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2014 Journal Article Derivation of ligands for the complement C3a receptor from the C-terminus of C5aHalai, Reena, Bellows-Peterson, Meghan L., Branchett, Will, Smadbeck, James, Kieslich, Chris A., Croker, Daniel E., Cooper, Matthew A., Morikis, Dimitrios, Woodruff, Trent M., Floudas, Christodoulos A. and Monk, Peter N. (2014). Derivation of ligands for the complement C3a receptor from the C-terminus of C5a. European Journal of Pharmacology, 745, 176-181. doi: 10.1016/j.ejphar.2014.10.041 |
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2014 Journal Article Brief report: Complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2Hawksworth, Owen A., Coulthard, Liam G., Taylor, Stephen M., Wolvetang, Ernst J. and Woodruff, Trent M. (2014). Brief report: Complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2. Stem Cells, 32 (12), 3278-3284. doi: 10.1002/stem.1801 |
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2014 Journal Article Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methodsKhan, Nemat, Woodruff, Trent M. and Smith, Maree T. (2014). Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. Pharmacology Biochemistry and Behavior, 126, 13-27. doi: 10.1016/j.pbb.2014.09.003 |
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2014 Journal Article Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosisGu H., Mickler E.A., Cummings O.W., Sandusky G.E., Weber D.J., Gracon A., Woodruff T., Wilkes D.S. and Vittal R. (2014). Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis. FASEB Journal, 28 (10), 4223-4234. doi: 10.1096/fj.13-247650 |
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2014 Journal Article Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient bloodMantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005 |
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2014 Journal Article Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and dockingTamamis, Phanourios, Kieslich, Chris A., Nikiforovich, Gregory V., Woodruff, Trent M., Morikis, Dimitrios and Archontis, Georgios (2014). Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking. BMC Biophysics, 7 (1) 5, 1-16. doi: 10.1186/2046-1682-7-5 |
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2014 Journal Article Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)Barrett, Helen L., Kubala, Marta H., Scholz Romero, Katherin, Denny, Kerina J., Woodruff, Trent M., McIntyre, H. David, Callaway, Leonie K. and Nitert, Marloes Dekker (2014). Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). PLoS One, 9 (8) e104826, e104826.1-e104826.8. doi: 10.1371/journal.pone.0104826 |
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2014 Conference Publication Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord InjuryRuitenberg, Marc J., Brennan, Faith H., Gordon, Richard, Blomster, Linda V., Lao, Hong Wa, Cowin, Gary J., Taylor, Stephen M. and Woodruff, Trent M. (2014). Acute Antagonism of the Complement Anaphylatoxin Receptor C5Ar Improves the Outcome From Experimental Spinal Cord Injury. 11th Symposium of the International-Neurotrauma-Society, Budapest, Hungary, 19-23 March 2014. New Rochelle, NY United States: Mary Ann Liebert. |
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2014 Conference Publication C3a and C5a homeostasis in health and diseaseWoodruff, Trent M. (2014). C3a and C5a homeostasis in health and disease. 25th International Complement Workshop, Rio de Janeiro Brazil, 14-18 September 2014. Kidlington, Oxford, United Kingdom: Pergamon Press. |
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2014 Journal Article Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injuryDe Hoog, Vince C., Timmers, Leo, Van Duijvenvoorde, Amerik, De Jager, Saskia C. A., Van Middelaar, Ben J., Smeets, Mirjam B., Woodruff, Trent M., Doevendans, Pieter A., Pasterkamp, Gerard, Hack, C. Erik and De Kleijn, Dominique P. V. (2014). Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury. Cardiovascular Research, 103 (4), 521-529. doi: 10.1093/cvr/cvu153 |
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2014 Journal Article Increased placental expression of fibroblast growth factor 21 in gestational diabetes mellitusDekker Nitert, Marloes, Barrett, Helen L., Kubala, Marta H., Scholz Romero, Katherin, Denny, Kerina J., Woodruff, Trent M., David McIntyre, H. David and Callaway, Leonie K. (2014). Increased placental expression of fibroblast growth factor 21 in gestational diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 99 (4), E591.1-E591.8. doi: 10.1210/jc.2013-2581 |
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2014 Conference Publication Discovery of novel selective C5a2 ligands that can modulate IL-6 releAse from macrophagesCroker, Daniel E., Halai, Reena, Kaeslin, Geraldine, Morikis, Dimitrios, Woodruff, Trent, Floudas, Christodoulos A., Monk, Peter N. and Cooper, Matthew A. (2014). Discovery of novel selective C5a2 ligands that can modulate IL-6 releAse from macrophages. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, Oct 26-29, 2014. London United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.039 |
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2013 Journal Article Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosisLee, John D., Kamaruzaman, Nur A., Fung, Jenny N. T., Taylor, Stephen M., Turner, Bradley J., Atkin, Julie D., Woodruff, Trent M. and Noakes, Peter G. (2013). Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 10 (1) 119, 119. doi: 10.1186/1742-2094-10-119 |
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2013 Journal Article A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root gangliaSmith, Maree T., Woodruff, Trent M., Wyse, Bruce D., Muralidharan, Arjun and Walther, Thomas (2013). A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Medicine, 14 (10), 1557-1568. doi: 10.1111/pme.12157 |
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2013 Journal Article C5a receptor signaling prevents folate deficiency-induced neural tube defects in miceDenny, Kerina J., Coulthard, Liam G., Jeanes, Angela, Lisgo, Steven, Simmons, David G., Callaway, Leonie K., Wlodarczyk, Bogdan, Finnell, Richard H., Woodruff, Trent M. and Taylor, Stephen M. (2013). C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. Journal of Immunology, 190 (7), 3493-3499. doi: 10.4049/jimmunol.1203072 |
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2013 Journal Article Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsiaDenny, Kerina J., Coulthard, Liam G., Finnell, Richard H., Callaway, Leonie K., Taylor, Stephen M. and Woodruff, Trent M. (2013). Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. Journal of Reproductive Immunology, 97 (2), 211-216. doi: 10.1016/j.jri.2012.11.006 |
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2013 Journal Article C5L2: a controversial receptor of complement anaphylatoxin, C5aLi, Rui, Coulthard, Liam G., Wu, M. C. L., Taylor, Stephen M. and Woodruff, Trent M. (2013). C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB Journal, 27 (3), 855-864. doi: 10.1096/fj.12-220509 |
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2013 Journal Article Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft diseasede Vries, Margreet R., Wezel, Anouk, Schepers, Abbey, van Santbrink, Peter J., Woodruff, Trent M., Niessen, Hans W. M., Hamming, Jaap F., Kuiper, Johan, Bot, Ilze and Quax, Paul H. A. (2013). Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease. Cardiovascular Research, 97 (2), 311-320. doi: 10.1093/cvr/cvs312 |
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2013 Journal Article Neural tube defects, folate, and immune modulationDenny, Kerina J., Jeanes, Angela, Fathe, Kristin, Finnell, Richard H., Taylor, Stephen M. and Woodruff, Trent M. (2013). Neural tube defects, folate, and immune modulation. Birth Defects Research Part A - Clinical and Molecular Teratology, 97 (9), 602-609. doi: 10.1002/bdra.23177 |
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2013 Conference Publication Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM)Barrett, Helen L., Mcintyre, H. David, Denny, Kerina, Woodruff, Trent, Callaway, Leonie K. and Nitert, Marloes Dekker (2013). Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). American Diabetes Association 73rd Scientific Sessions, Chicago, IL United States, 21-25 June 2013 . Arlington, VA United States: American Diabetes Association. doi: 10.2337/db13-1-387 |
