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2008 Conference Publication Protective effects of C5a receptor antagonism in a mouse model of atherosclerosisManthey, Helga, Thomas, Anita, Taylor, Stephen, Woodruff, Trent, Moore, Tyson, Shiels, Ian and Rolfe, Barbara (2008). Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September - 2 October 2008. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.molimm.2008.08.167 |
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2008 Conference Publication Chronic complement-mediated inflammation promotes recovery after spinal cord injuryBeck, K. D., Nguyen, H. X., Woodruff, T. M. and Anderson, A. J. (2008). Chronic complement-mediated inflammation promotes recovery after spinal cord injury. American Society for Neurochemistry 39th Annual Meeting, San Antonio, United States, 1-5 March 2008. Chichester, West Sussex, United Kingom: Wiley-Blackwell. doi: 10.1111/j.1471-4159.2008.05160.x |
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2008 Conference Publication The role of C5a in reproductive impairment in the mouse and humanDenny, Kerina, Woodruff, Trent, Pavlovski, Dale, Manthey, Helga, Paul Colditz, Richard Finnell and Stephen Taylor (2008). The role of C5a in reproductive impairment in the mouse and human. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September - 2 October 2008. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.molimm.2008.08.164 |
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2008 Conference Publication Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosisWoodruff, Trent, Denny, Kerina, Crane, James, Atkin, Julie, Taylor, Steve and Noakes, Peter (2008). Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September-02 October 2008. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2008.08.202 |
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2008 Journal Article Targeting ischemic brain injury with intravenous immunoglobulinArumugam, Thiruma V., Selvaraj, Pradeep K., Woodruff, Trent M. and Mattson, Mark P. (2008). Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opinion on Therapeutic Targets, 12 (1), 19-29. doi: 10.1517/14728222.12.1.19 |
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2008 Conference Publication Novel Haemodynamic effects of recombinant C5a and C5a des Arg in rats and miceMoore, Tyson, Woodruff, Trent, Manthey, Helga, Monk, Peter, Taylor, Stephen and Shiels, Ian (2008). Novel Haemodynamic effects of recombinant C5a and C5a des Arg in rats and mice. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, 28 September-2 October 2008. Oxford, United Kingdom: Elseiver. doi: 10.1016/j.molimm.2008.08.165 |
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2007 Journal Article The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand bindingScola, A. M., Higginbottom, A., Partridge, L, J., Reid, R. C., Woodruff, T., Taylor, S. M., Fairlie, D. P. and Monk, P. N. (2007). The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. Journal of Biological Chemistry, 282 (6), 3664-3671. doi: 10.1074/jbc.M609178200 |
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2006 Journal Article Transdermal pharmacology of small molecule cyclic C5a antagonistsProctor, Lavinia M, Woodruff, Trent M, Sharma, Prakirti, Shiels, Ian A and Taylor, Stephen M (2006). Transdermal pharmacology of small molecule cyclic C5a antagonists. Advances in experimental medicine and biology, 586, 329-345. |
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2006 Journal Article Complement mediators in ischemia-reperfusion injuryArumugam, Thiruma V., Magnus, Tim, Woodruff, Trent M., Proctor, Lavinia M., Shiels, Ian A., Taylor, Stephen M., A. H. Wu and J. Delanghe (2006). Complement mediators in ischemia-reperfusion injury. Clinica Chimica Acta, 374 (1-2), 33-45. doi: 10.1016/j.cca.2006.06.010 |
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2006 Journal Article Complement inhibitors selectively attenuate injury following administration of cobra venom factor to ratsProctor, Lavinia M., Strachan, Anna J., Woodruff, Trent M., Mahadevan, Indumathy B., Williams, H. Ming, Shiels, Ian A. and Taylor, Stephen M. (2006). Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats. International Immunopharmacology, 6 (8), 1224-1232. doi: 10.1016/j.intimp.2006.03.002 |
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2006 Journal Article Therapeutic activity of C5a receptor antagonists in a rat model of neurodegenerationWoodruff, Trent M., Crane, James W., Proctor, Lavinia. M., Buller, Kathryn M., Shek, Annie B., De Vos, Kurt, Pollitt, Sandra, Williams, Hua M., Shiels, Ian A., Monk, Peter N. and Taylor, Stephen M. (2006). Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. FASEB Journal, 20 (9), 1407-1417. doi: 10.1096/fj.05-5814com |
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2006 Journal Article Recent developments in C5/C5a inhibitorsProctor, Lavinia M., Woodruff, Trent M. and Taylor, Stephen M. (2006). Recent developments in C5/C5a inhibitors. Expert Opinion On Therapeutic Patents, 16 (4), 445-458. doi: 10.1517/13543776.16.4.445 |
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2006 Journal Article Complement factor 5a as a therapeutic targetWoodruff, T.M., Proctor, L.M., Strachan, A.J. and Taylor, S.M. (2006). Complement factor 5a as a therapeutic target. Drugs of The Future, 31 (4), 325-334. doi: 10.1358/dof.2006.031.04.980656 |
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2006 Book Chapter Transdermal Pharmacology of Small Molecule Cyclic C5a AntagonistsProctor, Lavinia M., Woodruff, Trent M., Sharma, Prakirti, Shiels, Ian A., Taylor, Stephen M. and Lambris, John D. (2006). Transdermal Pharmacology of Small Molecule Cyclic C5a Antagonists. Current Topics in Complement. (pp. 329-345) edited by John D. Lambris. New York: Springer. doi: 10.1007/0-387-34134-X_22 |
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2005 Journal Article Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding siteHigginbottom, Adrian, Cain, Stuart A., Woodruff, Trent M., Proctor, Lavinia M., Madala, Praveen K., Tyndall, Joel D. A., Taylor, Stephen M., Fairlie, David P. and Monk, Peter N. (2005). Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site. Journal of Biological Chemistry, 280 (18), 17831-17840. doi: 10.1074/jbc.M410797200 |
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2005 Journal Article A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitisWoodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005). A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 (5), 883-892. doi: 10.1016/j.intimp.2005.01.003 |
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2005 Journal Article Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel diseaseWoodruff, T. M., Pollitt, S., Proctor, L. M., Stocks, S. Z., Manthey, H. D., Williams, H. M., Mahadevan, I. B., Shiels, I. A. and Taylor, S. M. (2005). Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel disease. Journal of Pharmacology And Experimental Therapeutics, 314 (2), 811-817. doi: 10.1124/jpet.105.086835 |
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2004 Journal Article Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in ratsArumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and M. Colombo (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/j.jhep.2004.02.017 |
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2004 Journal Article Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in ratsArumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/S0168-8278(04)00066-2 |
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2004 Journal Article The role of the complement system in ischemia-reperfusion injuryArumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Granger, D. Neil and Taylor, Stephen M. (2004). The role of the complement system in ischemia-reperfusion injury. Shock, 21 (5), 401-409. doi: 10.1097/01.shk.0000121227.73012.86 |
