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2010

Journal Article

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

Ager, Rahasson R., Fonseca, Maira I., Chu, Shu-Hui, Sanderson, Sam D., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2010). Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease. Journal of Neurochemistry, 113 (2), 389-401. doi: 10.1111/j.1471-4159.2010.06595.x

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease

2010

Journal Article

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

Beck, Kevin D., Nguyen, Hal X., Galvan, Manuel D., Salazar, Desireé L., Woodruff, Trent M. and Anderson, Aileen J. (2010). Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain, 133 (2), 433-447. doi: 10.1093/brain/awp322

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment

2010

Conference Publication

C5aR protects against folate-deficiency induced neural tube defects in mice

Costantini, K. J., Coulthard, L. G. J., Lor, Mary, Woodruff, T. M., Callaway, L. K., Finnell, R. H. and Taylor, S. M. (2010). C5aR protects against folate-deficiency induced neural tube defects in mice. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.169

C5aR protects against folate-deficiency induced neural tube defects in mice

2010

Conference Publication

The role of complement-mediated inflammation in miscarriage and preterm birth

Costantini, K. J., Coulthard, L. G., Woodruff, T. M., Taylor, S. M. and Callaway, L. K. (2010). The role of complement-mediated inflammation in miscarriage and preterm birth. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.222

The role of complement-mediated inflammation in miscarriage and preterm birth

2010

Conference Publication

Dysregulation of the complement system in neurodegenerative disease

Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.215

Dysregulation of the complement system in neurodegenerative disease

2010

Conference Publication

Complement expression in mice throughout neural tube closure

Coulthard, L. G. J., Costantini, K. J., Lor, Mary, Simmons, D., Taylor, S. M. and Woodruff, T. M. (2010). Complement expression in mice throughout neural tube closure. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.163

Complement expression in mice throughout neural tube closure

2010

Conference Publication

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

Wu, M. C. L., Moore, T. A., Manthey, H. D., Taylor, S. M. and Woodruff, T. M. (2010). The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury. XXIII International Complement Workshop, New York, NY, U.S.A., 1-5 August 2010. Oxford, U.K.: Pergamon Press. doi: 10.1016/j.molimm.2010.05.216

The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injury

2009

Journal Article

Dendritic cell function in allostimulation is modulated by C5aR signaling

Peng, Qi, Li, Ke, Wang, Naiyin, Li, Qijun, Asgari, Elham, Lu, Bao, Woodruff, Trent M., Sacks, Steven H. and Zhou, Wuding (2009). Dendritic cell function in allostimulation is modulated by C5aR signaling. Journal of Immunology, 183 (10), 6058-6068. doi: 10.4049/jimmunol.0804186

Dendritic cell function in allostimulation is modulated by C5aR signaling

2009

Journal Article

Complement component 5a (C5a)

Manthey, Helga D., Woodruff, Trent M., Taylor, Stephen M. and Monk, Peter N. (2009). Complement component 5a (C5a). International Journal of Biochemistry and Cell Biology, 41 (11), 2114-2117. doi: 10.1016/j.biocel.2009.04.005

Complement component 5a (C5a)

2009

Journal Article

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

Lathia, Justin D., Chigurupati, Srinivasulu, Thundyil, John, Selvaraj, Pradeep K., Mughal, Mohamed R., Woodruff, Trent M., Chan, Sic L., Karamyan, Vardan T., Mattson, Mark P. and Arumugam, Thiruma V. (2009). Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke. Experimental Neurology, 221 (1), 107-114. doi: 10.1016/j.expneurol.2009.10.007

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

2009

Journal Article

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

Fonseca, Maria I., Ager, Rahasson R., Chu, Shu-Hui, Yazan, Ozkan, Sanderson, Sam D., LaFerla, Frank M., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2009). Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology, 183 (2), 1375-1383. doi: 10.4049/jimmunol.0901005

Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

2009

Journal Article

Toll-like receptors in ischemia-reperfusion injury

Arumugam, Thiruma V., Okun, Eitan, Tang, Sung-Chun, Thundyil, John, Taylor, Stephen M. and Woodruff, Trent M. (2009). Toll-like receptors in ischemia-reperfusion injury. Shock, 32 (1), 4-16. doi: 10.1097/SHK.0b013e318193e333

Toll-like receptors in ischemia-reperfusion injury

2009

Journal Article

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

Proctor, Lavinia M., Moore, Tyson A., Monk, Peter N., Sanderson, Sam D., Taylor, Stephen M. and Woodruff, Trent M. (2009). Complement factors C3a and C5a have distinct hemodynamic effects in the rat. International Immunopharmacology, 9 (6), 800-806. doi: 10.1016/j.intimp.2009.03.002

Complement factors C3a and C5a have distinct hemodynamic effects in the rat

2009

Journal Article

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

Arumugam, T V, Woodruff, T M, Lathia, J D, Selvaraj, P K, Mattson, M P and Taylor, S M (2009). Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience, 158 (3), 1074-1089. doi: 10.1016/j.neuroscience.2008.07.015

Neuroprotection in stroke by complement inhibition and immunoglobulin therapy

2009

Journal Article

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

Crane, James W., Baiquni, Gilang P., Sullivan, Robert K. P., Lee, John D, Sah, Pankaj, Taylor, Stephen M, Noakes, Peter G. and Woodruff, Trent (2009). The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres. Journal of Neuroinflammation, 6 (34) 34, 34.1-34.10. doi: 10.1186/1742-2094-6-34

The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres

2008

Journal Article

The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis

Woodruff, Trent M., Costantini, Kerina J., Crane, James W., Atkin, Julie D., Monk, Peter N., Taylor, Stephen M. and Noakes, Peter G. (2008). The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis. Journal of Immunology, 181 (12), 8727-8734. doi: 10.4049/jimmunol.181.12.8727

The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis

2008

Journal Article

Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors

Woodruff, Trent M., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors. Advances in Experimental Medicine and Biology, 632, 143-158.

Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors

2008

Journal Article

Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration

Morgan, Michael, Bulmer, Andrew C., Woodruff, Trent M., Proctor, Lavinia M., Williams, Hua M., Stocks, Shelli Z., Pollitt, Sandra, Taylor, Stephen M. and Shiels, Ian A (2008). Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration. European Journal of Pharmaceutical Sciences, 33 (4-5), 390-398. doi: 10.1016/j.ejps.2008.01.009

Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration

2008

Journal Article

Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

Ting, E., Guerrero, A. T. G., Cunha, T. M., Verri, W. A., Taylor, S. M., Woodruff, T. M., Cunha, F. Q. and Ferreira, S. H. (2008). Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain. British Journal of Pharmacology, 153 (5), 1043-1053. doi: 10.1038/sj.bjp.0707640

Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain

2008

Journal Article

Targeting ischemic brain injury with intravenous immunoglobulin

Arumugam, Thiruma V., Selvaraj, Pradeep K., Woodruff, Trent M. and Mattson, Mark P. (2008). Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opinion on Therapeutic Targets, 12 (1), 19-29. doi: 10.1517/14728222.12.1.19

Targeting ischemic brain injury with intravenous immunoglobulin