Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

278 works between 1996 and 2024
All (278) Journal Article (250) Book Chapter (2) Conference Publication (26)

101 - 120 of 278 works

2018

Journal Article

Atypical chemokine receptor 4 shapes activated B cell fate

Kara, Ervin E., Bastow, Cameron R., McKenzie, Duncan R., Gregor, Carly E., Fenix, Kevin A., Babb, Rachelle, Norton, Todd S., Zotos, Dimitra, Rodda, Lauren B., Hermes, Jana R., Bourne, Katherine, Gilchrist, Derek S., Nibbs, Robert J., Alsharifi, Mohammed, Vinuesa, Carola G., Tarlinton, David M., Brink, Robert, Hill, Geoffrey R., Cyster, Jason G., Comerford, Iain and McColl, Shaun R. (2018). Atypical chemokine receptor 4 shapes activated B cell fate. Journal of Experimental Medicine, 215 (3), 801-813. doi: 10.1084/jem.20171067

Atypical chemokine receptor 4 shapes activated B cell fate

2018

Journal Article

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

Prestipino, Alessandro, Emhardt, Alica J., Aumann, Konrad, O'Sullivan, David, Gorantla, Sivahari P., Duquesne, Sandra, Melchinger, Wolfgang, Braun, Lukas, Vuckovic, Slavica, Boerries, Melanie, Busch, Hauke, Halbach, Sebastian, Pennisi, Sandra, Poggio, Teresa, Apostolova, Petya, Veratti, Pia, Hettich, Michael, Niedermann, Gabriele, Bartholomä, Mark, Shoumariyeh, Khalid, Jutzi, Jonas S., Wehrle, Julius, Dierks, Christine, Becker, Heiko, Schmitt-Graeff, Annette, Follo, Marie, Pfeifer, Dietmar, Rohr, Jan, Fuchs, Sebastian ... Zeiser, Robert (2018). Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science Translational Medicine, 10 (429) eaam7729, eaam7729. doi: 10.1126/scitranslmed.aam7729

Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

2018

Journal Article

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

James, Kylie R., Soon, Megan S. F., Sebina, Ismail, Fernandez-Ruiz, Daniel, Davey, Gayle, Liligeto, Urijah N., Nair, Arya Sheela, Fogg, Lily G., Edwards, Chelsea L., Best, Shannon E., Lansink, Lianne I. M., Schroder, Kate, Wilson, Jane A. C., Austin, Rebecca, Suhrbier, Andreas, Lane, Steven W., Hill, Geoffrey R., Engwerda, Christian R., Heath, William R. and Haque, Ashraful (2018). IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection. Journal of Immunology, 200 (4), 1443-1456. doi: 10.4049/jimmunol.1700782

IFN regulatory factor 3 balances Th1 and T follicular helper immunity during nonlethal blood-stage Plasmodium infection

2018

Journal Article

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

Markey, Kate A., Kuns, Rachel D., Browne, Daniel J., Gartlan, Kate H., Robb, Renee J., Martins, J. Paulo, Henden, Andrea S., Minnie, Simone A., Cheong, Melody, Koyama, Motoko, Smyth, Mark J., Steptoe, Raymond J., Belz, Gabrielle, Brocker, Thomas, Degli-Esposti, Mariapia A., Lane, Steven W. and Hill, Geoffrey R. (2018). Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD. Clinical Cancer Research, 24 (7), 1604-1616. doi: 10.1158/1078-0432.CCR-17-2148

Flt-3L expansion of recipient CD8α+ dendritic cells deletes alloreactive donor T cells and represents an alternative to post-transplant cyclophosphamide for the prevention of GVHD

2018

Journal Article

Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples

Liang, Fang, Browne, Daniel J., Gray, Megan J., Gartlan, Kate H., Smith, David D., Barnard, Ross T., Hill, Geoffrey R., Corrie, Simon R. and Markey, Kate A. (2018). Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples. ACS Infectious Diseases, 4 (5), 837-844. doi: 10.1021/acsinfecdis.7b00277

Development of a Multiplexed Microsphere PCR for Culture-Free Detection and Gram-Typing of Bacteria in Human Blood Samples

2017

Journal Article

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

Lynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 (2), 537-557. doi: 10.1084/jem.20170298

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

2017

Journal Article

Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience

Mediwake, Heshani, Curley, Cameron, Butler, Jason, McLean, Angela, Tey, Siok, Hill, Geoffrey R., Morton, Anthony, Misra, Ashish, Subramoniapillai, Elango, Durrant, Simon and Kennedy, Glen A. (2017). Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience. Blood Cancer Journal, 7 (12) 55, 1-4. doi: 10.1038/s41408-017-0012-0

Mismatched unrelated donor allogeneic stem cell transplant for high risk haematological malignancy: A single centre experience

2017

Journal Article

Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis

Mittal, Deepak, Vijayan, Dipti, Putz, Eva M., Aguilera, Amelia R., Markey, Kate A., Straube, Jasmin, Kazakoff, Stephen, Nutt, Stephen L., Takeda, Kazuyoshi, Hill, Geoffrey R., Waddell, Nicola and Smyth, Mark J. (2017). Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis. Cancer Immunology Research, 5 (12), 1098-1108. doi: 10.1158/2326-6066.CIR-17-0341

Interleukin-12 from CD103+ Batf3-dependent dendritic cells required for NK-cell suppression of metastasis

2017

Journal Article

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

Gartlan, Kate H., Bommiasamy, Hemamalini, Paz, Katelyn, Wilkinson, Andrew N., Owen, Mary, Reichenbach, Dawn K., Banovic, Tatjana, Wehner, Kimberly, Buchanan, Faith, Varelias, Antiopi, Kuns, Rachel D., Chang, Karshing, Fedoriw, Yuri, Shea, Thomas, Coghill, James, Zaiken, Michael, Plank, Maximilian W., Foster, Paul S., Clouston, Andrew D., Blazar, Bruce R., Serody, Jonathan S. and Hill, Geoffrey R. (2017). A critical role for donor-derived IL-22 in cutaneous chronic GVHD. American Journal of Transplantation , 18 (4), 810-820. doi: 10.1111/ajt.14513

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

2017

Journal Article

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

Sebina, I., Fogg, L. G., James, K. R., Soon, M. S. F., Akter, J., Thomas, B. S., Hill, G. R., Engwerda, C. R. and Haque, A. (2017). IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection. Parasite Immunology, 39 (10) e12455, e12455. doi: 10.1111/pim.12455

IL-6 promotes CD4(+) T-cell and B-cell activation during Plasmodium infection

2017

Journal Article

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

Porter, Amy H., Leveque-El Mouttie, Lucie, Vu, Therese, Bruedigam, Claudia, Sutton, Joanne, Jacquelin, Sebastien, Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2017). Acute myeloid leukemia stem cell function is preserved in the absence of autophagy. Haematologica, 102 (9), E344-E347. doi: 10.3324/haematol.2017.166389

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

2017

Journal Article

Cytokine mediators of chronic graft-versus-host disease

MacDonald, Kelli P. A., Blazar, Bruce R. and Hill, Geoffrey R. (2017). Cytokine mediators of chronic graft-versus-host disease. Journal of Clinical Investigation, 127 (7), 2452-2463. doi: 10.1172/JCI90593

Cytokine mediators of chronic graft-versus-host disease

2017

Journal Article

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

AL-Kouba, Jane, Wilkinson, Andrew N., Starkey, Malcolm R., Rudraraju, Rajeev, Werder, Rhiannon B., Liu, Xiao, Law, Soi-Cheng, Horvat, Jay C., Brooks, Jeremy F., Hill, Geoffrey R., Davies, Janet M., Phipps, Simon, Hansbro, Philip M. and Steptoe, Raymond J. (2017). Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation. JCI Insight, 2 (11) e85742. doi: 10.1172/jci.insight.85742

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

2017

Journal Article

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

Forcade, Edouard, Paz, Katelyn, Flynn, Ryan, Griesenauer, Brad, Amet, Tohti, Li, Wei, Liu, Liangyi, Bakoyannis, Giorgos, Jiang, Di, Chu, Hong Wei, Lobera, Mercedes, Yang, Jianfei, Wilkes, David S., Du, Jing, Gartlan, Kate, Hill, Geoffrey R., MacDonald, Kelli P. A., Espada, Eduardo L., Blanco, Patrick, Serody, Jonathan S., Koreth, John, Cutler, Corey S., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Paczesny, Sophie and Blazar, Bruce R. (2017). An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition. JCI Insight, 2 (12) e92111. doi: 10.1172/jci.insight.92111

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

2017

Journal Article

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production

Du, Jing, Paz, Katelyn, Flynn, Ryan, Vulic, Ante, Robinson, Tara M., Lineburg, Katie E., Alexander, Kylie A., Meng, Jingjing, Roy, Sabita, Panoskaltsis-Mortari, Angela, Loschi, Michael, Hill, Geoffrey R., Serody, Jonathan S., Maillard, Ivan, Miklos, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, MacDonald, Kelli P., Schacker, Timothy W., Luznik, Leo and Blazar, Bruce R. (2017). Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production. Blood, 129 (18), 2570-2580. doi: 10.1182/blood-2017-01-758854

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production

2017

Conference Publication

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P.A., Hugenholtz, Philip and Hill, Geoff R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Immunology 2017™ Meeting, Washington, DC United States, 12-16 May 2017. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.198.supp.82.8

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

2017

Journal Article

Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?

Snowden, John A. and Hill, Geoffrey R. (2017). Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?. British Journal of Haematology, 177 (3), 341-342. doi: 10.1111/bjh.14565

Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?

2017

Journal Article

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

2017

Journal Article

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, Slavica, Vandyke, Kate, Rickards, David A., Mccauley Winter, Padraig, Brown, Simon H. J., Mitchell, Todd W., Liu, Jun, Lu, Jun, Askenase, Philip W., Yuriev, Elizabeth, Capuano, Ben, Ramsland, Paul A., Hill, Geoffrey R., Zannettino, Andrew C. W. and Hutchinson, Andrew T. (2017). The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells. British Journal of Haematology, 177 (3), 423-440. doi: 10.1111/bjh.14561

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

2017

Journal Article

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

Gartlan, Kate H., Varelias, Antiopi, Koyama, Motoko, Robb, Renee J., Markey, Kate A., Chang, Karshing, Wilkinson, Andrew N., Smith, David, Ullah, Md Ashik, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Teal, Bianca E., Cheong, Melody, Teng, Michele W. L., Smyth, Mark J., Tey, Siok-Keen, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2017). Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT. Blood Advances, 1 (6), 341-351. doi: 10.1182/bloodadvances.2016002980

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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