Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

278 works between 1996 and 2024
All (278) Journal Article (250) Book Chapter (2) Conference Publication (26)

121 - 140 of 278 works

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2017

Journal Article

Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance

Hill, Geoffrey R. (2017). Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance. Transplantation, 101 (2), 232-233. doi: 10.1097/TP.0000000000001550

Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance

2017

Journal Article

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A ., Hugenholtz, Philip and Hill, Geoffrey R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood, 129 (15), 2172-2185. doi: 10.1182/blood-2016-08-732628

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

2017

Journal Article

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

MacDonald, Kelli P. A., Hill, Geoffrey R. and Blazar, Bruce R. (2017). Chronic graft-versus-host disease: biological insights from preclinical and clinical studies. Blood, 129 (1), 13-21. doi: 10.1182/blood-2016-06-686618

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

2016

Journal Article

Novel platform technology for modular mucosal vaccine that protects against streptococcus

Zaman, Mehfuz, Ozberk, Victoria, Langshaw, Emma L., McPhun, Virginia, Powell, Jessica L., Phillips, Zachary N., Ho, Mei Fong, Calcutt, Ainslie, Batzloff, Michael R., Toth, Istvan, Hill, Geoffrey R., Pandey, Manisha and Good, Michael F. (2016). Novel platform technology for modular mucosal vaccine that protects against streptococcus. Scientific Reports, 6 (1) 39274, 1-11. doi: 10.1038/srep39274

Novel platform technology for modular mucosal vaccine that protects against streptococcus

2016

Journal Article

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

Sebina, Ismail, James, Kylie R., Soon, Megan S. F., Fogg, Lily G., Best, Shannon E., Labastida Rivera, Fabian de, Montes de Oca, Marcela, Amante, Fiona H., Thomas, Bryce S., Beattie, Lynette, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J., Hertzog, Paul J., Hill, Geoffrey R., Hutloff, Andreas, Engwerda, Christian R. and Haque, Ashraful (2016). IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection. PLoS Pathogens, 12 (11) e1005999, e1005999. doi: 10.1371/journal.ppat.1005999

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

2016

Journal Article

Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor

Ngiow, Shin Foong, Young, Arabella, Blake, Stephen J., Hill, Geoffrey R., Yagita, Hideo, Teng, Michele W. L., Korman, Alan J. and Smyth, Mark J. (2016). Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor. Cancer Research, 76 (21), 6266-6277. doi: 10.1158/0008-5472.CAN-16-2141

Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor

2016

Journal Article

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

Le Texier, Laetitia, Lineburg, Katie E., Cao, Benjamin, McDonald-Hyman, Cameron, Leveque-El Mouttie, Lucie, Nicholls, Jemma, Melino, Michelle, Nalkurthi, Blessy C., Alexander, Kylie A., Teal, Bianca, Blake, Stephen J., Souza-Fonseca-Guimaraes, Fernando, Engwerda, Christian R., Kuns, Rachel D., Lane, Steven W., Teng, Michele, Teh, Charis, Gray, Daniel, Clouston, Andrew D., Nilsson, Susan K., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease. JCI Insight, 1 (15) e86850, e86850. doi: 10.1172/jci.insight.86850

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

2016

Journal Article

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Leveque-El Mouttie, Lucie, Koyama, Motoko, Le Texier, Laetitia, Markey, Kate A., Cheong, Melody, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Alexander, Kylie A., Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. Blood, 128 (6), 794-804. doi: 10.1182/blood-2015-11-680876

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

2016

Journal Article

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

McDonald-Hyman, Cameron, Flynn, Ryan, Panoskaltsis-Mortari, Angela, Peterson, Nicholas, MacDonald, Kelli P. A., Hill, Geoffrey R., Luznik, Leo, Serody, Jonathan S., Murphy, William J., Maillard, Ivan, Munn, David H., Turka, Laurence A., Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome and Blazar, Bruce R. (2016). Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner. Blood, 128 (7), 1013-1017. doi: 10.1182/blood-2016-05-715896

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

2016

Journal Article

Pharmacokinetics and immunological outcomes of alemtuzumab-based treatment for steroid-refractory acute GvHD

Tey, S-K., Vuckovic, S., Varelias, A., Martins, J. P., Olver, S., Samson, L., Sturgeon, E., Leach, J., Avery, J., Nakagaki, M., Butler, J. P., Curley, C., Morton, A. J., Durrant, S. T., Kennedy, G. A. and Hill, G. R. (2016). Pharmacokinetics and immunological outcomes of alemtuzumab-based treatment for steroid-refractory acute GvHD. Bone Marrow Transplantation, 51 (8), 1153-1155. doi: 10.1038/bmt.2016.83

Pharmacokinetics and immunological outcomes of alemtuzumab-based treatment for steroid-refractory acute GvHD

2016

Journal Article

Coinfection with human cytomegalovirus genetic variants in transplant recipients and its impact on antiviral T cell immune reconstitution

Smith, Corey, Brennan, Rebekah M., Tey, Siok-Keen, Smyth, Mark J., Burrows, Scott R., Miles, John J., Hill, Geoffrey R. and Khanna, Rajiv (2016). Coinfection with human cytomegalovirus genetic variants in transplant recipients and its impact on antiviral T cell immune reconstitution. Journal of Virology, 90 (16), 7497-7507. doi: 10.1128/JVI.00297-16

Coinfection with human cytomegalovirus genetic variants in transplant recipients and its impact on antiviral T cell immune reconstitution

2016

Journal Article

Alloantigen presentation and graft-versus-host disease: fuel for the fire

Koyama, Motoko and Hill, Geoffrey R. (2016). Alloantigen presentation and graft-versus-host disease: fuel for the fire. Blood, 127 (24), 2963-2970. doi: 10.1182/blood-2016-02-697250

Alloantigen presentation and graft-versus-host disease: fuel for the fire

2016

Conference Publication

Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance

MacDonald, Kelli P. A., Le Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie, Nicholls, Jemma, Guimaraes, Fernando Souza-Fonseca, Alexander, Kylie, Clouston, Andrew, Blazar, Bruce R. and Hill, Geoff R. (2016). Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance. Immunology 2016 Meeting, Seattle, WA United States, 13-17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.125.14

Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance

2016

Journal Article

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Flynn, Ryan, Paz, Katelyn, Du, Jing, Reichenbach, Dawn K., Taylor, Patricia A., Panoskaltsis-Mortari, Angela, Vulic, Ante, Luznik, Leo, MacDonald, Kelli K. P., Hill, Geoffrey R., Nyuydzefe, Melanie S., Weiss, Jonathan M., Chen, Wei, Trzeciak, Alissa, Serody, Jon S., Aguilar, Ethan G., Murphy, William J., Maillard, Ivan, Munn, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, Waksal, Samuel D., Zanin-Zhorov, Alexandra and Blazar, Bruce R. (2016). Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood, 127 (17), 2144-2154. doi: 10.1182/blood-2015-10-678706

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

2016

Journal Article

Functional reconstitution of natural killer cells in allogeneic hematopoietic stem cell transplantation

Ullah, Md Ashik, Hill, Geoffrey R. and Tey, Siok-Keen (2016). Functional reconstitution of natural killer cells in allogeneic hematopoietic stem cell transplantation. Frontiers in Immunology, 7 (APR) 144, 144. doi: 10.3389/fimmu.2016.00144

Functional reconstitution of natural killer cells in allogeneic hematopoietic stem cell transplantation

2016

Journal Article

Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies

Guillerey, Camille, Nakamura, Kyohei, Vuckovic, Slavica, Hill, Geoffrey R. and Smyth, Mark J. (2016). Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies. Cellular and Molecular Life Sciences, 73 (8), 1569-1589. doi: 10.1007/s00018-016-2135-z

Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies

2016

Journal Article

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

Vu, Therese, Austin, Rebecca, Kuhn, Catherine Paine, Bruedigam, Claudia, Song, Axia, Guignes, Solene, Jacquelin, Sebastien, Ramshaw, Hayley S., Hill, Geoffrey R., Lopez, Angel F. and Lane, Steven W. (2016). Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling. Haematologica, 101 (3), E77-E80. doi: 10.3324/haematol.2015.136705

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signalling

2016

Journal Article

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

2016

Journal Article

Erratum: Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated Tissue pathology (PLoS Pathogens (2016) 12:1 (e1005398) DOI: 10.1371/journal.ppat.1005398)

De Oca, Marcela Montes, Kumar, Rajiv, De Labastida Rivera, Fabian, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, Shannon E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Muller, Werner, Cretney, Erika, Nutt, Stephen L., Smyth, Mark J., Haque, Ashraful, Hill, Geoffrey R., Sundar, Shyam, Kallies, Axel and Engwerda, Christian R. (2016). Erratum: Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated Tissue pathology (PLoS Pathogens (2016) 12:1 (e1005398) DOI: 10.1371/journal.ppat.1005398). PLoS Pathogens, 12 (2) e1005460. doi: 10.1371/journal.ppat.1005460

Erratum: Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated Tissue pathology (PLoS Pathogens (2016) 12:1 (e1005398) DOI: 10.1371/journal.ppat.1005398)

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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