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Dr Daniel Hwang
Dr

Daniel Hwang

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Phone: 
+61 7 334 62630

Overview

Background

Dr Daniel Liang-Dar Hwang is a genetic epidemiologist and statistical geneticist by training. His research interests include sensory nutrition, causal modelling, and personalized nutrition. Dr Hwang applies statistical models to big data to understand genetic and environmental factors contributing to individual differences in taste and olfactory perception and their relationship with dietary behaviour and chronic conditions (See his research on taste perception in The Conversation). He develops methods for increasing statistical power for gene discovery, estimating intergenerational causal relationships, and personalized intervention. He also works with clinicians to investigate impaired chemosensory perception in cancer patients and COVID-19.

Daniel has a B.Sc from the National Taiwan University, majoring in Biochemical Science and Technology, and an M.Biotech from the University of Pennsylvania. Following graduation, he worked as a research technician in Danielle Reed's lab at the Monell Chemical Senses Center, where he first developed a keen interest in genetics and chemosensory perception. Later, he was awarded scholarships to complete an M.Sc in Nutrition at the University of Washington, under the supervision of Glen Duncan, and a PhD in Genetic Epidemiology at the QIMR Berghofer Medical Research Institute, under the supervision of Nicholas Martin and Margaret Wright. He then joined David Evans's group as a postdoc at the University of Queensland Diamantina Institute (now the Frazer Institute). Dr Hwang is an ARC DECRA Fellow at the Institute for Molecular Bioscience. He is also an Affiliated Scientist at the Monell Chemical Senses Center.

Dr Hwang has published more than 40 peer-reviewed publications. His work has been referred to in international health policy guidelines and a WHO report for the intervention of childhood obesity and in a global patent for personalized wine selection. He is on the editorial boards of BMC Medicine and Twin Research and Human Genetics. Dr Hwang is a Leadership Team member of the Global Consortium for Chemosensory Research, a global initiative to understand the relationship between smell loss and COVID-19 and foster the advancement of chemosensory science. He currently drives an international collaborative project to investigate the impact of COVID-19 vaccinations on long-COVID symptoms. Dr Hwang is a member of the National Committee for Nutrition of the Australian Academy of Science. He contributes to implementing the decadal plan for the science of nutrition in Australia.

Availability

Dr Daniel Hwang is:
Available for supervision
Media expert

Qualifications

  • Masters (Coursework) of Biotechnology, University of Pennsylvania
  • Masters (Research) of Science, University of Washington
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Daniel Hwang’s works on UQ eSpace

71 works between 2012 and 2024

41 - 60 of 71 works

2020

Journal Article

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G. and Corneli, Marilyn C. (2020). Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization. Scientific Reports, 10 (1) 4778, 4778. doi: 10.1038/s41598-020-60488-3

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

2020

Journal Article

Integrating family-based and Mendelian randomization designs

Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2020). Integrating family-based and Mendelian randomization designs. Cold Spring Harbor Perspectives in Medicine, 11 (3) a039503, 1-15. doi: 10.1101/cshperspect.a039503

Integrating family-based and Mendelian randomization designs

2020

Journal Article

Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'

Hwang, Liang-Dar (2020). Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'. Twin Research and Human Genetics, 23 (2), 1-2. doi: 10.1017/thg.2020.19

Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'

2019

Journal Article

Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review

Nolden, Alissa A., Hwang, Liang-Dar, Boltong, Anna and Reed, Danielle R. (2019). Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review. Nutrients, 11 (10) 2285, 2285. doi: 10.3390/nu11102285

Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review

2019

Journal Article

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

Hwang, Liang-Dar, Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2019). Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight. International Journal of Epidemiology, 48 (5), 1457-1467. doi: 10.1093/ije/dyz160

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

2019

Journal Article

New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

Hwang, Liang-Dar, Lin, Cailu, Gharahkhani, Puya, Cuellar-Partida, Gabriel, Ong, Jue-Sheng, An, Jiyuan, Gordon, Scott D., Zhu, Gu, MacGregor, Stuart, Lawlor, Deborah A., Breslin, Paul A. S., Wright, Margaret J., Martin, Nicholas G. and Reed, Danielle R. (2019). New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances. The American Journal of Clinical Nutrition, 109 (6), 1724-1737. doi: 10.1093/ajcn/nqz043

New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

2019

Journal Article

Associations between brain structure and perceived intensity of sweet and bitter tastes

Hwang, Liang-Dar, Strike, Lachlan T, Couvy-Duchesne, Baptiste, de Zubicaray, Greig I, McMahon, Katie, Breslin, Paul A. S., Reed, Danielle R., Martin, Nicholas G. and Wright, Margaret J. (2019). Associations between brain structure and perceived intensity of sweet and bitter tastes. Behavioural Brain Research, 363, 103-108. doi: 10.1016/j.bbr.2019.01.046

Associations between brain structure and perceived intensity of sweet and bitter tastes

2019

Journal Article

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

Evans, David M., Moen, Gunn-Helen, Hwang, Liang-Dar, Lawlor, Debbie A. and Warrington, Nicole M. (2019). Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization. International Journal of Epidemiology, 48 (3), 861-875. doi: 10.1093/ije/dyz019

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

2019

Conference Publication

Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses

Cuéllar-Partida, Gabriel, Lundberg, Mischa, Campos-González, Adrian I., Kho, Pik Fang, D’Urso, Shannon, Hwang, Liang-Dar, Ngo, Trung Thanh and Rentería, Miguel E. (2019). Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses. American Society of Human Genetics (ASHG) 69th Annual Meeting, Houston, TX United States, 15–19 October 2019.

Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses

2019

Conference Publication

Genetic epidemiology of back pain: Examining causality with Complex Traits Virtual Lab

Ngo, Trung Thanh, Lundberg, Mischa, Campos-González, Adrian, Kho, Pik Fang, D’Urso, Shannon, Hwang, Liang-Dar, Rentería, Miguel and Cuéllar-Partida, Gabriel (2019). Genetic epidemiology of back pain: Examining causality with Complex Traits Virtual Lab. Australasian Epidemiological Association 2019 Annual Scientific Meeting — 'Epidemiology in the real world', South Brisbane, QLD Australia, 23–25 October 2019.

Genetic epidemiology of back pain: Examining causality with Complex Traits Virtual Lab

2019

Conference Publication

Using Mendelian randomization to estimate the causal effect of maternal (intrauterine) exposures on late onset offspring outcomes

Evans, David, Warrington, Nicole, Partida, Gabriel Cuellar and Hwang, Daniel (2019). Using Mendelian randomization to estimate the causal effect of maternal (intrauterine) exposures on late onset offspring outcomes. 49th Annual Meeting of the Behavior Genetics Association (BGA), Stockholm, Sweden, 26-29 June, 2019. New York, NY, United States: Springer New York LLC. doi: 10.1007/s10519-019-09973-8

Using Mendelian randomization to estimate the causal effect of maternal (intrauterine) exposures on late onset offspring outcomes

2018

Journal Article

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G. and Cornelis, Marilyn C. (2018). Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization. Scientific Reports, 8 (1) 16414, 16414. doi: 10.1038/s41598-018-34713-z

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

2018

Journal Article

Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste

Hwang, Liang-Dar, Gharahkhani, Puya, Breslin, Paul A. S., Gordon, Scott D., Zhu, Gu, Martin, Nicholas G., Reed, Danielle R. and Wright, Margaret J. (2018). Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste. BMC Genomics, 19 (678) 678, 678. doi: 10.1186/s12864-018-5058-2

Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste

2018

Other Outputs

Individual differences in taste and their association with genes, dietary behaviour, and brain structure

Hwang, Liang-Dar (Daniel) (2018). Individual differences in taste and their association with genes, dietary behaviour, and brain structure. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2018.573

Individual differences in taste and their association with genes, dietary behaviour, and brain structure

2018

Conference Publication

F271. The Moderating Roles of Parental Monitoring and Peer Group Deviance on Polygenic Risk for Alcohol Use Across Adolescence

Long, Elizabeth, Ong, Jue-Sheng, Hwang, Liang-Dar, Savage, Jeanne E., Edwards, Alexis, Prom-Wormley, Elizabeth, Salvatore, Jessica E., Kendler, Kenneth S., Vassileva, Jasmin and Gillespie, Nathan A. (2018). F271. The Moderating Roles of Parental Monitoring and Peer Group Deviance on Polygenic Risk for Alcohol Use Across Adolescence. 2018 Annual Meeting of the Society of Biological Psychiatry, New York, United States, 10-12 May 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.biopsych.2018.02.885

F271. The Moderating Roles of Parental Monitoring and Peer Group Deviance on Polygenic Risk for Alcohol Use Across Adolescence

2018

Conference Publication

Replication and discovery of genetic variants influencing human bitter taste perception

Hwang, Liang-Dar, Gharahkhani, Puya, Zhu, Gu, Gordon, Scott D., Breslin, Paul A. S., Martin, Nicholas G., Reed, Danielle R. and Wright, Margaret J. (2018). Replication and discovery of genetic variants influencing human bitter taste perception. 39th Annual Meeting of the Association for Chemoreception Sciences, Bonita Springs, FL, United States, 26 - 29 April 2017. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/chemse/bjy003

Replication and discovery of genetic variants influencing human bitter taste perception

2017

Journal Article

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study

Ong, Jue-Sheng, Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Martin, Nicholas G., Chenevix-Trench, Georgia, Quinn, Michael C. J., Cornelis, Marilyn C., Gharahkhani, Puya, Webb, Penelope M., MacGregor, Stuart and Ovarian Cancer Association Consortium (2017). Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. International Journal of Epidemiology, 47 (2), 450-459. doi: 10.1093/ije/dyx236

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study

2017

Journal Article

Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue

Lipchock, Sarah V., Spielman, Andrew I., Mennella, Julie A., Mansfield, Corrine J., Hwang, Liang-Dar, Douglas, Jennifer E. and Reed, Danielle R. (2017). Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue. Perception, 46 (3-4), 245-256. doi: 10.1177/0301006616686098

Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue

2017

Journal Article

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing

Guo, Yiran, Hwang, Liang-Dar, Li, Jiankang, Eades, Jason, Yu, Chung Wen, Mansfield, Corrine, Burdick-Will, Alexis, Chang, Xiao, Chen, Yulan, Duke, Fujiko F, Zhang, Jianguo, Fakharzadeh, Steven, Fennessey, Paul, Keating, Brendan J, Jiang, Hui, Hakonarson, Hakon, Reed, Danielle R and Preti, George (2017). Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing. BMC Medical Genetics, 18 (1) 11. doi: 10.1186/s12881-017-0369-8

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing

2016

Journal Article

Is the association between sweet and bitter perception due to genetic variation?

Hwang, Liang-Dar, Breslin, Paul A. S., Reed, Danielle R., Zhu, Gu, Martin, Nicholas G. and Wright, Margaret J. (2016). Is the association between sweet and bitter perception due to genetic variation?. Chemical Senses, 41 (9), 737-744. doi: 10.1093/chemse/bjw083

Is the association between sweet and bitter perception due to genetic variation?

Funding

Current funding

  • 2024 - 2027
    Causal relationship between taste and smell perception and eating behaviour
    ARC Discovery Early Career Researcher Award
    Open grant

Supervision

Availability

Dr Daniel Hwang is:
Available for supervision

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Available projects

  • Develop novel approaches for personalised nutrition using large-scale genetically informative data

    Polygenic risk scores have provided informative predictions for highly heritable traits and has been intergrated into risk prediction models along with traditional clinicial measurements to improvde risk prediction of cardiometabolic disease and other inherited health conditions. This project aims to develop novel polygenic scores specifically for priotising interventions or "personalised intervention" rather than risk prediction.

Supervision history

Current supervision

  • Doctor Philosophy

    Genetics of sensory nutrition - using genetics to understand how taste and olfactory perception influences eating behaviour and health

    Principal Advisor

    Other advisors: Dr Brooke Devlin

  • Doctor Philosophy

    Multi-omic Approaches to Understanding Septic Shock

    Associate Advisor

    Other advisors: Professor David Evans

  • Doctor Philosophy

    Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans

    Associate Advisor

    Other advisors: Dr Olivia Wright, Professor Eugeni Roura

  • Doctor Philosophy

    Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes

    Associate Advisor

    Other advisors: Professor David Evans, Dr Gunn-Helen Moen

  • Doctor Philosophy

    Dietary patterns and molecular mechanisms associated with the pathogenicity of appendicitis in humans

    Associate Advisor

    Other advisors: Dr Olivia Wright, Professor Eugeni Roura

Completed supervision

Media

Enquiries

Contact Dr Daniel Hwang directly for media enquiries about:

  • bitter
  • genetics
  • smell
  • sweet
  • taste

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au