Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

278 works between 1996 and 2024
All (278) Journal Article (250) Book Chapter (2) Conference Publication (26)

81 - 100 of 278 works

2018

Journal Article

Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade

Minnie, Simone A., Kuns, Rachel D., Gartlan, Kate H., Zhang, Ping, Wilkinson, Andrew N., Samson, Luke, Guillerey, Camille, Engwerda, Christian, MacDonald, Kelli P. A., Smyth, Mark J., Markey, Kate A., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade. Blood, 132 (16), 1675-1688. doi: 10.1182/blood-2018-01-825240

Myeloma escape after stem cell transplantation is a consequence of t-cell exhaustion and is prevented by tigit blockade

2018

Journal Article

Bone marrow transplantation generates T cell–dependent control of myeloma in mice

Vuckovic, Slavica, Minnie, Simone A., Smith, David, Gartlan, Kate H., Watkins, Thomas S., Markey, Kate A., Mukhopadhyay, Pamela, Guillerey, Camille, Kuns, Rachel D., Locke, Kelly R., Pritchard, Antonia L., Johansson, Peter A., Varelias, Antiopi, Zhang, Ping, Huntington, Nicholas D., Waddell, Nicola, Chesi, Marta, Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Bone marrow transplantation generates T cell–dependent control of myeloma in mice. Journal of Clinical Investigation, 129 (1) CI98888, 106-121. doi: 10.1172/jci98888

Bone marrow transplantation generates T cell–dependent control of myeloma in mice

2018

Conference Publication

Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878

Predictors of Negative Psychosocial Outcomes Among Adult Related Stem Cell Donors - An Australian Multicenter Study

2018

Conference Publication

Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey and Gottlieb, David (2018). Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study. 20th World Congress of Psycho‐Oncology, Hong Kong, 29 October-2 November 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/pon.4878

Being a Stem Cell Donor for a Chronically-ill Family Member: Results from an Australian Multicenter Study

2018

Journal Article

TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma

Guillerey, Camille, Harjunpää, Heidi, Carrié, Nadège, Kassem, Sahar, Teo, Tricia, Miles, Kim, Krumeich, Sophie, Weulersse, Marianne, Cuisinier, Marine, Stannard, Kimberley, Yu, Yuan, Minnie, Simone A., Hill, Geoffrey R., Dougall, William C., Avet-Loiseau, Hervé, Teng, Michele W. L., Nakamura, Kyohei, Martinet, Ludovic and Smyth, Mark J. (2018). TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma. Blood, 132 (16), blood-2018. doi: 10.1182/blood-2018-01-825265

TIGIT immune checkpoint blockade restores CD8 T cell immunity against multiple myeloma

2018

Journal Article

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy

Blazar, Bruce R., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2018). Immune regulatory cell infusion for graft-versus-host disease prevention and therapy. Blood, 131 (24), 2651-2660. doi: 10.1182/blood-2017-11-785865

Immune regulatory cell infusion for graft-versus-host disease prevention and therapy

2018

Journal Article

Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease

Takahashi, Shuichiro, Hashimoto, Daigo, Hayase, Eiko, Ogasawara, Reiki, Ohigashi, Hiroyuki, Ara, Takahide, Yokoyama, Emi, Ebata, Ko, Matsuoka, Satomi, Hill, Geoffrey R., Sugita, Junichi, Onozawa, Masahiro and Teshima, Takanori (2018). Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease. Blood, 131 (18), 2074-2085. doi: 10.1182/blood-2017-06-792614

Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease

2018

Conference Publication

Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium

Minnie, Simone, Vuckovic, Slavica, Smith, David, Gartlan, Kate H., Watkins, Thomas S., Kuns, Rachel D., Guillerey, Camille, Chesi, Marta, Markey, Kate A., Miles, John J., Smyth, Mark J. and Hill, Geoffrey R. (2018). Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.19

Syngeneic stem cell transplantation generates antigen-specific T cells that maintain myeloma-immune equilibrium

2018

Conference Publication

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

Varelias, Antiopi, Bunting, Mark, Ormerod, Kate, Koyama, Motoko, Olver, Stuart, Straube, Jasmin, Kuns, Rachel, Robb, Renee, Henden, Andrea, Cooper, Leanne, Lachner, Nancy, Gartlan, Kate, Lantz, Olivier J., Kjer-Nielsen, Lars, Mak, Jeffrey, Fairlie, David, Clouston, Andrew, McCluskey, James, Rossjohn, Jamie, Lane, Steven, Hugenholtz, Phil and Hill, Geoff (2018). Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.15

Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon

2018

Conference Publication

Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo

Wilkinson, Andrew N., Kuns, Rachel D., Varelias, Antiopi, Vuckovic, Slavica, Rose-John, Stefan, Gartlan, Kate H. and Hill, Geoffrey R. (2018). Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.55.2

Distinct IL-6 Signaling Pathways Drive Alternate Pathogenic T Cell Differentiation And GVHD After Transplant In Vivo

2018

Journal Article

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset

Hülsdünker, Jan, Ottmüller, Katja J., Neeff, Hannes P., Koyama, Motoko, Gao, Zhan, Thomas, Oliver S., Follo, Marie, Al-Ahmad, Ali, Prinz, Gabriele, Duquesne, Sandra, Dierbach, Heide, Kirschnek, Susanne, Lämmermann, Tim, Blaser, Martin J., Fife, Brian T., Blazar, Bruce R., Beilhack, Andreas, Hill, Geoffrey R., Häcker, Georg and Zeiser, Robert (2018). Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood, 131 (16), 1858-1869. doi: 10.1182/blood-2017-10-812891

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset

2018

Journal Article

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

Mathew, Nimitha R, Baumgartner, Francis, Braun, Lukas, O'Sullivan, David, Thomas, Simone, Waterhouse, Miguel, Müller, Tony A, Hanke, Kathrin, Taromi, Sanaz, Apostolova, Petya, Illert, Anna L, Melchinger, Wolfgang, Duquesne, Sandra, Schmitt-Graeff, Annette, Osswald, Lena, Yan, Kai-Li, Weber, Arnim, Tugues, Sonia, Spath, Sabine, Pfeifer, Dietmar, Follo, Marie, Claus, Rainer, Lübbert, Michael, Rummelt, Christoph, Bertz, Hartmut, Wäsch, Ralph, Haag, Johanna, Schmidts, Andrea, Schultheiss, Michael ... Zeiser, Robert (2018). Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine, 24 (4), 526-526. doi: 10.1038/nm0418-526c

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

2018

Journal Article

Recipient mucosal-associated invariant T cells control GVHD within the colon

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646

Recipient mucosal-associated invariant T cells control GVHD within the colon

2018

Journal Article

Granulocytes are unresponsive to IL-6 due to an absence of gp130

Wilkinson, Andrew N., Gartlan, Kate H., Kelly, Greg, Samson, Luke D., Olver, Stuart D., Avery, Judy, Zomerdijk, Nienke, Tey, Siok-Keen, Lee, Jason S., Vuckovic, Slavica and Hill, Geoffrey R. (2018). Granulocytes are unresponsive to IL-6 due to an absence of gp130. Journal of Immunology, 200 (9), 3547-3555. doi: 10.4049/jimmunol.1701191

Granulocytes are unresponsive to IL-6 due to an absence of gp130

2018

Journal Article

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

Hardy, Kristine, Smith, Corey, Tu, Wen Juan, McCuaig, Robert, Panikkar, Archana, Dasari, Vijayendra, Wu, Fan, Tey, Siok-Keen, Hill, Geoffrey R., Khanna, Rajiv and Rao, Sudha (2018). Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients. Blood Advances, 2 (6), 656-668. doi: 10.1182/bloodadvances.2018015909

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

2018

Journal Article

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Lane, Steven W. and Hill, Geoffrey R. (2018). Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT. Bone Marrow Transplantation, 53 (6), 800-803. doi: 10.1038/s41409-018-0148-y

Conventional dendritic cells are required for the cross-presentation of leukemia-specific antigen in a model of AML relapse post-BMT

2018

Journal Article

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

Straube, Jasmin, Ling, Victoria Y, Hill, Geoffrey R and Lane, Steven W (2018). The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia. Blood, 131 (10), 1148-1153. doi: 10.1182/blood-2017-09-807438

The impact of age, NPM1, and FLT3 allelic ratio in patients with acute myeloid leukemia

2018

Journal Article

Early blood stream infection after BMT is associated with cytokine dysregulation and poor overall survival

Catchpoole, Elizabeth M., Thirunavukarasu, Caitlin E., Varelias, Antiopi, Schlebusch, Sanmarié, Olver, Stuart, Zomerdijk, Nienke, Osland, Emma, Kennedy, Glen A., Tey, Siok-Keen, Hill, Geoffrey R. and Markey, Kate A. (2018). Early blood stream infection after BMT is associated with cytokine dysregulation and poor overall survival. Biology of Blood and Marrow Transplantation, 24 (7), 1360-1366. doi: 10.1016/j.bbmt.2018.02.025

Early blood stream infection after BMT is associated with cytokine dysregulation and poor overall survival

2018

Journal Article

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

Mathew, Nimitha R., Baumgartner, Francis, Braun, Lukas, O'Sullivan, David, Thomas, Simone, Waterhouse, Miguel, Müller, Tony A., Hanke, Kathrin, Taromi, Sanaz, Apostolova, Petya, Illert, Anna L., Melchinger, Wolfgang, Duquesne, Sandra, Schmitt-Graeff, Annette, Osswald, Lena, Yan, Kai-Li, Weber, Arnim, Tugues, Sonia, Spath, Sabine, Pfeifer, Dietmar, Follo, Marie, Claus, Rainer, Lübbert, Michael, Rummelt, Christoph, Bertz, Hartmut, Wäsch, Ralph, Haag, Johanna, Schmidts, Andrea, Schultheiss, Michael ... Zeiser, Robert (2018). Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine, 24 (3), 282-291. doi: 10.1038/nm.4484

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

2018

Journal Article

Dysregulated IL-18 Is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment

Nakamura, Kyohei, Kassem, Sahar, Cleynen, Alice, Chrétien, Marie-Lorraine, Guillerey, Camille, Putz, Eva Maria, Bald, Tobias, Förster, Irmgard, Vuckovic, Slavica, Hill, Geoffrey R, Masters, Seth L, Chesi, Marta, Bergsagel, P Leif, Avet-Loiseau, Hervé, Martinet, Ludovic and Smyth, Mark J. (2018). Dysregulated IL-18 Is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment. Cancer Cell, 33 (4), 634-648. doi: 10.1016/j.ccell.2018.02.007

Dysregulated IL-18 Is a key driver of immunosuppression and a possible therapeutic target in the multiple myeloma microenvironment

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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