
Overview
Background
Dr Gunn-Helen Moen was awarded her PhD on the "Genetic and environmental etiology of glucose metabolism and cardiometabolic traits during pregnancy and in later life" in 2019 from the Faculty of Medicine at the University of Oslo. After finishing her PhD, she was awarded a Mobility/Marie Sklodowska-Curie Fellowship from the Research Council of Norway and as part of that fellowship she spent two years as a visiting academic at the University of Queensland. She is currently an ARC DECRA fellow at IMB. Her research focus is on using Mendelian randomization to investigate the possible causal effects of maternal environmental exposures during pregnancy on offspring outcomes.
Availability
- Dr Gunn-Helen Moen is:
- Available for supervision
Works
Search Professor Gunn-Helen Moen’s works on UQ eSpace
2020
Journal Article
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
Moen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre I., Wang, Geng, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort. Nature Communications, 11 (1) 5404, 5404. doi: 10.1038/s41467-020-19257-z
2020
Other Outputs
Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study
Moen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre, Neale, Michael C, Freathy, Rachel M, Smith, George Davey, Lawlor, Deborah A, Kirkpatrick, Robert M, Warrington, Nicole M and Evans, David M (2020). Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study. doi: 10.1101/2020.05.04.20091173
2019
Journal Article
Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus
Arora, G. P., Akerlund, M., Brons, C., Moen, G-H, Wasenius, N. S., Sommer, C., Jenum, A. K., Almgren, P., Thaman, R. G., Orho-Melander, M., Eriksson, J., Qvigstad, E., Birkeland, K., Berntorp, K., Vaag, A. A., Groop, L. and Prasad, R. B. (2019). Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus. Journal of Internal Medicine, 286 (2) joim.12903, 192-206. doi: 10.1111/joim.12903
2019
Journal Article
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Warrington, Nicole M., Beaumont, Robin N., Horikoshi, Momoko, Day, Felix R., Helgeland, Øyvind, Laurin, Charles, Bacelis, Jonas, Peng, Shouneng, Hao, Ke, Feenstra, Bjarke, Wood, Andrew R., Mahajan, Anubha, Tyrrell, Jessica, Robertson, Neil R., Rayner, N. William, Qiao, Zhen, Moen, Gunn-Helen, Vaudel, Marc, Marsit, Carmen J., Chen, Jia, Nodzenski, Michael, Schnurr, Theresia M., Zafarmand, Mohammad H., Bradfield, Jonathan P., Grarup, Niels, Kooijman, Marjolein N., Li-Gao, Ruifang, Geller, Frank, Paternoster, Lavinia ... Freathy, Rachel M. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics, 51 (5), 804-814. doi: 10.1038/s41588-019-0403-1
2019
Journal Article
Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization
Evans, David M., Moen, Gunn-Helen, Hwang, Liang-Dar, Lawlor, Debbie A. and Warrington, Nicole M. (2019). Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization. International Journal of Epidemiology, 48 (3), 861-875. doi: 10.1093/ije/dyz019
2019
Journal Article
Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies
Moen, Gunn-Helen, Hemani, Gibran, Warrington, Nicole M. and Evans, David M. (2019). Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies. Behavior Genetics, 49 (3), 327-339. doi: 10.1007/s10519-018-9944-9
2018
Journal Article
Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort
Moen, Gunn-Helen, LeBlanc, Marissa, Sommer, Christine, Prasad, Rashmi B., Lekva, Tove, Normann, Kjersti R., Qvigstad, Elisabeth, Groop, Leif, Birkeland, Kåre I., Evans, David M. and Frøslie, Kathrine F. (2018). Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort. European Journal of Endocrinology, 179 (6), 363-372. doi: 10.1530/EJE-18-0478
2018
Journal Article
Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study
Moen, Gunn-Helen, Qvigstad, Elisabeth, Birkeland, Kåre I., Evans, David M. and Sommer, Christine (2018). Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study. The American Journal of Clinical Nutrition, 108 (2), 398-404. doi: 10.1093/ajcn/nqy101
2017
Journal Article
Local up-regulation of interferon-γ (IFN-γ) following disc herniation is involved in the inflammatory response underlying acute lumbar radicular pain
Moen, Gunn-Helen, Moen, Aurora, Schistad, Elina I. and Gjerstad, Johannes (2017). Local up-regulation of interferon-γ (IFN-γ) following disc herniation is involved in the inflammatory response underlying acute lumbar radicular pain. Cytokine, 97, 181-186. doi: 10.1016/j.cyto.2017.06.005
2017
Journal Article
Mechanisms in endocrinology - Epigenetic modifications and gestational diabetes: a systematic review of published literature
Moen, Gunn-Helen, Sommer, Christine, Prasad, Rashmi B., Sletner, Line, Groop, Leif, Qvigstad, Elisabeth and Birkeland, Kåre I. (2017). Mechanisms in endocrinology - Epigenetic modifications and gestational diabetes: a systematic review of published literature. European Journal of Endocrinology, 176 (5), R247-R267. doi: 10.1530/eje-16-1017
2016
Journal Article
Heavy physical work: cardiovascular load in male construction workers
Lunde, Lars-Kristian, Koch, Markus, Veiersted, Kaj Bo, Moen, Gunn-Helen, Waersted, Morten and Knardahl, Stein (2016). Heavy physical work: cardiovascular load in male construction workers. International Journal of Environmental Research and Public Health, 13 (4) 356, 356. doi: 10.3390/ijerph13040356
Funding
Current funding
Supervision
Availability
- Dr Gunn-Helen Moen is:
- Available for supervision
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Available projects
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Testing effect of environmental exposures on subsequent human generations
Depending on the applicant’s level of experience, they will help develop and/or apply statistical genetics approaches to investigate the possible existence of transgenerational effects on human phenotypes, using cohorts such as the Norwegian HUNT cohort (which has a large number of parent-offspring pairs) and UK Biobank. A PhD is about learning new skills and learning how to do research. Our ideal candidate will have knowledge or keen interest in learning genetics, epidemiology, statistics, unix and shell scripting, and statistical software such as R. You will work closely with an experienced researcher on the project. There will also be possibility for a research stay in Norway during this PhD. The advertised projects are fundamentally quantitative and computer-based, and so evidence of aptitude in these areas is essential. The candidate should also have the ability to design, plan, and execute experiments and be proficient in English, both written and oral.
Supervision history
Current supervision
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Doctor Philosophy
Understanding the genetic epidemiology of women's reproductive health
Associate Advisor
Other advisors: Professor David Evans
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Doctor Philosophy
Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes
Associate Advisor
Other advisors: Dr Daniel Hwang, Professor David Evans
Completed supervision
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2024
Doctor Philosophy
Harnessing Genetically Informative Within-Family Research Designs for Deeper Insights into the Intrauterine Developmental Period and Downstream Effects on Offspring Neurodevelopmental Outcomes
Associate Advisor
Other advisors: Dr Daniel Hwang, Professor David Evans
Media
Enquiries
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