I

Neumann, Johannes Tobias, Sörensen, Nils Arne, Ojeda, Francisco, Schwemer, Tjark, Lehmacher, Jonas, Gönner, Saskia, Jarsetz, Nikolas, Keller, Till, Schaefer, Sarina, Renné, Thomas, Landmesser, Ulf, Clemmensen, Peter, Makarova, Nataliya, Schnabel, Renate B., Zeller, Tanja, Karakas, Mahir, Pickering, John W., Than, Martin, Parsonage, William, Greenslade, Jaimi, Cullen, Louise, Westermann, Dirk and Blankenberg, Stefan (2017). Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I. Clinical Chemistry, 63 (1), 394-402. doi: 10.1373/clinchem.2016.262659

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I

2017

Journal Article

Early Rule-Out and Rule-In Strategies for Myocardial Infarction

Cullen, Louise A., Mills, Nicholas L., Mahler, Simon and Body, Richard (2017). Early Rule-Out and Rule-In Strategies for Myocardial Infarction. Clinical Chemistry, 63 (1), 129-139. doi: 10.1373/clinchem.2016.254730

Early Rule-Out and Rule-In Strategies for Myocardial Infarction

2017

Journal Article

Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics

Apple, Fred S., Cullen, Louise, Felker, G. Michael, Ginsburg, Geoffrey and Morrow, David (2017). Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics. Clinical Chemistry, 63 (1), 1-4. doi: 10.1373/clinchem.2016.263350

Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics

2017

Journal Article

Point: The Use of Sex-Specific Cutpoints for High-Sensitivity Cardiac Troponin Assays

Cullen, Louise A. and Mills, Nicholas L. (2017). Point: The Use of Sex-Specific Cutpoints for High-Sensitivity Cardiac Troponin Assays. Clinical Chemistry, 63 (1), 261-263. doi: 10.1373/clinchem.2016.254672

Point: The Use of Sex-Specific Cutpoints for High-Sensitivity Cardiac Troponin Assays

2016

Journal Article

Does uric acid level provide additional risk stratification information in emergency patients with symptoms of possible acute coronary syndrome?

Jin, Harry, Greenslade, Jaimi H., Parsonage, William A., Hawkins, Tracey, Than, Martin and Cullen, Louise (2016). Does uric acid level provide additional risk stratification information in emergency patients with symptoms of possible acute coronary syndrome?. Critical Pathways in Cardiology, 15 (4), 169-173. doi: 10.1097/HPC.0000000000000092

Does uric acid level provide additional risk stratification information in emergency patients with symptoms of possible acute coronary syndrome?

2016

Journal Article

Assessment of the European society of cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction

Pickering, John W., Greenslade, Jaimi H., Cullen, Louise, Flaws, Dylan, Parsonage, William, Aldous, Sally, George, Peter, Worster, Andrew, Kavsak, Peter A. and Than, Martin P. (2016). Assessment of the European society of cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction. Circulation, 134 (20), 1532-1541. doi: 10.1161/CIRCULATIONAHA.116.022677

Assessment of the European society of cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction

2016

Conference Publication

Immediate Rule-out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-sensitivity Troponin I

Neumann, Johannes T., Sorensen, Nils A., Ojeda, Francisco, Schwemer, Tjark, Keller, Till, Renne, Thomas, Landmesser, Ulf, Clemmensen, Peter, Schnabel, Renate, Zeller, Tanja, Karakas, Mahir, Than, Martin, Parsonage, William, Greenslade, Jaimi, Cullen, Louise, Blankenberg, Stefan and Westermann, Dirk (2016). Immediate Rule-out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-sensitivity Troponin I. Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans La, Nov 12-16, 2016. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Immediate Rule-out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-sensitivity Troponin I

2016

Journal Article

Practical approach on frail older patients attended for acute heart failure

Martin-Sanchez, Francisco J., Christ, Michael, Miro, Òscar, Peacock, W. Frank, McMurray, John J., Bueno, Héctor, Maisel, Alan S., Cullen, Louise, Cowie, Martin R., Di Somma, Salvatore, Platz, Elke, Masip, Josep, Zeymer, Uwe, Vrints, Christiaan, Price, Susanna and Mueller, Christian (2016). Practical approach on frail older patients attended for acute heart failure. International Journal of Cardiology, 222, 62-71. doi: 10.1016/j.ijcard.2016.07.151

Practical approach on frail older patients attended for acute heart failure

2016

Journal Article

Use of the Theoretical Domains Framework to evaluate factors driving successful implementation of the Accelerated Chest pain Risk Evaluation (ACRE) project

Skoien, Wade, Page, Katie, Parsonage, William, Ashover, Sarah, Milburn, Tanya and Cullen, Louise (2016). Use of the Theoretical Domains Framework to evaluate factors driving successful implementation of the Accelerated Chest pain Risk Evaluation (ACRE) project. Implementation Science, 11 (1) 136. doi: 10.1186/s13012-016-0500-9

Use of the Theoretical Domains Framework to evaluate factors driving successful implementation of the Accelerated Chest pain Risk Evaluation (ACRE) project

2016

Journal Article

National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016

Chew, Derek P., Scott, Ian A., Cullen, Louise, French, John K., Briffa, Tom G., Tideman, Philip A., Woodruffe, Stephen, Kerr, Alistair, Branagan, Maree and Aylward, Philip E.G. (2016). National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016. Heart Lung and Circulation, 25 (9), 895-951. doi: 10.1016/j.hlc.2016.06.789

National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016

2016

Journal Article

Agreement between patient-reported and cardiology-adjudicated medical history in patients with possible ischemic chest pain: an observational study

Iliceto, Alessandro, Berndt, Sara Louise, Greenslade, Jaimi H., Parsonage, William A., Hammett, Christopher, Than, Martin, Hawkins, Tracey, Parker, Kate, O'Kane, Shannen and Cullen, Louise (2016). Agreement between patient-reported and cardiology-adjudicated medical history in patients with possible ischemic chest pain: an observational study. Critical Pathways in Cardiology, 15 (3), 121-125. doi: 10.1097/HPC.0000000000000082

Agreement between patient-reported and cardiology-adjudicated medical history in patients with possible ischemic chest pain: an observational study

2016

Journal Article

External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP)

Flaws, Dylan, Than, Martin, Scheuermeyer, Frank Xavier, Christenson, James, Boychuk, Barbara, Greenslade, Jaimi H., Aldous, Sally, Hammett, Christopher J., Parsonage, William A., Deely, Joanne M., Pickering, John W. and Cullen, Louise (2016). External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emergency Medicine Journal, 33 (9), 618-625. doi: 10.1136/emermed-2015-205028

External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP)

2016

Journal Article

Heart fatty acid binding protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction

Young, Joanna M., Pickering, John W., George, Peter M., Aldous, Sally J., Wallace, John, Frampton, Chris M., Troughton, Richard W., Richards, Mark A., Greenslade, Jaimi H., Cullen, Louise and Than, Martin P. (2016). Heart fatty acid binding protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction. BMC Emergency Medicine, 16 (1) 34, 34. doi: 10.1186/s12873-016-0089-y

Heart fatty acid binding protein and cardiac troponin: development of an optimal rule-out strategy for acute myocardial infarction

2016

Journal Article

Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests

Parsonage, W. A., Mueller, C., Greenslade, J. H., Wildi, K., Pickering, J., Than, M., Aldous, S., Boeddinghaus, J., Hammett, C. J., Hawkins, T., Nestelberger, T., Reichlin, T., Reidt, S., Rubin Gimenez, M., Tate, J. R., Twerenbold, R., Ungerer, J. P. and Cullen, L. (2016). Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests. Heart, 102 (16), 1279-86. doi: 10.1136/heartjnl-2016-309270

Validation of NICE diagnostic guidance for rule out of myocardial infarction using high-sensitivity troponin tests

2016

Journal Article

Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction

Pickering, John W., Greenslade, Jaimi H., Cullen, Louise, Flaws, Dylan, Parsonage, William, George, Peter, Worster, Andrew, Kavsak, Peter A. and Than, Martin P. (2016). Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction. Heart, 102 (16), 1270-1278. doi: 10.1136/heartjnl-2015-308505

Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction

Current funding

  • 2022 - 2025
    NUDG-ED: Trial of behavioural 'nudging' interventions to reduce unnecessary care for low back pain in the Emergency Department (NHMRC CTCS Externally administered by USyd)
    University of Sydney
    Open grant
  • 2021 - 2025
    Difficult peripheral intravenous catheter insertion: Australian considerations for sustainable implementation of ultrasound guided procedures
    NHMRC Partnership Projects
    Open grant

Past funding

  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2017 - 2020
    Improving Rapid Decision-Making in the Face of Uncertainty: A randomised trial of a 1-hour troponin protocol in suspected acute coronary syndromes (NHMRC Project Grant led by Flinders University)
    Flinders University
    Open grant
  • 2017 - 2020
    Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and manageme..(NHMRC Project Grant led by University of Western Australia)
    University of Western Australia
    Open grant
  • 2015 - 2020
    Centre of Research Excellence in Cardiovascular Outcomes Improvement (NHMRC CRE administered by Curtin University)
    Curtin University of Technology
    Open grant
  • 2011 - 2016
    Study 3: A decision analytic cost-effectiveness model for chest pain pathways
    QEMRF Project Grants Scheme
    Open grant
  • 2011 - 2016
    Rapid assessment of cardiac chest pain: the Australian and New Zealand Assessment of chest Pain Rule (ANZAP rule): A prospective validation study
    QEMRF Program Grants Scheme
    Open grant
  • 2010 - 2012
    Controlling Laboratory Test Ordering in Emergency Departments
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Factors influencing triage allocation for patients with acute myocardial infarction
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Accelerated pathway in the assessment of suspected acute coronary syndrome in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant

Availability

Professor Louise Cullen is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Automated data extraction of electronic health records using natural language processing for a statewide chest pain clinical data registry: The HER DECoDeR study

    Principal Advisor

  • Doctor Philosophy

    Data Extraction, Cohort Selection and Risk Stratification from Electronic Health Records of Emergency Department Suspected Acute Coronary Syndrome Patients: The Chest Pain DECoDeR Study

    Principal Advisor

Completed supervision

Enquiries

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