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2020 Journal Article Tissue-type plasminogen activator and tenecteplase-mediated increase in blood brain barrier permeability involves cell intrinsic complementKeragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe and Medcalf, Robert L. (2020). Tissue-type plasminogen activator and tenecteplase-mediated increase in blood brain barrier permeability involves cell intrinsic complement. Frontiers in Neurology, 11 577272, 1-12. doi: 10.3389/fneur.2020.577272 |
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2020 Journal Article Complement peptide receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology DatabaseCianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xiang X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2020). Complement peptide receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2020 (5). doi: 10.2218/gtopdb/f5/2020.5 |
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2020 Journal Article Is the C3a receptor antagonist SB290157 a useful pharmacological tool?Lee, John D., Taylor, Stephen M. and Woodruff, Trent M. (2020). Is the C3a receptor antagonist SB290157 a useful pharmacological tool?. British Journal of Pharmacology, 177 (24) bph.15264, 5677-5678. doi: 10.1111/bph.15264 |
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2020 Journal Article Acetate protects against intestinal ischemia-reperfusion injury independent of its cognate free fatty acid 2 receptorSchofield, Zoe, Wu, Mike C. L., Hansbro, Philip M., Cooper, Matthew A. and Woodruff, Trent M. (2020). Acetate protects against intestinal ischemia-reperfusion injury independent of its cognate free fatty acid 2 receptor. The FASEB Journal, 34 (8), 10418-10430. doi: 10.1096/fj.202000960R |
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2020 Journal Article A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease modelsKumar, Vinod, Lee, John D., Coulson, Elizabeth J. and Woodruff, Trent M. (2020). A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models. Journal of Neurochemistry, 158 (3) jnc.15119, 807-817. doi: 10.1111/jnc.15119 |
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2020 Journal Article COVID-19: Complement, coagulation, and collateral damageLo, Martin W., Kemper, Claudia and Woodruff, Trent M. (2020). COVID-19: Complement, coagulation, and collateral damage. The Journal of Immunology, 205 (6), ji2000644-1495. doi: 10.4049/jimmunol.2000644 |
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2020 Journal Article Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral SclerosisLee, John D., McDonald, Tanya S., Fung, Jenny N. T. and Woodruff, Trent M. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9 |
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2020 Journal Article Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitationHan, Felicity Y., Liu, Yun, Kumar, Vinod, Xu, Weizhi, Yang, Guangze, Zhao, Chun-Xia, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2020). Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation. International Journal of Pharmaceutics, 581 119291, 119291. doi: 10.1016/j.ijpharm.2020.119291 |
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2020 Journal Article Emerging insights into the structure and function of complement C5a receptorsPandey, Shubhi, Maharana, Jagannath, Li, Xaria X., Woodruff, Trent M. and Shukla, Arun K. (2020). Emerging insights into the structure and function of complement C5a receptors. Trends in Biochemical Sciences, 45 (8), 693-705. doi: 10.1016/j.tibs.2020.04.004 |
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2020 Conference Publication T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunityWest, Erin E., Freeley, Simon, Kolev, Martin, Niyonzima, Nathalie, Mogensen, Trine Hyrup, Woodruff, Trent M., Monk, Peter, Lappegard, Knut, Espevik, Terje, Mollnes, Tom Eirik, Christiansen, Mette and Kemper, Claudia (2020). T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.150.23 |
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2020 Journal Article The peripheral immune system and amyotrophic lateral sclerosisMcCombe, Pamela A., Lee, John D., Woodruff, Trent M. and Henderson, Robert D. (2020). The peripheral immune system and amyotrophic lateral sclerosis. Frontiers in Neurology, 11 279, 279. doi: 10.3389/fneur.2020.00279 |
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2020 Journal Article The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosisMcDonald, Tanya S., McCombe, Pamela A., Woodruff, Trent M. and Lee, John D. (2020). The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosis. The FASEB Journal, 34 (6) fj.201901781, 7225-7233. doi: 10.1096/fj.201901781 |
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2020 Journal Article Complement: bridging the innate and adaptive immune systems in sterile inflammationLo, Martin W. and Woodruff, Trent M. (2020). Complement: bridging the innate and adaptive immune systems in sterile inflammation. Journal of Leukocyte Biology, 108 (1) JLB.3MIR0220-270R, 339-351. doi: 10.1002/jlb.3mir0220-270r |
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2020 Journal Article Low-fouling fluoropolymers for bioconjugation and in vivo trackingFu, Changkui, Demir, Baris, Alcantara, Sheilajen, Kumar, Vinod, Han, Felicity, Kelly, Hannah, Tan, Xiao, Yu, Ye, Xu, Weizhi, Zhao, Jiacheng, Zhang, Cheng, Peng, Hui, Boyer, Cyrille, Woodruff, Trent, Kent, Stephen, Searles, Debra and Whittaker, Andrew (2020). Low-fouling fluoropolymers for bioconjugation and in vivo tracking. Angewandte Chemie International Edition, 59 (12), 4729-4735. doi: 10.1002/anie.201914119 |
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2020 Journal Article Editorial: The Role of Complement in TumorsRolfe, Barbara E., Pio, Ruben, Woodruff, Trent M., Markiewski, Maciej M. and Manthey, Helga D. (2020). Editorial: The Role of Complement in Tumors. Frontiers in Immunology, 11 139, 139. doi: 10.3389/fimmu.2020.00139 |
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2020 Journal Article Low‐fouling fluoropolymers for bioconjugation and in vivo trackingFu, Changkui, Demir, Baris, Alcantara, Sheilajen, Kumar, Vinod, Han, Felicity, Kelly, Hannah G., Tan, Xiao, Yu, Ye, Xu, Weizhi, Zhao, Jiacheng, Zhang, Cheng, Peng, Hui, Boyer, Cyrille, Woodruff, Trent M., Kent, Stephen J., Searles, Debra J. and Whittaker, Andrew K. (2020). Low‐fouling fluoropolymers for bioconjugation and in vivo tracking. Angewandte Chemie, 132 (12), 4759-4765. doi: 10.1002/ange.201914119 |
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2020 Journal Article The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteinsDeora, Vandana, Lee, John D., Albornoz, Eduardo A., McAlary, Luke, Jagaraj, Cyril J., Robertson, Avril A. B., Atkin, Julie D, Cooper, Matthew A., Schroder, Kate, Yerbury, Justin J., Gordon, Richard and Woodruff, Trent M. (2020). The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins. Glia, 68 (2) glia.23728, 407-421. doi: 10.1002/glia.23728 |
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2020 Journal Article Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in miceKumar, Vinod, Lee, John D., Clark, Richard J., Noakes, Peter G., Taylor, Stephen M. and Woodruff, Trent M. (2020). Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice. ACS Omega, 5 (5) acsomega.9b03735, 2345-2354. doi: 10.1021/acsomega.9b03735 |
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2020 Journal Article Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosisArbore, Giuseppina, Ong, Voon H., Costantini, Benedetta, Denton, Christopher P., Abraham, David, Placais, Leo, Blighe, Kevin, Mitchell, Lynne, Ellis, Richard, Heck, Susanne, Nocerino, Paola, Woodruff, Trent M., Kordasti, Shahram, Kemper, Claudia and Hourcade, Dennis E. (2020). Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosis. Cellular & Molecular Immunology, 17 (9), 1010-1013. doi: 10.1038/s41423-019-0360-8 |
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2020 Conference Publication Increased complement component 5a signalling drives severe asthma pathogenesisKim, R., Brown, A., Carroll, O., Hsu, A., Baines, K., Pathinayake, P., Kemper, C., Woodruff, T., Adcock,, Gibson, P., Wark, P., Horvat, J. and Hansbro, P. (2020). Increased complement component 5a signalling drives severe asthma pathogenesis. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health and Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777 |