Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

310 works between 1996 and 2025
All (310) Journal Article (270) Conference Publication (38) Book Chapter (2)

81 - 100 of 310 works

2020

Conference Publication

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

Minnie, Simone A., Kuns, Rachel D., Ensbey, Kathleen S., Samson, Luke D., Chesi, Marta, Gartlan, Kate H., Smyth, Mark J., Vuckovic, Slavica and Hill, Geoffrey R. (2020). Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.30

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

2020

Conference Publication

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

Aguilar, Ethan George, Rhee, Stephanie, Thangavelu, Govindarajan, Loschi, Michael, Paz, Katelyn, Saha, Asim, Ly, Joanna, Sage, Peter, Sharpe, Arlene H., Maillard, Ivan, Murphy, William J., Serody, Jonathan S., Jin, Suji, Wagers, Sara Bolivar, Nicholls, Jemma, Hill, Geoffrey, MacDonald, Kelli P.A., Compeer, Ewoud, Dustin, Michael, O’Connor, Roddy, Sparwasser, Tim and Blazar, Bruce R. (2020). Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD). Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.2

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

2020

Journal Article

Immunotherapy of multiple myeloma

Minnie, Simone A. and Hill, Geoffrey R. (2020). Immunotherapy of multiple myeloma. The Journal of Clinical Investigation, 130 (4), 1565-1575. doi: 10.1172/JCI129205

Immunotherapy of multiple myeloma

2020

Journal Article

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

Kumar, Rajiv, Bunn, Patrick T., Singh, Siddharth Sankar, Ng, Susanna S., Montes de Oca, Marcela, De Labastida Rivera, Fabian, Chauhan, Shashi Bhushan, Singh, Neetu, Faleiro, Rebecca J., Edwards, Chelsea L., Frame, Teija C.M., Sheel, Meru, Austin, Rebecca J., Lane, Steven W., Bald, Tobias, Smyth, Mark J., Hill, Geoffrey.R., Best, Shannon E., Haque, Ashraful, Corvino, Dillon, Waddell, Nic, Koufariotis, Lambross, Mukhopadhay, Pamela, Rai, Madhukar, Chakravarty, Jaya, Singh, Om Prakash, Sacks, David, Nylen, Susanne, Uzonna, Jude ... Engwerda, Christian R. (2020). Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis. Cell Reports, 30 (8), 2512-2525.e9. doi: 10.1016/j.celrep.2020.01.099

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

2020

Journal Article

Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma

Lynch, Jason P., Werder, Rhiannon B., Curren, Bodie F., Sikder, Md. Al Amin, Ullah, Ashik, Sebina, Ismail, Rashid, Ridwan B., Zhang, Vivian, Upham, John W., Hill, Geoff R., Steptoe, Raymond J. and Phipps, Simon (2020). Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma. Mucosal Immunology, 13 (4), 652-664. doi: 10.1038/s41385-020-0268-8

Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma

2020

Journal Article

Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice

Bowerman, Kate L., Varelias, Antiopi, Lachner, Nancy, Kuns, Rachel D., Hill, Geoffrey R. and Hugenholtz, Philip (2020). Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice. Gut Microbes, 11 (4), 1-17. doi: 10.1080/19490976.2019.1705729

Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice

2020

Journal Article

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Thangavelu, Govindarajan, Du, Jing, Paz, Katelyn G., Loschi, Michael, Zaiken, Michael C., Flynn, Ryan, Taylor, Patricia A., Kirchmeier, Andrew Kemal, Panoskaltsis-Mortari, Angela, Luznik, Leo, MacDonald, Kelli P., Hill, Geoffrey R., Maillard, Ivan, Munn, David H., Serody, Jonathan S., Murphy, William J., Miklos, David, Cutler, Corey S., Koreth, John, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Dahlberg, Carol, Miller, Andrew T. and Blazar, Bruce R. (2020). Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease. Blood, 135 (1), 28-40. doi: 10.1182/blood.2019000032

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

2019

Journal Article

The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host disease

Koyama, Motoko and Hill, Geoffrey R. (2019). The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host disease. Blood, 134 (24), 2139-2148. doi: 10.1182/blood.2019000823

The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host disease

2019

Journal Article

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce B., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota. Immunity, 51 (5), 885-898. doi: 10.1016/j.immuni.2019.08.011

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

2019

Journal Article

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

Austin, Rebecca J., Straube, Jasmin, Bruedigam, Claudia, Pali, Gabor, Jacquelin, Sebastien, Vu, Therese, Green, Joanne, Gräsel, Julius, Lansink, Lianne, Cooper, Leanne, Lee, Shin-Jye, Chen, Nien-Tsu, Lee, Chung-Wei, Haque, Ashraful, Heidel, Florian H., D’Andrea, Richard, Hill, Geoff R., Mullally, Ann, Milsom, Michael D., Bywater, Megan and Lane, Steven W. (2019). Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations. Leukemia, 34 (4), 1075-1089. doi: 10.1038/s41375-019-0638-y

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

2019

Journal Article

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, Brent H., Saha, Asim, McDonald-Hyman, Cameron, Loschi, Michael, Thangavelu, Govindarajan, Ma, Lie, Zaiken, Michael, Dysthe, Josh, Krepps, Walker, Panthera, Jamie, Hippen, Keli, Jameson, Stephen C., Miller, Jeffrey S., Cooper, Matthew A., Farady, Christopher J., Iwawaki, Takao, Ting, Jenny P-Y, Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Murray, Peter J., Bronte, Vincenzo, Munn, David H., Zeiser, Robert and Blazar, Bruce R. (2019). Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD. Blood, 134 (19), 1670-1682. doi: 10.1182/blood.2019001950

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

2019

Journal Article

Pegylated interferon-2 alpha invokes graft-versus-leukemia effects in patients relapsing after allogeneic stem cell transplantation

Henden, Andrea S., Varelias, Antiopi, Leach, Justine, Sturgeon, Elise, Avery, Judy, Kelly, Jessica, Olver, Stuart, Samson, Luke, Hartel, Gunter, Durrant, Simon, Butler, Jason, Morton, Anthony J., Misra, Ashish, Tey, Siok-Keen, Subramoniapillai, Elango, Curley, Cameron, Kennedy, Glen and Hill, Geoffrey R. (2019). Pegylated interferon-2 alpha invokes graft-versus-leukemia effects in patients relapsing after allogeneic stem cell transplantation. Blood Advances, 3 (20), 3013-3019. doi: 10.1182/bloodadvances.2019000453

Pegylated interferon-2 alpha invokes graft-versus-leukemia effects in patients relapsing after allogeneic stem cell transplantation

2019

Journal Article

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

Gartlan, Kate H., Koyama, Motoko, Lineburg, Katie E., Chang, Karshing, Ensbey, Kathleen S., Kuns, Rachel D., Henden, Andrea S., Samson, Luke D., Clouston, Andrew D., Lopez, Angel F., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2019). Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract. Blood Advances, 3 (19), 2859-2865. doi: 10.1182/bloodadvances.2019000053

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

2019

Journal Article

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, Asim, Taylor, Patricia A., Lees, Christopher J., Panoskaltsis-Mortari, Angela, Osborn, Mark J., Feser, Colby J., Thangavelu, Govindarajan, Melchinger, Wolfgang, Refaeli, Yosef, Hill, Geoffrey R., Munn, David H., Murphy, William J., Serody, Jonathan S., Maillard, Ivan, Kreymborg, Katharina, van den Brink, Marcel, Dong, Chen, Huang, Shuyu, Zang, Xingxing, Allison, James P., Zeiser, Robert and Blazar, Bruce R. (2019). Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. JCI insight, 4 (19) e127716. doi: 10.1172/jci.insight.127716

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

2019

Journal Article

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

Wilkinson, Andrew N., Chang, Karshing, Kuns, Rachel D., Henden, Andrea S., Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew D., Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica, Gartlan, Kate H. and Hill, Geoffrey R. (2019). IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling. Blood, 134 (23), 2092-2106. doi: 10.1182/blood.2019000396

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

2019

Journal Article

Inhibition of the cytolytic protein perforin prevents rejection of transplanted bone marrow stem cells in vivo

Spicer, Julie A., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Giddens, Anna C., Jaiswal, Jagdish K., Jamieson, Stephen M. F., Bull, Matthew R., Denny, William A., Akhlaghi, Hedieh, Trapani, Joseph A., Hill, Geoff R., Chang, Karshing and Gartlan, Kate H. (2019). Inhibition of the cytolytic protein perforin prevents rejection of transplanted bone marrow stem cells in vivo. Journal of Medicinal Chemistry, 63 (5) acs.jmedchem.9b00881, 2229-2239. doi: 10.1021/acs.jmedchem.9b00881

Inhibition of the cytolytic protein perforin prevents rejection of transplanted bone marrow stem cells in vivo

2019

Journal Article

Adult related haematopoietic stem cell donor care: views of transplant nurses

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey R. and Gottlieb, David (2019). Adult related haematopoietic stem cell donor care: views of transplant nurses. European Journal of Oncology Nursing, 41, 56-63. doi: 10.1016/j.ejon.2019.05.012

Adult related haematopoietic stem cell donor care: views of transplant nurses

2019

Journal Article

Interleukin-10 mediated immune regulation after stem cell transplantation: mechanisms and implications for therapeutic intervention

Zhang, Ping and Hill, Geoffrey R. (2019). Interleukin-10 mediated immune regulation after stem cell transplantation: mechanisms and implications for therapeutic intervention. Seminars in Immunology, 44 101322, 101322. doi: 10.1016/j.smim.2019.101322

Interleukin-10 mediated immune regulation after stem cell transplantation: mechanisms and implications for therapeutic intervention

2019

Journal Article

Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model

Guillerey, Camille, Nakamura, Kyohei, Pichler, Andrea C., Barkauskas, Deborah, Krumeich, Sophie, Stannard, Kimberley, Miles, Kim, Harjunpää, Heidi, Yu, Yuan, Casey, Mika, Doban, Alina I., Lazar, Mircea, Hartel, Gunter, Smith, David, Vuckovic, Slavica, Teng, Michele W.L., Bergsagel, P. Leif, Chesi, Marta, Hill, Geoffrey R., Martinet, Ludovic and Smyth, Mark J. (2019). Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model. JCI Insight, 4 (14) :e125932. doi: 10.1172/jci.insight.125932

Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model

2019

Conference Publication

B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality

Saha, Asim, Taylor, Patricia A., Lees, Christopher J., Panoskaltsis-Mortari, Angela, Osborn, Mark J., Feser, Colby J., Thangavelu, Govindarajan, Melchinger, Wolfgang, Refaeli, Yosef, Hill, Geoffrey R., Munn, David H., Serody, Jonathan S., Maillard, Ivan, Kreymborg, Katharina, van den Brink, Marcel, Dong, Chen, Huang, Shuyu, Zang, Xingxing, Allison, James P, Zeiser, Robert and Blazar, Bruce R. (2019). B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.10

B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

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