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Dr Daniel Hwang
Dr

Daniel Hwang

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+61 7 344 37976

Overview

Background

Dr Daniel Liang-Dar Hwang is a genetic epidemiologist and statistical geneticist by training. His research interests include sensory nutrition, causal modelling, and personalized nutrition. Dr Hwang applies statistical models to big data to understand genetic and environmental factors contributing to individual differences in taste and olfactory perception and their relationship with dietary behaviour and chronic conditions (See his research on taste perception in The Conversation). He develops methods for increasing statistical power for gene discovery, estimating intergenerational causal relationships, and personalized intervention. He also works with clinicians to investigate impaired chemosensory perception in cancer patients and COVID-19.

Daniel has a B.Sc from the National Taiwan University, majoring in Biochemical Science and Technology, and an M.Biotech from the University of Pennsylvania. Following graduation, he worked as a research technician in Danielle Reed's lab at the Monell Chemical Senses Center, where he first developed a keen interest in genetics and chemosensory perception. Later, he was awarded scholarships to complete an M.Sc in Nutrition at the University of Washington, under the supervision of Glen Duncan, and a PhD in Genetic Epidemiology at the QIMR Berghofer Medical Research Institute, under the supervision of Nicholas Martin and Margaret Wright. He then joined David Evans's group as a postdoc at the University of Queensland Diamantina Institute (now the Frazer Institute). Dr Hwang is an ARC DECRA Fellow at the Institute for Molecular Bioscience.

Dr Hwang has published more than 40 peer-reviewed publications. His work has been referred to in international health policy guidelines and a WHO report for the intervention of childhood obesity and in a global patent for personalized wine selection. He is on the editorial boards of BMC Medicine and Twin Research and Human Genetics. Dr Hwang is a Leadership Team member of the Global Consortium for Chemosensory Research, a global initiative to understand the relationship between smell loss and COVID-19 and foster the advancement of chemosensory science. He currently drives an international collaborative project to investigate the impact of COVID-19 vaccinations on long-COVID symptoms. Dr Hwang is a member of the National Committee for Nutrition of the Australian Academy of Science. He contributes to implementing the decadal plan for the science of nutrition in Australia.

Availability

Dr Daniel Hwang is:
Available for supervision
Media expert

Qualifications

  • Masters (Coursework) of Biotechnology, University of Pennsylvania
  • Masters (Research) of Science, University of Washington
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Daniel Hwang’s works on UQ eSpace

63 works between 2012 and 2024

1 - 20 of 63 works

2024

Journal Article

A note on modelling bidirectional feedback loops in Mendelian randomization studies

Hwang, Liang-Dar and Evans, David M. (2024). A note on modelling bidirectional feedback loops in Mendelian randomization studies. Behavior Genetics, 54 (4), 367-373. doi: 10.1007/s10519-024-10183-0

A note on modelling bidirectional feedback loops in Mendelian randomization studies

2024

Journal Article

Advancing the decadal plan for the science of nutrition: progressing a framework for implementation

Truby, Helen, Allman‐Farinelli, Margaret, Beck, Eleanor J., Beckett, Emma L., Bondonno, Catherine, Dordevic, Aimee L., Livingstone, Katherine M., Willcox, Jane, Wilkinson, Shelley A., the National Committee for Nutrition and its working groups, Hwang, Liang-Dar, McNaughton, Sarah, Padayachee, Anneline, Roura, Eugeni, Gidley, Mike and Canfell, Oliver (2024). Advancing the decadal plan for the science of nutrition: progressing a framework for implementation. Nutrition and Dietetics, 81 (2), 133-148. doi: 10.1111/1747-0080.12876

Advancing the decadal plan for the science of nutrition: progressing a framework for implementation

2024

Conference Publication

Several genetic SNPs identified in acute appendicitis patients including the HLA-C known to be related to coeliac disease in a Genome-Wide Association Study

Ryoo, M., Hwang, L-D., Wright, O., Brown, J., de Pouplana, L.R. and Roura, E. (2024). Several genetic SNPs identified in acute appendicitis patients including the HLA-C known to be related to coeliac disease in a Genome-Wide Association Study. 57th Nutrition Society of New Zealand and 47th Nutrition Society of Australia Joint Annual Scientific Meeting, Auckland, New Zealand, 28 November – 1 December 2023. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/s0029665124001721

Several genetic SNPs identified in acute appendicitis patients including the HLA-C known to be related to coeliac disease in a Genome-Wide Association Study

2024

Journal Article

Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.–A study protocol

Cheung, May M., Hubert, Patrice A., Reed, Danielle R., Pouget, Enrique R., Jiang, Xinyin and Hwang, Liang-Dar (2024). Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.–A study protocol. PLoS One, 19 (4 April) e0300071, e0300071. doi: 10.1371/journal.pone.0300071

Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.–A study protocol

2023

Journal Article

New insights into polygenic score–Lifestyle interactions for cardiometabolic risk factors from genome-wide interaction analyses

D’Urso, Shannon and Hwang, Liang-Dar (2023). New insights into polygenic score–Lifestyle interactions for cardiometabolic risk factors from genome-wide interaction analyses. Nutrients, 15 (22) 4815, 1-14. doi: 10.3390/nu15224815

New insights into polygenic score–Lifestyle interactions for cardiometabolic risk factors from genome-wide interaction analyses

2023

Journal Article

Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa)

D’Urso, Shannon, Moen, Gunn-Helen, Hwang, Liang-Dar, Hannigan, Laurie J., Corfield, Elizabeth C., Ask, Helga, Johannson, Stefan, Njølstad, Pål Rasmus, Beaumont, Robin N., Freathy, Rachel M., Evans, David M. and Havdahl, Alexandra (2023). Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa). JAMA Psychiatry, 81 (2), 144-156. doi: 10.1001/jamapsychiatry.2023.3872

Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa)

2023

Conference Publication

Consumption of diets rich in animal protein, saturated fat, or sodium, and low in fibre are associated with increased risk of acute appendicitis

Ryoo, M., Hwang, D., Wright, O., Brown, J. and Roura, E. (2023). Consumption of diets rich in animal protein, saturated fat, or sodium, and low in fibre are associated with increased risk of acute appendicitis. 46th Annual Scientific Meeting of the Nutrition Society of Australia, Perth, WA Australia, 29 November – 2 December 2022. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/s0029665123001258

Consumption of diets rich in animal protein, saturated fat, or sodium, and low in fibre are associated with increased risk of acute appendicitis

2023

Conference Publication

Increased risk of acute appendicitis linked to biological sex, ethnic background, obesity, and smoking status

Ryoo, M., Hwang, D., Wright, O., Brown, J. and Roura, E. (2023). Increased risk of acute appendicitis linked to biological sex, ethnic background, obesity, and smoking status. 46th Annual Scientific Meeting of the Nutrition Society of Australia, Perth, WA Australia, 29 November – 2 December 2022. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/s0029665123001714

Increased risk of acute appendicitis linked to biological sex, ethnic background, obesity, and smoking status

2023

Conference Publication

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

Nunes, Caroline Brito, Hwang, Liang-Dar, Wang, Geng, Yengo, Loic, Leggatt, Graham, Moen, Gunn-Helen and Evans, David M. (2023). Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane Australia, Mar 21-25, 2023. HEIDELBERG: SPRINGER HEIDELBERG.

Contributions of Maternal Classical HLA Alleles and Spousal HLA Incompatibility to the Risk of Miscarriages and Stillbirths

2022

Journal Article

Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk

D’Urso, Shannon, Arumugam, Pooja, Weider, Therese, Hwang, Liang-Dar, Bond, Tom A., Kemp, John P., Warrington, Nicole M., Evans, David M., O’Mara, Tracy A. and Moen, Gunn-Helen (2022). Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk. BMC Medicine, 20 (1) 419, 1-17. doi: 10.1186/s12916-022-02585-w

Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk

2022

Journal Article

Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes

Hwang, Liang-Dar, Moen, Gunn-Helen and Evans, David M. (2022). Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes. eLife, 11 e73671, 1-27. doi: 10.7554/elife.73671

Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes

2022

Journal Article

Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth

Brito Nunes, Caroline, Huang, Peiyuan, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Wootton, Robyn E., Borges, Maria Carolina, Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Hwang, Liang-Dar and Moen, Gunn-Helen (2022). Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. International Journal of Epidemiology, 52 (1), 1-13. doi: 10.1093/ije/dyac121

Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth

2022

Journal Article

A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss

Ohla, K, Veldhuizen, M G, Green, T, Hannum, M E, Bakke, A J, Moein, S T, Tognetti, A, Postma, E M, Pellegrino, R, Hwang, D L D, Albayay, J, Koyama, S, Nolden, A A, Thomas-Danguin, T, Mucignat-Caretta, C, Menger, N S, Croijmans, I, Öztürk, L, Yanık, H, Pierron, D, Pereda-Loth, V, Nunez-Parra, A, Martinez Pineda, A M, Gillespie, D, Farruggia, M C, Cecchetto, C, Fornazieri, M A, Philpott, C, Voznessenskaya, V ... Niv, M Y (2022). A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss. Rhinology, 60 (3), 207-217. doi: 10.4193/Rhin21.415

A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss

2022

Journal Article

Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder

Klein, Louis, D’Urso, Shannon, Eapen, Valsamma, Hwang, Liang-Dar and Lin, Ping-I (2022). Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder. Scientific Reports, 12 (1) 3416. doi: 10.1038/s41598-022-07399-7

Exploring polygenic contributors to subgroups of comorbid conditions in autism spectrum disorder

2022

Journal Article

Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health

Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2022). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Hypertension, 79 (1), 170-177. doi: 10.1161/hypertensionaha.121.17701

Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health

2022

Book Chapter

Integrating family-based and Mendelian randomization designs

Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2022). Integrating family-based and Mendelian randomization designs. Combining human genetics and causal inference to understand human disease and development. (pp. 137-150) edited by George Davey Smith, Rebecca Richmond and Jean-Baptiste Pingault. Cold Spring Harbor, NY, United States: Cold Spring Harbor Laboratory Press.

Integrating family-based and Mendelian randomization designs

2021

Conference Publication

Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health

Wang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Asvold, Bjorn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2021). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Behavior Genetics Association 51st Annual Meeting, Online (Zoom), 29 June 2021. New York, United States: Springer.

Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health

2021

Conference Publication

Using Adopted Singletons to Partition Maternal Genetic Effects into Pre- and Post-natal Effects on Offspring Phenotype

Hwang, Liang-Dar, Moen, Gunn-Helen and Evans, David M. (2021). Using Adopted Singletons to Partition Maternal Genetic Effects into Pre- and Post-natal Effects on Offspring Phenotype. NEW YORK: SPRINGER.

Using Adopted Singletons to Partition Maternal Genetic Effects into Pre- and Post-natal Effects on Offspring Phenotype

2021

Journal Article

Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data

Warrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G. and Evans, David M. (2021). Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data. Nature Communications, 12 (1) 5420, 1-12. doi: 10.1038/s41467-021-25723-z

Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data

2021

Journal Article

Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

Hwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (4), 441-442. doi: 10.1007/s10519-021-10065-9

Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

Funding

Current funding

  • 2024 - 2027
    Causal relationship between taste and smell perception and eating behaviour
    ARC Discovery Early Career Researcher Award
    Open grant

Supervision

Availability

Dr Daniel Hwang is:
Available for supervision

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Available projects

  • Develop novel approaches for personalised nutrition using large-scale genetically informative data

    Polygenic risk scores have provided informative predictions for highly heritable traits and has been intergrated into risk prediction models along with traditional clinicial measurements to improvde risk prediction of cardiometabolic disease and other inherited health conditions. This project aims to develop novel polygenic scores specifically for priotising interventions or "personalised intervention" rather than risk prediction.

Supervision history

Current supervision

  • Doctor Philosophy

    Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes

    Associate Advisor

    Other advisors: Professor David Evans, Dr Gunn-Helen Moen

  • Doctor Philosophy

    Multi-omic Approaches to Understanding Septic Shock

    Associate Advisor

    Other advisors: Professor David Evans

  • Doctor Philosophy

    Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans

    Associate Advisor

    Other advisors: Dr Olivia Wright, Professor Eugeni Roura

Completed supervision

Media

Enquiries

Contact Dr Daniel Hwang directly for media enquiries about:

  • bitter
  • genetics
  • smell
  • sweet
  • taste

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au