Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

299 works between 1996 and 2025
All (299) Journal Article (263) Book Chapter (2) Conference Publication (33) Other Outputs (1)

181 - 200 of 299 works

2014

Journal Article

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

2014

Journal Article

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial

Kennedy, Glen A., Varelias, Antiopi, Vuckovic, Slavica, Le Texier, Laetitia, Gartlan, Kate H., Zhang, Ping, Thomas, Gethin, Anderson, Lisa, Boyle, Glen, Cloonan, Nicole, Leach, Justine, Sturgeon, Elise, Avery, Judy, Olver, Stuart D., Lor, Mary, Misra, Ashish K., Hutchins, Cheryl, Morton, A. James, Durrant, Simon T. S., Subramoniapillai, Elango, Butler, Jason P., Curley, Cameron I., MacDonald, Kelli P. A., Tey, Siok-Keen and Hill, Geoffrey R. (2014). Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial. The Lancet Oncology, 15 (13), 1451-1459. doi: 10.1016/S1470-2045(14)71017-4

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial

2014

Journal Article

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

Dubovsky, Jason A., Flynn, Ryan, Du, Jing, Harrington, Bonnie K., Zhong, Yiming, Kaffenberger, Benjamin, Yang, Carrie, Towns, William H., Lehman, Amy, Johnson, Amy J., Muthusamy, Natarajan, Devine, Steven M., Jaglowski, Samantha, Serody, Jonathan S., Murphy, William J., Munn, David H., Luznik, Leo, Hill, Geoffrey R., Wong, Henry K., MacDonald, Kelli K. P., Maillard, Ivan, Koreth, John, Elias, Laurence, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Panoskaltsis-Mortari, Angela, Byrd, John C. and Blazar, Bruce R. (2014). Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (11), 4867-4876. doi: 10.1172/JCI75328

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

2014

Journal Article

TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity

Schuster, Iona S., Wikstrom, Matthew E., Brizard, Geraldine, Coudert, Jerome D., Estcourt, Marie J., Manzur, Mitali, O'Reilly, Lorraine A., Smyth, Mark J., Trapani, Joseph A., Hill, Geoffrey R., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2014). TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity. Immunity, 41 (4), 646-656. doi: 10.1016/j.immuni.2014.09.013

TRAIL+ NK Cells Control CD4+ T Cell Responses during Chronic Viral Infection to Limit Autoimmunity

2014

Journal Article

Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis

Smith, Daniel J., Hill, Geoffrey R., Bell, Scott C. and Reid, David W. (2014). Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis. PLoS ONE, 9 (10) e109891, 1-8. doi: 10.1371/journal.pone.0109891

Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis

2014

Journal Article

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease

Alexander K.A., Flynn R., Lineburg K.E., Kuns R.D., Teal B.E., Olver S.D., Lor M., Raffelt N.C., Koyama M., Leveque L., Le Texier L., Melino M., Markey K.A., Varelias A., Engwerda C., Serody J.S., Janela B., Ginhoux F., Clouston A.D., Blazar B.R., Hill G.R. and MacDonald K.P.A. (2014). CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (10), 4266-4280. doi: 10.1172/JCI75935

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease

2014

Journal Article

The biology of graft-versus-host disease: experimental systems instructing clinical practice

Markey, Kate A., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2014). The biology of graft-versus-host disease: experimental systems instructing clinical practice. Blood, 124 (3), 354-362. doi: 10.1182/blood-2014-02-514745

The biology of graft-versus-host disease: experimental systems instructing clinical practice

2014

Journal Article

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

Flynn, Ryan, Du, Jing, Veenstra, Rachelle G., Reichenbach, Dawn K., Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Freeman, Gordon J., Serody, Jonathan S., Murphy, William J., Munn, David H., Sarantopoulos, Stefanie, Luznik, Leo, Maillard, Ivan, Koreth, John, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Dubovsky, Jason A., Byrd, John C., MacDonald, Kelli P., Hill, Geoff R. and Blazar, Bruce R. (2014). Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood, 123 (25), 3988-3998. doi: 10.1182/blood-2014-03-562231

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

2014

Journal Article

Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity

Haque, Ashraful, Best, Shannon E., De Oca, Marcela Montes, James, Kylie R., Ammerdorffer, Anne, Edwards, Chelsea L., De Labastida Rivera, Fabian, Amante, Fiona H., Bunn, Patrick T., Sheel, Meru, Sebina, Ismail, Koyama, Motoko, Varelias, Antiopi, Hertzog, Paul J., Kalinke, Ulrich, Gun, Sin Yee, Renia, Laurent, Ruedl, Christiane, MacDonald, Kelli P.A., Hill, Geoffrey R. and Engwerda, Christian R. (2014). Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity. Journal of Clinical Investigation, 124 (6), 2483-2496. doi: 10.1172/JCI70698

Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity

2014

Journal Article

Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigen

Markey, Kate A., Koyama, Motoko, Gartlan, Kate H., Leveque, Lucie, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2014). Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigen. Journal of Immunology, 192 (11), 5426-5433. doi: 10.4049/jimmunol.1302490

Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigen

2014

Journal Article

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

MacDonald, Kelli P. A., Le Texier, Laetitia, Zhang, Ping, Morris, Helen, Kuns, Rachel D., Lineburg, Katie E., Leveque, Lucie, Don, Alistair L., Markey, Kate A., Vuckovic, Slavica, Bagger, Frederik O., Boyle, Glen M., Blazar, Bruce R. and Hill, Geoffrey R. (2014). Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10. Journal of Immunology, 192 (7), 3180-3189. doi: 10.4049/jimmunol.1302315

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

2014

Journal Article

Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host disease

Curley, C., Hill, G. R., McLean, A. and Kennedy, G. A. (2014). Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host disease. International Journal of Laboratory Hematology, 36 (2), 197-204. doi: 10.1111/ijlh.12153

Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host disease

2014

Journal Article

Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning

Koyama, M., Hashimoto, D., Nagafuji, K., Eto, T., Ohno, Y., Aoyama, K., Iwasaki, H., Miyamoto, T., Hill, G.R., Akashi, K. and Teshima, T. (2014). Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning. Bone Marrow Transplantation, 49 (1), 110-115. doi: 10.1038/bmt.2013.134

Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning

2014

Journal Article

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

Wikstrom, Matthew E., Khong, Andrea, Fleming, Peter, Kuns, Rachel, Hertzog, Paul J., Frazer, Ian H., Andoniou, Christopher E., Hill, Geoffrey R. and Degli-Esposti, Mariapia A. (2014). The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals. European Journal of Immunology, 44 (2), 409-419. doi: 10.1002/eji.201243109

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

2013

Journal Article

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria

Horne-Debets, Joshua M., Faleiro, Rebecca, Karunarathne, Deshapriya S., Liu, Xue Q., Lineburg, Katie E., Poh, Chek Meng, Grotenbreg, Gijsbert M., Hill, Geoffrey R., MacDonald, Kelli P. A., Good, Michael F., Renia, Laurent, Ahmed, Rafi, Sharpe, Arlene H. and Wykes, Michelle N. (2013). PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria. Cell Reports, 5 (5), 1204-1213. doi: 10.1016/j.celrep.2013.11.002

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria

2013

Journal Article

Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation

Andani, Rafiq, Robertson, Ivan, MacDonald, Kelli P. A., Durrant, Simon, Hill, Geoffrey R. and Khosrotehrani, Kiarash (2013). Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation. Experimental Dermatology, Accepted Article (1), 1-11. doi: 10.1111/exd.12301

Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation

2013

Journal Article

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

Zhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

2013

Journal Article

Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications

Tey, Siok-Keen, Kennedy, Glen A., Cromer, Deborah, Davenport, Miles P., Walker, Susan, Jones, Linda I., Crough, Tania, Durrant, Simon T., Morton, James A., Butler, Jason P., Misra, Ashish K., Hill, Geoffrey R. and Khanna, Rajiv (2013). Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications. PLoS ONE, 8 (10) e74744, e74744. doi: 10.1371/journal.pone.0074744

Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications

2013

Journal Article

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus.

Ong, Monique L., Wikstrom, Matthew E., Fleming, Peter, Estcourt, Marie J., Hertzog, Paul J., Hill, Geoffrey R., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2013). CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus.. Blood, 122 (1), 55-60. doi: 10.1182/blood-2012-12-471227

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus.

2013

Journal Article

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages

Handoko, Herlina Y., Rodero, Mathieu P., Boyle, Glen M., Ferguson, Blake, Engwerda, Christian, Hill, Geoff, Muller, H. Konrad, Khosrotehrani, Kiarash and Walker, Graeme J. (2013). UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages. Journal of Investigative Dermatology, 133 (7), 1803-1812. doi: 10.1038/jid.2013.9

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

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