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2023

Conference Publication

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice

Adams, Rachael C., Carter-Cusack, Dylan, Llanes, Genesis T., Hunter, Christopher R., Vinnakota, Janaki Manoja, Ruitenberg, Marc, Vukovic, Jana, Bertolino, Patrick, Chand, Kirat K., Wixey, Julie A., Nayler, Samuel P., Hill, Geoffrey R., Furlan, Scott N., Zeiser, Robert and MacDonald, Kelli P. A. (2023). CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice. 65th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 9-12 December 2023. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2023-184841

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice

2023

Conference Publication

Type-1 regulatory T cells are critical for curative immunotherapy outcomes

Zhang, Ping, Gartlan, Kate H., Minnie, Simone A., Yeh, Albert, Takahashi, Shuichiro, Atilla, Erden, Nemychenkov, Nicole S., Boiko, Julie R., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Ensbey, Kathleen S., Koyama, Motoko, Furlan, Scott N. and Hill, Geoffrey R. (2023). Type-1 regulatory T cells are critical for curative immunotherapy outcomes. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.173.11

Type-1 regulatory T cells are critical for curative immunotherapy outcomes

2023

Conference Publication

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

Geramita, Emily, Ventura, Kedwin, Bhise, Shruti, Moore, Erika, Krakow, Elizabeth F., Hill, Geoffrey R., Furlan, Scott N., Shlomchik, Warren D. and Ito, Sawa (2023). Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00122-7

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

2023

Conference Publication

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

Boiko, Julie R., Ensbey, Kathleen S., Schmidt, Christine R., Waltner, Olivia G., Minnie, Simone A., Furlan, Scott N. and Hill, Geoffrey R. (2023). Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00389-5

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

2022

Conference Publication

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

Zamora, Danniel, Krantz, Elizabeth M., Joncas-Schronce, Laurel, Akoto, Brenda, Stevens-Ayers, Terry L., Bender Ignacio, Rachel A., Hill, Joshua A., Degli-Esposti, Mariapia, Hill, Geoffrey and Boeckh, Michael J. (2022). Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT). IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.549

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

2022

Conference Publication

CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation

Zamora, Danniel, Xie, Hu, Hill, Joshua A., Duke, Elizabeth, Green, Margaret, Kimball, Louise E., Holmberg, Leona, Waghmare, Alpana, Greninger, Alexander L., Jerome, Keith R., Flowers, Mary, Hill, Geoffrey, Leisenring, Wendy M. and Boeckh, Michael J. (2022). CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation. IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.683

CMV Reactivation in Hematopoietic Cell Transplant Candidates: A Novel Risk Factor for Post-transplant Reactivation

2022

Conference Publication

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

Hill, Joshua A., Lee, Yeon Joo, Vande Vusse, Lisa K., Xie, Hu, Lisa Chung, E., Keane-Candib, Jacob, Waghmare, Alpana, Cheng, Guang-Shing, Zhu, Haiying, Huang, Meei-Li, Hill, Geoffrey, Jerome, Keith R., Gharib, Sina A, Leisenring, Wendy M., Zerr, Danielle M., Dadwal, Sanjeet S. and Boeckh, Michael J. (2022). A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients. IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.1716

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

2021

Conference Publication

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

Henden, Andrea S., Robb, Renee, Forero, Adriana, Kuns, Rachel D., Ensbey, Kathleen S., Chang, Karshing, Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nic, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey (2021). Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd. 2021 TCT Meetings of ASTCT and CIBMTR, Online, 8-12 February 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2666-6367(21)00107-x

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

2020

Conference Publication

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

Minnie, Simone A., Kuns, Rachel D., Ensbey, Kathleen S., Samson, Luke D., Chesi, Marta, Gartlan, Kate H., Smyth, Mark J., Vuckovic, Slavica and Hill, Geoffrey R. (2020). Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.30

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

2020

Conference Publication

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

Aguilar, Ethan George, Rhee, Stephanie, Thangavelu, Govindarajan, Loschi, Michael, Paz, Katelyn, Saha, Asim, Ly, Joanna, Sage, Peter, Sharpe, Arlene H., Maillard, Ivan, Murphy, William J., Serody, Jonathan S., Jin, Suji, Wagers, Sara Bolivar, Nicholls, Jemma, Hill, Geoffrey, MacDonald, Kelli P.A., Compeer, Ewoud, Dustin, Michael, O’Connor, Roddy, Sparwasser, Tim and Blazar, Bruce R. (2020). Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD). Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.2

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

2020

Conference Publication

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

Gartlan, Kate H., Wilkinson, Andrew, Chang, Karshing, Kuns, Rachel D., Henden, Andrea, Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew, Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica and Hill, Geoffrey R. (2020). Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.33

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

2019

Conference Publication

B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality

Saha, Asim, Taylor, Patricia A., Lees, Christopher J., Panoskaltsis-Mortari, Angela, Osborn, Mark J., Feser, Colby J., Thangavelu, Govindarajan, Melchinger, Wolfgang, Refaeli, Yosef, Hill, Geoffrey R., Munn, David H., Serody, Jonathan S., Maillard, Ivan, Kreymborg, Katharina, van den Brink, Marcel, Dong, Chen, Huang, Shuyu, Zang, Xingxing, Allison, James P, Zeiser, Robert and Blazar, Bruce R. (2019). B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.10

B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality

2019

Conference Publication

Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation

Zaiken, Michael C., Flynn, Ryan, Paz, Katelyn, Rhee, Stephanie, Park, Paul, Hemming, Matthew, Sage, Peter, Sharpe, Arlene, Luznik, Leonard, Mailard, Ivan, Hill, Geoffrey R., MacDonald, Kelli, Serody, Jonathon, Cutler, Corey, Koreth, John, Miklos, David, Antin, Joseph, Soiffer, Robert, Ritz, Jerome, Bradner, Jay, Qi, Jun and Blazar, Bruce R. (2019). Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.42

Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation

2019

Conference Publication

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

2018

Conference Publication

Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878

Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study

2018

Conference Publication

Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878

Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study

2018

Conference Publication

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

Varelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.15

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

2018

Conference Publication

Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium

Minnie, Simone, Vuckovic, Slavica, Smith, David, Gartlan, Kate H., Watkins, Thomas S., Kuns, Rachel D., Guillerey, Camille, Chesi, Marta, Markey, Kate A., Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.19

Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium

2018

Conference Publication

Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo

Wilkinson, Andrew N., Kuns, Rachel D., Varelias, Antiopi, Vuckovic, Slavica, Rose-John, Stefan, Gartlan, Kate H. and Hill, Geoffrey R. (2018). Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.2

Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo

2017

Conference Publication

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P.A., Hugenholtz, Philip and Hill, Geoff R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Immunology 2017™ Meeting, Washington, DC United States, 12-16 May 2017. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.198.supp.82.8

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome