
Overview
Background
Dr Daniel Liang-Dar Hwang is a genetic epidemiologist and statistical geneticist by training. His research interests include sensory nutrition, causal modelling, and personalized nutrition. Dr Hwang applies statistical models to big data to understand genetic and environmental factors contributing to individual differences in taste and olfactory perception and their relationship with dietary behaviour and chronic conditions (See his research on taste perception in The Conversation). He develops methods for increasing statistical power for gene discovery, estimating intergenerational causal relationships, and personalized intervention. He also works with clinicians to investigate impaired chemosensory perception in cancer patients and COVID-19.
Daniel has a B.Sc from the National Taiwan University, majoring in Biochemical Science and Technology, and an M.Biotech from the University of Pennsylvania. Following graduation, he worked as a research technician in Danielle Reed's lab at the Monell Chemical Senses Center, where he first developed a keen interest in genetics and chemosensory perception. Later, he was awarded scholarships to complete an M.Sc in Nutrition at the University of Washington, under the supervision of Glen Duncan, and a PhD in Genetic Epidemiology at the QIMR Berghofer Medical Research Institute, under the supervision of Nicholas Martin and Margaret Wright. He then joined David Evans's group as a postdoc at the University of Queensland Diamantina Institute (now the Frazer Institute). Dr Hwang is an ARC DECRA Fellow at the Institute for Molecular Bioscience. He is also an Affiliated Scientist at the Monell Chemical Senses Center.
Dr Hwang has published more than 50 peer-reviewed publications. His work has been referred to in international health policy guidelines and a WHO report for the intervention of childhood obesity and in a global patent for personalized wine selection. He is on the editorial boards of BMC Medicine and Twin Research and Human Genetics. Dr Hwang is a Leadership Team member of the Global Consortium for Chemosensory Research, a global initiative to understand the relationship between smell loss and COVID-19 and foster the advancement of chemosensory science. He currently drives an international collaborative project to investigate the impact of COVID-19 vaccinations on long-COVID symptoms. Dr Hwang is a member of the National Committee for Nutrition of the Australian Academy of Science. He contributes to implementing the decadal plan for the science of nutrition in Australia.
Availability
- Dr Daniel Hwang is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Masters (Coursework) of Biotechnology, University of Pennsylvania
- Masters (Research) of Science, University of Washington
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Daniel Hwang’s works on UQ eSpace
2025
Journal Article
Genetic and physiological influences on sweet taste preference among young adults in Malaysia: associations with TAS1R2/TAS1R3 variants, body composition, and food liking and intake frequency
Say, Yee-How, Siew, Kah Tao, Letchumanan, Geetha, Olarewaju, Victoria Olubunmi, Tham, Hazel Zi Qi, Ong, Jue-Sheng and Hwang, Liang-Dar (2025). Genetic and physiological influences on sweet taste preference among young adults in Malaysia: associations with TAS1R2/TAS1R3 variants, body composition, and food liking and intake frequency. Food Quality and Preference, 133 105626, 1-12. doi: 10.1016/j.foodqual.2025.105626
2025
Journal Article
Combining Transancestry Polygenic Risk Scores and Family History for Predicting Psychiatric Disorders: Insights From the Taiwan Biobank
Hwang, Liang-Dar (2025). Combining Transancestry Polygenic Risk Scores and Family History for Predicting Psychiatric Disorders: Insights From the Taiwan Biobank. Biological Psychiatry, 98 (6), 440-441. doi: 10.1016/j.biopsych.2025.06.020
2025
Journal Article
Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking
He, Weixiong, van der Most, Peter J., Ong, Jue-Sheng, Hwang, Liang-Dar, Wu, Yeda, Magnø, Morten S., Vehof, Jelle, Krebs, Kristi, Mauring, Laura, Õunap, Katrin, Abner, Erik, Martin, Nicholas G., Plotnikov, Denis, Jiang, Chen, Melles, Ronald B., Gharahkhani, Puya, Snieder, Harold, Palumaa, Teele, Kaljurand, Kuldar, Guggenheim, Jeremy A., Mackey, David A., Engle, Elizabeth C., Choquet, Hélène, MacGregor, Stuart, Lifelines Cohort Study, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A. ... Wray, Naomi (2025). Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking. Nature Communications, 16 (1) 7890, 1-14. doi: 10.1038/s41467-025-62456-9
2025
Journal Article
The genetics of low and high birthweight and their relationship with cardiometabolic disease
Moen, Gunn-Helen, Hwang, Liang-Dar, Brito Nunes, Caroline, Warrington, Nicole M. and Evans, David M. (2025). The genetics of low and high birthweight and their relationship with cardiometabolic disease. Diabetologia, 68 (7), 1452-1462. doi: 10.1007/s00125-025-06420-8
2025
Journal Article
Genome-wide association study of the taste and hedonic ratings of the low-calorie sweetener acesulfame potassium
Kan, Mengyuan, Saraiva, Luis R., Hwang, Liang-Dar, Lowenthal, Elizabeth D., Himes, Blanca E. and Mennella, Julie A. (2025). Genome-wide association study of the taste and hedonic ratings of the low-calorie sweetener acesulfame potassium. Scientific Reports, 15 (1) 22121, 1-13. doi: 10.1038/s41598-025-05739-x
2025
Journal Article
Phenome-wide investigation of dietary and health outcomes associated with bitter taste receptor gene TAS2R38
Brito Nunes, Caroline, Lim, Amanda Wei-Yin, Dy, Quimbe, Ong, Jue-Sheng and Hwang, Liang-Dar (2025). Phenome-wide investigation of dietary and health outcomes associated with bitter taste receptor gene TAS2R38. European Journal of Nutrition, 64 (5) 218, 218-5. doi: 10.1007/s00394-025-03718-6
2025
Conference Publication
Using nonsynonymous mutations in taste and olfactory receptor genes to investigate the influence of eating behaviour on health
Hwang, L. -d., Lin, C., Reed, D. R. and Joseph, P. V. (2025). Using nonsynonymous mutations in taste and olfactory receptor genes to investigate the influence of eating behaviour on health. CAMBRIDGE: CAMBRIDGE UNIV PRESS. doi: 10.1017/S0029665125000953
2025
Journal Article
Gut microbiome and body composition with sorbitol intake during early lifespan
Chu, Ying-Yueh, Yang, Yu-Chen S. H., Hsu, Shih-Yuan, Fan, Hsien-Yu, Hwang, Liang-Dar, Nacis, Jacus S. and Chen, Yang Ching (2025). Gut microbiome and body composition with sorbitol intake during early lifespan. Nutrition, 130 112614, 1-9. doi: 10.1016/j.nut.2024.112614
2024
Conference Publication
INFLUENCE OF COMMON MISSENSE VARIANTS IN CHEMOSENSORY RECEPTOR GENES ON FOOD PREFERENCES
Reed, Danielle, Hwang, Liang-Dar, Lin, Cailu and Joseph, Paule (2024). INFLUENCE OF COMMON MISSENSE VARIANTS IN CHEMOSENSORY RECEPTOR GENES ON FOOD PREFERENCES. 46th Annual Meeting of the Association-for-Chemoreception-Sciences (AChemS), Bonita Springs Fl, Apr 17-20, 2024. OXFORD: OXFORD UNIV PRESS.
2024
Journal Article
Understanding the genetic architecture of vitamin status biomarkers in the genome-wide association study era: biological insights and clinical significance
Reay, William R., Clarke, Erin D., Albiñana, Clara and Hwang, Liang-Dar (2024). Understanding the genetic architecture of vitamin status biomarkers in the genome-wide association study era: biological insights and clinical significance. Advances in Nutrition, 15 (12) 100344, 100344. doi: 10.1016/j.advnut.2024.100344
2024
Journal Article
DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits
Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Yengo, Loic, Zeng, Jian, Toivonen, Jarkko, Arvas, Mikko, Beaumont, Robin N., Freathy, Rachel M., Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2024). DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits. Nature Communications, 15 (1) 9255, 1-14. doi: 10.1038/s41467-024-53495-9
2024
Journal Article
Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa)
D'Urso, Shannon, Wootton, Robyn E., Ask, Helga, Brito Nunes, Caroline, Andreassen, Ole A., Hwang, Liang-Dar, Moen, Gunn-Helen, Evans, David M. and Havdahl, Alexandra (2024). Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa). Psychological Medicine, 54 (12), 1-14. doi: 10.1017/S0033291724002216
2024
Journal Article
A note on modelling bidirectional feedback loops in Mendelian randomization studies
Hwang, Liang-Dar and Evans, David M. (2024). A note on modelling bidirectional feedback loops in Mendelian randomization studies. Behavior Genetics, 54 (4), 367-373. doi: 10.1007/s10519-024-10183-0
2024
Journal Article
Advancing the decadal plan for the science of nutrition: progressing a framework for implementation
Truby, Helen, Allman‐Farinelli, Margaret, Beck, Eleanor J., Beckett, Emma L., Bondonno, Catherine, Dordevic, Aimee L., Livingstone, Katherine M., Willcox, Jane, Wilkinson, Shelley A., the National Committee for Nutrition and its working groups, Hwang, Liang-Dar, McNaughton, Sarah, Padayachee, Anneline, Roura, Eugeni, Gidley, Mike and Canfell, Oliver (2024). Advancing the decadal plan for the science of nutrition: progressing a framework for implementation. Nutrition and Dietetics, 81 (2), 133-148. doi: 10.1111/1747-0080.12876
2024
Conference Publication
Several genetic SNPs identified in acute appendicitis patients including the HLA-C known to be related to coeliac disease in a Genome-Wide Association Study
Ryoo, M., Hwang, L-D., Wright, O., Brown, J., de Pouplana, L.R. and Roura, E. (2024). Several genetic SNPs identified in acute appendicitis patients including the HLA-C known to be related to coeliac disease in a Genome-Wide Association Study. 57th Nutrition Society of New Zealand and 47th Nutrition Society of Australia Joint Annual Scientific Meeting, Auckland, New Zealand, 28 November – 1 December 2023. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/s0029665124001721
2024
Journal Article
Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.–A study protocol
Cheung, May M., Hubert, Patrice A., Reed, Danielle R., Pouget, Enrique R., Jiang, Xinyin and Hwang, Liang-Dar (2024). Understanding the determinants of sweet taste liking in the African and East Asian ancestry groups in the U.S.–A study protocol. PLoS One, 19 (4 April) e0300071, e0300071. doi: 10.1371/journal.pone.0300071
2024
Other Outputs
Hwang_2024_NatCommun
Hwang, Daniel and Evans, David (2024). Hwang_2024_NatCommun. The University of Queensland. (Dataset) doi: 10.48610/9f69854
2023
Journal Article
New insights into polygenic score–Lifestyle interactions for cardiometabolic risk factors from genome-wide interaction analyses
D’Urso, Shannon and Hwang, Liang-Dar (2023). New insights into polygenic score–Lifestyle interactions for cardiometabolic risk factors from genome-wide interaction analyses. Nutrients, 15 (22) 4815, 1-14. doi: 10.3390/nu15224815
2023
Journal Article
Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa)
D’Urso, Shannon, Moen, Gunn-Helen, Hwang, Liang-Dar, Hannigan, Laurie J., Corfield, Elizabeth C., Ask, Helga, Johannson, Stefan, Njølstad, Pål Rasmus, Beaumont, Robin N., Freathy, Rachel M., Evans, David M. and Havdahl, Alexandra (2023). Intrauterine growth and offspring neurodevelopmental traits: a Mendelian randomization analysis of the Norwegian mother, father and child cohort study (MoBa). JAMA Psychiatry, 81 (2), 144-156. doi: 10.1001/jamapsychiatry.2023.3872
2023
Conference Publication
Phenome-wide association analysis of supertaster gene TAS2R38 reveals novel relationship with bipolar disorder and kidney function
Brito Nunes, Caroline, Lim, Amanda W.Y., Dy, Quimbe, Ong, Jue-Sheng and Hwang, Liang-Dar (2023). Phenome-wide association analysis of supertaster gene TAS2R38 reveals novel relationship with bipolar disorder and kidney function. Boden Research Conference: Advancing the Science of Precision and Personalised Nutrition, Canberra, ACT, Australia, 19-20 October 2023. OXFORD: OXFORD UNIV PRESS.
Funding
Current funding
Supervision
Availability
- Dr Daniel Hwang is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Genetics of sensory nutrition - using genetics to understand how taste and olfactory perception influences eating behaviour and health
Principal Advisor
Other advisors: Dr Brooke Devlin
-
Doctor Philosophy
Improved understanding of complex traits through intermediate phenotypes and robust methodologies
Associate Advisor
Other advisors: Professor David Evans
-
Doctor Philosophy
Investigating the relationship between adverse perinatal environments and the development of childhood depression and anxiety using statistical genetics methods
Associate Advisor
Other advisors: Professor David Evans
-
Doctor Philosophy
Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans
Associate Advisor
Other advisors: Dr Olivia Wright, Professor Eugeni Roura
Completed supervision
-
2024
Doctor Philosophy
Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes
Associate Advisor
Other advisors: Dr Gunn-Helen Moen, Professor David Evans
-
2023
Doctor Philosophy
Investigating a possible causal relationship between bone mineral density, osteoarthritis, and chronic pain
Associate Advisor
Other advisors: Associate Professor Adam Ewing, Dr John Kemp
Media
Enquiries
Contact Dr Daniel Hwang directly for media enquiries about:
- bitter
- genetics
- smell
- sweet
- taste
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