Overview
Availability
- Dr Naphak Modhiran is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Naphak Modhiran’s works on UQ eSpace
2021
Journal Article
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D. and Faulkner, Geoffrey J. (2021). No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. Cell Reports, 36 (7) 109530, 109530. doi: 10.1016/j.celrep.2021.109530
2021
Other Outputs
Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay
Shalash, Ahmed O., Azuar, Armira, Madge, Harrison Y. R., Modhiran, Naphak, Amarilla, Alberto A., Liang, Benjamin, Khromykh, Alexander, Watterson, Daniel, Young, Paul R., Toth, Istvan and Skwarczynski, Mariusz (2021). Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay. doi: 10.21203/rs.3.pex-1559/v1
2021
Journal Article
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions
Rawle, Daniel J., Le, Thuy T., Dumenil, Troy, Yan, Kexin, Tang, Bing, Nguyen, Wilson, Watterson, Daniel, Modhiran, Naphak, Hobson-Peters, Jody, Bishop, Cameron and Suhrbier, Andreas (2021). ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PLoS Pathogens, 17 (7) e1009723, 1-37. doi: 10.1371/journal.ppat.1009723
2021
Journal Article
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas ... Khromykh, Alexander A. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications, 12 (1) 3431, 3431. doi: 10.1038/s41467-021-23779-5
2021
Journal Article
A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses
Hardy, Joshua M., Newton, Natalee D., Modhiran, Naphak, Scott, Connor A. P., Venugopal, Hariprasad, Vet, Laura J., Young, Paul R., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nature Communications, 12 (1) 3266, 3266. doi: 10.1038/s41467-021-22773-1
2021
Other Outputs
Complete protection by a single dose skin patch delivered SARS-CoV-2 spike vaccine
McMillan, Christopher L.D., Choo, Jovin J.Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T.M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J.P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A.J. and Muller, David A. (2021). Complete protection by a single dose skin patch delivered SARS-CoV-2 spike vaccine. doi: 10.1101/2021.05.30.446357
2021
Other Outputs
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D. and Faulkner, Geoffrey J. (2021). No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. doi: 10.1101/2021.05.28.446065
2021
Journal Article
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Newton, Natalee D., Hardy, Joshua M., Modhiran, Naphak, Hugo, Leon E., Amarilla, Alberto A., Bibby, Summa, Venugopal, Hariprasad, Harrison, Jessica J., Traves, Renee J., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). The structure of an infectious immature flavivirus redefines viral architecture and maturation. Science Advances, 7 (20) eabe4507, 1-12. doi: 10.1126/sciadv.abe4507
2021
Journal Article
Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2
Albert, Simon, Amarilla, Alberto A., Trollope, Ben, Sng, Julian D.J., Setoh, Yin Xiang, Deering, Nathaniel, Modhiran, Naphak, Weng, Sung-Hsia, Melo, Maria C., Hutley, Nicholas, Nandy, Avik, Furlong, Michael J., Young, Paul R., Watterson, Daniel, Grinham, Alistair R. and Khromykh, Alexander A. (2021). Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2. Environmental Research, 196 110944, 110944. doi: 10.1016/j.envres.2021.110944
2021
Journal Article
Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2
Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269
2021
Journal Article
An optimized high-throughput immuno-plaque assay for SARS-CoV-2
Amarilla, Alberto A., Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Liang, Benjamin, McMillan, Christopher L. D., Freney, Morgan E, Cheung, Stacey T. M., Chappell, Keith J., Khromykh, Alexander A., Young, Paul R. and Watterson, Daniel (2021). An optimized high-throughput immuno-plaque assay for SARS-CoV-2. Frontiers in Microbiology, 12 625136, 625136. doi: 10.3389/fmicb.2021.625136
2021
Journal Article
Adjuvant selection for influenza and RSV prefusion subunit vaccines
Isaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel and Chappell, Keith J. (2021). Adjuvant selection for influenza and RSV prefusion subunit vaccines. Vaccines, 9 (2) 71, 1-14. doi: 10.3390/vaccines9020071
2021
Journal Article
A broadly protective antibody that targets the flavivirus NS1 protein
Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425
2020
Journal Article
Rapid response subunit vaccine design in the absence of structural information
Wijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2020). Rapid response subunit vaccine design in the absence of structural information. Frontiers in Immunology, 11 592370, 592370. doi: 10.3389/fimmu.2020.592370
2020
Journal Article
Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion
Thakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P. and Bailey, Dalan (2020). Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion. Journal of General Virology, 102 (1) 001506. doi: 10.1099/jgv.0.001506
2020
Other Outputs
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction
Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T, Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D.J., Chhabra, Mohit, Young, Paul R., Lima, Marcelo A., A.Yates, Edwin, Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M.A. ... Turnbull, Jeremy E. (2020). Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction. doi: 10.1101/2020.06.24.169334
2020
Other Outputs
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody
Nieto, Guillermo Valenzuela, Jara, Ronald, Watterson, Daniel, Modhiran, Naphak, Amarilla, Alberto A, Himelreichs, Johanna, Khromykh, Alexander A., Salinas, Constanza, Pinto, Teresa, Cheuquemilla, Yorka, Margolles, Yago, del Rey, Natalia López González, Miranda-Chacon, Zaray, Cuevas, Alexei, Berking, Anne, Deride, Camila, González-Moraga, Sebastián, Mancilla, Héctor, Maturana, Daniel, Langer, Andreas, Toledo, Juan Pablo, Müller, Ananda, Uberti, Benjamín, Krall, Paola, Ehrenfeld, Pamela, Blesa, Javier, Chana-Cuevas, Pedro, Rehren, German, Schwefel, David ... Rojas-Fernandez, Alejandro (2020). Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody. doi: 10.1101/2020.06.09.137935
2020
Other Outputs
Distinct systems serology features in children, elderly and COVID patients
Selva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Nguyen, Thi H.O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul, Wines, Bruce, Hogarth, P. Mark, Esterbauer, Robyn, Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Wheatley, Adam K. ... Chung, Amy W. (2020). Distinct systems serology features in children, elderly and COVID patients. doi: 10.1101/2020.05.11.20098459
2019
Journal Article
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus
Hobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888
2019
Journal Article
Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon
Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522
Funding
Current funding
Past funding
Supervision
Availability
- Dr Naphak Modhiran is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Structural and functional characterization of bat antiviral antibodies
Principal Advisor
Other advisors: Professor Daniel Watterson
-
Doctor Philosophy
Vaccines and therapies for emerging hemorrhagic viruses
Principal Advisor
Other advisors: Professor Daniel Watterson
-
Doctor Philosophy
Broad-spectrum vaccines and therapies for coronaviruses
Associate Advisor
Other advisors: Professor Daniel Watterson
-
Doctor Philosophy
Cooperation between sfRNA and non-structural protein NS5 for flavivirus immune evasion
Associate Advisor
Other advisors: Dr Andrii Slonchak, Professor Alexander Khromykh
-
Doctor Philosophy
Recombinant insect-specific alphaviruses as novel antigens for vaccine and diagnostic purposes
Associate Advisor
Other advisors: Associate Professor Jody Peters
-
Doctor Philosophy
Recombinant insect-specific alphaviruses as novel antigens for vaccine and diagnostic purposes
Associate Advisor
Other advisors: Associate Professor Jody Peters
-
Doctor Philosophy
Yellow Fever Virus Structure and Antigenicity
Associate Advisor
Other advisors: Associate Professor Jody Peters, Professor Daniel Watterson
-
Doctor Philosophy
Recombinant chimeric insect-specific viruses as novel antigens for diagnostic platforms
Associate Advisor
Other advisors: Associate Professor Jody Peters
-
Doctor Philosophy
Broad-spectrum vaccines and therapies for coronaviruses
Associate Advisor
Other advisors: Professor Daniel Watterson
-
Doctor Philosophy
Unravelling the cytokine-mediated immune cell selection in mRNA vaccine response
Associate Advisor
Other advisors: Professor Di Yu, Dr Yang Yang, Dr Zhian Chen
Completed supervision
-
2025
Doctor Philosophy
Recombinant insect-specific alphaviruses as novel antigens for vaccine and diagnostic purposes
Associate Advisor
Other advisors: Associate Professor Jody Peters
-
2024
Doctor Philosophy
The Structural and Antigenic Landscape of Emerging Encephalitic Flaviviruses
Associate Advisor
Other advisors: Associate Professor Jody Peters, Professor Daniel Watterson
-
2024
Doctor Philosophy
Yellow Fever Virus Structure and Antigenicity
Associate Advisor
Other advisors: Associate Professor Jody Peters, Professor Daniel Watterson
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