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2021 Journal Article The concise guide to pharmacology 2021/22: G protein‐coupled receptorsAlexander, Stephen PH, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo ... Ye, Richard D. (2021). The concise guide to pharmacology 2021/22: G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1), S27-S156. doi: 10.1111/bph.15538 |
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2021 Journal Article Complement peptide receptors in GtoPdb v.2021.3Cianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xaria X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2021). Complement peptide receptors in GtoPdb v.2021.3. IUPHAR/BPS Guide to Pharmacology CITE, 2021 (3), 1-13. doi: 10.2218/gtopdb/f5/2021.3 |
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2021 Journal Article The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and painWarwick, Charles A., Keyes, Alex L., Woodruff, Trent M. and Usachev, Yuriy M. (2021). The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain. Journal of Biological Chemistry, 297 (3) 101085, 101085. doi: 10.1016/J.JBC.2021.101085 |
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2021 Journal Article Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosisMcGill, R.B., Steyn, F.J., Ngo, S.T., Thorpe, K.A., Heggie, S., Henderson, R.D., Mccombe, P.A. and Woodruff, T.M. (2021). Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1964531 |
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2021 Journal Article Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanismMcDonald, Tanya S., Kumar, Vinod, Fung, Jenny N., Woodruff, Trent M. and Lee, John D. (2021). Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism. The FASEB Journal, 35 (7) e21707, e21707. doi: 10.1096/fj.202002450r |
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2021 Conference Publication Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent DementiaTran, Shirley, Woodruff, Trent, Kumar, Vinod, Smith, A. Ian, Rajapakse, Niwanthi and Kuruppu, Sanjaya (2021). Stimulating the Activity of NEP and ACE2: A Unique Approach to Prevent Dementia. Experimental Biology Meeting EB 2021, Online, 27–30 April 2022. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.2021.35.s1.01628 |
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2021 Journal Article C5a-C5aR1 axis activation drives envenomation immunopathology by the snake Naja annuliferaSilva de França, Felipe, Villas-Boas, Isadora Maria, Cogliati, Bruno, Woodruff, Trent M., Reis, Edimara da Silva, Lambris, John D. and Tambourgi, Denise V. (2021). C5a-C5aR1 axis activation drives envenomation immunopathology by the snake Naja annulifera. Frontiers in Immunology, 12 652242, 1-16. doi: 10.3389/fimmu.2021.652242 |
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2021 Journal Article The “C3aR Antagonist” SB290157 is a partial C5aR2 agonistLi, Xaria X., Kumar, Vinod, Clark, Richard J., Lee, John D. and Woodruff, Trent M. (2021). The “C3aR Antagonist” SB290157 is a partial C5aR2 agonist. Frontiers in Pharmacology, 11 591398, 591398. doi: 10.3389/fphar.2020.591398 |
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2021 Journal Article An immunoregulatory role for complement receptors in murine models of breast cancerAkhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002 |
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2021 Journal Article Chemical synthesis and characterisation of the complement C5 inhibitory peptide zilucoplanGorman, Declan M., Lee, John, Payne, Colton D., Woodruff, Trent M. and Clark, Richard J. (2021). Chemical synthesis and characterisation of the complement C5 inhibitory peptide zilucoplan. Amino Acids, 53 (1), 143-147. doi: 10.1007/s00726-020-02921-5 |
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2020 Journal Article TDP-43 Puts the STING in ALSLee, John D. and Woodruff, Trent M. (2020). TDP-43 Puts the STING in ALS. Trends in Neurosciences, 44 (2), 81-82. doi: 10.1016/j.tins.2020.12.001 |
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2020 Journal Article Tissue-type plasminogen activator and tenecteplase-mediated increase in blood brain barrier permeability involves cell intrinsic complementKeragala, Charithani B., Woodruff, Trent M., Liu, Zikou, Niego, Be'eri, Ho, Heidi, McQuilten, Zoe and Medcalf, Robert L. (2020). Tissue-type plasminogen activator and tenecteplase-mediated increase in blood brain barrier permeability involves cell intrinsic complement. Frontiers in Neurology, 11 577272, 1-12. doi: 10.3389/fneur.2020.577272 |
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2020 Journal Article Complement peptide receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology DatabaseCianciulli, Antonia, Coulthard, Liam, Hawksworth, Owen, Lee, John D., Li, Xiang X., Mitolo, Vincenzo, Monk, Peter, Panaro, Maria A. and Woodruff, Trent M. (2020). Complement peptide receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE, 2020 (5). doi: 10.2218/gtopdb/f5/2020.5 |
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2020 Journal Article Is the C3a receptor antagonist SB290157 a useful pharmacological tool?Lee, John D., Taylor, Stephen M. and Woodruff, Trent M. (2020). Is the C3a receptor antagonist SB290157 a useful pharmacological tool?. British Journal of Pharmacology, 177 (24) bph.15264, 5677-5678. doi: 10.1111/bph.15264 |
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2020 Journal Article A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease modelsKumar, Vinod, Lee, John D., Coulson, Elizabeth J. and Woodruff, Trent M. (2020). A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models. Journal of Neurochemistry, 158 (3) jnc.15119, 807-817. doi: 10.1111/jnc.15119 |
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2020 Journal Article COVID-19: Complement, coagulation, and collateral damageLo, Martin W., Kemper, Claudia and Woodruff, Trent M. (2020). COVID-19: Complement, coagulation, and collateral damage. The Journal of Immunology, 205 (6), ji2000644-1495. doi: 10.4049/jimmunol.2000644 |
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2020 Journal Article Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral SclerosisLee, John D., McDonald, Tanya S., Fung, Jenny N. T. and Woodruff, Trent M. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9 |
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2020 Journal Article Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitationHan, Felicity Y., Liu, Yun, Kumar, Vinod, Xu, Weizhi, Yang, Guangze, Zhao, Chun-Xia, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2020). Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation. International Journal of Pharmaceutics, 581 119291, 119291. doi: 10.1016/j.ijpharm.2020.119291 |
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2020 Journal Article Emerging insights into the structure and function of complement C5a receptorsPandey, Shubhi, Maharana, Jagannath, Li, Xaria X., Woodruff, Trent M. and Shukla, Arun K. (2020). Emerging insights into the structure and function of complement C5a receptors. Trends in Biochemical Sciences, 45 (8), 693-705. doi: 10.1016/j.tibs.2020.04.004 |
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2020 Conference Publication T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunityWest, Erin E., Freeley, Simon, Kolev, Martin, Niyonzima, Nathalie, Mogensen, Trine Hyrup, Woodruff, Trent M., Monk, Peter, Lappegard, Knut, Espevik, Terje, Mollnes, Tom Eirik, Christiansen, Mette and Kemper, Claudia (2020). T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.150.23 |
