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Dr Fleur Garton
Dr

Fleur Garton

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Overview

Background

Fleur Garton is a researcher focused on improving outcomes for those with a neurological disease. She completed a Bachelor of Applied Science (Hons I) in 2008 at the University of Sydney. Pursing an interest in the molecular basis of skeletal muscle function she completed her honours and PhD at the Institute of Neuroscience and Muscle research at the Children’s Hospital Westmead. Fleur spent two-years as post-doctoral researcher at the Murdoch Childrens Research Institute, Melbourne. She was responsible for modelling the effect of gene dosage using rAAV vectors while helping to contribute to studies on human performance and health. In 2016, Fleur moved to work with Professor Naomi Wray at the Program in Complex Trait Genomics team at the University of Queensland. She was awarded a Bill Gole MND Postdoctoral fellowship from MNDRA in 2016, an NHMRC Early Career Researcher Fellowship (2017-2022) and is now the Scott Sullivan MND Research Fellow (2022). Her research program aims to further understand the genetic mechanisms of motor neurone disease (MND/ALS) using novel genomics analyses. This includes investigations into the use of cell-free DNA and other 'omic data to improve diagnosis and treatment. Fleur currently has research projects running at the Royal Brisbane Womens Hospital and the Mater Hospital together with local and international collaborators. Any potential participants or collaborators are encouraged to contact her on email about these projects.

Availability

Dr Fleur Garton is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, University of Sydney

Research interests

  • Motor Neurone Disease

  • Genetic variants influencing performance

  • Neuromuscular Disease

Works

Search Professor Fleur Garton’s works on UQ eSpace

44 works between 2009 and 2025

41 - 44 of 44 works

2011

Journal Article

Loss of IL-15 receptor alpha alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles

Pistilli, Emidio E., Bogdanovich, Sasha, Garton, Fleur, Yang, Nan, Gulbin, Jason P., Conner, Jennifer D., Anderson, Barbara G., Quinn, LeBris S., North, Kathryn, Ahima, Rexford S. and Khurana, Tejvir S. (2011). Loss of IL-15 receptor alpha alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles. Journal of Clinical Investigation, 121 (8), 3120-3132. doi: 10.1172/JCI44945

Loss of IL-15 receptor alpha alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles

2011

Journal Article

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling

Seto, Jane T., Lek, Monkol, Quinlan, Kate G.R., Houweling, Peter J., Zheng, Xi F., Garton, Fleur, MacArthur, Daniel G., Raftery, Joanna M., Garvey, Sean M., Hauser, Michael A., Yang, Nan, Head, Stewart I. and North, Kathryn N. (2011). Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling. Human Molecular Genetics, 20 (15) ddr196, 2914-2927. doi: 10.1093/hmg/ddr196

Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling

2010

Journal Article

Validation of an automated computational method for skeletal muscle fibre morphometry analysis

Garton, Fleur, Seto, Jane T., North, Kathryn N. and Yang, Nan (2010). Validation of an automated computational method for skeletal muscle fibre morphometry analysis. Neuromuscular Disorders, 20 (8), 540-547. doi: 10.1016/j.nmd.2010.06.012

Validation of an automated computational method for skeletal muscle fibre morphometry analysis

2009

Journal Article

α-actinin-3 and performance

Yang, Nan, Garton, Fleur and North, Kathryn (2009). α-actinin-3 and performance. Medicine and Sport Science, 54, 88-101. doi: 10.1159/000235698

α-actinin-3 and performance

Funding

Current funding

  • 2025 - 2027
    Proteomic Biomarkers for ALS Disease Prognosis and Progression Monitoring
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant
  • 2023 - 2026
    Organ Transplantation as a Model of Reversible Frailty
    NHMRC IDEAS Grants
    Open grant
  • 2022 - 2025
    Identifying MND risk genes to target novel therapeutic avenues
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2020 - 2025
    From the nucleus to the powerhouse: investigating how TDP-43-mitochondrial interactions wreak havoc in MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2020 - 2025
    A novel biomarker for ALS
    Cure for MND Foundation - Impact Grants
    Open grant

Past funding

  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2021 - 2022
    Dr Fleur Garton - AQ WRAP
    Advance Queensland Women's Research Assistance Program
    Open grant
  • 2021 - 2022
    UQ AWARE - Dr Fleur Garton
    UQ Amplify Women's Academic Research Equity
    Open grant
  • 2019 - 2020
    UQAWARE - Dr Fleur Garton
    UQ Amplify Women's Academic Research Equity
    Open grant
  • 2019 - 2020
    Profiling Cell-free DNA to detect Amyotrophic Lateral Sclerosis
    UQ Early Career Researcher
    Open grant
  • 2018 - 2020
    Cell-free DNA profiling in cases and disease-mimics to develop a biomarker test for Amyotrophic Lateral Sclerosis
    Brain Foundation
    Open grant
  • 2018 - 2019
    Cell-free DNA and ALS; insight into disease mechanisms and Progression (Susie Harris Travel Fellowship)
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2018
    Cell-free DNA and ALS; insight into disease mechanisms and progression
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2022
    The identification of novel genetic loci and pathways associated with ALS through interrogation of multiple integrated genomics data sets
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Nina Buscombe Award
    Motor Neurone Disease Association of Victoria
    Open grant
  • 2016
    MND Postdoctotral Fellowship - To identify novel genetic loci and pathways associated with ALS through interrogation of multiple integrated genomics data sets
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant

Supervision

Availability

Dr Fleur Garton is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis

    Principal Advisor

    Other advisors: Dr Allan McRae, Dr Jian Zeng

  • Doctor Philosophy

    Investigating the molecular basis of motor neurone disease using cell-free DNA

    Principal Advisor

    Other advisors: Dr Allan McRae, Professor Mark Midwinter

  • Doctor Philosophy

    Genetic architecture and evolution of complex traits across populations in humans

    Associate Advisor

    Other advisors: Professor Peter Visscher, Professor Naomi Wray, Dr Jian Zeng

  • Doctor Philosophy

    Cell-free DNA methodology for diagnosis and monitoring progression in Motor Neurone Disease

    Associate Advisor

    Other advisors: Dr Allan McRae

Media

Enquiries

Contact Dr Fleur Garton directly for media enquiries about:

  • gene tests for athletic ability
  • Genetics of Amyotrophic Lateral Sclerosis
  • Motor Neuron Disease
  • sport genetics

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