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2020 Journal Article The peripheral immune system and amyotrophic lateral sclerosisMcCombe, Pamela A., Lee, John D., Woodruff, Trent M. and Henderson, Robert D. (2020). The peripheral immune system and amyotrophic lateral sclerosis. Frontiers in Neurology, 11 279, 279. doi: 10.3389/fneur.2020.00279 |
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2020 Journal Article The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosisMcDonald, Tanya S., McCombe, Pamela A., Woodruff, Trent M. and Lee, John D. (2020). The potential interplay between energy metabolism and innate complement activation in amyotrophic lateral sclerosis. The FASEB Journal, 34 (6) fj.201901781, 7225-7233. doi: 10.1096/fj.201901781 |
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2020 Journal Article Complement: bridging the innate and adaptive immune systems in sterile inflammationLo, Martin W. and Woodruff, Trent M. (2020). Complement: bridging the innate and adaptive immune systems in sterile inflammation. Journal of Leukocyte Biology, 108 (1) JLB.3MIR0220-270R, 339-351. doi: 10.1002/jlb.3mir0220-270r |
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2020 Journal Article Low-fouling fluoropolymers for bioconjugation and in vivo trackingFu, Changkui, Demir, Baris, Alcantara, Sheilajen, Kumar, Vinod, Han, Felicity, Kelly, Hannah, Tan, Xiao, Yu, Ye, Xu, Weizhi, Zhao, Jiacheng, Zhang, Cheng, Peng, Hui, Boyer, Cyrille, Woodruff, Trent, Kent, Stephen, Searles, Debra and Whittaker, Andrew (2020). Low-fouling fluoropolymers for bioconjugation and in vivo tracking. Angewandte Chemie International Edition, 59 (12), 4729-4735. doi: 10.1002/anie.201914119 |
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2020 Journal Article Editorial: The Role of Complement in TumorsRolfe, Barbara E., Pio, Ruben, Woodruff, Trent M., Markiewski, Maciej M. and Manthey, Helga D. (2020). Editorial: The Role of Complement in Tumors. Frontiers in Immunology, 11 139, 139. doi: 10.3389/fimmu.2020.00139 |
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2020 Journal Article Low‐fouling fluoropolymers for bioconjugation and in vivo trackingFu, Changkui, Demir, Baris, Alcantara, Sheilajen, Kumar, Vinod, Han, Felicity, Kelly, Hannah G., Tan, Xiao, Yu, Ye, Xu, Weizhi, Zhao, Jiacheng, Zhang, Cheng, Peng, Hui, Boyer, Cyrille, Woodruff, Trent M., Kent, Stephen J., Searles, Debra J. and Whittaker, Andrew K. (2020). Low‐fouling fluoropolymers for bioconjugation and in vivo tracking. Angewandte Chemie, 132 (12), 4759-4765. doi: 10.1002/ange.201914119 |
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2020 Journal Article The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteinsDeora, Vandana, Lee, John D., Albornoz, Eduardo A., McAlary, Luke, Jagaraj, Cyril J., Robertson, Avril A. B., Atkin, Julie D, Cooper, Matthew A., Schroder, Kate, Yerbury, Justin J., Gordon, Richard and Woodruff, Trent M. (2020). The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins. Glia, 68 (2) glia.23728, 407-421. doi: 10.1002/glia.23728 |
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2020 Journal Article Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in miceKumar, Vinod, Lee, John D., Clark, Richard J., Noakes, Peter G., Taylor, Stephen M. and Woodruff, Trent M. (2020). Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice. ACS Omega, 5 (5) acsomega.9b03735, 2345-2354. doi: 10.1021/acsomega.9b03735 |
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2020 Journal Article Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosisArbore, Giuseppina, Ong, Voon H., Costantini, Benedetta, Denton, Christopher P., Abraham, David, Placais, Leo, Blighe, Kevin, Mitchell, Lynne, Ellis, Richard, Heck, Susanne, Nocerino, Paola, Woodruff, Trent M., Kordasti, Shahram, Kemper, Claudia and Hourcade, Dennis E. (2020). Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosis. Cellular & Molecular Immunology, 17 (9), 1010-1013. doi: 10.1038/s41423-019-0360-8 |
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2020 Conference Publication Increased complement component 5a signalling drives severe asthma pathogenesisKim, R., Brown, A., Carroll, O., Hsu, A., Baines, K., Pathinayake, P., Kemper, C., Woodruff, T., Adcock,, Gibson, P., Wark, P., Horvat, J. and Hansbro, P. (2020). Increased complement component 5a signalling drives severe asthma pathogenesis. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health and Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777 |
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2019 Journal Article Commentary: Beyond C4: analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls by Holland, J. F., Cosgrove, D., Whitton, L., Harold, D., Corvin, A., Gill, M., et al. (2019). Genes Brain Behav. 18:e12602Coulthard, Liam G. and Woodruff, Trent M. (2019). Commentary: Beyond C4: analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls by Holland, J. F., Cosgrove, D., Whitton, L., Harold, D., Corvin, A., Gill, M., et al. (2019). Genes Brain Behav. 18:e12602. Frontiers in Immunology, 10 2853, 2853. doi: 10.3389/fimmu.2019.02853 |
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2019 Journal Article The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptorsAlexander, Stephen P. H., Christopoulos, Arthur, Davenport, Anthony P., Kelly, Eamonn, Mathie, Alistair, Peters, John A., Veale, Emma L., Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Pawson, Adam J., Sharman, Joanna L., Southan, Christopher, Davies, Jamie A., Abbracchio, Maria P., Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Catt, Kevin J. ... Yao, Chengcan (2019). The Concise Guide to Pharmacology 2019/20: G protein‐coupled receptors. British Journal of Pharmacology, 176 (S1), S21-S141. doi: 10.1111/bph.14748 |
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2019 Journal Article Complement C5a induces renal injury in diabetic kidney disease by disrupting mitochondrial metabolic agilityTan, Sih Min, Ziemann, Mark, Thallas-Bonke, Vicki, Snelson, Matthew, Kumar, Vinod, Laskowski, Adrienne, Nguyen, Tuong-Vi, Huynh, Kevin, Clarke, Michele V., Libianto, Renata, Baker, Scott T., Skene, Alison, Power, David A., MacIsaac, Richard J., Henstridge, Darren C., Wetsel, Rick A., El-Osta, Assam, Meikle, Peter J., Wilson, Scott G., Forbes, Josephine M., Cooper, Mark E., Ekinci, Elif I., Woodruff, Trent M. and Coughlan, Melinda T. (2019). Complement C5a induces renal injury in diabetic kidney disease by disrupting mitochondrial metabolic agility. Diabetes, 69 (1), 83-98. doi: 10.2337/db19-0043 |
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2019 Journal Article Complement dysregulation in the central nervous system during development and diseaseLee, John D., Coulthard, Liam G. and Woodruff, Trent M. (2019). Complement dysregulation in the central nervous system during development and disease. Seminars in Immunology, 45 101340, 101340. doi: 10.1016/j.smim.2019.101340 |
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2019 Journal Article Complement peptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology DatabaseCianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2019). Complement peptide receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2019 (4). doi: 10.2218/gtopdb/f5/2019.4 |
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2019 Journal Article Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14Skjeflo, E. W., Christiansen, D., Landsem, A., Stenvik, J., Woodruff, T. M., Espevik, T., Nielsen, E. W. and Mollnes, T. E. (2019). Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology, 112, 131-139. doi: 10.1016/j.molimm.2019.03.014 |
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2019 Journal Article Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infectionsMuenstermann, Marcel, Strobel, Lea, Klos, Andreas, Wetsel, Rick A., Woodruff, Trent M., Köhl, Jörg and Johswich, Kay O. (2019). Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections. Virulence, 10 (1), 677-694. doi: 10.1080/21505594.2019.1640035 |
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2019 Journal Article C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanomaNabizadeh, Jamileh A., Manthey, Helga D., Panagides, Nadya, Steyn, Frederik J., Lee, John D., Li, Xaria X., Akhir, Fazrena N. M., Chen, Weiyu, Boyle, Glen M., Taylor, Stephen M., Woodruff, Trent M. and Rolfe, Barbara E. (2019). C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma. FASEB Journal, 33 (10), fj201800980RR-11071. doi: 10.1096/fj.201800980rr |
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2019 Journal Article Cholesterol crystals induce coagulation activation through complement-dependent expression of monocytic tissue factorGravastrand, Caroline S., Steinkjer, Bjørg, Halvorsen, Bente, Landsem, Anne, Skjelland, Mona, Jacobsen, Eva Astrid, Woodruff, Trent M., Lambris, John D., Mollnes, Tom E., Brekke, Ole-Lars, Espevik, Terje and Rokstad, Anne Mari A. (2019). Cholesterol crystals induce coagulation activation through complement-dependent expression of monocytic tissue factor. Journal of Immunology, 203 (4), 853-863. doi: 10.4049/jimmunol.1900503 |
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2019 Journal Article Revisiting the role of the innate immune complement system in ALSParker, Sandra E., Hanton, Angela M., Stefanou, Stephen N., Noakes, Peter G., Woodruff, Trent M. and Lee, John D. (2019). Revisiting the role of the innate immune complement system in ALS. Neurobiology of Disease, 127, 223-232. doi: 10.1016/j.nbd.2019.03.003 |
