Overview
Availability
- Professor Steven Lane is:
- Available for supervision
Works
Search Professor Steven Lane’s works on UQ eSpace
2024
Journal Article
Single Cell Genotype-Phenotype Analysis Demonstrates That Post-MPN AML Is Driven By Clonal Evolution and Loss of Transcriptional Heterogeneity within Stem Cell Compartments
Straube, Jasmin, Grabek, Julian, Cooper, Leanne, Haldar, Rohit, McNamara, Caroline, Ross, David M, Perkins, Andrew, Bywater, Megan and Lane, Steven W (2024). Single Cell Genotype-Phenotype Analysis Demonstrates That Post-MPN AML Is Driven By Clonal Evolution and Loss of Transcriptional Heterogeneity within Stem Cell Compartments. Blood, 144 (Supplement 1), 1346-1346. doi: 10.1182/blood-2024-199841
2024
Journal Article
Durable Responses Observed in Chronic Myelomonocytic Leukemia Treated with Lenzilumab and Azacitidine
Hiwase, Devendra, Ross, David M, Yeung, David T, Yong, Agnes S. M., Lane, Steven W, Brown, Anna, Fong, Chun Yew, Hughes, Timothy P, Reynolds, John and Thomas, Daniel (2024). Durable Responses Observed in Chronic Myelomonocytic Leukemia Treated with Lenzilumab and Azacitidine. Blood, 144 (Supplement 1), 1006-1006. doi: 10.1182/blood-2024-202867
2024
Journal Article
High Dose Ascorbate Reduces Interleukin-1 Beta Secretion in TET2 Mutant Monocytes and Demonstrates Excellent Safety and Tolerability in CMML Patients in Combination with Azacitidine
Kamel, Maha M, Robinson, Nirmal, Kutyna, Monika, Lim, Kelly, Thompson-Peach, Chloe, Lane, Steven W, Yeung, David T, Yong, Agnes S. M., Ross, David M, Hiwase, Devendra and Thomas, Daniel (2024). High Dose Ascorbate Reduces Interleukin-1 Beta Secretion in TET2 Mutant Monocytes and Demonstrates Excellent Safety and Tolerability in CMML Patients in Combination with Azacitidine. Blood, 144 (Supplement 1), 1817-1817. doi: 10.1182/blood-2024-204177
2024
Journal Article
Update of the Ascend-CML Study of Frontline Asciminib: High Rate of Optimal Response and Resistance Due to Mutations Is Rare
Yeung, David T, Shanmuganathan, Naranie, Yong, Agnes S. M., Shortt, Jake, Chee, Lynette C.Y., Vialla, Nicholas, Cunningham, Ilona, Ross, David M, D'Souza, Alwyn, Wright, Matthew P.F., Harrup, Rosemary, Forsyth, Cecily, Filshie, Robin, Lane, Steven W, Browett, Peter J., Grove, Carolyn S., Walia, Mannu, Branford, Susan, Reynolds, John, Grigg, Andrew P and Hughes, Timothy P (2024). Update of the Ascend-CML Study of Frontline Asciminib: High Rate of Optimal Response and Resistance Due to Mutations Is Rare. Blood, 144 (Supplement 1), 476-476. doi: 10.1182/blood-2024-201218
2024
Journal Article
Overcoming Ven/Aza Resistance through Imetelstat-Mediated Lipophagy in Acute Myeloid Leukemia
Bruedigam, Claudia, Dulatre, Eunice Anne, Lee, Carol, Porter, Amy H, Lim, Elisa LSP, Shi, Alexander Z, Hodson, Mark P, Heidel, Florian H. and Lane, Steven W (2024). Overcoming Ven/Aza Resistance through Imetelstat-Mediated Lipophagy in Acute Myeloid Leukemia. Blood, 144 (Supplement 1), 52-52. doi: 10.1182/blood-2024-206473
2024
Journal Article
<i>Dnmt3a</i> Mutation Promotes Expansion of a Quiescent Myeloid Progenitor Population in <i>Npm1c-Flt3ITD</i> Acute Myeloid Leukemia
Tavakoli, Paniz, Bywater, Megan, Straube, Jasmin, Ling, Victoria, Cooper, Emily, Haldar, Rohit, Janardhanan, Yashaswini, Cooper, Leanne, Bruedigam, Claudia, Grove, Carolyn S. and Lane, Steven W (2024). Dnmt3a Mutation Promotes Expansion of a Quiescent Myeloid Progenitor Population in Npm1c-Flt3ITD Acute Myeloid Leukemia. Blood, 144 (Supplement 1), 1347-1347. doi: 10.1182/blood-2024-201250
2024
Journal Article
CBL Variants in Chronic Myelomonocytic Leukemia Exhibit a Complex Sub-Clone Architecture with a High Frequency of RING Domain Mutations Sufficient to Induce GM-CSF Hypersensitivity
Lim, Kelly, Kutyna, Monika, Kan, Winnie, Lopez, Angel F., Brown, Anna, Yong, Agnes S. M., Lane, Steven W, Fong, Chun Yew, Hughes, Timothy P, Yeung, David T, Ross, David M, Hiwase, Devendra and Thomas, Daniel (2024). CBL Variants in Chronic Myelomonocytic Leukemia Exhibit a Complex Sub-Clone Architecture with a High Frequency of RING Domain Mutations Sufficient to Induce GM-CSF Hypersensitivity. Blood, 144 (Supplement 1), 3196-3196. doi: 10.1182/blood-2024-202682
2024
Journal Article
CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting
Lim, Kelly, Kan, Winnie L., Nair, Pramod C., Kutyna, Monika, Lopez, Angel F., Hercus, Timothy, Ross, David M., Lane, Steven, Fong, Chun Yew, Brown, Anna, Yong, Agnes, Yeung, David, Hughes, Timothy, Hiwase, Devendra and Thomas, Daniel (2024). CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting. PLoS One, 19 (9 September) e0310641, 1-19. doi: 10.1371/journal.pone.0310641
2024
Journal Article
Identifying disease-modifying potential in myelofibrosis clinical trials
Ross, David M, Lane, Steven W and Harrison, Claire N. (2024). Identifying disease-modifying potential in myelofibrosis clinical trials. Blood Journal, 144 (16), 1679-1688. doi: 10.1182/blood.2024024220
2024
Journal Article
Asciminib Monotherapy as Frontline Treatment of Chronic-Phase Chronic Myeloid Leukemia: Results from the ASCEND Study
Yeung, David T., Shanmuganathan, Naranie, Reynolds, John, Branford, Susan, Walia, Mannu, Yong, Agnes SM, Shortt, Jake, Chee, Lynette, Viiala, Nicholas, Cunningham, Ilona, Ross, David M, D'Souza, Alwyn Bernard, Wright, Matthew, Harrup, Rosemary Anne, Forsyth, Cecily Jane, Filshie, Robin, Lane, Steven W, Browett, Peter J, Grove, Carolyn S, Grigg, Andrew A and Hughes, Timothy P (2024). Asciminib Monotherapy as Frontline Treatment of Chronic-Phase Chronic Myeloid Leukemia: Results from the ASCEND Study. Blood Journal, 144 (19), 1993-2001. doi: 10.1182/blood.2024024657
2024
Conference Publication
3035 – INTERFERON ALPHA THERAPY ATTENUATES LEUKAEMIC TRANSFORMATION IN JAK2V617F-DRIVEN MPN WITH TRP53-LOSS
Bywater, Megan, Zhang, Ranran, Grabek, Julian, Halder, Rohit, Janardhanan, Yashaswini, Cooper, Leanne, Cooper, Emily, Ross, David, Straube, Jasmin and Lane, Steven (2024). 3035 – INTERFERON ALPHA THERAPY ATTENUATES LEUKAEMIC TRANSFORMATION IN JAK2V617F-DRIVEN MPN WITH TRP53-LOSS. EXPHEM 2024, Philadelphia, PA, United States: Elsevier BV. doi: 10.1016/j.exphem.2024.104357
2024
Conference Publication
6471 Performance of eight different severity scores to predict critical care admission in paediatric inpatients treated for sepsis: a retrospective cohort study
Deef, Minnah, Bracken, Abbey, Lane, Steven, Gittings, Robert, Curran, Rachel, Foreman, Rachael, Gawne, Andrew, Carter, Bernie, Saron, Holly, Eyton-Chong, Chin-Kien, Mehta, Fulya, Siner, Sarah, Lambert, Caroline, Sefton, Gerri and Carrol, Enitan D (2024). 6471 Performance of eight different severity scores to predict critical care admission in paediatric inpatients treated for sepsis: a retrospective cohort study. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi: 10.1136/archdischild-2024-rcpch.491
2024
Journal Article
Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality
Scho, Jeremy, Abrams, Simon T., Jenkins, Rosalind, Lane, Steven, Wang, Guozheng and Toh, Cheng-Hock (2024). Microclots, as defined by amyloid-fibrinogen aggregates, predict risks of disseminated intravascular coagulation and mortality. Blood Advances, 8 (10), 2499-2508. doi: 10.1182/bloodadvances.2023012473
2024
Journal Article
Autophagy prevents graft failure during murine Graft versus Host Disease
Lineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972
2024
Journal Article
Survival for the fittest: guadecitabine in rel/ref AML
Sheehy, Joshua and Lane, Steven W. (2024). Survival for the fittest: guadecitabine in rel/ref AML. Blood Advances, 8 (8), 2018-2019. doi: 10.1182/bloodadvances.2024012569
2024
Journal Article
Low iodine nutrition knowledge in Chinese breastfeeding women despite adequate iodine status
Liu, Shuchang, Sharp, Andrew, Lane, Steven, Villanueva, Elmer V., Lu, Zhiliang and Ma, Zheng Feei (2024). Low iodine nutrition knowledge in Chinese breastfeeding women despite adequate iodine status. Nutrients, 16 (4) 491, 1-14. doi: 10.3390/nu16040491
2024
Journal Article
Australia and New Zealand consensus position statement: use of COVID-19 therapeutics in patients with haematological malignancies
Campbell, Ashlea, Teh, Benjamin, Mulligan, Stephen, Ross, David M., Weinkove, Robert, Gilroy, Nicole, Gangatharan, Shane, Prince, Henry Miles, Szer, Jeff, Trotman, Judith, Lane, Steven, Dickinson, Michael, Quach, Hang, Enjeti, Anoop K., Ku, Matthew, Gregory, Gareth, Hapgood, Gregory, Ho, Phoebe Joy, Cochrane, Tara, Cheah, Chan, Greenwood, Matthew, Latimer, Maya, Berkahn, Leanne, Wight, Joel, Armytage, Tasman, Diamond, Peter, Tam, Constantine S. and Hamad, Nada (2024). Australia and New Zealand consensus position statement: use of COVID-19 therapeutics in patients with haematological malignancies. Internal Medicine Journal, 54 (2), 328-336. doi: 10.1111/imj.16303
2024
Journal Article
Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia
Bruedigam, Claudia, Porter, Amy H., Song, Axia, Vroeg in de Wei, Gerjanne, Stoll, Thomas, Straube, Jasmin, Cooper, Leanne, Cheng, Guidan, Kahl, Vivian F. S., Sobinoff, Alexander P., Ling, Victoria Y., Jebaraj, Billy Michael Chelliah, Janardhanan, Yashaswini, Haldar, Rohit, Bray, Laura J., Bullinger, Lars, Heidel, Florian H., Kennedy, Glen A., Hill, Michelle M., Pickett, Hilda A., Abdel-Wahab, Omar, Hartel, Gunter and Lane, Steven W. (2024). Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia. Nature Cancer, 5 (1), 47-65. doi: 10.1038/s43018-023-00653-5
2024
Journal Article
A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study
Qurashi, Inti, Chaudhry, Imran B., Khoso, Ameer B., Husain, Muhammad Omair, Hafeez, Danish, Kiran, Tayyeba, Lane, Steven, Naqvi, Haider A., Minhas, Fareed A., Nizami, Asad Tamizuddin, Razzaque, Bushra, Bokhari, Sumira Qambar, Yung, Alison R., Deakin, Bill and Husain, Nusrat (2024). A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study. Brain Behavior and Immunity, 115, 609-616. doi: 10.1016/j.bbi.2023.10.025
2023
Journal Article
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia
Tubio-Santamaria, Nuria, Jayavelu, Ashok Kumar, Schnoeder, Tina M., Eifert, Theresa, Hsu, Chen-Jen, Perner, Florian, Zhang, Qirui, Wenge, Daniela V., Hansen, Fynn M., Kirkpatrick, Joanna M., Jyotsana, Nidhi, Lane, Steven W., von Eyss, Bjoern, Deshpande, Aniruddha J., Kuehn, Michael W. M., Schwaller, Juerg, Cammann, Clemens, Seifert, Ulrike, Ebstein, Frederic, Krueger, Elke, Hochhaus, Andreas, Heuser, Michael, Ori, Alessandro, Mann, Matthias, Armstrong, Scott A. and Heidel, Florian H. (2023). Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia. Molecular Cancer, 22 (1) 196. doi: 10.1186/s12943-023-01907-7
Supervision
Availability
- Professor Steven Lane is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Genomic drivers of progression of MPN to AML
Principal Advisor
-
Doctor Philosophy
Leukemic transformation STEMming from myeloproliferative neoplasm: Resolving the loss of stem cell heterogeneity
Principal Advisor
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Doctor Philosophy
Targeting the cancer-immune cross talk in Acute Myeloid Leukaemia
Associate Advisor
Completed supervision
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2024
Doctor Philosophy
CRISPR-Cas9 approaches to model Myeloproliferative Neoplasms in vivo.
Principal Advisor
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2019
Doctor Philosophy
Factors that regulate response to chemotherapy in myelodysplastic syndromes and acute myeloid leukaemia
Principal Advisor
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2017
Doctor Philosophy
Maintenance of blood stem cells and the development of haematological malignancies
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2024
Doctor Philosophy
Targeting the cancer-immune cross talk in Acute Myeloid Leukaemia
Associate Advisor
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2022
Doctor Philosophy
Extracellular vesicle-associated miRNAs and proteins as biomarkers of Non-Small Cell Lung Cancer
Associate Advisor
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2019
Doctor Philosophy
Anti-leukaemia effect of Interferons
Associate Advisor
Other advisors: Associate Professor Kate Gartlan, Honorary Professor Geoffrey Hill
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2017
Doctor Philosophy
Combating Human Immunodeficiency Virus Replication by Gene Therapy
Associate Advisor
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Media
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