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2025 Journal Article Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host diseaseBoiko, Julie R, Ensbey, Kathleen S., Waltner, Olivia G, Jenkins, Isaac C, Bhise, Shruti S, MacDonald, Kelli PA, Blazar, Bruce R, Hall, Anne Marcie, Gooley, Ted A, Minnie, Simone A, Lee, Stephanie J., Furlan, Scott N and Hill, Geoffrey R (2025). Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease. Blood Journal. doi: 10.1182/blood.2024025337 |
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2025 Journal Article Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHDZaiken, Michael C., Jin, Sujeong, McDonald-Hyman, Cameron, Hartigan, Christina, Sage, Peter, Hippen, Keli L., Koehn, Brent H, Panoskaltsis-Mortari, Angela, Riddle, Megan J, Eide, Cindy, Tolar, Jakub, Hill, Geoffrey R, Luznik, Leo, Cutler, Corey S., Ritz, Jerome, Kean, Leslie S, Tsagaratou, Ageliki, Rao, Anjana and Blazar, Bruce R (2025). Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD. Blood Journal. doi: 10.1182/blood.2024025036 |
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2025 Journal Article Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effectReddi, Swetha, Senyshyn, Liliia, Ebadi, Maryam, Podlesny, Daniel, Minot, Samuel S., Gooley, Ted, Kabage, Amanda J., Hill, Geoffrey R., Lee, Stephanie J., Khoruts, Alexander and Rashidi, Armin (2025). Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect. Nature Communications, 16 (1) 1034, 1. doi: 10.1038/s41467-025-56375-y |
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2024 Journal Article Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ TransplantationBoiko, Julie R. and Hill, Geoffrey R. (2024). Chronic Graft-versus-host Disease: Immune Insights, Therapeutic Advances, and Parallels for Solid Organ Transplantation. Transplantation, 1-12. doi: 10.1097/tp.0000000000005298 |
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2024 Journal Article The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy OutcomesAdams, Rachael C, MacDonald, Kelli PA and Hill, Geoffrey R (2024). The Contribution of the Monocyte-Macrophage Lineage to Immunotherapy Outcomes. Blood Journal, 145 (10), 1010-1021. doi: 10.1182/blood.2024025680 |
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2024 Conference Publication Donor XCR1+ and CD11b+ Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal TractKoyama, Motoko, Takahashi, Shuichiro, Inoue, Takayuki, Ensbey, Kathleen S., Legg, Samuel R. W., Sekiguchi, Tomoko, Nelson, Ethan, Nemychenkov, Nicole S., Joshi, Tanvi, Minnie, Simone A., Yeh, Albert C., Boiko, Julie R., Zhang, Ping, Headley, Mark B., Paik, Jisun, Amory, John K. and Hill, Geoffrey R. (2024). Donor XCR1+ and CD11b+ Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-209473 |
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2024 Conference Publication Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I TrialKrakow, Elizabeth, Connelly-Smith, Laura, Lee, Catherine J., Dunbar, Dow, Barton, Jeremy, McQueen, Beatrice P., Hill, Geoffrey R. and Appelbaum, Jacob S. (2024). Trials in Progress: Decoy-Resistant Interleukin-18 (DR-18) for Relapse or Pre-Emptive Treatment of Measurable Residual Disease after Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome (DR. DREAM), a Phase I Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-204129 |
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2024 Conference Publication Cytokines associated with organ manifestations in chronic graft-versus-host diseaseLee, Stephanie J., Ma, Ningxin, Randolph, Timothy, Kitko, Carrie L., Cutler, Corey S., El Jurdi, Najla, Chen, George, Hamilton, Betty K., Pidala, Joseph A., Carpenter, Paul A., Arai, Sally, Onstad, Lynn, Paczesny, Sophie, Sekiguchi, Tomoko, Koyama, Motoko and Hill, Geoffrey R. (2024). Cytokines associated with organ manifestations in chronic graft-versus-host disease. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-203743 |
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2024 Conference Publication Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized TrialRashidi, Armin, Reddi, Swetha, Ebadi, Maryam, Senyshyn, Liliia, Kabage, Amanda, Minot, Samuel, Gooley, Ted, Lee, Stephanie J., Hill, Geoffrey R. and Khoruts, Alexander (2024). Fecal Microbiota Transplantation to Prevent Acute Graft-Versus-Host Disease: First Pre-Planned Interim Analysis of a Randomized Trial. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-202112 |
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2024 Conference Publication Trial in Progress: ST-067 (decoy-resistant IL-18) with Teclistamab in Multiple MyelomaBanerjee, Rahul, Vandermeer, Jacquelin, Barton, Jeremy, Mangone, Michael, McQueen, Beatrice P., Gauthier, Jordan, Ring, Aaron M, Gopal, Ajay K., Hill, Geoffrey R. and Cowan, Andrew J. (2024). Trial in Progress: ST-067 (decoy-resistant IL-18) with Teclistamab in Multiple Myeloma. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-198751 |
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2024 Journal Article Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. ReplyZhang, Ping, Minnie, Simone A. and Hill, Geoffrey R. (2024). Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply. Journal of Clinical Investigation, 134 (20), 20. doi: 10.1172/jci184869 |
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2024 Journal Article Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapyCoffey, David G, Atilla, Pinar Ataca, Atilla, Erden, Landgren, Ola, Cowan, Andrew J, Simon, Sylvain, Pont, Margot, Comstock, Melissa L., Hill, Geoffrey R, Riddell, Stanley R. and Green, Damian J (2024). Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy. Blood Journal, 145 (2), 220-233. doi: 10.1182/blood.2024025231 |
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2024 Conference Publication Autocrine IL6 Signaling in Stromal Cells in Multiple Myeloma Influences the Bone Marrow MicroenvironmentMatulis, Shannon, Barwick, Benjamin G., Bombin, Sergei, Ackley, James, Gupta, Vikas, Hill, Geoffrey, Green, Damian, Riddell, Stanley, Lonial, Sagar, Dhodapkar, Madhav V. and Boise, Lawrence (2024). Autocrine IL6 Signaling in Stromal Cells in Multiple Myeloma Influences the Bone Marrow Microenvironment. International Myeloma Society 21st Annual Meeting and Exposition, Rio de Janeiro, Brazil, 25-28 September 2024. New York, NY United States: Elsevier. doi: 10.1016/s2152-2650(24)02137-2 |
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2024 Journal Article CMV reactivation during pre-transplantation evaluation: a novel risk factor for post-transplantation CMV reactivationZamora, Danniel, Xie, Hu, Sadowska-Klasa, Alicja, Kampouri, Eleftheria, Biernacki, Melinda A, Ueda Oshima, Masumi, Duke, Elizabeth R, Green, Margaret L., Kimball, Louise, Holmberg, Leona A, Waghmare, Alpana, Greninger, Alexander L, Jerome, Keith R, Hill, Geoffrey R, Hill, Joshua A, Leisenring, Wendy M and Boeckh, Michael J (2024). CMV reactivation during pre-transplantation evaluation: a novel risk factor for post-transplantation CMV reactivation. Blood Advances, 8 (17), 4568-4580. doi: 10.1182/bloodadvances.2023012234 |
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2024 Journal Article Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantationYeh, Albert C., Koyama, Motoko, Waltner, Olivia G., Minnie, Simone A., Boiko, Julie R., Shabaneh, Tamer B., Takahashi, Shuichiro, Zhang, Ping, Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Nelson, Ethan, Bhise, Shruti S., Stevens, Andrew R., Goodpaster, Tracy, Chakka, Saranya, Furlan, Scott N., Markey, Kate A., Bleakley, Marie E., Elson, Charles O., Bradley, Philip H. and Hill, Geoffrey R. (2024). Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation. Immunity, 57 (7), 1648-1664.e9. doi: 10.1016/j.immuni.2024.05.018 |
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2024 Journal Article Clinical grade multiparametric cell sorting and gene-marking of regulatory T cellsEkwe, Adaeze Precious, Au, Raymond, Zhang, Ping, McEnroe, Benjamin, Tan, Mei Ling, Saldan, Alda, Henden, Andrea S., Hutchins, Cheryl, Henderson, Ashleigh, Mudie, Kari, Kerr, Keri, Fuery, Madonna, Kennedy, Glen A., Hill, Geoffrey R. and Tey, Siok-Keen (2024). Clinical grade multiparametric cell sorting and gene-marking of regulatory T cells. Cytotherapy, 26 (7), 719-728. doi: 10.1016/j.jcyt.2024.02.023 |
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2024 Journal Article Autophagy prevents graft failure during murine Graft versus Host DiseaseLineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972 |
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2024 Journal Article TIM-3<SUP>+</SUP> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignanciesMinnie, Simone A., Waltner, Olivia G., Zhang, Ping, Takahashi, Shuichiro, Nemychenkov, Nicole S., Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R. W., Comstock, Melissa, Boiko, Julie R., Nelson, Ethan, Bhise, Shruti S., Wilkens, Alec B., Koyama, Motoko, Dhodapkar, Madhav V., Chesi, Marta, Riddell, Stanley R., Green, Damian J., Spencer, Andrew, Furlan, Scott N. and Hill, Geoffrey R. (2024). TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies. Science Immunology, 9 (94) eadg1094, eadg1094. doi: 10.1126/sciimmunol.adg1094 |
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2024 Journal Article Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantationTakahashi, Shuichiro, Minnie, Simone A., Ensbey, Kathleen S., Schmidt, Christine R., Sekiguchi, Tomoko, Legg, Samuel R. W., Zhang, Ping, Koyama, Motoko, Olver, Stuart D., Collinge, Alika D., Keshmiri, Sara, Comstock, Melissa L., Varelias, Antiopi, Green, Damian J. and Hill, Geoffrey R. (2024). Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Blood, 143 (16), 1656-1669. doi: 10.1182/blood.2023022000 |
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2024 Journal Article IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantationZhang, Ping, Fleming, Peter, Andoniou, Christopher E., Waltner, Olivia G., Bhise, Shruti S., Martins, Jose Paulo, McEnroe, Benjamin A., Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D., Ekwe, Adaeze P., Henden, Andrea S., Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Minnie, Simone A., Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D., Koyama, Motoko, Furlan, Scott N., Kennedy, Glen A., Ward, E Sally, Degli-Esposti, Mariapia A. ... Tey, Siok-Keen (2024). IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. Journal of Clinical Investigation, 134 (7) e174184, 1-15. doi: 10.1172/jci174184 |
