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2015 Journal Article Placental lipase expression in pregnancies complicated by preeclampsia: A case-control studyBarrett, Helen L., Kubala, Marta H., Scholz Romero, Katherin., Denny, Kerina J., Woodruff, Trent M., McIntyre, H.David., Callaway, Leonie K. and Dekker Nitert, Marloes. (2015). Placental lipase expression in pregnancies complicated by preeclampsia: A case-control study. Reproductive Biology and Endocrinology, 13 (1) 100, 100. doi: 10.1186/s12958-015-0098-9 |
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2015 Journal Article C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosusMahajan, Supriya D., Parikh, Neil U., Woodruff, Trent M., Jarvis, James N., Lopez, Molly, Hennon, Teresa, Cunningham, Patrick, Quigg, Richard J., Schwartz, Stanley A. and Alexander, Jessy J. (2015). C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology, 146 (1), 130-143. doi: 10.1111/imm.12489 |
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2015 Journal Article The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birthDenny, Kerina J., Coulthard, Liam G., Mantovani, Susanna, Simmons, David, Taylor, Stephen M. and Woodruff, Trent M. (2015). The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birth. American Journal of Reproductive Immunology, 74 (2), 148-155. doi: 10.1111/aji.12386 |
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2015 Journal Article Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cordKhan, Nemat, Gordon, Richard, Woodruff, Trent M. and Smith, Maree T. (2015). Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord. Pharmacology Research and Perspectives, 3 (3) e00137, 1-16. doi: 10.1002/prp2.137 |
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2015 Journal Article Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1<sup>G93A</sup> mouse model of amyotrophic lateral sclerosisLee, Jia Y., Lee, John D., Phipps, Simon, Noakes, Peter G. and Woodruff, Trent M. (2015). Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis. Journal of Neuroinflammation, 12 (1) 90, 90. doi: 10.1186/s12974-015-0310-z |
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2015 Journal Article A commentary on: "NF kappa B-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease". A cautionary note regarding C3aRWoodruff, Trent M. and Tenner, Andrea J. (2015). A commentary on: "NF kappa B-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease". A cautionary note regarding C3aR. Frontiers in Immunology, 6 (MAY) 220, 220. doi: 10.3389/fimmu.2015.00220 |
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2015 Journal Article The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injuryBrennan, Faith H., Gordon, Richard, Lao, Hong W., Biggins, Patrick J., Taylor, Stephen M., Franklin, Robin J. M., Woodruff, Trent M. and Ruitenberg, Marc J. (2015). The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury. Journal of Neuroscience, 35 (16), 6517-6531. doi: 10.1523/JNEUROSCI.5218-14.2015 |
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2015 Journal Article Is the complement activation product C3a a proinflammatory molecule? Re-evaluating the evidence and the mythCoulthard, Liam G. and Woodruff, Trent M. (2015). Is the complement activation product C3a a proinflammatory molecule? Re-evaluating the evidence and the myth. Journal of Immunology, 194 (8), 3542-3548. doi: 10.4049/jimmunol.1403068 |
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2015 Journal Article A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy modelsBenson, Melissa J, Thomas, Nicola K, Talwar, Sahil, Hodson, Mark P, Lynch, Joseph W, Woodruff, Trent M and Borges, Karin (2015). A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models. Neurobiology of Disease, 76, 87-97. doi: 10.1016/j.nbd.2015.02.004 |
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2015 Journal Article Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent mannerJain, Umang, Cao, Qi, Thomas, Nikhil A, Woodruff, Trent M, Schwaeble, Wilhelm J, Stover, Cordula M and Stadnyk, Andrew W (2015). Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent manner. Journal of Immunology, 194 (7), 3414-3421. doi: 10.4049/jimmunol.1401814 |
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2015 Conference Publication Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegenerationKumar, Vinod, Lee, John, Noakes, Peter and Woodruff, Trent (2015). Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration. 8th International Conference on Complement Therapeutics, Chania, Crete, Greece, 1-6 January 2015. |
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2015 Conference Publication Peripheral immune complement activation in neurodegenerative diseaseMantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188 |
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2015 Conference Publication Investigating the role of C5a-CD88 signalling axis in diabetic nephropathyTan, S. M., Nguyen, T. V., Woodruff, T. M. and Coughlan, M. T. (2015). Investigating the role of C5a-CD88 signalling axis in diabetic nephropathy. 51st Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Canberra, Australia, 7-9 September, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12543 |
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2015 Conference Publication Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathwayAlbornoz, E., Deora, V., Robertson, B. A., Cooper, M. A., Schroder, K., Woodruff, T. M. and Gordon, R. (2015). Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley-Blackwell. |
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2015 Conference Publication Unexpected activities of the complement pathway in migrating neuronsReiner, O., Gorelik, A., Sapir, T., Bialas, A. R., Stevens, B., Woodruff, T. M. and Haffner-Krausz, R. (2015). Unexpected activities of the complement pathway in migrating neurons. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13185 |
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2014 Journal Article Derivation of ligands for the complement C3a receptor from the C-terminus of C5aHalai, Reena, Bellows-Peterson, Meghan L., Branchett, Will, Smadbeck, James, Kieslich, Chris A., Croker, Daniel E., Cooper, Matthew A., Morikis, Dimitrios, Woodruff, Trent M., Floudas, Christodoulos A. and Monk, Peter N. (2014). Derivation of ligands for the complement C3a receptor from the C-terminus of C5a. European Journal of Pharmacology, 745, 176-181. doi: 10.1016/j.ejphar.2014.10.041 |
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2014 Journal Article Brief report: Complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2Hawksworth, Owen A., Coulthard, Liam G., Taylor, Stephen M., Wolvetang, Ernst J. and Woodruff, Trent M. (2014). Brief report: Complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2. Stem Cells, 32 (12), 3278-3284. doi: 10.1002/stem.1801 |
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2014 Journal Article Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methodsKhan, Nemat, Woodruff, Trent M. and Smith, Maree T. (2014). Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. Pharmacology Biochemistry and Behavior, 126, 13-27. doi: 10.1016/j.pbb.2014.09.003 |
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2014 Journal Article Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosisGu H., Mickler E.A., Cummings O.W., Sandusky G.E., Weber D.J., Gracon A., Woodruff T., Wilkes D.S. and Vittal R. (2014). Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis. FASEB Journal, 28 (10), 4223-4234. doi: 10.1096/fj.13-247650 |
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2014 Journal Article Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient bloodMantovani, S., Gordon, R., Macmaw, J. K., Plfluger, C. M., Henderson, R. D., Noakes, P. G., McCombe, P. A. and Woodruff, T. M. (2014). Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood. Journal of Neuroimmunology, 276 (1-2), 213-218. doi: 10.1016/j.jneuroim.2014.09.005 |
