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2025 Conference Publication Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptorsClark, Richard, Dent, Joshua, Gorman, Declan, Li, Xaria, Wu, Xiaosa, Cui, Cedric, Fung, Jenny, Lee, John, Rosengren, Johan and Woodruff, Trent (2025). Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptors. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153001 |
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2025 Conference Publication Investigating the role of neuronally-expressed C5aR1 in motor neuron diseaseRisby-Jones, Grace, Woodruff, Trent M., Fung, Jenny N. and Lee, John D. (2025). Investigating the role of neuronally-expressed C5aR1 in motor neuron disease. 30th International Complement Workshop - ICW2025, Brisbane, QLD Australia, 14-19 September 2025. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153079 |
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2025 Conference Publication The enigmatic role of C5aR2 in diabetic kidney diseaseTrambas, Inez, Laskowski, Adrienne, Khayyira, Amalia, Sharma, Arpeeta, Gan, Poh Yi, Woodruff, Trent, Coughlan, Melinda and Tan, Sih Min (2025). The enigmatic role of C5aR2 in diabetic kidney disease. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153007 |
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2025 Conference Publication Role of complement components 3A (C3A) and 5A (C5A) in the acute-to-chronic pain transition in a mouse model of neuropathic painVygonskaya, Marina, Smith, Maree, Woodruff, Trent and Han, Felicity (2025). Role of complement components 3A (C3A) and 5A (C5A) in the acute-to-chronic pain transition in a mouse model of neuropathic pain. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152963 |
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2025 Conference Publication Exploring the role of the terminal complement pathway in the DSS-induced colitis model of inflammatory bowel diseaseCui, Cedric, Lerskiatiphanich, Titaya, Lee, John and Woodruff, Trent (2025). Exploring the role of the terminal complement pathway in the DSS-induced colitis model of inflammatory bowel disease. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152997 |
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2025 Conference Publication Microglial Complement C5aR1 signalling drives inflammasome mediated neuropathology in Parkinson’s diseaseAlbornoz, Eduardo, Gordon, Richard, Javed, Ibrahim, Bodea, Gabriela, Kumar, Vinod, Cui, Cedric, Aguado, Julio, Mardon, Karine, Bhalla, Rajiv, Cowin, Gary and Woodruff, Trent (2025). Microglial Complement C5aR1 signalling drives inflammasome mediated neuropathology in Parkinson’s disease. 30th International Complement Workshop 2025, Brisbane, QLD Australia, 14-19 September 2025. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152955 |
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2025 Conference Publication Complement C3a receptor signalling mitigates motor neuron degeneration by modulating neurotoxic astrocytesJulianisya, Alana R., Fung, Jenny N.T., Lerskiatiphanich, Titaya, Woodruff, Trent M. and Lee, John D. (2025). Complement C3a receptor signalling mitigates motor neuron degeneration by modulating neurotoxic astrocytes. 30th International Complement Workshop - ICW2025, Brisbane, QLD Australia, 14-19 September 2025. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153081 |
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2025 Conference Publication A conserved molecular mechanism orchestrates diverse ligand recognition at the complement anaphylatoxin receptor C3aRMishra, Sudha, Dalal, Annu, Yadav, Manish Kumar, Yadav, Ravi, Ganguly, Manisankar, Lee, John, Banerjee, Ramanuj, Woodruff, Trent, Gati, Cornelius and Shukla, Arun Kumar (2025). A conserved molecular mechanism orchestrates diverse ligand recognition at the complement anaphylatoxin receptor C3aR. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152978 |
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2025 Conference Publication A detrimental role for complement C5aR1 activation in Huntington’s diseaseMarallag, Jianina, Fung, Jenny, Lee, John and Woodruff, Trent (2025). A detrimental role for complement C5aR1 activation in Huntington’s disease. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153080 |
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2025 Conference Publication Complement C5aR1 modulates excitatory synaptic transmission in cortical pyramidal neurons via a calcium-independent mechanismParker, Sandra, Bellingham, Mark and Woodruff, Trent (2025). Complement C5aR1 modulates excitatory synaptic transmission in cortical pyramidal neurons via a calcium-independent mechanism. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153054 |
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2025 Conference Publication Motor neuron disease C9orf72 dipeptides mediate neurotoxicity in human brain organoids through activation of C5aR1Cao, Yuzhihan, Pietrogrande, Giovanni, Pars, Selin, Clark, Richard, Wolvetang, Ernst, Woodruff, Trent and Albornoz, Eduardo (2025). Motor neuron disease C9orf72 dipeptides mediate neurotoxicity in human brain organoids through activation of C5aR1. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153008 |
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2025 Conference Publication Investigating complement receptor C3aR1 signalling in metabolic dysfunction in the R6/1 mouse model of Huntington's diseaseLerskiatiphanich, Titaya, McDonald, Tanya, Cui, Cedric, Fung, Jenny, Woodruff, Trent and Lee, John (2025). Investigating complement receptor C3aR1 signalling in metabolic dysfunction in the R6/1 mouse model of Huntington's disease. 30th International Complement Workshop - ICW2025, Brisbane, QLD Australia, 14-19 September 2025. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153064 |
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2025 Conference Publication The complement C3a receptor regulates the tumour microenvironmentRolfe, Barbara, Sonderegger, Stefan, Panagides, Nadya, McGirr, Crystal, Nabizadeh, Jamileh, Li, Xaria and Woodruff, Trent (2025). The complement C3a receptor regulates the tumour microenvironment. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153021 |
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2025 Conference Publication Live-cell single-molecule imaging of a new fluorescent C5a receptor antagonist reveals the heterogeneous spatiotemporal dynamics of C5aR1 at the plasma membraneSun, Jinda, Parker, Sandra, Lee, Jonathan, Gorman, Declan, Li, Xaria, Albornoz Balmaceda, Eduardo, Bellingham, Mark, Clark, Richard, Woodruff, Trent and Padmanabhan, Pranesh (2025). Live-cell single-molecule imaging of a new fluorescent C5a receptor antagonist reveals the heterogeneous spatiotemporal dynamics of C5aR1 at the plasma membrane. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152969 |
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2024 Conference Publication Deciphering complement-dependent macrophage phenotypes in human rheumatoid arthritis using combined computationalexperimental single-cell omicsVargas, Juan, Mantel, Ian, Inamo, Jun, Banda, Nirmal, Jonsson, Anna Helena, Wei, Kevin, Rao, Deepak, Goodman, Susan, Deane, Kevin, Seifert, Jennifer, Anolik, Jennifer, Brenner, Michael, Raychaudhuri, Soumya, Woodruff, Trent, Holers, Michael, Donlin, Laura and Zhang, Fan (2024). Deciphering complement-dependent macrophage phenotypes in human rheumatoid arthritis using combined computationalexperimental single-cell omics. ACR Convergence 2024, Washington, DC, United States, 15-19 November 2024. Hoboken, NJ 07030 United States: John Wiley & Sons. doi: 10.1002/art.42992 |
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2024 Conference Publication Colon-targeted complement C5aR1 inhibition using pH-sensitive nanoparticles ameliorates experimental colitisCui, Cedric, Lee, John and Woodruff, Trent (2024). Colon-targeted complement C5aR1 inhibition using pH-sensitive nanoparticles ameliorates experimental colitis. 19th European Meeting on Complement in Human Diseases, Lübeck, Germany, 2-6 September 2024. Weinheim, Germany: Wiley-VCH. |
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2024 Conference Publication Temporal characterisation of renal immunophenotype with mitochondrial kinetic profile in a preclinical model of diabetic kidney diseaseTrambas, Inez, Laskowski, Adrienne, Khayyira, Amalia, Sharma, Arpeeta, Woodruff, Trent, Coughlan, Melinda and Tan, Sih Min (2024). Temporal characterisation of renal immunophenotype with mitochondrial kinetic profile in a preclinical model of diabetic kidney disease. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA, Australia, 31 August–4 September 2024. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14360 |
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2024 Conference Publication Dual inhibition of complement C5a receptor 1 and 2 in diabetic kidney diseaseTan, Sih Min, Trambas, Inez, Laskowski, Adrienne, Khayyira, Amalia, Sharma, Arpeeta, Woodruff, Trent and Coughlan, Melinda (2024). Dual inhibition of complement C5a receptor 1 and 2 in diabetic kidney disease. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA, Australia, 31 August–4 September 2024. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14361 |
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2024 Conference Publication Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptorsClark, Richard, Gorman, Declan, Li, Xaria, Dent, Joshua, Cui, Cedric, Lee, Han Siean, Fung, Jenny, Lee, John, Rosengren, K. Johan and Woodruff, Trent (2024). Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptors. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Conference Publication C5aR-antagonism alone or in combination with MEK inhibition durably alters the plexiform neurofibroma tumor micro-environmentAhmari, Niousha, Perrino, Melissa, Pundavela, Jay, Szabo, Sara, Woodruff, Trent, Dombi, Eva, Kim, Mi-Ok, Köhl, Jörg, Wu, Jianqiang and Ratner, Nancy (2024). C5aR-antagonism alone or in combination with MEK inhibition durably alters the plexiform neurofibroma tumor micro-environment. ASPET 2024 Annual Meeting, Arlington, VA United States, 16-19 May 2024. Rockville, MD United States: American Society for Pharmacology and Experimental Therapeutics. doi: 10.1124/jpet.249.988670 |
