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2025 Journal Article CSF-1R inhibition and lenalidomide synergize to promote myeloma control after autologous stem cell transplantationMinnie, Simone, Adams, Rachael, Ensbey, Kathleen, Schmidt, Christine, Comstock, Melissa, Lyons, Justina, Legg, Samuel, Sekiguchi, Tomoko, Nemychenkov, Nicole, Boiko, Julie, Koyama, Motoko, Spencer, Andrew, Green, Damian and Hill, Geoff (2025). CSF-1R inhibition and lenalidomide synergize to promote myeloma control after autologous stem cell transplantation. Blood, 146 (Supplement 1), 689-689. doi: 10.1182/blood-2025-689 |
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2025 Journal Article CSF-1R+ macrophages orchestrate human skin chronic graft-versus-host diseaseBoiko, Julie, Jones, Daniel, Elz, Anna, Long, Annalyssa, Sowerby, David, Adams, Rachael, MacDonald, Kelli, Blazar, Bruce, Timmers, Cynthia, Pratta, Michael, Ordentlich, Peter, Radojcic, Vedran, Hall, A. Marcie, Furlan, Scott, Lee, Stephanie, Newell, Evan and Hill, Geoff (2025). CSF-1R+ macrophages orchestrate human skin chronic graft-versus-host disease. Blood, 146 (Supplement 1), 588-588. doi: 10.1182/blood-2025-588 |
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2025 Journal Article Multiplex detection of gastrointestinal microbiota using short probes in graft vs. host diseaseYeh, Albert, Long, Annalyssa, Sierra, David, Kong, Paul, Ensbey, Kathleen, Legg, Samuel, Sekiguchi, Tomoko, Bencomo, Tomas, Elz, Anna, Dey, Neelendu, Rashidi, Armin, Markey, Kate, Fredricks, David, Hockenbery, David and Hill, Geoff (2025). Multiplex detection of gastrointestinal microbiota using short probes in graft vs. host disease. Blood, 146 (Supplement 1), 2311-2311. doi: 10.1182/blood-2025-2311 |
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2025 Journal Article IFNγ-driven MHC class II expression by intestinal epithelial cells dictates local cytolytic Th1 cell differentiation and intestinal stem cell lossKoyama, Motoko, Yeh, Albert, Ensbey, Kathleen, Bhise, Shruti, Schuster, Iona, Legg, Samuel, Nelson, Ethan, Sekiguchi, Tomoko, Nemychenkov, Nicole, Takahashi, Shuichiro, Zhang, Ping, Minnie, Simone, Haeseleer, Francoise, Hippe, Daniel, Degli-Esposti, Mariapia, Furlan, Scott and Hill, Geoff (2025). IFNγ-driven MHC class II expression by intestinal epithelial cells dictates local cytolytic Th1 cell differentiation and intestinal stem cell loss. Blood, 146 (Supplement 1), 159-159. doi: 10.1182/blood-2025-159 |
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2025 Journal Article Impaired viral antigen-specific CD8 T cell responses lead to uncontrolled viral replication in lung tissues in PVM-infected allogeneic bone marrow transplant recipients 4420Hamann, Sophie C., Collinge, Alika D., Olver, Stuart D., Kuns, Rachel D., Yeh, Albert C., Minnie, Simone A., Clouston, Andrew D., Spann, Kirsten M., Phipps, Simon, Degli-Esposti, Mariapia A., Hill, Geoff R., Bialasiewicz, Seweryn and Varelias, Antiopi (2025). Impaired viral antigen-specific CD8 T cell responses lead to uncontrolled viral replication in lung tissues in PVM-infected allogeneic bone marrow transplant recipients 4420. The Journal of Immunology, 214 (Supplement_1) vkaf283.2104. doi: 10.1093/jimmun/vkaf283.2104 |
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2025 Journal Article Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomesZhang, Ping, Haeseleer, Françoise, Waltner, Olivia G., Gartlan, Kate H., Bhise, Shruti S., Minnie, Simone A., Adams, Rachael C., Yeh, Albert C., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Atilla, Erden, Nemychenkov, Nicole S., Nelson, Ethan L., Joshi, Tanvi, Liang, Emily C., Hirayama, Alexandre V., Abe, Kokoro, Koyama, Motoko, Clouston, Andrew D., Gauthier, Jordan, Furlan, Scott N. and Hill, Geoffrey R. (2025). Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes. Immunity, 58 (12), 3024-3039.e7. doi: 10.1016/j.immuni.2025.09.004 |
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2025 Conference Publication Spatial Transcriptomics in Extramedullary Multiple Myeloma Reveals an M2 Macrophage Prominent TMEBingham, Nicholas, Boiko, Julie, Jones, Daniel, Ensbey, Kathleen, Elz, Anna, Newell, Evan, Spencer, Andrew and Hill, Geoffrey R. (2025). Spatial Transcriptomics in Extramedullary Multiple Myeloma Reveals an M2 Macrophage Prominent TME. International Myeloma Society 22nd Annual Meeting and Exposition, Toronto, Canada, 17-20 September 2025. New York, NY United States: Elsevier. doi: 10.1016/s2152-2650(25)03677-8 |
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2025 Journal Article Effect of fecal microbiota transplantation on gut microbiota functional profile in recipients of allogeneic hematopoietic cell transplantationEbadi, Maryam, Reddi, Swetha, Senyshyn, Liliia, Minot, Samuel S., Gooley, Ted, Kabage, Amanda J., Lee, Stephanie J., Hill, Geoffrey R., Khoruts, Alexander and Rashidi, Armin (2025). Effect of fecal microbiota transplantation on gut microbiota functional profile in recipients of allogeneic hematopoietic cell transplantation. Gut Microbes, 17 (1) 2551882. doi: 10.1080/19490976.2025.2551882 |
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2025 Journal Article Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCTMcManus, Duneia, Copsel, Sabrina N, Pfeiffer, Brent J, Wolf, Dietlinde, Barreras, Henry, Ma, Symon, Khodor, Ali, Komai, Seitaro, Burgos da Silva, Marina, Hazime, Hajar, Gallardo, Miguel, Lime, Sarah Grace R, van den Brink, Marcel R.M., Park, Jung-Hyun, Abreu, Maria T, Hill, Geoffrey R, Perez, Victor L and Levy, Robert B (2025). Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues, ameliorating GVHD post-HSCT. Blood Journal, 146 (22) blood.2025028418, 2710-2727. doi: 10.1182/blood.2025028418 |
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2025 Journal Article Graft-versus-Host Disease Prophylaxis with Cyclophosphamide and CyclosporinCurtis, David J., Patil, Sushrut S., Reynolds, John, Purtill, Duncan, Lewis, Clinton, Ritchie, David S., Gottlieb, David J., Yeung, David T., Wong, Eric, Tey, Siok-Keen, Perera, Travis, Moore, John, Koldej, Rachel M., De Abreu Lourenco, Richard, Stubbs, John, Morrissey, C. Orla, Munsef, Nadia, Arenas, Andrea and Hill, Geoffrey R. (2025). Graft-versus-Host Disease Prophylaxis with Cyclophosphamide and Cyclosporin. New England Journal of Medicine, 393 (3), 243-254. doi: 10.1056/NEJMoa2503189 |
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2025 Journal Article NIH Chronic Graft-versus-Host Disease Consensus Conference 2025 UpdateLee, Stephanie J, Williams, Kirsten M, Sarantopoulos, Stefanie, Kitko, Carrie L, Cutler, Corey, Pidala, Joseph, Hill, Geoffrey R., DeFilipp, Zachariah, Greinix, Hildegard T, Wolff, Daniel, Paczesny, Sophie, Cuvelier, Geoffrey D E, Schultz, Kirk R and Pavletic, Steven Z (2025). NIH Chronic Graft-versus-Host Disease Consensus Conference 2025 Update. Transplantation and Cellular Therapy, 31 (9), 678.e1-678.e16. doi: 10.1016/j.jtct.2025.05.016 |
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2025 Journal Article Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host diseaseBoiko, Julie R., Ensbey, Kathleen S., Waltner, Olivia G., Jenkins, Isaac C., Bhise, Shruti S., MacDonald, Kelli P.A., Blazar, Bruce R., Hall, Anne Marcie, Gooley, Ted A., Minnie, Simone A., Lee, Stephanie J., Furlan, Scott N. and Hill, Geoffrey R. (2025). Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease. Blood Journal, 145 (19), 2214-2228. doi: 10.1182/blood.2024025337 |
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2025 Journal Article Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHDZaiken, Michael C., Jin, Sujeong, McDonald-Hyman, Cameron, Hartigan, Christina, Sage, Peter, Hippen, Keli L., Koehn, Brent H, Panoskaltsis-Mortari, Angela, Riddle, Megan J, Eide, Cindy, Tolar, Jakub, Hill, Geoffrey R, Luznik, Leo, Cutler, Corey S., Ritz, Jerome, Kean, Leslie S, Tsagaratou, Ageliki, Rao, Anjana and Blazar, Bruce R (2025). Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD. Blood Journal, 145 (24), 2813-2827. doi: 10.1182/blood.2024025036 |
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2025 Journal Article Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effectReddi, Swetha, Senyshyn, Liliia, Ebadi, Maryam, Podlesny, Daniel, Minot, Samuel S., Gooley, Ted, Kabage, Amanda J., Hill, Geoffrey R., Lee, Stephanie J., Khoruts, Alexander and Rashidi, Armin (2025). Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect. Nature Communications, 16 (1) 1034. doi: 10.1038/s41467-025-56375-y |
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2025 Journal Article Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapyCoffey, David G., Atilla, Pinar Ataca, Atilla, Erden, Landgren, Ola, Cowan, Andrew J., Simon, Sylvain, Pont, Margot, Comstock, Melissa L., Hill, Geoffrey R., Riddell, Stanley R. and Green, Damian J. (2025). Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy. Blood Journal, 145 (2), 220-233. doi: 10.1182/blood.2024025231 |
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2024 Journal Article Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ TransplantationBoiko, Julie R. and Hill, Geoffrey R. (2024). Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation. Transplantation, 109 (6), 1-12. doi: 10.1097/tp.0000000000005298 |
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2024 Journal Article The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy OutcomesAdams, Rachael C., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2024). The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy Outcomes. Blood Journal, 145 (10), 1010-1021. doi: 10.1182/blood.2024025680 |
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2024 Conference Publication Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I TrialKrakow, Elizabeth, Connelly-Smith, Laura, Lee, Catherine J., Dunbar, Dow, Barton, Jeremy, McQueen, Beatrice P., Hill, Geoffrey R. and Appelbaum, Jacob S. (2024). Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-204129 |
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2024 Conference Publication Cytokines associated with organ manifestations in chronic graft-versus-host diseaseLee, Stephanie J., Ma, Ningxin, Randolph, Timothy, Kitko, Carrie L., Cutler, Corey S., El Jurdi, Najla, Chen, George, Hamilton, Betty K., Pidala, Joseph A., Carpenter, Paul A., Arai, Sally, Onstad, Lynn, Paczesny, Sophie, Sekiguchi, Tomoko, Koyama, Motoko and Hill, Geoffrey R. (2024). Cytokines associated with organ manifestations in chronic graft-versus-host disease. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-203743 |
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2024 Conference Publication Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized TrialRashidi, Armin, Reddi, Swetha, Ebadi, Maryam, Senyshyn, Liliia, Kabage, Amanda, Minot, Samuel, Gooley, Ted, Lee, Stephanie J., Hill, Geoffrey R. and Khoruts, Alexander (2024). Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-202112 |
