|
2018 Journal Article Chronic helminth infection perturbs the gut-brain axis, promotes neuropathology and alters behaviourGiacomin, Paul R., Kraeuter, Ann Katrin, Albornoz, Eduardo A., Jin, Shuting, Bengtsson, Mia, Gordon, Richard, Woodruff, Trent M., Urich, Tim, Sarnyai, Zoltán and Soares Magalhães, Ricardo J. (2018). Chronic helminth infection perturbs the gut-brain axis, promotes neuropathology and alters behaviour. The Journal of Infectious Diseases, 218 (9), 1511-1516. doi: 10.1093/infdis/jiy092 |
|
2018 Journal Article Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulationSkjeflo, E. W., Christiansen, D., Fure, H., Ludviksen, J. K., Woodruff, T. M., Espevik, Terje, Nielsen, E. W., Brekke, O. L. and Mollnes, T. E. (2018). Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis, 16 (5), 905-918. doi: 10.1111/jth.13979 |
|
2018 Journal Article Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced painMorgan, Michael, Deuis, Jennifer R., Woodruff, Trent M., Lewis, Richard J. and Vetter, Irina (2018). Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain. Molecular Immunology, 94, 68-74. doi: 10.1016/j.molimm.2017.12.016 |
|
2018 Journal Article Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease TreatmentHerrmann, Johannes B., Muenstermann, Marcel, Strobel, Lea, Schubert-Unkmeir, Alexandra, Woodruff, Trent M., Gray-Owen, Scott D., Klos, Andreas and Johswich, Kay O. (2018). Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment. mBio, 9 (1) e01755-17, 1-17. doi: 10.1128/mBio.01755-17 |
|
2018 Conference Publication C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activationGordon, Richard, Albornoz, Eduardo, Kanthasamy, Anumantha and Woodruff, Trent (2018). C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation. 27th International Complement Workshop (ICW), Santa Fe, NM, United States, Sep 16-20, 2018. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2018.06.247 |
|
2018 Book Chapter Inflammasomes in CNS diseasesAlbornoz, Eduardo A., Woodruff, Trent M. and Gordon, Richard (2018). Inflammasomes in CNS diseases. Inflammasomes: clinical and therapeutic implications. (pp. 41-60) edited by Mario D. Cordero and Elisabet Alcocer-Gómez. Cham, Switzerland: Springer International. doi: 10.1007/978-3-319-89390-7_3 |
|
2018 Conference Publication Auto-regulation of Th1 responses requires intracellular carboxypeptidase M-mediated complement regulationWest, Erin E., Freeley, Simon, Kolev, Martin, Niyonzima, Nathalie, Espevik, Terje, Mollnes, Tom Eirik, Lappegard, Knut, Woodruff, Trent M., Monk, Peter N. and Kemper, Claudia (2018). Auto-regulation of Th1 responses requires intracellular carboxypeptidase M-mediated complement regulation. 27th International Complement Workshop (ICW), Santa Fe, NM, United States, 16-20 September 2018. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2018.06.246 |
|
2018 Book Chapter C5aR1Coulthard, Liam G., Hawksworth, Owen A. and Woodruff, Trent M. (2018). C5aR1. The Complement FactsBook. (pp. 397-405) edited by Scott Barnum and Theresa Schein. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810420-0.00037-7 |
|
2018 Book Chapter C3aR1Coulthard, Liam G., Hawksworth, Owen A. and Woodruff, Trent M. (2018). C3aR1. The complement FactsBook. (pp. 385-396) edited by Scott Barnum and Theresa Schein. London, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-810420-0.00036-5 |
|
2018 Book Chapter C5aR2Coulthard, Liam G., Hawksworth, Owen A. and Woodruff, Trent M. (2018). C5aR2. The complement FactsBook. (pp. 407-414) edited by Scott Barnum and Theresa Schein. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810420-0.00038-9 |
|
2017 Journal Article C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritisDick, Jonathan, Gan, Poh-Yi, Ford, Sharon L., Odobasic, Dragana, Alikhan, Maliha A., Loosen, Sven H., Hall, Pam, Westhorpe, Clare L., Li, Anqi, Ooi, Joshua D., Woodruff, Trent M., Mackay, Charles R., Kitching, A Richard, Hickey, Michael J. and Holdsworth, Stephen R. (2017). C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis. Kidney International, 93 (3), 615-625. doi: 10.1016/j.kint.2017.09.018 |
|
2017 Journal Article The concise guide to pharmacology 2017/18: OverviewAlexander, Stephen P. H., Kelly, Eamonn, Marrion, Neil V., Peters, John A., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Buneman, O. Peter, Cidlowski, John A., Christopoulos, Arthur, Davenport, Anthony P., Fabbro, Doriano, Spedding, Michael, Striessnig, Jorg, Davies, Jamie A., Abbracchio, M. P., Aldrich, R., Al-Hosaini, K., Arumugam, T., V, Attali, B., Back, M., Barnes, N. M., Bathgate, R., Beart, P. M., Becirovic, E., Bettler, B., Biel, M. ... Woodruff, Trent (2017). The concise guide to pharmacology 2017/18: Overview. British Journal of Pharmacology, 174, S1-S16. doi: 10.1111/bph.13882/full |
|
2017 Journal Article Monitoring C5AR2 expression using a floxed tdtomato-C5AR2 knock-in mouseKarsten, Christian M., Wiese, Anna V., Mey, Fabian, Figge, Julia, Woodruff, Trent M., Reuter, Tom, Scurtu, Olga, Kordowski, Anna, Almeida, Larissa N., Briukhovetska, Daria, Quell, Katharina M., Sun, Jing, Ender, Fanny, Schmudde, Inken, Vollbrandt, Tillman, Laumonnier, Yves and Köhl, Jörg (2017). Monitoring C5AR2 expression using a floxed tdtomato-C5AR2 knock-in mouse. Journal of Immunology, 199 (9), 3234-3248. doi: 10.4049/jimmunol.1700710 |
|
2017 Conference Publication Targeting the C5a-C5aR1 signalling axis in diabetic kidney diseaseCoughlan, M. T., Tan, S. M., Ekinci, E. I., Snelson, M., Penfold, S. A., Higgins, G. C., Lindblom, R. S., Sourris, K. C., Thallas-Bonke, V., Jerums, G., Skene, A., Power, D. A., MacIsaac, R. J., Cooper, M. E. and Woodruff, T. M. (2017). Targeting the C5a-C5aR1 signalling axis in diabetic kidney disease. 53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Lisbon Portugal, Sep 11-15, 2017. NEW YORK: SPRINGER. |
|
2017 Journal Article New concepts on the therapeutic control of complement anaphylatoxin receptorsHawksworth, Owen A., Li, Xaria X., Coulthard, Liam G., Wolvetang, Ernst J. and Woodruff, Trent M. (2017). New concepts on the therapeutic control of complement anaphylatoxin receptors. Molecular Immunology, 89, 36-43. doi: 10.1016/j.molimm.2017.05.015 |
|
2017 Journal Article Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammationChen, Weiqiang, Foo, Suan-Sin, Zaid, Ali, Teng, Terk-Shin, Herrero, Lara J., Wolf, Stefan, Tharmarajah, Kothila, Vu, Luan D., van Vreden, Caryn, Taylor, Adam, Freitas, Joseph R., Li, Rachel W., Woodruff, Trent M., Gordon, Richard, Ojcius, David M., Nakaya, Helder I., Kanneganti, Thirumala-Devi, O’Neill, Luke A. J., Robertson, Avril A. B., King, Nicholas J., Suhrbier, Andreas, Cooper, Matthew A., Ng, Lisa F. P. and Mahalingam, Suresh (2017). Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation. Nature Microbiology, 2 (10), 1-11. doi: 10.1038/s41564-017-0015-4 |
|
2017 Journal Article The ketone body β-hydroxybutyrate does not inhibit synuclein mediated inflammasome activation in microgliaDeora, Vandana, Albornoz, Eduardo A., Zhu, Kevin, Woodruff, Trent M. and Gordon, Richard (2017). The ketone body β-hydroxybutyrate does not inhibit synuclein mediated inflammasome activation in microglia. Journal of Neuroimmune Pharmacology, 12 (4), 1-7. doi: 10.1007/s11481-017-9754-5 |
|
2017 Journal Article Serping1/C1 inhibitor affects cortical development in a cell autonomous and non-cell autonomous mannerGorelik, Anna, Sapir, Tamar, Woodruff, Trent M. and Reiner, Orly (2017). Serping1/C1 inhibitor affects cortical development in a cell autonomous and non-cell autonomous manner. Frontiers in Cellular Neuroscience, 11 169. doi: 10.3389/fncel.2017.00169 |
|
2017 Journal Article Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosisWang, Haitao A., Lee, John D., Lee, Kah Meng, Woodruff, Trent M. and Noakes, Peter G. (2017). Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. Skeletal Muscle, 7 (1) 10, 10. doi: 10.1186/s13395-017-0128-8 |
|
2017 Journal Article Developmental activities of the complement pathway in migrating neuronsGorelik, Anna , Sapir, Tamar , Haffner-Krausz, Rebecca , Olender, Tsviya , Woodruff, Trent M. and Reiner, Orly (2017). Developmental activities of the complement pathway in migrating neurons. Nature Communications, 8 (1) 15096, 15096 .1-15096 .12. doi: 10.1038/ncomms15096 |
