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2013

Journal Article

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

Lee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

2013

Journal Article

A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia

Smith, Maree T., Woodruff, Trent M., Wyse, Bruce D., Muralidharan, Arjun and Walther, Thomas (2013). A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Medicine, 14 (10), 1557-1568. doi: 10.1111/pme.12157

A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia

2013

Journal Article

Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia

Denny, Kerina J., Coulthard, Liam G., Finnell, Richard H., Callaway, Leonie K., Taylor, Stephen M. and Woodruff, Trent M. (2013). Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. Journal of Reproductive Immunology, 97 (2), 211-216. doi: 10.1016/j.jri.2012.11.006

Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia

2013

Journal Article

C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice

Denny, Kerina J., Coulthard, Liam G., Jeanes, Angela, Lisgo, Steven, Simmons, David G., Callaway, Leonie K., Wlodarczyk, Bogdan, Finnell, Richard H., Woodruff, Trent M. and Taylor, Stephen M. (2013). C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. Journal of Immunology, 190 (7), 3493-3499. doi: 10.4049/jimmunol.1203072

C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice

2013

Journal Article

C5L2: a controversial receptor of complement anaphylatoxin, C5a

Li, Rui, Coulthard, Liam G., Wu, M. C. L., Taylor, Stephen M. and Woodruff, Trent M. (2013). C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB Journal, 27 (3), 855-864. doi: 10.1096/fj.12-220509

C5L2: a controversial receptor of complement anaphylatoxin, C5a

2013

Journal Article

Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease

de Vries, Margreet R., Wezel, Anouk, Schepers, Abbey, van Santbrink, Peter J., Woodruff, Trent M., Niessen, Hans W. M., Hamming, Jaap F., Kuiper, Johan, Bot, Ilze and Quax, Paul H. A. (2013). Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease. Cardiovascular Research, 97 (2), 311-320. doi: 10.1093/cvr/cvs312

Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease

2013

Journal Article

The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10

Jain, U., Woodruff, T. M. and Stadnyk, A. W. (2013). The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10. British Journal of Pharmacology, 168 (2), 488-501. doi: 10.1111/j.1476-5381.2012.02183.x

The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10

2013

Journal Article

Neutrophils-A key component of ischemia-reperfusion injury

Schofield, Zoe Victoria, Woodruff, Trent Martin, Halai, Reena, Wu, Mike Chia-Lun and Cooper, Matthew Allister (2013). Neutrophils-A key component of ischemia-reperfusion injury. Shock, 40 (6), 463-470. doi: 10.1097/SHK.0000000000000044

Neutrophils-A key component of ischemia-reperfusion injury

2013

Conference Publication

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease

Mantovani, S., Li, R., Gordon, R., Kumar, V., Taylor, S. and Woodruff, T. M. (2013). Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease. World Congress on Huntington’s disease, Rio de Janeiro, Brazil, 15-18 September 2013. Amsterdam, Netherlands: I O S Press.

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease

2013

Journal Article

Complement in pregnancy: a delicate balance

Denny, Kerina J., Woodruff, Trent M., Taylor, Stephen M. and Callaway, Leonie K. (2013). Complement in pregnancy: a delicate balance. American Journal of Reproductive Immunology, 69 (1), 3-11. doi: 10.1111/aji.12000

Complement in pregnancy: a delicate balance

2013

Journal Article

Neural tube defects, folate, and immune modulation

Denny, Kerina J., Jeanes, Angela, Fathe, Kristin, Finnell, Richard H., Taylor, Stephen M. and Woodruff, Trent M. (2013). Neural tube defects, folate, and immune modulation. Birth Defects Research Part A - Clinical and Molecular Teratology, 97 (9), 602-609. doi: 10.1002/bdra.23177

Neural tube defects, folate, and immune modulation

2013

Conference Publication

Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)

Barrett, Helen L., Mcintyre, H. David, Denny, Kerina, Woodruff, Trent, Callaway, Leonie K. and Nitert, Marloes Dekker (2013). Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). American Diabetes Association 73rd Scientific Sessions, Chicago, IL United States, 21-25 June 2013 . Arlington, VA United States: American Diabetes Association. doi: 10.2337/db13-1-387

Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)

2012

Journal Article

Eph/Ephrin signaling in injury and inflammation

Coulthard, Mark G., Morgan, Michael, Woodruff, Trent M., Arumugam, Thiruma V., Taylor, Stephen M., Carpenter, Todd C., Martin Lackmann, and Boyd, Andrew W. (2012). Eph/Ephrin signaling in injury and inflammation. American Journal of Pathology, 181 (5), 1493-1503. doi: 10.1016/j.ajpath.2012.06.043

Eph/Ephrin signaling in injury and inflammation

2012

Journal Article

Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis

Pavlovski, Dale, Thundyil, John, Monk, Peter N., Wetsel, Rick A., Taylor, Stephen M. and Woodruff, Trent M. (2012). Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis. The FASEB Journal, 26 (9), 3680-3690. doi: 10.1096/fj.11-202382

Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis

2012

Journal Article

Complement activation in the injured central nervous system: Another dual-edged sword?

Brennan, Faith H., Anderson, Aileen J., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Complement activation in the injured central nervous system: Another dual-edged sword?. Journal of Neuroinflammation, 9 (1) 137, 137. doi: 10.1186/1742-2094-9-137

Complement activation in the injured central nervous system: Another dual-edged sword?

2012

Journal Article

Complement C5a regulates prolabor mediators in human placenta

Lappas, Martha, Woodruff, Trent M., Taylor, Stephen M. and Permezel, Michael (2012). Complement C5a regulates prolabor mediators in human placenta. Biology of Reproduction, 86 (6) 190, 190.1-190.9. doi: 10.1095/biolreprod.111.098475

Complement C5a regulates prolabor mediators in human placenta

2012

Journal Article

De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validation

Bellows-Peterson, Meghan L., Fung, Ho Ki, Floudas, Christodoulos A., Kieslich, Chris A., Zhang, Li, Morikis, Dimitrios, Wareham, Kathryn J., Monk, Peter N., Hawksworth, Owen A. and Woodruff, Trent M. (2012). De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validation. Journal of Medicinal Chemistry, 55 (9), 4159-4168. doi: 10.1021/jm201609k

De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validation

2012

Conference Publication

De novo protein design of agonists and antagonists of C5a receptors

Monkl, Peter N., Bellows-Peterson, Meghan L., Smadbeck, James, Floudas, Christodoulos A., Kieslich, Christopher A., Morikis, Dimitrios and Woodruff, Trent M. (2012). De novo protein design of agonists and antagonists of C5a receptors. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.097

De novo protein design of agonists and antagonists of C5a receptors

2012

Conference Publication

Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells

Hawksworth, Owen A., Coulthard, Liam G., Taylor, Stephen M., Wolvetang, Ernst J. and Woodruff, Trent M. (2012). Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells. 24th International Complement Workshop (ICW), Chania, Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.116

Expression of complement factors and functional C5a receptors in human embryonic stem cells, and induced pluripotent stem cells

2012

Conference Publication

The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia

Pavlovski, D., Thundyil, J., Taylor, S. M., Arumugam, T., V and Woodruff, T. M. (2012). The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia. Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney NSW Australia, 29-31 August 2012. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

The complement receptors CD88, C5L2 and C3AR mediate inflammatory injury following transient cerebral ischemia