
Overview
Background
Dr Daniel Liang-Dar Hwang is a genetic epidemiologist and statistical geneticist by training. His research interests include sensory nutrition, causal modelling, and personalized nutrition. Dr Hwang applies statistical models to big data to understand genetic and environmental factors contributing to individual differences in taste and olfactory perception and their relationship with dietary behaviour and chronic conditions (See his research on taste perception in The Conversation). He develops methods for increasing statistical power for gene discovery, estimating intergenerational causal relationships, and personalized intervention. He also works with clinicians to investigate impaired chemosensory perception in cancer patients and COVID-19.
Daniel has a B.Sc from the National Taiwan University, majoring in Biochemical Science and Technology, and an M.Biotech from the University of Pennsylvania. Following graduation, he worked as a research technician in Danielle Reed's lab at the Monell Chemical Senses Center, where he first developed a keen interest in genetics and chemosensory perception. Later, he was awarded scholarships to complete an M.Sc in Nutrition at the University of Washington, under the supervision of Glen Duncan, and a PhD in Genetic Epidemiology at the QIMR Berghofer Medical Research Institute, under the supervision of Nicholas Martin and Margaret Wright. He then joined David Evans's group as a postdoc at the University of Queensland Diamantina Institute (now the Frazer Institute). Dr Hwang is an ARC DECRA Fellow at the Institute for Molecular Bioscience. He is also an Affiliated Scientist at the Monell Chemical Senses Center.
Dr Hwang has published more than 40 peer-reviewed publications. His work has been referred to in international health policy guidelines and a WHO report for the intervention of childhood obesity and in a global patent for personalized wine selection. He is on the editorial boards of BMC Medicine and Twin Research and Human Genetics. Dr Hwang is a Leadership Team member of the Global Consortium for Chemosensory Research, a global initiative to understand the relationship between smell loss and COVID-19 and foster the advancement of chemosensory science. He currently drives an international collaborative project to investigate the impact of COVID-19 vaccinations on long-COVID symptoms. Dr Hwang is a member of the National Committee for Nutrition of the Australian Academy of Science. He contributes to implementing the decadal plan for the science of nutrition in Australia.
Availability
- Dr Daniel Hwang is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Masters (Coursework) of Biotechnology, University of Pennsylvania
- Masters (Research) of Science, University of Washington
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Daniel Hwang’s works on UQ eSpace
2022
Journal Article
Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder
Klein, Louis, D’Urso, Shannon, Eapen, Valsamma, Hwang, Liang-Dar and Lin, Ping-I (2022). Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder. Scientific Reports, 12 (1) 3416. doi: 10.1038/s41598-022-07399-7
2022
Journal Article
Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health
Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2022). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Hypertension, 79 (1), 170-177. doi: 10.1161/hypertensionaha.121.17701
2022
Book Chapter
Integrating family-based and Mendelian randomization designs
Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2022). Integrating family-based and Mendelian randomization designs. Combining human genetics and causal inference to understand human disease and development. (pp. 137-150) edited by George Davey Smith, Rebecca Richmond and Jean-Baptiste Pingault. Cold Spring Harbor, NY, United States: Cold Spring Harbor Laboratory Press.
2021
Conference Publication
Using Adopted Singletons to Partition Maternal Genetic Effects into Pre- and Post-natal Effects on Offspring Phenotype
Hwang, Liang-Dar, Moen, Gunn-Helen and Evans, David M. (2021). Using Adopted Singletons to Partition Maternal Genetic Effects into Pre- and Post-natal Effects on Offspring Phenotype. NEW YORK: SPRINGER.
2021
Conference Publication
Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health
Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Asvold, Bjorn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2021). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Behavior Genetics Association 51st Annual Meeting, Online (Zoom), 29 June 2021. New York, United States: Springer.
2021
Journal Article
Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data
Warrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G. and Evans, David M. (2021). Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data. Nature Communications, 12 (1) 5420, 1-12. doi: 10.1038/s41467-021-25723-z
2021
Other Outputs
Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss
Ohla, Kathrin, Veldhuizen, Maria Geraldine, Green, Tomer, Hannum, Mackenzie E., Bakke, Alyssa J., Moein, Shima T., Tognetti, Arnaud, Postma, Elbrich M., Pellegrino, Robert, Hwang, Liang-Dar, Albayay, Javier, Koyama, Sachiko, Nolden, Alissa, Thomas-Danguin, Thierry, Mucignat-Caretta, Carla, Menger, Nick S., Croijmans, Ilja, Öztürk, Lina, Yanık, Hüseyin, Pierron, Denis, Pereda-Loth, Veronica, Nunez-Parra, Alexia, Pineda, Aldair M. Martinez, Gillespie, David, Farruggia, Michael C., Cecchetto, Cinzia, Fornazieri, Marco A., Philpott, Carl, Voznessenskaya, Vera ... Niv, Masha Y. (2021). Increasing incidence of parosmia and phantosmia in patients recovering from COVID-19 smell loss. doi: 10.1101/2021.08.28.21262763
2021
Conference Publication
Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth and miscarriage
Brito Nunes, Caroline, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Evans, David, Hwang, Liang-Dar and Moen, Gunn-Helen (2021). Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth and miscarriage. Princess Alexandra Hospital (PAH) Health Symposium, Brisbane, QLD Australia, 24 - 27 August 2021.
2021
Other Outputs
Using adopted individuals to partition maternal genetic effects into prenatal and postnatal effects on offspring phenotypes
Hwang, Liang-Dar, Moen, Gunn-Helen and Evans, David M. (2021). Using adopted individuals to partition maternal genetic effects into prenatal and postnatal effects on offspring phenotypes. doi: 10.1101/2021.08.04.455178
2021
Journal Article
Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption
Hwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (4), 441-442. doi: 10.1007/s10519-021-10065-9
2021
Journal Article
Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses
Ong, Jue-Sheng, Derks, Eske M., Eriksson, Mikael, An, Jiyuan, Hwang, Liang-Dar, Easton, Douglas F., Pharoah, Paul P., Berchuck, Andrew, Kelemen, Linda E., Matsuo, Keitaro, Chenevix-Trench, Georgia, Hall, Per, Bojesen, Stig E., Webb, Penelope M. and MacGregor, Stuart (2021). Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses. International Journal of Cancer, 148 (6) ijc.33308, 1338-1350. doi: 10.1002/ijc.33308
2021
Journal Article
The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption
Hwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (3), 223-236. doi: 10.1007/s10519-021-10044-0
2021
Journal Article
Modeling parent-specific genetic nurture in families with missing parental genotypes: application to birthweight and BMI
Tubbs, Justin D., Hwang, Liang-Dar, Luong, Justin, Evans, David M. and Sham, Pak C. (2021). Modeling parent-specific genetic nurture in families with missing parental genotypes: application to birthweight and BMI. Behavior Genetics, 51 (3), 289-300. doi: 10.1007/s10519-020-10040-w
2021
Journal Article
Corrigendum to: More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis
Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G., Niv, Masha Y., Kelly, Christine E., Bakke, Alyssa J., Cooper, Keiland W., Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y., Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B., Gerkin, Richard C., Rohlfs Domínguez, Paloma, Albayay, Javier, Farruggia, Michael C., Bhutani, Surabhi, Fjaeldstad, Alexander W., Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica ... GCCR Group (2021). Corrigendum to: More Than Smell—COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis. Chemical Senses, 46. doi: 10.1093/chemse/bjab050
2021
Journal Article
Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms
Gerkin, Richard C, Ohla, Kathrin, Veldhuizen, Maria G, Joseph, Paule V, Kelly, Christine E, Bakke, Alyssa J, Steele, Kimberley E, Farruggia, Michael C, Pellegrino, Robert, Pepino, Marta Y, Bouysset, Cédric, Soler, Graciela M, Pereda-Loth, Veronica, Dibattista, Michele, Cooper, Keiland W, Croijmans, Ilja, Di Pizio, Antonella, Ozdener, Mehmet Hakan, Fjaeldstad, Alexander W, Lin, Cailu, Sandell, Mari A, Singh, Preet B, Brindha, V Evelyn, Olsson, Shannon B, Saraiva, Luis R, Ahuja, Gaurav, Alwashahi, Mohammed K, Bhutani, Surabhi, D'Errico, Anna ... Navarro, Marta (2021). Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms. Chemical Senses, 46 bjaa081. doi: 10.1093/chemse/bjaa081
2020
Journal Article
A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD)
D'Urso, Shannon, Wang, Geng, Hwang, Liang-Dar, Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2020). A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD). Journal of Developmental Origins of Health and Disease, 12 (5) PII S2040174420001105, 1-6. doi: 10.1017/S2040174420001105
2020
Journal Article
Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs
Hwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel and Evans, David M. (2020). Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs. PLoS Genetics, 16 (10) e1009154, e1009154. doi: 10.1371/journal.pgen.1009154
2020
Journal Article
Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis
Haworth, Simon, Kho, Pik Fang, Holgerson, Pernilla Lif, Hwang, Liang-Dar, Timpson, Nicholas J., Rentería, Miguel E., Johansson, Ingegerd and Cuellar-Partida, Gabriel (2020). Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis. European Journal of Human Genetics, 29 (2), 300-308. doi: 10.1038/s41431-020-00734-4
2020
Journal Article
Genome-wide association study identifies 48 common genetic variants associated with handedness
Cuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y
2020
Journal Article
More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G., Niv, Masha Y., Kelly, Christine E., Bakke, Alyssa J., Cooper, Keiland W., Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y., Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B., Gerkin, Richard C., Rohlfs Domínguez, Paloma, Albayay, Javier, Farruggia, Michael C., Bhutani, Surabhi, Fjaeldstad, Alexander W., Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica ... Hayes, John E. (2020). More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. Chemical Senses, 45 (7), 609-622. doi: 10.1093/chemse/bjaa041
Funding
Current funding
Supervision
Availability
- Dr Daniel Hwang is:
- Available for supervision
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Available projects
-
Develop novel approaches for personalised nutrition using large-scale genetically informative data
Polygenic risk scores have provided informative predictions for highly heritable traits and has been intergrated into risk prediction models along with traditional clinicial measurements to improvde risk prediction of cardiometabolic disease and other inherited health conditions. This project aims to develop novel polygenic scores specifically for priotising interventions or "personalised intervention" rather than risk prediction.
Supervision history
Current supervision
-
Doctor Philosophy
Genetics of sensory nutrition - using genetics to understand how taste and olfactory perception influences eating behaviour and health
Principal Advisor
Other advisors: Dr Brooke Devlin
-
Doctor Philosophy
Multi-omic Approaches to Understanding Septic Shock
Associate Advisor
Other advisors: Professor David Evans
-
Doctor Philosophy
Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans
Associate Advisor
Other advisors: Dr Olivia Wright, Professor Eugeni Roura
-
Doctor Philosophy
Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes
Associate Advisor
Other advisors: Professor David Evans, Dr Gunn-Helen Moen
-
Doctor Philosophy
Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans
Associate Advisor
Other advisors: Dr Olivia Wright, Professor Eugeni Roura
Completed supervision
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2024
Doctor Philosophy
Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes
Associate Advisor
Other advisors: Dr Gunn-Helen Moen, Professor David Evans
-
2023
Doctor Philosophy
Investigating a possible causal relationship between bone mineral density, osteoarthritis, and chronic pain
Associate Advisor
Other advisors: Associate Professor Adam Ewing, Dr John Kemp
Media
Enquiries
Contact Dr Daniel Hwang directly for media enquiries about:
- bitter
- genetics
- smell
- sweet
- taste
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