
Overview
Background
Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au
NHMRC Australia and QLD Health Senior Clinical Research Fellow
Coordinator, Cancer Programme, QIMR Berghofer
Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer
Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital
Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital
Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.
Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.
Availability
- Honorary Professor Geoffrey Hill is:
- Available for supervision
Fields of research
Qualifications
- Bachelor, The University of Auckland
- Masters (Coursework) of Medicine Surgery, The University of Auckland
- Doctoral Diploma of Medicine, The University of Auckland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
Works
Search Professor Geoffrey Hill’s works on UQ eSpace
2013
Journal Article
Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera
Mullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013). Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 (18), 3692-3702. doi: 10.1182/blood-2012-05-432989
2013
Journal Article
Promoting regulation via the inhibition of DNAM-1 after transplantation
Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., Smyth, Mark J., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2013). Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood, 121 (17), 3511-3520. doi: 10.1182/blood-2012-07-444026
2013
Journal Article
CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3
Seillet, Cyril, Jackson, Jacob T., Markey, Kate A., Brady, Hugh J. M., Hill, Geoffrey R., MacDonald, Kelli P. A., Nutt, Stephen L. and Belz, Gabrielle T. (2013). CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3. Blood, 121 (9), 1574-1583. doi: 10.1182/blood-2012-07-445650
2013
Journal Article
Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy
Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100
2013
Book Chapter
Cytokines in Graft-versus-host Disease and Graft-versus-leukemia
Markey, K.A., MacDonald, K.P.A. and Hill, G.R. (2013). Cytokines in Graft-versus-host Disease and Graft-versus-leukemia. Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation. (pp. 357-391) New York, NY, U.S.A.: Elsevier Inc.. doi: 10.1016/B978-0-12-416004-0.00016-1
2013
Journal Article
Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection
Zinkernagel, M.S., Chinnery, H.R., Ong, M.L., Petitjean, C., Voigt, V., McLenachan, S., McMenamin, P.G., Hill, G.R., Forrester, J.V., Wikstrom, M.E. and Degli-Esposti, M.A. (2013). Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection. American Journal of Pathology, 182 (3), 875-885. doi: 10.1016/j.ajpath.2012.11.031
2012
Journal Article
Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation
Robb, R.J., Lineburg, K.E., Kuns, R.D., Wilson, Y.A., Raffelt, N.C., Olver, S.D., Varelias, A., Alexander, K.A., Teal, B.E., Sparwasser, T., Hammerling, G.J., Markey, K.A., Koyama, M., Clouston, A.D., Engwerda, C.R., Hill, G.R. and MacDonald, K.P.A. (2012). Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation. Blood, 119 (24), 5898-5908. doi: 10.1182/blood-2011-12-396119
2012
Journal Article
Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets
Markey, Kate A., Koyama, Motoko, Kuns, Rachel D., Lineburg, Katie E., Wilson, Yana A., Olver, Stuart D., Raffelt, Neil C., Don, Alistair L. J., Varelias, Antiopi, Robb, Renee J., Cheong, Melody, Engwerda, Christian R., Steptoe, Raymond J., Ramshaw, Hayley S., Lopez, Angel F., Vega-Ramos, Javier, Lew, Andrew M., Villadangos, Jose A., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2012). Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood, 119 (24), 5918-5930. doi: 10.1182/blood-2011-12-398164
2012
Journal Article
The interferon-dependent orchestration of innate and adaptive immunity after transplantation
Robb, R.J. and Hill, G.R. (2012). The interferon-dependent orchestration of innate and adaptive immunity after transplantation. Blood, 119 (23), 5351-5358. doi: 10.1182/blood-2012-02-368076
2012
Journal Article
Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease
Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Raffelt, Neil C., Wilson, Yana A., Don, Alistair L. J., Lineburg, Katie E., Cheong, Melody, Robb, Renee J., Markey, Kate A., Varelias, Antiopi, Malissen, Bernard, Hammerling, Gunter J., Clouston, Andrew D., Engwerda, Christian R., Bhat, Purnima, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2012). Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nature Medicine, 18 (1), 135-142. doi: 10.1038/nm.2597
2012
Journal Article
The IL-17 Differentiation Pathway and Its Role in Transplant Outcome
Serody, J.S. and Hill, G.R. (2012). The IL-17 Differentiation Pathway and Its Role in Transplant Outcome. Biology of Blood and Marrow Transplantation, 18 (1 SUPPL.), S56-S61. doi: 10.1016/j.bbmt.2011.10.001
2012
Conference Publication
Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd
Koyama, M., Kuns, R. D., Olver, S. D., Raffelt, N. C., Wilson, YA, Don, A. L. J., Lineburg, K. E., Robb, R. J., Markey, K. A., Varelias, A., Malissen, B., Hammerling, G. J., Bhat, P., Clouston, A. D., Engwerda, C. R., MacDonald, K. P. A. and Hill, G. R. (2012). Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd. BMT Tandem Meeting, San Diego, CA, United States, 01-05 Feburary 2012. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.bbmt.2011.12.422
2011
Journal Article
Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression
Banovic, Tatjana, Yanilla, Mayonelo, Simmons, Russell, Robertson, Ian, Schroder, Wayne A., Raffelt, Neil. C., Wilson, Yana A., Hill, Geoffrey R., Hogan, Patrick and Nourse, Clare B. (2011). Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression. Journal of Infectious Diseases, 204 (12), 1893-1901. doi: 10.1093/infdis/jir660
2011
Journal Article
Vaccinating donors to improve GVL
Hill, Geoffrey R. (2011). Vaccinating donors to improve GVL. Blood, 118 (22), 5720-5721. doi: 10.1182/blood-2011-10-381160
2011
Journal Article
Critical roles for LIGHT and its Receptors in Generating T cell-mediated immunity during Leishmania donovani infection
Stanley, Amanda C., Rivera, Fabian de Labastida, Haque, Ashraful, Sheel, Meru, Zhou, Yonghong, Amante, Fiona H., Bunn, Patrick T., Randall, Louise M., Pfeffer, Klaus, Scheu, Stefanie, Hickey, Michael J., Saunders, Bernadette M., Ware, Carl, Hill, Geoff R., Tamada, Koji, Kaye, Paul M. and Engwerda, Christian R. (2011). Critical roles for LIGHT and its Receptors in Generating T cell-mediated immunity during Leishmania donovani infection. PLoS Pathogens, 7 (10) e1002279, 1-15. doi: 10.1371/journal.ppat.1002279
2011
Journal Article
Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation
O'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727
2011
Journal Article
Type I-IFNs control GVHD and GVL responses after transplantation
Robb, Renee J., Kreijveld, Ellen, Kuns, Rachel D., Wilson, Yana A., Olver, Stuart D., Don, Alistair L. J., Raffelt, Neil C., De Weerd, Nicole A., Lineburg, Katie E., Varelias, Antiopi, Markey, Kate A., Koyama, Motoko, Clouston, Andrew D., Hertzog, Paul J., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2011). Type I-IFNs control GVHD and GVL responses after transplantation. Blood, 118 (12), 3399-3409. doi: 10.1182/blood-2010-12-325746
2011
Journal Article
Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection
Haque, Ashraful, Best, Shannon E., Ammerdorffer, Anne, Desbarrieres, Laure, de Oca, Marcela Montes, Amante, Fiona H., Rivera, Fabian de Labastida, Hertzog, Paul, Boyle, Glen M., Hill, Geoffrey R. and Engwerda, Christian R. (2011). Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection. European Journal of Immunology, 41 (9), 2688-2698. doi: 10.1002/eji.201141539
2011
Journal Article
CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis
McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108
2011
Journal Article
Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation
Tawara, Isao, Koyama, Motoko, Liu, Chen, Toubai, Tomomi, Thomas, Dafydd, Evers, Rebecca, Chockley, Peter, Nieves, Evelyn, Sun, Yaping, Lowler, Kathleen P., Malter, Chelsea, Nishimoto, Norihiro, Hill, Geoffrey R. and Reddy, Pavan (2011). Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation. Clinical Cancer Research, 17 (1), 77-88. doi: 10.1158/1078-0432.CCR-10-1198
Supervision
Availability
- Honorary Professor Geoffrey Hill is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2019
Doctor Philosophy
Restoring myeloma-immune equilibrium by stem cell transplantation
Principal Advisor
-
2019
Doctor Philosophy
Understanding the role of IL-6 signalling in Graft-Versus-Host Disease (GVHD)
Principal Advisor
-
2019
Doctor Philosophy
Anti-leukaemia effect of Interferons
Principal Advisor
Other advisors: Professor Steven Lane
-
2012
Doctor Philosophy
Mechanisms of Immune Modulation after Stem Cell Transplantation
Principal Advisor
-
2021
Doctor Philosophy
Interplay between cytomegalovirus infection and graft-versus-leukaemia effect
Associate Advisor
-
2019
Doctor Philosophy
The contribution of cytokine signals, autophagy and antigen presentation to complications associated with allogeneic stem cell transplantation
Associate Advisor
-
2019
Doctor Philosophy
The Psychosocial Impact of Haematopoietic Stem Cell Donation on Adult Related Donors
Associate Advisor
-
2017
Doctor Philosophy
Maintenance of blood stem cells and the development of haematological malignancies
Associate Advisor
Other advisors: Professor Steven Lane
-
2016
Doctor Philosophy
Stem Cell Therapies and Radiological Imaging in Ataxia Telangiectasia
Associate Advisor
Other advisors: Professor Ernst Wolvetang
-
2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Professor Kiarash Khosrotehrani
-
2012
Doctor Philosophy
T cell immune response to human cytomegalovirus in latency and reactivation
Associate Advisor
-
2012
Doctor Philosophy
Self-renewal pathways in leukaemia stem cells and haematopoietic stem cells
Associate Advisor
-
2011
Doctor Philosophy
Antigen Presentation and Inflammation in Allogeneic Bone Marrow Transplantation
Associate Advisor
-
2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Associate Advisor
Other advisors: Professor Ian Frazer
Media
Enquiries
For media enquiries about Honorary Professor Geoffrey Hill's areas of expertise, story ideas and help finding experts, contact our Media team: