Honorary Professor Geoffrey Hill
Honorary Professor

Geoffrey Hill

Email: 

Background

Professor Geoff Hill MBChB MD BHB FRCPA FRACP geoffH@qimr.edu.au

NHMRC Australia and QLD Health Senior Clinical Research Fellow

Coordinator, Cancer Programme, QIMR Berghofer

Head, Bone Marrow Transplantation Laboratory, QIMR Berghofer

Director of Research, Cancer Care Services, Royal Brisbane & Womens’ Hospital

Bone Marrow Transplant Physician and Haematologist, Royal Brisbane & Womens’ Hospital

Geoff Hill is a medical graduate of the University of Auckland and Haematologist, training in New Zealand, The Dana Farber Cancer Institute in Boston. He is a NHMRC Australia Fellow and his immunology laboratory focuses on the interactions between cytokines, antigen presenting cells and regulatory T cells during transplantation.

Professor Hill was the 2005 Queenslander of the Year and recipient of the Transplantation Society of Australia and New Zealand 2009 Ian McKenzie Award and the 2014 Translational Research Institute National Prize for excellence within basic and clinical research in the transplant field. He was also awarded a Queensland Health Senior Clinical Research Fellowship in 2010 to translate new cytokine and cell based therapies into clinic practice.

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

Fields of research

Clinical sciences Immunology

Qualifications

  • Bachelor, The University of Auckland
  • Masters (Coursework) of Medicine Surgery, The University of Auckland
  • Doctoral Diploma of Medicine, The University of Auckland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Search Professor Geoffrey Hill’s works on UQ eSpace

305 works between 1996 and 2025
All (305) Journal Article (269) Conference Publication (34) Book Chapter (2)

61 - 80 of 305 works

2021

Journal Article

The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models

Teshima, Takanori and Hill, Geoffrey R. (2021). The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models. Frontiers in Immunology, 12 715424. doi: 10.3389/fimmu.2021.715424

The pathophysiology and treatment of graft-versus-host disease: Lessons learnt from animal models

2021

Journal Article

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

Henden, Andrea S., Koyama, Motoko, Robb, Renee J., Forero, Adriana, Kuns, Rachel D., Chang, Karshing, Ensbey, Kathleen S., Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nicole, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey R. (2021). IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood, 138 (8), 722-737. doi: 10.1182/blood.2020006375

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

2021

Journal Article

Current Concepts and Advances in Graft-Versus-Host Disease Immunology

Hill, Geoffrey R., Betts, Brian C., Tkachev, Victor, Kean, Leslie S. and Blazar, Bruce R. (2021). Current Concepts and Advances in Graft-Versus-Host Disease Immunology. Annual Review of Immunology, 39 (1), 19-49. doi: 10.1146/annurev-immunol-102119-073227

Current Concepts and Advances in Graft-Versus-Host Disease Immunology

2021

Journal Article

Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?

Minnie, Simone A. and Hill, Geoffrey R. (2021). Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?. Frontiers in Immunology, 12 651288. doi: 10.3389/fimmu.2021.651288

Autologous stem cell transplantation for myeloma: Cytoreduction or an immunotherapy?

2021

Conference Publication

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

Henden, Andrea S., Robb, Renee, Forero, Adriana, Kuns, Rachel D., Ensbey, Kathleen S., Chang, Karshing, Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nic, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey (2021). Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd. 2021 TCT Meetings of ASTCT and CIBMTR, Online, 8-12 February 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2666-6367(21)00107-x

Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd

2021

Journal Article

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Thangavelu, Govindarajan, Wang, Chao, Loschi, Michael, Saha, Asim, Osborn, Mark J., Furlan, Scott N., Aoyama, Kazutoshi, McDonald-Hyman, Cameron, Aguilar, Ethan G., Janesick, Amanda S., Chandraratna, Roshantha A., Refaeli, Yosef, Panoskaltsis-Mortari, Angela, MacDonald, Kelli P., Hill, Geoffrey R., Zeiser, Robert, Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Blumberg, Bruce, Brown, Chrysothemis, Kuchroo, Vijay, Kean, Leslie S., Hippen, Keli L., Noelle, Randolph J. and Blazar, Bruce R. (2021). Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses. Blood, 137 (8), 1090-1103. doi: 10.1182/blood.2020005628

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

2021

Journal Article

Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach

Ueda Oshima, Masumi, Sandmaier, Brenda M., Petersdorf, Effie, Flowers, Mary E., Hill, Geoffrey R., Lee, Stephanie J., Appelbaum, Frederick R., Carpenter, Paul A., Baker, K. Scott, Connelly-Smith, Laura, McCool, Andrea, Elgar, Suni, Pergam, Steven A., Liu, Catherine, Stewart, F. Marc and Mielcarek, Marco (2021). Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach. Bone Marrow Transplantation, 56 (2), 305-313. doi: 10.1038/s41409-020-01068-x

Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach

2021

Journal Article

A phase 3 double-blind study of the addition of tocilizumab versus placebo to cyclosporin/methotrexate GvHD prophylaxis

Kennedy, Glen, Tey, Siok-Keen, Buizen, Luke, Varelias, Antiopi, Gartlan, Kate H., Curley, Cameron, Olver, Stuart, Chang, Karshing, Butler, Jason, Misra, Ashish, Subramoniapillai, Elango, Morton, Anthony, Durrant, Simon, Henden, Andrea S, Moore, John, Ritchie, David S, Gottlieb, David, Cooney, Julian P, Paul, Sanjoy K and Hill, Geoffrey R. (2021). A phase 3 double-blind study of the addition of tocilizumab versus placebo to cyclosporin/methotrexate GvHD prophylaxis. Blood, 137 (14), 1970-1979. doi: 10.1182/blood.2020009050

A phase 3 double-blind study of the addition of tocilizumab versus placebo to cyclosporin/methotrexate GvHD prophylaxis

2020

Journal Article

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

Montes de Oca, Marcela, de Labastida Rivera, Fabian, Winterford, Clay, Frame, Teija C. M., Ng, Susanna S., Amante, Fiona H., Edwards, Chelsea L., Bukali, Luzia, Wang, Yulin, Uzonna, Jude E., Kuns, Rachel D., Zhang, Ping, Kabat, Agnieszka, Klein Geltink, Ramon I., Pearce, Edward J., Hill, Geoffrey R. and Engwerda, Christian R. (2020). IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection. PLoS Pathogens, 16 (10) e1008994, e1008994. doi: 10.1371/journal.ppat.1008994

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

2020

Journal Article

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Ng, Susanna S., De Labastida Rivera, Fabian, Yan, Juming, Corvino, Dillon, Das, Indrajit, Zhang, Ping, Kuns, Rachel, Chauhan, Shashi Bhushan, Hou, Jiajie, Li, Xian-Yang, Frame, Teija C. M., McEnroe, Benjamin A., Moore, Eilish, Na, Jinrui, Engel, Jessica A., Soon, Megan S. F., Singh, Bhawana, Kueh, Andrew J., Herold, Marco J., Montes de Oca, Marcela, Singh, Siddharth Sankar, Bunn, Patrick T., Aguilera, Amy Roman, Casey, Mika, Braun, Matthias, Ghazanfari, Nazanin, Wani, Shivangi, Wang, Yulin, Amante, Fiona H. ... Engwerda, Christian R. (2020). The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology, 21 (10), 1205-1218. doi: 10.1038/s41590-020-0758-6

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

2020

Journal Article

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

Blazar, Bruce R., Hill, Geoffrey R. and Murphy, William J. (2020). Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD. Nature Reviews Clinical Oncology, 17 (8), 475-492. doi: 10.1038/s41571-020-0356-4

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

2020

Journal Article

Cytokines and costimulation in acute graft-versus-host disease

Hill, Geoffrey R. and Koyama, Motoko (2020). Cytokines and costimulation in acute graft-versus-host disease. Blood, 136 (4), 418-428. doi: 10.1182/blood.2019000952

Cytokines and costimulation in acute graft-versus-host disease

2020

Journal Article

Single-cell transcriptomics of alloreactive CD4+ T cells over time reveals divergent fates during gut graft-versus-host disease

Engel, Jessica A., Lee, Hyun Jae, Williams, Cameron G., Kuns, Rachel, Olver, Stuart, Lansink, Lianne Im, Soon, Megan Sf, Andersen, Stacey B., Powell, Joseph E., Svensson, Valentine, Teichmann, Sarah A., Hill, Geoffrey R., Varelias, Antiopi, Koyama, Motoko and Haque, Ashraful (2020). Single-cell transcriptomics of alloreactive CD4+ T cells over time reveals divergent fates during gut graft-versus-host disease. JCI Insight, 5 (13) 137990, 1-19. doi: 10.1172/jci.insight.137990

Single-cell transcriptomics of alloreactive CD4+ T cells over time reveals divergent fates during gut graft-versus-host disease

2020

Journal Article

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

Cheong, Melody, Gartlan, Kate H., Lee, Jason S., Tey, Siok-Keen, Zhang, Ping, Kuns, Rachel D., Andoniou, Christopher E., Martins, Jose Paulo, Chang, Karshing, Sutton, Vivien R., Kelly, Greg, Varelias, Antiopi, Vuckovic, Slavica, Markey, Kate A., Boyle, Glen M., Smyth, Mark J., Engwerda, Christian R., MacDonald, Kelli P.A., Trapani, Joseph A., Degli-Esposti, Mariapia A., Koyama, Motoko and Hill, Geoffrey R. (2020). ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome. Cancer Immunology Research, 8 (8), 1085-1098. doi: 10.1158/2326-6066.cir-19-0653

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

2020

Journal Article

Experiences and unmet needs of family members requested to donate haematopoietic stem cells to an ill relative: findings from a prospective multi-centre study

Zomerdijk, Nienke, Turner, Jane, Hill, Geoffrey R. and Gottlieb, David (2020). Experiences and unmet needs of family members requested to donate haematopoietic stem cells to an ill relative: findings from a prospective multi-centre study. Supportive Care in Cancer, 29 (2), 635-644. doi: 10.1007/s00520-020-05520-y

Experiences and unmet needs of family members requested to donate haematopoietic stem cells to an ill relative: findings from a prospective multi-centre study

2020

Conference Publication

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

Gartlan, Kate H., Wilkinson, Andrew, Chang, Karshing, Kuns, Rachel D., Henden, Andrea, Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew, Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica and Hill, Geoffrey R. (2020). Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.33

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

2020

Conference Publication

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

Minnie, Simone A., Kuns, Rachel D., Ensbey, Kathleen S., Samson, Luke D., Chesi, Marta, Gartlan, Kate H., Smyth, Mark J., Vuckovic, Slavica and Hill, Geoffrey R. (2020). Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.30

Posttransplant cyclophosphamide as a platform for immunotherapy after allogeneic stem cell transplantation for multiple myeloma

2020

Conference Publication

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

Aguilar, Ethan George, Rhee, Stephanie, Thangavelu, Govindarajan, Loschi, Michael, Paz, Katelyn, Saha, Asim, Ly, Joanna, Sage, Peter, Sharpe, Arlene H., Maillard, Ivan, Murphy, William J., Serody, Jonathan S., Jin, Suji, Wagers, Sara Bolivar, Nicholls, Jemma, Hill, Geoffrey, MacDonald, Kelli P.A., Compeer, Ewoud, Dustin, Michael, O’Connor, Roddy, Sparwasser, Tim and Blazar, Bruce R. (2020). Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD). Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.2

Inhibiting fatty acid synthesis (FAS) can prevent and treat chronic graft versus host disease (cGVHD)

2020

Journal Article

Immunotherapy of multiple myeloma

Minnie, Simone A. and Hill, Geoffrey R. (2020). Immunotherapy of multiple myeloma. The Journal of Clinical Investigation, 130 (4), 1565-1575. doi: 10.1172/JCI129205

Immunotherapy of multiple myeloma

2020

Journal Article

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

Kumar, Rajiv, Bunn, Patrick T., Singh, Siddharth Sankar, Ng, Susanna S., Montes de Oca, Marcela, De Labastida Rivera, Fabian, Chauhan, Shashi Bhushan, Singh, Neetu, Faleiro, Rebecca J., Edwards, Chelsea L., Frame, Teija C.M., Sheel, Meru, Austin, Rebecca J., Lane, Steven W., Bald, Tobias, Smyth, Mark J., Hill, Geoffrey.R., Best, Shannon E., Haque, Ashraful, Corvino, Dillon, Waddell, Nic, Koufariotis, Lambross, Mukhopadhay, Pamela, Rai, Madhukar, Chakravarty, Jaya, Singh, Om Prakash, Sacks, David, Nylen, Susanne, Uzonna, Jude ... Engwerda, Christian R. (2020). Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis. Cell Reports, 30 (8), 2512-2525.e9. doi: 10.1016/j.celrep.2020.01.099

Type I interferons suppress anti-parasitic immunity and can be targeted to improve treatment of visceral leishmaniasis

Current funding

  • 2024 - 2027
    Harnessing the gut microbiome to improve stem cell transplant outcome (NHMRC Ideas 2023 Administered by The Council of the Queensland Institute of Medical Research)
    Queensland Institute of Medical Research
    Open grant

Past funding

  • 2015 - 2016
    Developing new ways to predict infection in patients undergoing chemotherapy and bone marrow transplantation
    UQ Academic Title Holder Research Fund
    Open grant
  • 2010 - 2014
    Immunological therapies for cancer, chronic infection and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2005 - 2009
    Immunological therapies for cancer and autoimmunity
    NHMRC Program Grant
    Open grant
  • 2003 - 2004
    Migration And Differentiation Of Dendritic Cells And Monocytes In Inflammatory Arthritis
    NHMRC Project Grant
    Open grant

Availability

Honorary Professor Geoffrey Hill is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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