Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

299 works between 1996 and 2025
All (299) Journal Article (263) Book Chapter (2) Conference Publication (33) Other Outputs (1)

41 - 60 of 299 works

2022

Conference Publication

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

Hill, Joshua A., Lee, Yeon Joo, Vande Vusse, Lisa K., Xie, Hu, Lisa Chung, E., Keane-Candib, Jacob, Waghmare, Alpana, Cheng, Guang-Shing, Zhu, Haiying, Huang, Meei-Li, Hill, Geoffrey, Jerome, Keith R., Gharib, Sina A, Leisenring, Wendy M., Zerr, Danielle M., Dadwal, Sanjeet S. and Boeckh, Michael J. (2022). A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients. IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.1716

A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients

2022

Conference Publication

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

Zamora, Danniel, Krantz, Elizabeth M., Joncas-Schronce, Laurel, Akoto, Brenda, Stevens-Ayers, Terry L., Bender Ignacio, Rachel A., Hill, Joshua A., Degli-Esposti, Mariapia, Hill, Geoffrey and Boeckh, Michael J. (2022). Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT). IDWeek 2022, Washington, DC United States, 19-23 October 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofac492.549

Characterizing the Association of Pre-Existing Cytomegalovirus (CMV)-specific Humoral Immunity with CMV Reactivation Risk after Hematopoietic Cell Transplantation (HCT)

2022

Conference Publication

Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche

Koyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2022). Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-162592

Lithium Attenuates Graft-Versus-Host Disease Via Effects on the Intestinal Stem Cell Niche

2022

Journal Article

Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity

Minnie, Simone A., Waltner, Olivia G., Ensbey, Kathleen S., Nemychenkov, Nicole S., Schmidt, Christine R., Bhise, Shruti S., Legg, Samuel R. W., Campoy, Gabriela, Samson, Luke D., Kuns, Rachel D., Zhou, Ting, Huck, John D., Vuckovic, Slavica, Zamora, Danniel, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate A., Lane, Steven W., Boeckh, Michael, Ring, Aaron M., Furlan, Scott N. and Hill, Geoffrey R. (2022). Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. Science Immunology, 7 (76) eabo3420, 1-18. doi: 10.1126/sciimmunol.abo3420

Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity

2022

Journal Article

Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes

Browne, Daniel J., Liang, Fang, Gartlan, Kate H., Harris, Patrick N. A., Hill, Geoffrey R., Corrie, Simon R. and Markey, Kate A. (2022). Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes. Laboratory Medicine, 53 (5), 459-464. doi: 10.1093/labmed/lmac023

Multiplex microsphere PCR (mmPCR) allows simultaneous gram typing, detection of fungal DNA, and antibiotic resistance genes

2022

Journal Article

IFN-λ diminishes the severity of viral bronchiolitis in neonatal mice by limiting NADPH oxidase–induced PAD4-independent NETosis

Sebina, Ismail, Rashid, Ridwan B., Sikder, Md. Al Amin, Rahman, Muhammed Mahfuzur, Ahmed, Tufael, Radford-Smith, Daniel E., Kotenko, Sergei V., Hill, Geoffrey R., Bald, Tobias and Phipps, Simon (2022). IFN-λ diminishes the severity of viral bronchiolitis in neonatal mice by limiting NADPH oxidase–induced PAD4-independent NETosis. The Journal of Immunology, 208 (12), 2806-2816. doi: 10.4049/jimmunol.2100876

IFN-λ diminishes the severity of viral bronchiolitis in neonatal mice by limiting NADPH oxidase–induced PAD4-independent NETosis

2022

Journal Article

Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors

Gartlan, Kate H., Jaiswal, Jagdish K., Bull, Matthew R., Akhlaghi, Hedieh, Sutton, Vivien R., Alexander, Kylie A., Chang, Karshing, Hill, Geoffrey R., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Trapani, Joseph A., Charman, Susan A., Spicer, Julie A. and Jamieson, Stephen M. F. (2022). Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors. ACS Pharmacology and Translational Science, 5 (6), 429-439. doi: 10.1021/acsptsci.2c00009

Preclinical activity and pharmacokinetic/pharmacodynamic relationship for a series of novel benzenesulfonamide perforin inhibitors

2022

Journal Article

Retinoic acid signaling acts as a rheostat to balance Treg function

Thangavelu, Govindarajan, Andrejeva, Gabriela, Bolivar-Wagers, Sara, Jin, Sujeong, Zaiken, Michael C., Loschi, Michael, Aguilar, Ethan G., Furlan, Scott N., Brown, Chrysothemis C., Lee, Yu-Chi, Hyman, Cameron McDonald, Feser, Colby J., Panoskaltsis-Mortari, Angela, Hippen, Keli L., MacDonald, Kelli P., Murphy, William J., Maillard, Ivan, Hill, Geoffrey R., Munn, David H., Zeiser, Robert, Kean, Leslie S., Rathmell, Jeffrey C., Chi, Hongbo, Noelle, Randolph J. and Blazar, Bruce R. (2022). Retinoic acid signaling acts as a rheostat to balance Treg function. Cellular and Molecular Immunology, 19 (7), 820-833. doi: 10.1038/s41423-022-00869-y

Retinoic acid signaling acts as a rheostat to balance Treg function

2022

Journal Article

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Zaiken, Michael C., Flynn, Ryan, Paz, Katelyn G., Rhee, Stephanie Y., Jin, Sujeong, Mohamed, Fathima A., Saha, Asim, Thangavelu, Govindarajan, Park, Paul M.C., Hemming, Matthew L., Sage, Peter T., Sharpe, Arlene H., DuPage, Michel, Bluestone, Jeffrey A., Panoskaltsis-Mortari, Angela, Cutler, Corey S., Koreth, John, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Luznik, Leo, Maillard, Ivan, Hill, Geoffrey R., MacDonald, Kelli P.A., Munn, David H., Serody, Jonathan S., Murphy, William J., Kean, Leslie S., Zhang, Yi ... Blazar, Bruce R. (2022). BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes. Blood, 139 (19), 2983-2997. doi: 10.1182/blood.2021014557

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

2022

Journal Article

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele WL., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra and MacDonald, Kelli PA. (2022). ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. JHEP Reports, 4 (1) 100386, 1-14. doi: 10.1016/j.jhepr.2021.100386

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

2021

Journal Article

CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant

Yeh, Albert C., Varelias, Antiopi, Reddy, Anupama, Barone, Sierra M., Olver, Stuart D., Chilson, Kate, Onstad, Lynn E., Ensbey, Kathleen S., Henden, Andrea S, Samson, Luke, Jaeger, Carla A, Bi, Timothy, Dahlman, Kimberly B., Kim, Tae Kon, Zhang, Ping, Degli-Esposti, Mariapia A., Newell, Evan W., Jagasia, Madan H., Irish, Jonathan M., Lee, Stephanie J. and Hill, Geoffrey R. (2021). CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant. Blood, 138 (26), 2874-2885. doi: 10.1182/blood.2020009492

CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant

2021

Journal Article

Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT

Inoue, Takayuki, Koyama, Motoko, Kaida, Katsuji, Ikegame, Kazuhiro, Ensbey, Kathleen S., Samson, Luke, Takahashi, Shuichiro, Zhang, Ping, Minnie, Simone A., Maruyama, Satoshi, Ishii, Shinichi, Daimon, Takashi, Fukuda, Takahiro, Nakamae, Hirohisa, Ara, Takahide, Maruyama, Yumiko, Ishiyama, Ken, Ichinohe, Tatsuo, Atsuta, Yoshiko, Blazar, Bruce R., Furlan, Scott N., Ogawa, Hiroyasu and Hill, Geoffrey R. (2021). Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT. JCI Insight, 6 (22) e153551. doi: 10.1172/jci.insight.153551

Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT

2021

Journal Article

Early Cytomegalovirus Reactivation after Allogenic Bone Marrow Transplantation Is Associated with the Loss of Recipient-Derived Humoral Immunity and Is Reduced By IL-6 Inhibition

Zhang, Ping, Fleming, Peter, Andoniou, Christopher, Martins, Jose Paulo, Saldan, Alda, Kuns, Rachel, McEnroe, Benjamin, Henden, Andrea S, Olver, Stuart, Ekwe, Adaeze, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R, Ensbey, Kathleen S, Boeckh, Michael, Kennedy, Glen A, Degli-Esposti, Mariapia, Hill, Geoff R. and Tey, Siok-Keen (2021). Early Cytomegalovirus Reactivation after Allogenic Bone Marrow Transplantation Is Associated with the Loss of Recipient-Derived Humoral Immunity and Is Reduced By IL-6 Inhibition. Blood, 138 (Supplement 1), 138. doi: 10.1182/blood-2021-146643

Early Cytomegalovirus Reactivation after Allogenic Bone Marrow Transplantation Is Associated with the Loss of Recipient-Derived Humoral Immunity and Is Reduced By IL-6 Inhibition

2021

Journal Article

Mouse models of antigen presentation in hematopoietic stem cell transplantation

Koyama, Motoko and Hill, Geoffrey R. (2021). Mouse models of antigen presentation in hematopoietic stem cell transplantation. Frontiers in Immunology, 12 715893. doi: 10.3389/fimmu.2021.715893

Mouse models of antigen presentation in hematopoietic stem cell transplantation

2021

Journal Article

The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models

Teshima, Takanori and Hill, Geoffrey R. (2021). The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models. Frontiers in Immunology, 12 715424. doi: 10.3389/fimmu.2021.715424

The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models

2021

Journal Article

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

Henden, Andrea S., Koyama, Motoko, Robb, Renee J., Forero, Adriana, Kuns, Rachel D., Chang, Karshing, Ensbey, Kathleen S., Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nicole, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey R. (2021). IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood, 138 (8), 722-737. doi: 10.1182/blood.2020006375

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

2021

Journal Article

Current Concepts and Advances in Graft-Versus-Host Disease Immunology

Hill, Geoffrey R., Betts, Brian C., Tkachev, Victor, Kean, Leslie S. and Blazar, Bruce R. (2021). Current Concepts and Advances in Graft-Versus-Host Disease Immunology. Annual Review of Immunology, 39 (1), 19-49. doi: 10.1146/annurev-immunol-102119-073227

Current Concepts and Advances in Graft-Versus-Host Disease Immunology

2021

Journal Article

Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?

Minnie, Simone A. and Hill, Geoffrey R. (2021). Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?. Frontiers in Immunology, 12 651288. doi: 10.3389/fimmu.2021.651288

Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?

2021

Conference Publication

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

Henden, Andrea S., Robb, Renee, Forero, Adriana, Kuns, Rachel D., Ensbey, Kathleen S., Chang, Karshing, Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nic, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey (2021). Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd. 2021 TCT Meetings of ASTCT and CIBMTR, Online, 8-12 February 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2666-6367(21)00107-x

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

2021

Journal Article

Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach

Ueda Oshima, Masumi, Sandmaier, Brenda M., Petersdorf, Effie, Flowers, Mary E., Hill, Geoffrey R., Lee, Stephanie J., Appelbaum, Frederick R., Carpenter, Paul A., Baker, K. Scott, Connelly-Smith, Laura, McCool, Andrea, Elgar, Suni, Pergam, Steven A., Liu, Catherine, Stewart, F. Marc and Mielcarek, Marco (2021). Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach. Bone Marrow Transplantation, 56 (2), 305-313. doi: 10.1038/s41409-020-01068-x

Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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