Dr

Naphak Modhiran

Email: 
Phone: 
+61 7 336 52485

Availability

Dr Naphak Modhiran is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Naphak Modhiran’s works on UQ eSpace

75 works between 2010 and 2025
All (75) Journal Article (66) Book Chapter (1) Conference Publication (1) Other Outputs (7)

61 - 75 of 75 works

2019

Journal Article

Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545

Modhiran, Naphak, Gandhi, Neha S., Wimmer, Norbert, Cheung, Stacey, Stacey, Katryn, Young, Paul R., Ferro, Vito and Watterson, Daniel (2019). Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545. Antiviral Research, 168, 121-127. doi: 10.1016/j.antiviral.2019.05.004

Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545

2019

Journal Article

Determinants of Zika virus host tropism uncovered by deep mutational scanning

Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4

Determinants of Zika virus host tropism uncovered by deep mutational scanning

2019

Journal Article

Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon

Tan, Yuen P., Houston, Sevan D., Modhiran, Naphak, Savchenko, Andrei I., Boyle, Glen M., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon. Chemistry – A European Journal, 25 (22) chem.201900591, 5664-5667. doi: 10.1002/chem.201900591

Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon

2019

Journal Article

CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain

Amarilla, Alberto A, Santos-Junior, Nilton Nascimento, Figueiredo, Mario Luis, Luiz, Joao Paulo Mesquita, Fumagalli, Marcilio Jorge, Colón, David F, Lippi, Veronica, Alfonso, Helda Liz, Lima-Junior, Djalma S, Trabuco, Amanda C, Spinieli, Richard L, Desidera, Amanda C, Leite-Panissi, Christie R A, Lauretti, Flávio, Mendoza, Silvia Elena Sánchez, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhaes, Galvao-Lima, Leonardo J, Bassi, Gabriel S, Penharvel Martíns, Sandra L B, Manrique, Wilson Gomez, Alves-Filho, José Carlos, Cunha, Fernando Q, Peng, Nias Y G, Modhiran, Naphak, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz T M and Aquino, Victor H (2019). CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain. The Journal of Infectious Diseases, 219 (12), 2015-2025. doi: 10.1093/infdis/jiz029

CCR2 plays a protective role in Rocio virus–induced encephalitis by promoting macrophage infiltration into the brain

2018

Book Chapter

Plugging the leak in Dengue shock

Watterson, Daniel, Modhiran, Naphak, Muller, David A., Stacey, Katryn J. and Young, Paul R. (2018). Plugging the leak in Dengue shock. Dengue and Zika: Control and Antiviral Treatment Strategies. (pp. 89-106) edited by Rolf Hilgenfeld and Subhash G. Vasudevan. Singapore, Singapore: Springer Nature. doi: 10.1007/978-981-10-8727-1_7

Plugging the leak in Dengue shock

2017

Journal Article

Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6

Modhiran, Naphak, Watterson, Daniel, Blumenthal, Antje, Baxter, Alan G., Young, Paul R. and Stacey, Katryn J. (2017). Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6. Immunology and Cell Biology, 95 (5), 491-495. doi: 10.1038/icb.2017.5

Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6

2017

Other Outputs

Dengue NS1 protein and its implication in dengue pathogenesis

Modhiran, Naphak (2017). Dengue NS1 protein and its implication in dengue pathogenesis. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2017.141

Dengue NS1 protein and its implication in dengue pathogenesis

2016

Journal Article

Riboflavin and ultraviolet light: impact on dengue virus infectivity

Faddy, H. M., Fryk, J. J., Watterson, D., Young, P. R., Modhiran, N., Muller, D. A., Keil, S. D., Goodrich, R. P. and Marks, D. C. (2016). Riboflavin and ultraviolet light: impact on dengue virus infectivity. Vox Sanguinis, 111 (3), 235-241. doi: 10.1111/vox.12414

Riboflavin and ultraviolet light: impact on dengue virus infectivity

2016

Journal Article

The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design

Watterson, Daniel, Modhiran, Naphak and Young, Paul R. (2016). The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design. Antiviral Research, 130, 7-18. doi: 10.1016/j.antiviral.2016.02.014

The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design

2015

Journal Article

Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

Stacey, Katryn J., Watterson, Daniel, Modhiran, Naphak and Young, Paul R. (2015). Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination". Science Translational Medicine, 7 (318) 318lr4, 318lr4-318lr4. doi: 10.1126/scitranslmed.aad8657

Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

2015

Journal Article

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Modhiran, Naphak, Watterson, Daniel, Muller, David A., Panetta, Adele K., Sester, David P., Liu, Lidong, Hume, David A., Stacey, Katryn J. and Young, Paul R. (2015). Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine, 7 (304) 304ra142, 1-10. doi: 10.1126/scitranslmed.aaa3863

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

2013

Journal Article

Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis

Phuklia, Weerawat, Kasisith, Jitra, Modhiran, Naphak, Rodpai, Ekkarat, Thannagith, Montri, Thongsakulprasert, Tipparat, Smith, Duncan R. and Ubol, Sukathida (2013). Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis. Virus Research, 177 (2), 179-188. doi: 10.1016/j.virusres.2013.08.011

Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis

2011

Journal Article

Intra-host diversities of the receptor-binding domain of stork faeces-derived avian H5N1 viruses and its significance as predicted by molecular dynamic simulation

Ubol, Sukathida, Suksatu, Ampa, Modhiran, Naphak, Sangma, Chak, Thitithanyanont, Arunee, Fukuda, Mark and Juthayothin, Tada (2011). Intra-host diversities of the receptor-binding domain of stork faeces-derived avian H5N1 viruses and its significance as predicted by molecular dynamic simulation. Journal of General Virology, 92 (2), 307-314. doi: 10.1099/vir.0.025973-0

Intra-host diversities of the receptor-binding domain of stork faeces-derived avian H5N1 viruses and its significance as predicted by molecular dynamic simulation

2010

Journal Article

Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse

Modhiran, Naphak, Kalayanarooj, Sirsipen and Ubol, Sukathida (2010). Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse. PLoS Neglected Tropical Diseases, 4 (12) e924, 1-12. doi: 10.1371/journal.pntd.0000924

Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse

2010

Journal Article

Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies

Ubol, Sukathida, Phuklia, Weerawat, Kalayanarooj, Siripen and Modhiran, Naphak (2010). Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies. Journal of Infectious Diseases, 201 (6), 923-935. doi: 10.1086/651018

Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies

Current funding

  • 2024 - 2027
    Broad-spectrum antibody therapy for Japanese Encephalitis serocomplex viruses
    Cumming Global Centre for Pandemic Therapeutics Foundation Grants
    Open grant
  • 2023 - 2025
    Broad-spectrum vaccine design for flaviviruses and henipaviruses
    NHMRC MRFF EMCR - Early to Mid-Career Researchers
    Open grant
  • 2023 - 2026
    Structurally informed vaccines and therapies to resist and counter JEV emergence
    NHMRC IDEAS Grants
    Open grant
  • 2022 - 2025
    Revealing bat antibody recognition mechanism against bat-borne viruses
    ARC Discovery Early Career Researcher Award
    Open grant

Past funding

  • 2022 - 2024
    How the synergy between flavivirus protein and noncoding RNA defeats antiviral response
    NHMRC IDEAS Grants
    Open grant
  • 2021 - 2022
    Molecular Clamp Stabilised HTLV-1 Envelope Glycoprotein for Vaccination and Immunotherapy
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)
    Open grant
  • 2020 - 2021
    Development of Hepatitis C (HCV) chimeric viruses for structural and vaccine application
    UQ Early Career Researcher
    Open grant
  • 2019 - 2022
    Intestinal barrier integrity in dengue virus infection
    NHMRC Project Grant
    Open grant
  • 2019 - 2022
    Structural insights into the function and antigenicity of the flavivirus NS1 protein
    NHMRC Project Grant
    Open grant

Availability

Dr Naphak Modhiran is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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