Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

278 works between 1996 and 2024
All (278) Journal Article (250) Book Chapter (2) Conference Publication (26)

141 - 160 of 278 works

2016

Journal Article

Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated tissue pathology

Montes de Oca, Marcela, Kumar, Rajiv, de Labastida Rivera, Fabian, Amante, Fiona H., Sheel, Meru, Faleiro, Rebecca J., Bunn, Patrick T., Best, S.E., Beattie, Lynette, Ng, Susanna S., Edwards, Chelsea L., Muller, Werner, Cretney, Erika, Nutt, Stephen L., Smyth, Mark J., Haque, Ashraful, Hill, Geoffrey R., Sundar, Shyam, Kallies, Axel and Engwerda, Christian R. (2016). Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated tissue pathology. PLoS Pathogens, 12 (1) e1005398, 1-21. doi: 10.1371/journal.ppat.1005398

Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated tissue pathology

2015

Journal Article

IL-17A-Producing gamma delta T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver

Sheel, Meru, Beattie, Lynette, Frame, Teija C. M., Rivera, Fabian de Labastida, Faleiro, Rebecca J., Bunn, Patrick T., de Oca, Marcela Montes, Edwards, Chelsea L., Ng, Susanna S., Kumar, Rajiv, Amante, Fiona H., Best, Shannon E., McColl, Shaun R., Varelias, Antiopi, Kuns, Rachel D., MacDonald, Kelli P. A., Smyth, Mark J., Haque, Ashraful, Hill, Geoff R. and Engwerda, Christian R. (2015). IL-17A-Producing gamma delta T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver. Journal of Immunology, 195 (12), 5707-5717. doi: 10.4049/jimmunol.1501046

IL-17A-Producing gamma delta T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver

2015

Journal Article

CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells

Kara, Ervin E., McKenzie, Duncan R., Bastow, Cameron R., Gregor, Carly E., Fenix, Kevin A., Ogunniyi, Abiodim D., Paton, James C., Mack, Matthias, Pombal, Diana R., Seillet, Cyrill, Dubois, Benedocte, Liston, Adrian, Macdonald, Kelli P. A., Belz, Gabrielle T., Smyth, Mark J., Hill, Geoffrey R., Comerford, Iain and McColl, Shaun R. (2015). CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nature Communications, 6 (1) 8644, 8644. doi: 10.1038/ncomms9644

CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells

2015

Journal Article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

Gartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

2015

Journal Article

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

Wikstrom, Matthew E., Fleming, Peter, Kuns, Rachel D., Schuster, Iona S., Voigt, Valentina, Miller, Gregory, Clouston, Andrew D., Tey, Siok-Keen, Andoniou, Christopher E., Hill, Geoffrey R. and Degli-Esposti, Mariapia A. (2015). Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice. Blood, 126 (12), 1503-1514. doi: 10.1182/blood-2015-01-622837

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

2015

Journal Article

Imaging the immunological synapse between dendritic cells and T cells

Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Imaging the immunological synapse between dendritic cells and T cells. Journal of Immunological Methods, 423, 40-44. doi: 10.1016/j.jim.2015.04.029

Imaging the immunological synapse between dendritic cells and T cells

2015

Journal Article

Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease

Koyama, Motoko, Cheong, Melody, Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Locke, Kelly R., Lineburg, Katie E., Teal, Bianca E., Leveque-El Mouttie, Lucie, Bunting, Mark D., Vuckovic, Slavica, Zhang, Ping, Teng, Michele W. L., Varelias, Antiopi, Tey, Siok-Keen, Wockner, Leesa F., Engwerda, Christian R., Smyth, Mark J., Belz, Gabrielle T., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease. Journal of Experimental Medicine, 212 (8), 1303-1321. doi: 10.1084/jem.20150329

Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease

2015

Journal Article

Erratum: Immunosurveillance and therapy of multiple myeloma are CD226 dependent

Guillerey, Camille, de Andrade, Lucas Ferrari, Vuckovic, Slavica, Miles, Kim, Ngiow, Shin Foong, Yong, Michelle C. R., Teng, Michele W. L., Colonna, Marco, Ritchie, David S., Chesi, Marta, Bergsagel, P. Leif, Hill, Geoffrey R., Smyth, Mark J. and Martinet, Ludovic (2015). Erratum: Immunosurveillance and therapy of multiple myeloma are CD226 dependent. Journal of Clinical Investigation, 125 (7), 2904-2904. doi: 10.1172/JCI82646

Erratum: Immunosurveillance and therapy of multiple myeloma are CD226 dependent

2015

Journal Article

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

Flynn, Ryan, Allen, Jessica L., Luznik, Leo, MacDonald, Kelli P., Paz, Katelyn, Alexander, Kylie A., Vulic, Ante, Du, Jing, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Poe, Jonathan C., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Maillard, Ivan, Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Chao, Nelson J., Clynes, Raphael A., Sarantopoulos, Stefanie and Blazar, Bruce R. (2015). Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood, 125 (26), 4085-4094. doi: 10.1182/blood-2014-08-595470

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

2015

Journal Article

Cytokines in graft-versus-host disease

Henden, Andrea S. and Hill, Geoffrey R. (2015). Cytokines in graft-versus-host disease. Journal of Immunology, 194 (10), 4604-4612. doi: 10.4049/jimmunol.1500117

Cytokines in graft-versus-host disease

2015

Journal Article

Autophagy is required for stem cell mobilization by G-CSF

Leveque-El Mouttie, Lucie, Vu, Therese, Lineburg, Katie E., Kuns, Rachel D., Bagger, Frederik O., Teal, Bianca E., Lor, Mary, Boyle, Glen M., Bruedigam, Claudia, Mintern, Justine D., Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2015). Autophagy is required for stem cell mobilization by G-CSF. Blood, 125 (19), 2933-2936. doi: 10.1182/blood-2014-03-562660

Autophagy is required for stem cell mobilization by G-CSF

2015

Journal Article

NK cells require IL-28R for optimal in vivo activity

Souza-Fonseca-Guimaraes, Fernando, Young, Arabella, Mittal, Deepak, Martinet, Ludovic, Bruedigam, Claudia, Takeda, Kazuyoshi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Hill, Geoffrey R. and Smyth, Mark J. (2015). NK cells require IL-28R for optimal in vivo activity. Proceedings of the National Academy of Sciences of the United States of America, 112 (18), E2376-E2384. doi: 10.1073/pnas.1424241112

NK cells require IL-28R for optimal in vivo activity

2015

Journal Article

Immunosurveillance and therapy of multiple myeloma are CD226 dependent

Guillerey, Camille, de Andrade, Lucas Ferrari, Vuckovic, Slavica, Miles, Kim, Ngiow, Shin Foong, Yong, Michelle C. R., Teng, Michele W. L., Colonna, Marco, Ritchie, David S., Chesi, Martha, Bergsagel, P. Leif, Hill, Geoffrey R., Smyth, Mark J. and Martinet, Ludovic (2015). Immunosurveillance and therapy of multiple myeloma are CD226 dependent. Journal of Clinical Investigation, 125 (5), 2077-2089. doi: 10.1172/JCI77181

Immunosurveillance and therapy of multiple myeloma are CD226 dependent

2015

Journal Article

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

Varelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2015). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood, 125 (15), 2435-2444. doi: 10.1182/blood-2014-07-590232

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

2015

Journal Article

CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells

Paget, C., Chow, M. T., Gherardin, N. A., Beavis, P. A., Uldrich, A. P., Duret, H., Hassane, M., Souza-Fonseca-Guimaraes, F., Mogilenko, D. A., Staumont-Salle, D., Escalante, N. K., Hill, G. R., Neeson, P., Ritchie, D. S., Dombrowicz, D., Mallevaey, T., Trottein, F., Belz, G. T., Godfrey, D. I. and Smyth, M. J. (2015). CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells. Immunology and Cell Biology, 93 (2), 198-212. doi: 10.1038/icb.2014.94

CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells

2015

Journal Article

Autophagy and haematopoietic stem cell transplantation

Leveque, Lucie, Le Texier, Laetitia, Lineburg, Katie E., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2015). Autophagy and haematopoietic stem cell transplantation. Immunology and Cell Biology, 93 (1), 43-50. doi: 10.1038/icb.2014.95

Autophagy and haematopoietic stem cell transplantation

2015

Journal Article

Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation

Ullah, Md Ashik, Revez, Joana A., Loh, Zhixuan, Simpson, Jennifer, Zhang, Vivian, Bain, Lisa, Varelias, Antiopi, Rose-John, Stefan, Blumenthal, Antje, Smyth, Mark J., Hill, Geoffrey R., Sukkar, Manuel A. R, Ferreira M. A. R. and Phipps, Simon (2015). Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation. Journal of Allergy and Clinical Immunology, 136 (4), 1065-1073. doi: 10.1016/j.jaci.2015.02.032

Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation

2015

Journal Article

Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation

Tey, S.-K., Davenport, M. P., Hill, G. R., Kennedy, G. A., Durrant, S. T., Khanna, R. and Cromer, D. (2015). Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation. Bone Marrow Transplantation, 50 (2), 315-316. doi: 10.1038/bmt.2014.265

Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation

2015

Journal Article

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Uryu, Hidetaka, Hashimoto, Daigo, Kato, Koji, Hayase, Eiko, Matsuoka, Satomi, Ogasawara, Reiki, Takahashi, Shuichiro, Maeda, Yoshinobu, Iwasaki, Hiromi, Miyamoto, Toshihiro, Saijo, Shinobu, Iwakura, Yoichiro, Hill, Geoffrey R., Akashi, Koichi and Teshima, Takanori (2015). α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice. Blood, 125 (19), 3014-3023. doi: 10.1182/blood-2014-12-615781

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

2014

Journal Article

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

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