Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

278 works between 1996 and 2024
All (278) Journal Article (250) Book Chapter (2) Conference Publication (26)

1 - 20 of 278 works

2024

Journal Article

CMV Reactivation during Pre-Transplantation Evaluation: A Novel Risk Factor for Post-Transplantation CMV Reactivation

Zamora, Danniel, Xie, Hu, Sadowska-Klasa, Alicja, Kampouri, Eleftheria, Biernacki, Melinda A, Ueda Oshima, Masumi, Duke, Elizabeth R, Green, Margaret L., Kimball, Louise, Holmberg, Leona A, Waghmare, Alpana, Greninger, Alexander L, Jerome, Keith R, Hill, Geoffrey R, Hill, Joshua A, Leisenring, Wendy M and Boeckh, Michael J (2024). CMV Reactivation during Pre-Transplantation Evaluation: A Novel Risk Factor for Post-Transplantation CMV Reactivation. Blood Advances, 8 (17), 4568-4580. doi: 10.1182/bloodadvances.2023012234

CMV Reactivation during Pre-Transplantation Evaluation: A Novel Risk Factor for Post-Transplantation CMV Reactivation

2024

Journal Article

Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

Yeh, Albert C., Koyama, Motoko, Waltner, Olivia G., Minnie, Simone A., Boiko, Julie R., Shabaneh, Tamer B., Takahashi, Shuichiro, Zhang, Ping, Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Nelson, Ethan, Bhise, Shruti S., Stevens, Andrew R., Goodpaster, Tracy, Chakka, Saranya, Furlan, Scott N., Markey, Kate A., Bleakley, Marie E., Elson, Charles O., Bradley, Philip H. and Hill, Geoffrey R. (2024). Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation. Immunity, 57 (7), 1648-1664.e9. doi: 10.1016/j.immuni.2024.05.018

Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation

2024

Journal Article

IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation

Zhang, Ping, Fleming, Peter, Andoniou, Christopher E., Waltner, Olivia G., Bhise, Shruti S., Martins, Jose Paulo, McEnroe, Benjamin A., Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D., Ekwe, Adaeze P., Henden, Andrea S., Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Minnie, Simone A., Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D., Koyama, Motoko, Furlan, Scott N., Kennedy, Glen A., Ward, E Sally, Degli-Esposti, Mariapia A. ... Tey, Siok-Keen (2024). IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. Journal of Clinical Investigation, 134 (7) e174184. doi: 10.1172/jci174184

IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation

2024

Journal Article

Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells

Ekwe, Adaeze Precious, Au, Raymond, Zhang, Ping, McEnroe, Benjamin, Tan, Mei Ling, Saldan, Alda, Henden, Andrea S., Hutchins, Cheryl, Henderson, Ashleigh, Mudie, Kari, Kerr, Keri, Fuery, Madonna, Kennedy, Glen A., Hill, Geoffrey R. and Tey, Siok-Keen (2024). Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells. Cytotherapy, 26 (7), 719-728. doi: 10.1016/j.jcyt.2024.02.023

Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells

2024

Journal Article

Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Ng, Susanna S., De Labastida Rivera, Fabian, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C. M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., Montes de Oca, Marcela, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona H. ... Engwerda, Christian R. (2024). Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 25 (4), 716-716. doi: 10.1038/s41590-024-01770-8

Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

2024

Journal Article

Autophagy prevents graft failure during murine Graft versus Host Disease

Lineburg, Katie E, Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W, Hill, Geoffrey R, Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972

Autophagy prevents graft failure during murine Graft versus Host Disease

2024

Journal Article

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Takahashi, Shuichiro, Minnie, Simone A., Ensbey, Kathleen S., Schmidt, Christine R., Sekiguchi, Tomoko, Legg, Samuel R. W., Zhang, Ping, Koyama, Motoko, Olver, Stuart D., Collinge, Alika D., Keshmiri, Sara, Comstock, Melissa L., Varelias, Antiopi, Green, Damian J. and Hill, Geoffrey R. (2024). Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Blood, 143 (16), 1656-1669. doi: 10.1182/blood.2023022000

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

2023

Journal Article

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice

Adams, Rachael C, Carter-Cusack, Dylan, Llanes, Genesis T, Hunter, Christopher R., Vinnakota, Janaki Manoja, Ruitenberg, Marc J, Vukovic, Jana, Bertolino, Patrick, Chand, Kirat K., Wixey, Julie A., Nayler, Samuel P., Hill, Geoffrey R, Furlan, Scott N, Zeiser, Robert and MacDonald, Kelli P.A. (2023). CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice. Blood Journal, 142 (Supplement 1), 2052-2052. doi: 10.1182/blood.2023022040

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice

2023

Conference Publication

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice

Adams, Rachael C., Carter-Cusack, Dylan, Llanes, Genesis T., Hunter, Christopher R., Vinnakota, Janaki Manoja, Ruitenberg, Marc, Vukovic, Jana, Bertolino, Patrick, Chand, Kirat K., Wixey, Julie A., Nayler, Samuel P., Hill, Geoffrey R., Furlan, Scott N., Zeiser, Robert and MacDonald, Kelli P. A. (2023). CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice. 65th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 9-12 December 2023. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2023-184841

CSF1R inhibition promotes neuroinflammation and behavioural deficits during graftversus-host disease in mice

2023

Journal Article

Chronic GvHD NIH consensus project biology task force: evolving path to personalized treatment of chronic GvHD

Buxbaum, Nataliya Prokopenko, Socié, Gerard, Hill, Geoffrey R, MacDonald, Kelli PA, Tkachev, Victor, Teshima, Takanori, Lee, Stephanie J, Ritz, Jerome, Sarantopoulos, Stefanie, Luznik, Leo, Zeng, Defu, Paczesny, Sophie, Martin, Paul J., Pavletic, Steven Z, Schultz, Kirk R and Blazar, Bruce R. (2023). Chronic GvHD NIH consensus project biology task force: evolving path to personalized treatment of chronic GvHD. Blood Advances, 7 (17), 4886-4902. doi: 10.1182/bloodadvances.2022007611

Chronic GvHD NIH consensus project biology task force: evolving path to personalized treatment of chronic GvHD

2023

Journal Article

Treg amelioration of GVHD following allo/xeno-HSCT using mobilized mouse and human peripheral blood donors

Barreras, Henry, Copsel, Sabrina N., Bader, Cameron S., Ding, Ying, Wolf, Dietlinde, Cash, Charles, Stacey, Caleb J., Benjamin, Cara, Seavey, Mathew M, Wolf, Jeffrey, Jasuja, Rahul R, Pfeiffer, Brent, Hill, Geoffrey R., Komanduri, Krishna V., Jurecic, Roland, Malek, Thomas R. and Levy, Robert B. (2023). Treg amelioration of GVHD following allo/xeno-HSCT using mobilized mouse and human peripheral blood donors. Transplantation and Cellular Therapy, 29 (5), 341.e1-341.e9. doi: 10.1016/j.jtct.2023.02.015

Treg amelioration of GVHD following allo/xeno-HSCT using mobilized mouse and human peripheral blood donors

2023

Conference Publication

Type-1 regulatory T cells are critical for curative immunotherapy outcomes

Zhang, Ping, Gartlan, Kate H., Minnie, Simone A., Yeh, Albert, Takahashi, Shuichiro, Atilla, Erden, Nemychenkov, Nicole S., Boiko, Julie R., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Ensbey, Kathleen S., Koyama, Motoko, Furlan, Scott N. and Hill, Geoffrey R. (2023). Type-1 regulatory T cells are critical for curative immunotherapy outcomes. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.173.11

Type-1 regulatory T cells are critical for curative immunotherapy outcomes

2023

Journal Article

Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation

Ueda Oshima, Masumi, Xie, Hu, Zamora, Danniel, Flowers, Mary E., Hill, Geoffrey R, Mielcarek, Marco, Sandmaier, Brenda M, Gooley, Theodore A and Boeckh, Michael J. (2023). Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation. Blood Advances, 7 (8), 1394-1403. doi: 10.1182/bloodadvances.2022009112

Impact of GVHD prophylaxis on CMV reactivation and disease after HLA-matched peripheral blood stem cell transplantation

2023

Journal Article

Oncogenic drivers dictate immune control of acute myeloid leukemia

Austin, Rebecca J., Straube, Jasmin, Halder, Rohit, Janardhanan, Yashaswini, Bruedigam, Claudia, Witkowski, Matthew, Cooper, Leanne, Porter, Amy, Braun, Matthias, Souza-Fonseca-Guimaraes, Fernando, Minnie, Simone A., Cooper, Emily, Jacquelin, Sebastien, Song, Axia, Bald, Tobias, Nakamura, Kyohei, Hill, Geoffrey R., Aifantis, Iannis, Lane, Steven W. and Bywater, Megan J. (2023). Oncogenic drivers dictate immune control of acute myeloid leukemia. Nature Communications, 14 (1) 2155, 1-14. doi: 10.1038/s41467-023-37592-9

Oncogenic drivers dictate immune control of acute myeloid leukemia

2023

Journal Article

Infection induces tissue-resident memory NK cells that safeguard tissue health

Schuster, Iona S., Sng, Xavier Y. X., Lau, Colleen M., Powell, David R., Weizman, Orr-El, Fleming, Peter, Neate, Georgia E. G., Voigt, Valentina, Sheppard, Sam, Maraskovsky, Andreas I., Daly, Sheridan, Koyama, Motoko, Hill, Geoffrey R., Turner, Stephen J., O’Sullivan, Timothy E., Sun, Joseph C., Andoniou, Christopher E. and Degli-Esposti, Mariapia A. (2023). Infection induces tissue-resident memory NK cells that safeguard tissue health. Immunity, 56 (3), 531-546.e6. doi: 10.1016/j.immuni.2023.01.016

Infection induces tissue-resident memory NK cells that safeguard tissue health

2023

Journal Article

A novel RIPK1 inhibitor attenuates GVHD

Hill, Geoffrey R. and Koyama, Motoko (2023). A novel RIPK1 inhibitor attenuates GVHD. Blood, 141 (9), 969-970. doi: 10.1182/blood.2022019019

A novel RIPK1 inhibitor attenuates GVHD

2023

Journal Article

Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity

Larson, Jemma H., Jin, Sujeong, Loschi, Michael, Wagers, Sara Bolivar, Thangavelu, Govindarajan, Zaiken, Michael C., McDonald-Hyman, Cameron, Saha, Asim, Aguilar, Ethan G., Koehn, Brent, Osborn, Mark J., Panoskaltsis-Mortari, Angela, Macdonald, Kelli P.A., Hill, Geoffrey R., Murphy, William J., Serody, Jonathan S, Maillard, Ivan, Kean, Leslie S., Kim, Sangwon V., Littman, Dan R. and Blazar, Bruce R. (2023). Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation, 23 (8), 1102-1115. doi: 10.1016/j.ajt.2023.01.030

Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity

2023

Conference Publication

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

Boiko, Julie R., Ensbey, Kathleen S., Schmidt, Christine R., Waltner, Olivia G., Minnie, Simone A., Furlan, Scott N. and Hill, Geoffrey R. (2023). Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00389-5

Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease

2023

Conference Publication

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

Geramita, Emily, Ventura, Kedwin, Bhise, Shruti, Moore, Erika, Krakow, Elizabeth F., Hill, Geoffrey R., Furlan, Scott N., Shlomchik, Warren D. and Ito, Sawa (2023). Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation. 2023 Tandem Meetings of ASTCT and CIBMTR, Orlando, FL United States, 15-19 February 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/s2666-6367(23)00122-7

Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation

2023

Journal Article

Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche

Koyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Takahashi, Shuichiro, Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2023). Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche. Blood, 141 (3), 315-319. doi: 10.1182/blood.2022015808

Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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