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2010

Conference Publication

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

Wu, M. C. L., Moore, T. A., Manthey, H. D., Taylor, S. M. and Woodruff, T. M. (2010). The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.216

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

2009

Journal Article

Dendritic cell function in allostimulation is modulated by C5aR signaling

Peng, Qi, Li, Ke, Wang, Naiyin, Li, Qijun, Asgari, Elham, Lu, Bao, Woodruff, Trent M., Sacks, Steven H. and Zhou, Wuding (2009). Dendritic cell function in allostimulation is modulated by C5aR signaling. Journal of Immunology, 183 (10), 6058-6068. doi: 10.4049/jimmunol.0804186

Dendritic cell function in allostimulation is modulated by C5aR signaling

2009

Journal Article

Complement component 5a (C5a)

Manthey, Helga D., Woodruff, Trent M., Taylor, Stephen M. and Monk, Peter N. (2009). Complement component 5a (C5a). International Journal of Biochemistry and Cell Biology, 41 (11), 2114-2117. doi: 10.1016/j.biocel.2009.04.005

Complement component 5a (C5a)

2009

Journal Article

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

Lathia, Justin D., Chigurupati, Srinivasulu, Thundyil, John, Selvaraj, Pradeep K., Mughal, Mohamed R., Woodruff, Trent M., Chan, Sic L., Karamyan, Vardan T., Mattson, Mark P. and Arumugam, Thiruma V. (2009). Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke. Experimental Neurology, 221 (1), 107-114. doi: 10.1016/j.expneurol.2009.10.007

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

2009

Journal Article

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

Fonseca, Maria I., Ager, Rahasson R., Chu, Shu-Hui, Yazan, Ozkan, Sanderson, Sam D., LaFerla, Frank M., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2009). Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology, 183 (2), 1375-1383. doi: 10.4049/jimmunol.0901005

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

2009

Journal Article

Toll-like receptors in ischemia-reperfusion injury

Arumugam, Thiruma V., Okun, Eitan, Tang, Sung-Chun, Thundyil, John, Taylor, Stephen M. and Woodruff, Trent M. (2009). Toll-like receptors in ischemia-reperfusion injury. Shock, 32 (1), 4-16. doi: 10.1097/SHK.0b013e318193e333

Toll-like receptors in ischemia-reperfusion injury

2009

Journal Article

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

Proctor, Lavinia M., Moore, Tyson A., Monk, Peter N., Sanderson, Sam D., Taylor, Stephen M. and Woodruff, Trent M. (2009). Complement factors C3a and C5a have distinct hemodynamic effects in the rat. International Immunopharmacology, 9 (6), 800-806. doi: 10.1016/j.intimp.2009.03.002

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

2009

Journal Article

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

Arumugam, T V, Woodruff, T M, Lathia, J D, Selvaraj, P K, Mattson, M P and Taylor, S M (2009). Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience, 158 (3), 1074-1089. doi: 10.1016/j.neuroscience.2008.07.015

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

2009

Journal Article

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

Crane, James W., Baiquni, Gilang P., Sullivan, Robert K. P., Lee, John D, Sah, Pankaj, Taylor, Stephen M, Noakes, Peter G. and Woodruff, Trent (2009). The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres. Journal of Neuroinflammation, 6 (34) 34, 34.1-34.10. doi: 10.1186/1742-2094-6-34

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

2008

Journal Article

The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis

Woodruff, Trent M., Costantini, Kerina J., Crane, James W., Atkin, Julie D., Monk, Peter N., Taylor, Stephen M. and Noakes, Peter G. (2008). The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis. Journal of Immunology, 181 (12), 8727-8734. doi: 10.4049/jimmunol.181.12.8727

The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis

2008

Journal Article

Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors

Woodruff, Trent M., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors. Advances in Experimental Medicine and Biology, 632, 143-158.

Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors

2008

Journal Article

Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration

Morgan, Michael, Bulmer, Andrew C., Woodruff, Trent M., Proctor, Lavinia M., Williams, Hua M., Stocks, Shelli Z., Pollitt, Sandra, Taylor, Stephen M. and Shiels, Ian A (2008). Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration. European Journal of Pharmaceutical Sciences, 33 (4-5), 390-398. doi: 10.1016/j.ejps.2008.01.009

Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration

2008

Journal Article

Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

Ting, E., Guerrero, A. T. G., Cunha, T. M., Verri, W. A., Taylor, S. M., Woodruff, T. M., Cunha, F. Q. and Ferreira, S. H. (2008). Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain. British Journal of Pharmacology, 153 (5), 1043-1053. doi: 10.1038/sj.bjp.0707640

Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

2008

Journal Article

Targeting ischemic brain injury with intravenous immunoglobulin

Arumugam, Thiruma V., Selvaraj, Pradeep K., Woodruff, Trent M. and Mattson, Mark P. (2008). Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opinion on Therapeutic Targets, 12 (1), 19-29. doi: 10.1517/14728222.12.1.19

Targeting ischemic brain injury with intravenous immunoglobulin

2008

Conference Publication

Novel Haemodynamic effects of recombinant C5a and C5a des Arg in rats and mice

Moore, Tyson, Woodruff, Trent, Manthey, Helga, Monk, Peter, Taylor, Stephen and Shiels, Ian (2008). Novel Haemodynamic effects of recombinant C5a and C5a des Arg in rats and mice. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September-2 October 2008. Oxford, United Kingdom: Elseiver. doi: 10.1016/j.molimm.2008.08.165

Novel Haemodynamic effects of recombinant C5a and C5a des Arg in rats and mice

2008

Conference Publication

Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis

Manthey, Helga, Thomas, Anita, Taylor, Stephen, Woodruff, Trent, Moore, Tyson, Shiels, Ian and Rolfe, Barbara (2008). Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September - 2 October 2008. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.molimm.2008.08.167

Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis

2008

Conference Publication

Role of complement in motor neuron disease: Animal models and therapeutic potential of complement inhibitors

Woodruff, Trent R., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: Animal models and therapeutic potential of complement inhibitors. 4th Aegean Workshop on Complement Associated Diseases, Animal Models and Therapeutics, Porto Heli, Greece, 10-17 June 2007. New York, United States: Springer New York LLC. doi: 10.1007/978-0-387-78952-1_11

Role of complement in motor neuron disease: Animal models and therapeutic potential of complement inhibitors

2008

Conference Publication

Chronic complement-mediated inflammation promotes recovery after spinal cord injury

Beck, K. D., Nguyen, H. X., Woodruff, T. M. and Anderson, A. J. (2008). Chronic complement-mediated inflammation promotes recovery after spinal cord injury. American Society for Neurochemistry 39th Annual Meeting, San Antonio, United States, 1-5 March 2008. Chichester, West Sussex, United Kingom: Wiley-Blackwell. doi: 10.1111/j.1471-4159.2008.05160.x

Chronic complement-mediated inflammation promotes recovery after spinal cord injury

2008

Conference Publication

The role of C5a in reproductive impairment in the mouse and human

Denny, Kerina, Woodruff, Trent, Pavlovski, Dale, Manthey, Helga, Paul Colditz, Richard Finnell and Stephen Taylor (2008). The role of C5a in reproductive impairment in the mouse and human. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September - 2 October 2008. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.molimm.2008.08.164

The role of C5a in reproductive impairment in the mouse and human

2008

Conference Publication

Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis

Woodruff, Trent, Denny, Kerina, Crane, James, Atkin, Julie, Taylor, Steve and Noakes, Peter (2008). Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September-02 October 2008. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2008.08.202

Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis