2024 Conference Publication Deciphering complement-dependent macrophage phenotypes in human rheumatoid arthritis using combined computationalexperimental single-cell omicsVargas, Juan, Mantel, Ian, Inamo, Jun, Banda, Nirmal, Jonsson, Anna Helena, Wei, Kevin, Rao, Deepak, Goodman, Susan, Deane, Kevin, Seifert, Jennifer, Anolik, Jennifer, Brenner, Michael, Raychaudhuri, Soumya, Woodruff, Trent, Holers, Michael, Donlin, Laura and Zhang, Fan (2024). Deciphering complement-dependent macrophage phenotypes in human rheumatoid arthritis using combined computationalexperimental single-cell omics. ACR Convergence 2024, Washington, DC, United States, 15-19 November 2024. Hoboken, NJ 07030 United States: John Wiley & Sons. doi: 10.1002/art.42992 |
2024 Conference Publication Colon-targeted complement C5aR1 inhibition using pH-sensitive nanoparticles ameliorates experimental colitisCui, Cedric, Lee, John and Woodruff, Trent (2024). Colon-targeted complement C5aR1 inhibition using pH-sensitive nanoparticles ameliorates experimental colitis. 19th European Meeting on Complement in Human Diseases, Lübeck, Germany, 2-6 September 2024. Weinheim, Germany: Wiley-VCH. |
2024 Conference Publication Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptorsClark, Richard, Gorman, Declan, Li, Xaria, Dent, Joshua, Cui, Cedric, Lee, Han Siean, Fung, Jenny, Lee, John, Rosengren, K. Johan and Woodruff, Trent (2024). Development of novel peptide ligands with improved selectivity and pharmacological properties for complement system receptors. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
2024 Conference Publication Temporal characterisation of renal immunophenotype with mitochondrial kinetic profile in a preclinical model of diabetic kidney diseaseTrambas, Inez, Laskowski, Adrienne, Khayyira, Amalia, Sharma, Arpeeta, Woodruff, Trent, Coughlan, Melinda and Tan, Sih Min (2024). Temporal characterisation of renal immunophenotype with mitochondrial kinetic profile in a preclinical model of diabetic kidney disease. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA, Australia, 31 August–4 September 2024. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14360 |
2024 Conference Publication Dual inhibition of complement C5a receptor 1 and 2 in diabetic kidney diseaseTan, Sih Min, Trambas, Inez, Laskowski, Adrienne, Khayyira, Amalia, Sharma, Arpeeta, Woodruff, Trent and Coughlan, Melinda (2024). Dual inhibition of complement C5a receptor 1 and 2 in diabetic kidney disease. 59th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Adelaide, SA, Australia, 31 August–4 September 2024. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14361 |
2024 Conference Publication C5aR-antagonism alone or in combination with MEK inhibition durably alters the plexiform neurofibroma tumor micro-environmentAhmari, Niousha, Perrino, Melissa, Pundavela, Jay, Szabo, Sara, Woodruff, Trent, Dombi, Eva, Kim, Mi-Ok, Köhl, Jörg, Wu, Jianqiang and Ratner, Nancy (2024). C5aR-antagonism alone or in combination with MEK inhibition durably alters the plexiform neurofibroma tumor micro-environment. ASPET 2024 Annual Meeting, Arlington, VA United States, 16-19 May 2024. Rockville, MD United States: American Society for Pharmacology and Experimental Therapeutics. doi: 10.1124/jpet.249.988670 |
2024 Conference Publication Targeting C5aR1 to improve radiotherapy in tumours with immunosuppressive microenvironmentsBeach, Callum, MacLean, David, Majorova, Dominika, Valbuena, Gabriel N., Damavandi, Mahnaz Darvish, Suwa, Tatsuya, Easton, Alistair, Hillson, Lily V.S., McCulloch, Ashley K., McMahon, Ross K., Pennel, Kathryn, Edwards, Joanne, O’Cathail, Sean M., Roxburgh, Campbell S., Moon, Eui Jung, Guglietta, Silvia, Krieg, Carsten, Woodruff, Trent M., Maughan, Tim, Buczacki, Simon J.A., Leedham, Simon J., Giaccia, Amato J., Clark, Heather and Olcina, Monica M. (2024). Targeting C5aR1 to improve radiotherapy in tumours with immunosuppressive microenvironments. ESTRO meets Asia 2024, Kuala Lumpur, Malaysia, 23-25 August 2024. Shannon, Ireland: Elsevier. doi: 10.1016/s0167-8140(24)01225-8 |
2024 Conference Publication Dysregulation of T cell intrinsic C5aR2 activation causes uncontrolled inflammatory Th responses and autoinflammatory syndromeWest, Erin, Merle, Nicolas, Bibby, Jack, Singh, Parul, Rahman, Jubayer, Morgensen, Trine Hyrup, Woodruff, Trent, Monk, Peter, Christiansen, Mette and Kemper, Claudia (2024). Dysregulation of T cell intrinsic C5aR2 activation causes uncontrolled inflammatory Th responses and autoinflammatory syndrome. Annual Meeting of the American Association of Immunologists (IMMUNOLOGY), Chicago, IL, United States, 3-7 May 2024. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.212.supp.0526.5407 |
2023 Conference Publication T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunityMerle, Nicolas S., Freeley, Simon, Bibby, Jack, Singh, Parul, Rahman, Jubayer, Kolev, Martin, Niyonzima, Nathalie, Morgensen, Trine Hyrup, Woodruff, Trent M., Monk, Peter, Lappegard, Knut, Espevik, Terje, Mollness, Tom Eirik, Christiansen, Mette, West, Erin E. and Kemper, Claudia (2023). T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.64.15 |
2023 Conference Publication Dietary resistant starch alters gut microbiota, microbially produced metabolites and albuminuria in diabetic miceSnelson, M., Tan, S. M., Kumar, V., Woodruff, T. and Coughlan, M. T. (2023). Dietary resistant starch alters gut microbiota, microbially produced metabolites and albuminuria in diabetic mice. 46th Annual Scientific Meeting of the Nutrition Society of Australia, Perth, WA, Australia, 29 November – 2 December 2022. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/s0029665123001921 |
2022 Conference Publication Immunoregulatory role for complement receptors in murine breast cancerRolfe, Barbara, Sonderegger, Stefan, McGirr, Crystal and Woodruff, Trent (2022). Immunoregulatory role for complement receptors in murine breast cancer. 28th Virtual International Complement Workshop (ICW) of the International-Complement-Society (ICS), Virtual, 6-10 December 2021. Oxford, United Kingdom: Elsevier. |
2022 Conference Publication Identification of potent small peptides targeting human C3a receptorDeerain, Nick, Kumar, Vinod, Clark, Richard and Woodruff, Trent (2022). Identification of potent small peptides targeting human C3a receptor. ICW – 2021 Virtual Workshop of the International Complement Society (ICS), Virtual, 7-10 December 2021. Oxford, United Kingdom: Elsevier. |
2021 Conference Publication Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent DementiaTran, Shirley, Woodruff, Trent, Kumar, Vinod, Smith, A. Ian, Rajapakse, Niwanthi and Kuruppu, Sanjaya (2021). Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent Dementia. Experimental Biology Meeting EB 2021, Online, 27–30 April 2022. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.2021.35.s1.01628 |
2020 Conference Publication T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunityWest, Erin E., Freeley, Simon, Kolev, Martin, Niyonzima, Nathalie, Mogensen, Trine Hyrup, Woodruff, Trent M., Monk, Peter, Lappegard, Knut, Espevik, Terje, Mollnes, Tom Eirik, Christiansen, Mette and Kemper, Claudia (2020). T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.150.23 |
2020 Conference Publication Increased complement component 5a signalling drives severe asthma pathogenesisKim, R., Brown, A., Carroll, O., Hsu, A., Baines, K., Pathinayake, P., Kemper, C., Woodruff, T., Adcock,, Gibson, P., Wark, P., Horvat, J. and Hansbro, P. (2020). Increased complement component 5a signalling drives severe asthma pathogenesis. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health and Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777 |
2019 Conference Publication Complement Inhibition: A Possible Therapeutic Strategy For Controlling Cobra EnvenomationSilva-de-Franca, Felipe, Villas-Boas, Isadora, Cogliati, Bruno, Woodruff, Trent, da-Silva-Reis, Edimara, Lambris, John and Tambourgi, Denise (2019). Complement Inhibition: A Possible Therapeutic Strategy For Controlling Cobra Envenomation. 17th European Meeting on Complement in Human Disease (EMCHD), Madrid, Spain, 2019. Oxford, United Kingdom: Elsevier . |
2019 Conference Publication Bacterial-induced il-8 release is dependent on c5a-05ar1 and thrombin-dependent activation of platelets in human whole bloodQuang Huy Quach,, Johnson, Christina, Lau, Corinna, Woodruff, Trent M., Pischke, Soren E., Mollnes, Tom Eirik and Nilsson, Per H. (2019). Bacterial-induced il-8 release is dependent on c5a-05ar1 and thrombin-dependent activation of platelets in human whole blood. 17th European Meeting on Complement in Human Disease (EMCHD), Madrid, Spain, 2019. Oxford, United Kingdom: Elsevier . |
2019 Conference Publication Complement alone drives efficacy of a chimeric anti-gonococcal monoclonal antibodyBeurskens, Frank, de Kreuk, Bart-Jan, Roza, Marcel, Zheng, Bo, DeOliveira, Rosane, Shaughnessy, Jutamas, Taylors, Ronald, Botto, Marina, He, Xianbao, Ingalls, Robin, Woodruff, Trent, Song, Wen-Chao, Schuurman, Janine, Rice, Peter and Ram, Sanjay (2019). Complement alone drives efficacy of a chimeric anti-gonococcal monoclonal antibody. 17th European Meeting on Complement in Human Disease (EMCHD), Madrid, Spain, 2019. Oxford, United Kingdom: Elsevier . |
2019 Conference Publication Deciphering key roles for complement peptide receptors in brain developmentWoodruff, T., Hawksworth, O., Lee, J. and Coulthard, L. (2019). Deciphering key roles for complement peptide receptors in brain development. Joint Meeting of the International Society for Neurochemistry and American Society for Neurochemistry (ISN-ASN), Montreal, Canada, 4-8 August 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. |
2019 Conference Publication Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanomaNabizadeh, J., Manthey, H., Panagides, N., Steyn, F., Lee, J., Li, X., Woodruff, T. and Rolfe, B. (2019). Complement C5a receptors, C5aR1 and C5aR2, mediate opposing pathologies in a mouse model of melanoma. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October 2019. Weinheim, Germany: Wiley. |