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2011

Journal Article

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Woodruff, Trent M., Thundyil, John, Tang, Sung Chun, Sobey, Christopher G., Taylor, Stephen M. and Arumugam, Thiruma V. (2011). Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Molecular Neurodegeneration, 6 (1) 11, 1-19. doi: 10.1186/1750-1326-6-11

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

2011

Journal Article

Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis

Coulthard, Liam G., Costello, Jaclyn, Robinson, Brent, Shiels, Ian A., Taylor, Stephen M. and Woodruff, Ttrent M. (2011). Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis. Arthritis Research & Therapy, 13 (2) R42, R42-1-R42-10. doi: 10.1186/ar3278

Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis

2011

Journal Article

Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors

Hezmee, Mohd Noor Mohd, Kyaw-Tanner, Myat, Lee, Jia Yu Peppermint, Shiels, Ian A., Rolfe, Barbara, Woodruff, Trent and Mills, Paul C. (2011). Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors. Veterinary Immunology and Immunopathology, 139 (1), 50-56. doi: 10.1016/j.vetimm.2010.08.005

Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors

2010

Journal Article

Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death

Thundyil, John, Tang, Sung-Chun, Okun, Eitan, Shah, Kausik, Karamyan, Vardan T., Li , Yu-I, Woodruff, Trent M., Taylor, Stephen M., Jo, Dong-Gyu, Mattson, Mark P and Arumugam, Thiruma V. (2010). Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Experimental and Translational Stroke Medicine, 2 (1) 15, 15-1-15-8. doi: 10.1186/2040-7378-2-15

Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death

2010

Journal Article

The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells

Nishiura, Hiroshi, Tokita, Kazutaka, Li, Ying, Harada, Koichi, Woodruff, Trent W., Taylor, Stephen M., Nsiama, Tienabe K., Nishino, Norikazu and Yamamoto, Tetsuro (2010). The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells. Apoptosis, 15 (8), 966-981. doi: 10.1007/s10495-010-0511-y

The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells

2010

Journal Article

The role of the complement system and the activation fragment C5a in the central nervous system

Woodruff, T. M., Ager, R. R., Tenner, A. J., Noakes, P. G. and Taylor, S. M. (2010). The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medecine, 12 (2), 179-192. doi: 10.1007/s12017-009-8085-y

The role of the complement system and the activation fragment C5a in the central nervous system

2010

Journal Article

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

Ager, Rahasson R., Fonseca, Maira I., Chu, Shu-Hui, Sanderson, Sam D., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2010). Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease. Journal of Neurochemistry, 113 (2), 389-401. doi: 10.1111/j.1471-4159.2010.06595.x

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

2010

Journal Article

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

Beck, Kevin D., Nguyen, Hal X., Galvan, Manuel D., Salazar, Desireé L., Woodruff, Trent M. and Anderson, Aileen J. (2010). Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain, 133 (2), 433-447. doi: 10.1093/brain/awp322

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

2010

Conference Publication

Complement expression in mice throughout neural tube closure

Coulthard, L. G. J., Costantini, K. J., Lor, Mary, Simmons, D., Taylor, S. M. and Woodruff, T. M. (2010). Complement expression in mice throughout neural tube closure. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.163

Complement expression in mice throughout neural tube closure

2010

Conference Publication

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

Wu, M. C. L., Moore, T. A., Manthey, H. D., Taylor, S. M. and Woodruff, T. M. (2010). The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.216

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

2010

Conference Publication

C5aR protects against folate-deficiency induced neural tube defects in mice

Costantini, K. J., Coulthard, L. G. J., Lor, Mary, Woodruff, T. M., Callaway, L. K., Finnell, R. H. and Taylor, S. M. (2010). C5aR protects against folate-deficiency induced neural tube defects in mice. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.169

C5aR protects against folate-deficiency induced neural tube defects in mice

2010

Conference Publication

The role of complement-mediated inflammation in miscarriage and preterm birth

Costantini, K. J., Coulthard, L. G., Woodruff, T. M., Taylor, S. M. and Callaway, L. K. (2010). The role of complement-mediated inflammation in miscarriage and preterm birth. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.222

The role of complement-mediated inflammation in miscarriage and preterm birth

2010

Conference Publication

Dysregulation of the complement system in neurodegenerative disease

Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.215

Dysregulation of the complement system in neurodegenerative disease

2009

Journal Article

Dendritic cell function in allostimulation is modulated by C5aR signaling

Peng, Qi, Li, Ke, Wang, Naiyin, Li, Qijun, Asgari, Elham, Lu, Bao, Woodruff, Trent M., Sacks, Steven H. and Zhou, Wuding (2009). Dendritic cell function in allostimulation is modulated by C5aR signaling. Journal of Immunology, 183 (10), 6058-6068. doi: 10.4049/jimmunol.0804186

Dendritic cell function in allostimulation is modulated by C5aR signaling

2009

Journal Article

Complement component 5a (C5a)

Manthey, Helga D., Woodruff, Trent M., Taylor, Stephen M. and Monk, Peter N. (2009). Complement component 5a (C5a). International Journal of Biochemistry and Cell Biology, 41 (11), 2114-2117. doi: 10.1016/j.biocel.2009.04.005

Complement component 5a (C5a)

2009

Journal Article

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

Lathia, Justin D., Chigurupati, Srinivasulu, Thundyil, John, Selvaraj, Pradeep K., Mughal, Mohamed R., Woodruff, Trent M., Chan, Sic L., Karamyan, Vardan T., Mattson, Mark P. and Arumugam, Thiruma V. (2009). Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke. Experimental Neurology, 221 (1), 107-114. doi: 10.1016/j.expneurol.2009.10.007

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

2009

Journal Article

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

Fonseca, Maria I., Ager, Rahasson R., Chu, Shu-Hui, Yazan, Ozkan, Sanderson, Sam D., LaFerla, Frank M., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2009). Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology, 183 (2), 1375-1383. doi: 10.4049/jimmunol.0901005

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

2009

Journal Article

Toll-like receptors in ischemia-reperfusion injury

Arumugam, Thiruma V., Okun, Eitan, Tang, Sung-Chun, Thundyil, John, Taylor, Stephen M. and Woodruff, Trent M. (2009). Toll-like receptors in ischemia-reperfusion injury. Shock, 32 (1), 4-16. doi: 10.1097/SHK.0b013e318193e333

Toll-like receptors in ischemia-reperfusion injury

2009

Journal Article

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

Proctor, Lavinia M., Moore, Tyson A., Monk, Peter N., Sanderson, Sam D., Taylor, Stephen M. and Woodruff, Trent M. (2009). Complement factors C3a and C5a have distinct hemodynamic effects in the rat. International Immunopharmacology, 9 (6), 800-806. doi: 10.1016/j.intimp.2009.03.002

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

2009

Journal Article

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

Arumugam, T V, Woodruff, T M, Lathia, J D, Selvaraj, P K, Mattson, M P and Taylor, S M (2009). Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience, 158 (3), 1074-1089. doi: 10.1016/j.neuroscience.2008.07.015

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy