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Dr Gunn-Helen Moen
Dr

Gunn-Helen Moen

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Overview

Background

Dr Gunn-Helen Moen was awarded her PhD on the "Genetic and environmental etiology of glucose metabolism and cardiometabolic traits during pregnancy and in later life" in 2019 from the Faculty of Medicine at the University of Oslo. After finishing her PhD, she was awarded a Mobility/Marie Sklodowska-Curie Fellowship from the Research Council of Norway and as part of that fellowship she spent two years as a visiting academic at the University of Queensland. She is currently an ARC DECRA fellow at IMB. Her research focus is on using Mendelian randomization to investigate the possible causal effects of maternal environmental exposures during pregnancy on offspring outcomes.

Availability

Dr Gunn-Helen Moen is:
Available for supervision

Works

Search Professor Gunn-Helen Moen’s works on UQ eSpace

45 works between 2016 and 2024

1 - 20 of 45 works

2024

Journal Article

DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits

Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Yengo, Loic, Zeng, Jian, Toivonen, Jarkko, Arvas, Mikko, Beaumont, Robin N., Freathy, Rachel M., Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2024). DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits. Nature Communications, 15 (1) 9255, 9255. doi: 10.1038/s41467-024-53495-9

DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits

2024

Journal Article

Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa)

D'Urso, Shannon, Wootton, Robyn E., Ask, Helga, Brito Nunes, Caroline, Andreassen, Ole A., Hwang, Liang-Dar, Moen, Gunn-Helen, Evans, David M. and Havdahl, Alexandra (2024). Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa). Psychological Medicine, 54 (12), 1-14. doi: 10.1017/S0033291724002216

Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa)

2024

Conference Publication

Common Pitfalls In Mendelian Randomization Studies And How To Avoid Them

Moen, Gunn-Helen and Evans, David M. (2024). Common Pitfalls In Mendelian Randomization Studies And How To Avoid Them. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.030

Common Pitfalls In Mendelian Randomization Studies And How To Avoid Them

2024

Journal Article

Understanding the genetic landscape of gestational diabetes: insights into the causes and consequences of elevated glucose levels in pregnancy

Brito Nunes, Caroline, Borges, Maria Carolina, Freathy, Rachel M., Lawlor, Deborah A., Qvigstad, Elisabeth, Evans, David M. and Moen, Gunn-Helen (2024). Understanding the genetic landscape of gestational diabetes: insights into the causes and consequences of elevated glucose levels in pregnancy. Metabolites, 14 (9) 508, 508. doi: 10.3390/metabo14090508

Understanding the genetic landscape of gestational diabetes: insights into the causes and consequences of elevated glucose levels in pregnancy

2024

Journal Article

Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis

Lee-Ødegård, Sindre, Hjorth, Marit, Olsen, Thomas, Moen, Gunn-Helen, Daubney, Emily, Evans, David M, Hevener, Andrea L, Lusis, Aldons J, Zhou, Mingqi, Seldin, Marcus M, Allayee, Hooman, Hilser, James, Viken, Jonas Krag, Gulseth, Hanne, Norheim, Frode, Drevon, Christian A and Birkeland, Kåre Inge (2024). Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis. eLife, 13 ARTN RP96535. doi: 10.7554/elife.96535

Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis

2024

Journal Article

DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

Linares-Pineda, Teresa M., Fragoso-Bargas, Nicolas, Picón, María José, Molina-Vega, Maria, Jenum, Anne Karen, Sletner, Line, Lee-Ødegård, Sindre, Opsahl, Julia O., Moen, Gunn-Helen, Qvigstad, Elisabeth, Prasad, Rashmi B., Birkeland, Kåre I., Morcillo, Sonsoles and Sommer, Christine (2024). DNA methylation risk score for type 2 diabetes is associated with gestational diabetes. Cardiovascular Diabetology, 23 (1) 68. doi: 10.1186/s12933-024-02151-z

DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

2024

Journal Article

Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain

Opsahl, J. O., Fragoso-Bargas, N., Lee, Y., Carlsen, E. Ø., Lekanova, N., Qvigstad, E., Sletner, L., Jenum, A. K., Lee-Ødegård, S., Prasad, R. B., Birkeland, K. I., Moen, G-H. and Sommer, C. (2024). Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain. International Journal of Obesity, 48 (4), 584-593. doi: 10.1038/s41366-024-01458-x

Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain

2023

Journal Article

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, Robin N., Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Oyvind, Sole-Navais, Pol, Banasik, Karina, Albinana, Clara, Ronkainen, Justiina, Fadista, Joao, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A., Westergaard, David, Srinivasan, Sundararajan, Sanchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J., White, Frederique, Jacques, Pierre-Etienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A. ... Njolstad, Pal R. (2023). Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics, 55 (11), 1807-1819+. doi: 10.1038/s41588-023-01520-w

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

2023

Journal Article

Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa)

D’Urso, Shannon, Moen, Gunn-Helen, Hwang, Liang-Dar, Hannigan, Laurie J., Corfield, Elizabeth C., Ask, Helga, Johannson, Stefan, Njølstad, Pål Rasmus, Beaumont, Robin N., Freathy, Rachel M., Evans, David M. and Havdahl, Alexandra (2023). Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa). JAMA Psychiatry, 81 (2), 144-156. doi: 10.1001/jamapsychiatry.2023.3872

Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa)

2023

Journal Article

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, Robin N., Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Oyvind, Sole-Navais, Pol, Banasik, Karina, Albinana, Clara, Ronkainen, Justiina, Fadista, Joao, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A., Westergaard, David, Srinivasan, Sundararajan, Sanchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J., White, Frederique, Jacques, Pierre-etienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A. ... Njolstad, Pal R. (2023). Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics, 55 (11), 1807-1819. doi: 10.1038/s41588-023-01520-w

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

2023

Journal Article

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, Robin N., Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Oyvind, Sole-Navais, Pol, Banasik, Karina, Albinana, Clara, Ronkainen, Justiina, Fadista, Joao, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A., Westergaard, David, Srinivasan, Sundararajan, Sanchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J., White, Frederique, Jacques, Pierre-etienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A. ... Early Growth Genetics Consortium (2023). Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics, 1786-1787.

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

2023

Journal Article

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, Robin N., Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Øyvind, Solé-Navais, Pol, Banasik, Karina, Albiñana, Clara, Ronkainen, Justiina, Fadista, João, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A., Westergaard, David, Srinivasan, Sundararajan, Sánchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J., White, Frédérique, Jacques, Pierre-Étienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A. ... The Early Growth Genetics (EGG) Consortium (2023). Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics, 55 (11), 1807-1819. doi: 10.1038/s41588-023-01520-w

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

2023

Journal Article

Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight

Solé-Navais, Pol, Flatley, Christopher, Steinthorsdottir, Valgerdur, Vaudel, Marc, Juodakis, Julius, Chen, Jing, Laisk, Triin, LaBella, Abigail L., Westergaard, David, Bacelis, Jonas, Brumpton, Ben, Skotte, Line, Borges, Maria C., Helgeland, Øyvind, Mahajan, Anubha, Wielscher, Matthias, Lin, Frederick, Briggs, Catherine, Wang, Carol A., Moen, Gunn-Helen, Beaumont, Robin N., Bradfield, Jonathan P., Abraham, Abin, Thorleifsson, Gudmar, Gabrielsen, Maiken E., Ostrowski, Sisse R., Modzelewska, Dominika, Nohr, Ellen A., Hypponen, Elina ... Danish Blood Donor Study Genomic Consortium (2023). Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight. Nature Genetics, 55 (7), 1250-1250. doi: 10.1038/s41588-023-01412-z

Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight

2023

Journal Article

Insulin and body mass index decrease serum soluble leptin receptor levels in humans

Sommer, Christine, Vangberg, Kjersti G., Moen, Gunn-Helen, Evans, David M., Lee-Ødegård, Sindre, Blom-Høgestøl, Ingvild K., Sletner, Line, Jenum, Anne K., Drevon, Christian A., Gulseth, Hanne L. and Birkeland, Kåre I. (2023). Insulin and body mass index decrease serum soluble leptin receptor levels in humans. The Journal of Clinical Endocrinology and Metabolism, 108 (5), 1110-1119. doi: 10.1210/clinem/dgac699

Insulin and body mass index decrease serum soluble leptin receptor levels in humans

2023

Journal Article

Genetic effects on the timing of parturition and links to fetal birth weight

Solé-Navais, Pol, Flatley, Christopher, Steinthorsdottir, Valgerdur, Vaudel, Marc, Juodakis, Julius, Chen, Jing, Laisk, Triin, LaBella, Abigail L., Westergaard, David, Bacelis, Jonas, Brumpton, Ben, Skotte, Line, Borges, Maria C., Helgeland, Øyvind, Mahajan, Anubha, Wielscher, Matthias, Lin, Frederick, Briggs, Catherine, Wang, Carol A., Moen, Gunn-Helen, Beaumont, Robin N., Bradfield, Jonathan P., Abraham, Abin, Thorleifsson, Gudmar, Gabrielsen, Maiken E., Ostrowski, Sisse R., Modzelewska, Dominika, Nohr, Ellen A., Hypponen, Elina ... Danish Blood Donor Study Genomic Consortium (2023). Genetic effects on the timing of parturition and links to fetal birth weight. Nature Genetics, 55 (4), 1-9. doi: 10.1038/s41588-023-01343-9

Genetic effects on the timing of parturition and links to fetal birth weight

2023

Conference Publication

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

Nunes, Caroline Brito, Hwang, Liang-Dar, Wang, Geng, Yengo, Loic, Leggatt, Graham, Moen, Gunn-Helen and Evans, David M. (2023). Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane Australia, Mar 21-25, 2023. HEIDELBERG: SPRINGER HEIDELBERG.

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

2023

Other Outputs

GWAS summary statistics of phenotypes generated for the journal article "Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk" published in 2022.

Moen, Gunn-Helen, Evans, David and D’Urso, Shannon (2023). GWAS summary statistics of phenotypes generated for the journal article "Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk" published in 2022.. The University of Queensland. (Dataset) doi: 10.48610/3381ffb

GWAS summary statistics of phenotypes generated for the journal article "Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk" published in 2022.

2023

Journal Article

Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes

Fragoso-Bargas, Nicolas, Page, Christian M., Joubert, Bonnie R., London, Stephanie J., Lee-Ødegård, Sindre, Opsahl, Julia O., Sletner, Line, Jenum, Anne K., Qvigstad, Elisabeth, Prasad, Rashmi B., Moen, Gunn-Helen, Birkeland, Kåre I. and Sommer, Christine (2023). Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes. Epigenomics, 15 (1), 39-52. doi: 10.2217/epi-2022-0427

Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes

2022

Journal Article

Cross-ancestry DNA methylation marks of insulin resistance in pregnancy: an integrative epigenome wide association study

Fragoso-Bargas, Nicolas, Elliott, Hannah R., Lee-Ødegård, Sindre, Opsahl, Julia O., Sletner, Line, Jenum, Anne Karen, Drevon, Christian A., Qvigstad, Elisabeth, Moen, Gunn-Helen, Birkeland, Kåre I., Prasad, Rashmi B. and Sommer, Christine (2022). Cross-ancestry DNA methylation marks of insulin resistance in pregnancy: an integrative epigenome wide association study. Diabetes, 72 (3), 415-426. doi: 10.2337/db22-0504

Cross-ancestry DNA methylation marks of insulin resistance in pregnancy: an integrative epigenome wide association study

2022

Journal Article

Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT study

Moen, Gunn-Helen, Nivard, Michel, Bhatta, Laxmi, Warrington, Nicole M., Willer, Cristen, Åsvold, Bjørn Olav, Brumpton, Ben and Evans, David M. (2022). Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT study. Behavior Genetics, 53 (1), 1-13. doi: 10.1007/s10519-022-10116-9

Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT study

Funding

Current funding

  • 2022 - 2026
    Testing Effects of Environmental Exposures on Subsequent Human Generations
    ARC Discovery Early Career Researcher Award
    Open grant

Supervision

Availability

Dr Gunn-Helen Moen is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Testing effect of environmental exposures on subsequent human generations

    Depending on the applicant’s level of experience, they will help develop and/or apply statistical genetics approaches to investigate the possible existence of transgenerational effects on human phenotypes, using cohorts such as the Norwegian HUNT cohort (which has a large number of parent-offspring pairs) and UK Biobank. A PhD is about learning new skills and learning how to do research. Our ideal candidate will have knowledge or keen interest in learning genetics, epidemiology, statistics, unix and shell scripting, and statistical software such as R. You will work closely with an experienced researcher on the project. There will also be possibility for a research stay in Norway during this PhD. The advertised projects are fundamentally quantitative and computer-based, and so evidence of aptitude in these areas is essential. The candidate should also have the ability to design, plan, and execute experiments and be proficient in English, both written and oral.

Supervision history

Current supervision

  • Doctor Philosophy

    Understanding the genetic epidemiology of women's reproductive health

    Associate Advisor

    Other advisors: Professor David Evans

  • Doctor Philosophy

    Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes

    Associate Advisor

    Other advisors: Dr Daniel Hwang, Professor David Evans

Completed supervision

Media

Enquiries

For media enquiries about Dr Gunn-Helen Moen's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au