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2012

Conference Publication

Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models

Jain, Umang, Woodruff, Trent and Stadnyk, Andrew (2012). Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models. 2012 Advances in Inflammatory Bowel Diseases Crohn’s & Colitis Foundation’s National Clinical & Research Conference, Hollywood, Fl, United States, 13-15 December 2012. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1002/ibd.23058

Antagonizing C5aR reduces T Cell- IL-10-dependent colitis in pre-clinical models

2012

Conference Publication

Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia

Brennan, Faith H., Blomster, Linda V., Costantini, Alexander M., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia

2012

Conference Publication

The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization

Woodruff, Trent M., Wu, Mike C. L., Brennan, Faith H., Wetsel, Rick A., Ruitenberg, Marc J. and Taylor, Stephen M. (2012). The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.229

The C3a receptor mediates protection from intestinal ischemia reperfusion injuries by impairing neutrophil mobilization

2012

Book Chapter

Innate immunity in ALS

Lee, John D., Lee, Jia Y., Taylor, Stephen M., Noakes, Peter G. and Woodruff, Trent M. (2012). Innate immunity in ALS. Amyotrophic lateral sclerosis. (pp. 393-412) edited by Martin H. Maurer. Croatia: InTech - Open Access Publisher. doi: 10.5772/30341

Innate immunity in ALS

2011

Journal Article

Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats

Iyer, Abishek, Woodruff, Trent M., Wu, Mike C. L., Stylianou, Con, Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and Brown, Lindsay (2011). Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats. Journal of Cardiovascular Pharmacology, 58 (5), 479-486. doi: 10.1097/FJC.0b013e31822a7a09

Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats

2011

Journal Article

Inhibiting the C5-C5a receptor axis

Woodruff, Trent M., Nandakumar, Kutty S. and Tedesco, Francesco (2011). Inhibiting the C5-C5a receptor axis. Molecular Immunology, 48 (14), 1631-1642. doi: 10.1016/j.molimm.2011.04.014

Inhibiting the C5-C5a receptor axis

2011

Journal Article

Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice

Manthey, Helga D., Thomas, Anita C., Shiels, Ian A., Zernecke, Alma, Woodruff, Trent M., Rolfe, Barbara and Taylor, Stephen M. (2011). Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice. FASEB Journal, 25 (7), 2447-2455. doi: 10.1096/fj.10-174284

Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice

2011

Journal Article

Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats

Breivik, T., Gundersen, Y., Gjermo, P., Taylor, S. M., Woodruff, T. M. and Opstad, P. K. (2011). Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats. Journal of Periodontal Research, 46 (6), 643-647. doi: 10.1111/j.1600-0765.2011.01383.x

Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats

2011

Journal Article

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Woodruff, Trent M., Thundyil, John, Tang, Sung Chun, Sobey, Christopher G., Taylor, Stephen M. and Arumugam, Thiruma V. (2011). Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Molecular Neurodegeneration, 6 (1) 11, 1-19. doi: 10.1186/1750-1326-6-11

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

2011

Journal Article

Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis

Coulthard, Liam G., Costello, Jaclyn, Robinson, Brent, Shiels, Ian A., Taylor, Stephen M. and Woodruff, Ttrent M. (2011). Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis. Arthritis Research & Therapy, 13 (2) R42, R42-1-R42-10. doi: 10.1186/ar3278

Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis

2011

Journal Article

Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors

Hezmee, Mohd Noor Mohd, Kyaw-Tanner, Myat, Lee, Jia Yu Peppermint, Shiels, Ian A., Rolfe, Barbara, Woodruff, Trent and Mills, Paul C. (2011). Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors. Veterinary Immunology and Immunopathology, 139 (1), 50-56. doi: 10.1016/j.vetimm.2010.08.005

Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors

2010

Journal Article

Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death

Thundyil, John, Tang, Sung-Chun, Okun, Eitan, Shah, Kausik, Karamyan, Vardan T., Li , Yu-I, Woodruff, Trent M., Taylor, Stephen M., Jo, Dong-Gyu, Mattson, Mark P and Arumugam, Thiruma V. (2010). Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Experimental and Translational Stroke Medicine, 2 (1) 15, 15-1-15-8. doi: 10.1186/2040-7378-2-15

Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death

2010

Journal Article

The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells

Nishiura, Hiroshi, Tokita, Kazutaka, Li, Ying, Harada, Koichi, Woodruff, Trent W., Taylor, Stephen M., Nsiama, Tienabe K., Nishino, Norikazu and Yamamoto, Tetsuro (2010). The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells. Apoptosis, 15 (8), 966-981. doi: 10.1007/s10495-010-0511-y

The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells

2010

Journal Article

The role of the complement system and the activation fragment C5a in the central nervous system

Woodruff, T. M., Ager, R. R., Tenner, A. J., Noakes, P. G. and Taylor, S. M. (2010). The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medecine, 12 (2), 179-192. doi: 10.1007/s12017-009-8085-y

The role of the complement system and the activation fragment C5a in the central nervous system

2010

Journal Article

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

Ager, Rahasson R., Fonseca, Maira I., Chu, Shu-Hui, Sanderson, Sam D., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2010). Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease. Journal of Neurochemistry, 113 (2), 389-401. doi: 10.1111/j.1471-4159.2010.06595.x

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

2010

Journal Article

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

Beck, Kevin D., Nguyen, Hal X., Galvan, Manuel D., Salazar, Desireé L., Woodruff, Trent M. and Anderson, Aileen J. (2010). Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain, 133 (2), 433-447. doi: 10.1093/brain/awp322

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

2010

Conference Publication

Complement expression in mice throughout neural tube closure

Coulthard, L. G. J., Costantini, K. J., Lor, Mary, Simmons, D., Taylor, S. M. and Woodruff, T. M. (2010). Complement expression in mice throughout neural tube closure. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.163

Complement expression in mice throughout neural tube closure

2010

Conference Publication

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

Wu, M. C. L., Moore, T. A., Manthey, H. D., Taylor, S. M. and Woodruff, T. M. (2010). The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.216

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

2010

Conference Publication

C5aR protects against folate-deficiency induced neural tube defects in mice

Costantini, K. J., Coulthard, L. G. J., Lor, Mary, Woodruff, T. M., Callaway, L. K., Finnell, R. H. and Taylor, S. M. (2010). C5aR protects against folate-deficiency induced neural tube defects in mice. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.169

C5aR protects against folate-deficiency induced neural tube defects in mice

2010

Conference Publication

The role of complement-mediated inflammation in miscarriage and preterm birth

Costantini, K. J., Coulthard, L. G., Woodruff, T. M., Taylor, S. M. and Callaway, L. K. (2010). The role of complement-mediated inflammation in miscarriage and preterm birth. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.222

The role of complement-mediated inflammation in miscarriage and preterm birth