Dr Michael Nissen
Dr

Michael Nissen

Email: 

Background

Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.

He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.

Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.

Availability

Dr Michael Nissen is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Research impacts

Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014

Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.

Co-discoverer of WU Virus: 2007

Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).

Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014

Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).

Search Professor Michael Nissen’s works on UQ eSpace

201 works between 1984 and 2023
All (201) Journal Article (176) Book Chapter (5) Conference Publication (18) Other Outputs (2)

101 - 120 of 201 works

2009

Journal Article

Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.

Kugelman, Gayle, Tapsall, John W., Goire, Namraj, Syrmis, Melanie, Limnios, Athena, Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2009). Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.. Antimicrobial Agents & Chemotherapy, 53 (10), 4211-4216. doi: 10.1128/AAC.00385-09

Simple, rapid, and inexpensive detection of Neisseria gonorrhoeae resistance mechanisms using heat-denatured isolates and SYBR green-based real-time PCR.

2009

Journal Article

Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.

Whiley, David M., Goire, Namraj, Ray, E. Sanghamitra, Limnios, Althena, Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Tapsall, John W. (2009). Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.. Sexually Trasmitted Infections, 86 (1), 51-55. doi: 10.1136/sti.2009.037689

Neisseria gonorrhoeae multi-antigen sequence typing using non-cultured clinical specimens.

2009

Journal Article

An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response

Goire, Namraj, Kattenbelt, Jacqueline A., Gould, Allan R., Nissen, Michael D., Sloots, Theo P. and Whiley, David (2009). An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response. Pathology, 41 (6), 607-609. doi: 10.1080/00313020903071488

An example of competitive inhibition in a monoplex real-time PCR as a cause of reduced fluorescent signal response

2009

Journal Article

Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland

Lambert, Stephen B., Faux, Cassandra E., Hall, Lisa, Birrell, F. A., Peterson, K. V., Selvey, C. E., Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2009). Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland. Medical Journal of Australia, 191 (3), 157-160. doi: 10.5694/j.1326-5377.2009.tb02727.x

Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland

2009

Journal Article

Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples

Bialasiewicz, Seweryn, Whiley, David M., Lambert, Stephen B., Nissen, Michael D. and Sloots, Theo P. (2009). Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples. Journal of Clinical Virology, 45 (3), 249-254. doi: 10.1016/j.jcv.2009.05.002

Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples

2009

Journal Article

Detection of novel influenza A(H1N1) virus by real-time RT-PCR.

Whiley, David M., Bialasiewicz, Seweryn, Bletchly, Cheryl, Faux, Cassandra E., Harrower, Bruce, Gould, Allan R., Lambert, Stephen B., Nimmo, Graeme R., Nissen, Michael D. and Sloots, Theo P. (2009). Detection of novel influenza A(H1N1) virus by real-time RT-PCR.. Journal of Clinical Virology, 45 (3), 203-204. doi: 10.1016/j.jcv.2009.05.032

Detection of novel influenza A(H1N1) virus by real-time RT-PCR.

2009

Journal Article

Rotavirus epidemiology in Queensland during the pre-vaccine era.

Campbell, Suzy J., Nissen, Michael D. and Lambert, Stephen B. (2009). Rotavirus epidemiology in Queensland during the pre-vaccine era.. Communicable Diseases Intelligence, 33 (2), 204-208.

Rotavirus epidemiology in Queensland during the pre-vaccine era.

2009

Journal Article

ROTAVIRUS EPIDEMIOLOGY IN QUEENSLAND DURING THE PRE-VACCINE ERA

Campbell, Suzy J., Nissen, Michael D. and Lambert, Stephen B. (2009). ROTAVIRUS EPIDEMIOLOGY IN QUEENSLAND DURING THE PRE-VACCINE ERA. Communicable Diseases Intelligence, 33 (2), 204-208.

ROTAVIRUS EPIDEMIOLOGY IN QUEENSLAND DURING THE PRE-VACCINE ERA

2009

Journal Article

Low rates of Pseudomonas aeruginosa misidentification in isolates from Cystic Fibrosis patients.

Kidd, Timothy J., Ramsay, Kay A., Hu, Honghua Hu, Bye, Peter T. P., Elkins, Mark R., Grimwood, Keith, Harbour, Colin, Marks, Guy B., Nissen, Michael D., Robinson, Phillip J., Rose, Barbara R., Sloots, Theo P., Wainwright, Claire E., Bell, Scott C. and ACPinCF Investigators (2009). Low rates of Pseudomonas aeruginosa misidentification in isolates from Cystic Fibrosis patients.. Journal of Clinical Microbiology, 47 (5), 1503-1509. doi: 10.1128/JCM.00014-09

Low rates of Pseudomonas aeruginosa misidentification in isolates from Cystic Fibrosis patients.

2009

Journal Article

Do rhinoviruses reduce the probability of viral co-detection during acute respiratory tract infections?

Greer, R. M, McErlean, P., Arden, K. E., Faux, C. E., Nitsche, A., Lambert, S. B., Nissen, M. D., Sloots, T. P. and Mackay, I. M. (2009). Do rhinoviruses reduce the probability of viral co-detection during acute respiratory tract infections?. Journal of Clinical Virology, 45 (1), 10-15. doi: 10.1016/j.jcv.2009.03.008

Do rhinoviruses reduce the probability of viral co-detection during acute respiratory tract infections?

2009

Journal Article

A novel gel-based method for self collection and ambient temperature postal transport of urine for PCR detection of Chlamydia trachomatis.

Bialasiewicz, S., Whiley, D. M., Buhrer-Skinner, M., Bautista, C., Barker, K., Aitken, S., Gordon, R., Muller, R., Lambert, S. B., Debattista, J., Nissen, M. D. and Sloots, T. P. (2009). A novel gel-based method for self collection and ambient temperature postal transport of urine for PCR detection of Chlamydia trachomatis.. Sexually Transmitted Infections, 85 (2), 102-105. doi: 10.1136/sti.2008.032607

A novel gel-based method for self collection and ambient temperature postal transport of urine for PCR detection of Chlamydia trachomatis.

2009

Journal Article

Detection of Human Bocavirus in respiratory, fecal and blood samples by real-time PCR

Tozer, Sarah J., Lambert, Stephen B., Whiley, David M., Bialasiewicz, Seweryn, Lyon, Michael J, Nissen, Michael D. and Sloots, Theo P. (2009). Detection of Human Bocavirus in respiratory, fecal and blood samples by real-time PCR. Journal of Medical Virology, 81 (3), 488-493. doi: 10.1002/jmv.21409

Detection of Human Bocavirus in respiratory, fecal and blood samples by real-time PCR

2009

Journal Article

Merkel cell polyomavirus DNA in respiratory specimens from children and adults

Bialasiewicz, Seweryn, Lambert, Stephen B., Whiley, David M., Nissen, Michael D. and Sloots, Theo P. (2009). Merkel cell polyomavirus DNA in respiratory specimens from children and adults. Emerging Infectious Diseases, 15 (3), 492-494. doi: 10.3201/eid1503.081067

Merkel cell polyomavirus DNA in respiratory specimens from children and adults

2009

Journal Article

Identification of Pseudomonas aeruginosa by a duplex real-time polymerase chain reaction assay targeting the ecfX and the gyrB genes

Anuj, Snehal N., Whiley, David M., Kidd, Timothy J., Bell, Scott C., Wainwright, Claire E., Nissen, Michael D. and Sloots, Theo P. (2009). Identification of Pseudomonas aeruginosa by a duplex real-time polymerase chain reaction assay targeting the ecfX and the gyrB genes. Diagnostic Microbiology And Infectious Disease, 63 (2), 127-131. doi: 10.1016/j.diagmicrobio.2008.09.018

Identification of Pseudomonas aeruginosa by a duplex real-time polymerase chain reaction assay targeting the ecfX and the gyrB genes

2009

Conference Publication

Comparison of multilocus sequence typing (MLST), pulse field gel electrophoresis (PFGE), and enterobacterial intergenic consenus PCR (ERIC) for the genotypic analysis of Pseudomonas aeruginosa isolates collected from persons with cystic fibrosis (CF)

Bell, S. C., Grimwood, K., Hargreaves, M., Kidd, T. J., Nissen, M. D., Rainey, P. B., Ramsey, K. A. and Wainwright, C. E. (2009). Comparison of multilocus sequence typing (MLST), pulse field gel electrophoresis (PFGE), and enterobacterial intergenic consenus PCR (ERIC) for the genotypic analysis of Pseudomonas aeruginosa isolates collected from persons with cystic fibrosis (CF). “Cystic Fibrosis – Finding A Balance”, Brisbane, 29 Aug - 1 Sep 2009. not available: not available.

Comparison of multilocus sequence typing (MLST), pulse field gel electrophoresis (PFGE), and enterobacterial intergenic consenus PCR (ERIC) for the genotypic analysis of Pseudomonas aeruginosa isolates collected from persons with cystic fibrosis (CF)

2009

Journal Article

A genome-wide association study identifies novel and functionally related susceptibility loci for Kawasaki Disease

Brugner, David, Davila, Sonia, Breunis, Willemijn B., Ng, Sarah B., Li, Yi, Bonnard, Carine, Ling, Ling, Wright, Victoria J., Thalamuthu, Anbupalam, Odam, Miranda, Shimizu, Chisato, Burns, Jane C., Levin, Michael, Kuijpers, Taco W., Hibberd, Martin L., International Kawasaki Disease Genetics Consortium and Nissen, Michael, D. (2009). A genome-wide association study identifies novel and functionally related susceptibility loci for Kawasaki Disease. PLoS Genetics, January 2009 (1) e1000319, x-x. doi: 10.1371/journal.pgen.1000319

A genome-wide association study identifies novel and functionally related susceptibility loci for Kawasaki Disease

2009

Conference Publication

Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland, Australia

Lambert, Stephen B., Faux, Cassandra E., Hall, L., Birrell, F. E., Peterson, K. V., Selvey, C., Sloots, T. P., Nissen, M. D. and Grimwood, K. (2009). Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland, Australia. European Society for Paediatric Infectious Diseases, 27th Annual Scientic Meeting, Brussels, Belgium, 9-13 June 2009.

Early evidence for direct and indirect effects of the infant rotavirus vaccine program in Queensland, Australia

2008

Journal Article

Pertussis in infants: How to protect the vulnerable?

Chuk, L-m R, Stephen Lambert, May, M.L., Beard, F. H., Sloots, T. P., Selvey, C. E. and Nissen, Michael D. (2008). Pertussis in infants: How to protect the vulnerable?. Communicable Diseases Intelligence, 32 (4), 449-456.

Pertussis in infants: How to protect the vulnerable?

2008

Journal Article

Australian Rotavirus Surveillance Program. Annual Report, 2007/08

Kirkwood, Carl D., Boniface, Karen, Bishop, Ruth F., Barnes, Graeme L. and Nissen, Michael D. (2008). Australian Rotavirus Surveillance Program. Annual Report, 2007/08. Communicable Diseases Intelligence, 32 (4), 425-429.

Australian Rotavirus Surveillance Program. Annual Report, 2007/08

2008

Journal Article

PERTUSSIS IN INFANTS: HOW TO PROTECT THE VULNERABLE?

Chuk, Lai-Man R., Lambert, Stephen B., May, Meryta L., Beard, Frank H., Sloots, Theo P., Selvey, Christine E. and Nissen, Michael D. (2008). PERTUSSIS IN INFANTS: HOW TO PROTECT THE VULNERABLE?. Communicable Diseases Intelligence, 32 (4), 449-456.

PERTUSSIS IN INFANTS: HOW TO PROTECT THE VULNERABLE?

Past funding

  • 2013 - 2016
    Q fever: How common is it and how can we best prevent it? Research to inform Q fever vaccine policy in Australia and Internationally. (NHMRC project grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2010 - 2016
    Molecular microbiology and epidemiology of respiratory infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Characterisation of novel picornavirus-like viruses identified from patients with acute respiratory infections
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Clinical impact of clonal Pseudomonas aeruginosa in cystic fibrosis
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    The clinical and epidemiological characterisation of a newly discovered human polyonmavirus, WU (WU Virus Research)
    Royal Children's Hospital Foundation
    Open grant
  • 2006
    Identification of Virulence Markers in the Respiratory Syncytial Virus Genome
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2006
    Characterisation and Epidemiology of Emerging Pathogens in Paediatrics
    ANZ Executors and Trustees' Company Ltd
    Open grant
  • 2005 - 2010
    Research support for paediatric infectious diseases
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    Epidemiology and Control of Q Fever in Children
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    How Children and adults with cystic fibrosis get lung infections with Pseudomonas aeruginosa
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2010
    (i) Detection of mucoid P. aeruginosa antigens and antibodies in CF (ii) Molecular epidemiology of respiratory syncytial virus infections and the immune response in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2003
    Macquarie Bank Asthma Research Fellowship for 2003
    Royal Australasian College of Physicians
    Open grant
  • 2003 - 2008
    The clinical significance of human metapneumovirus infections in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Molecular epidemiology of respiratory syncitial virus in Australia
    UQ Early Career Researcher
    Open grant
  • 2001
    Establishment of a Malarial & Molecular Research Program at the RCH, Brisbane
    Royal Children's Hospital Foundation
    Open grant
  • 2001
    Real-time diagnosis of respiratory tract infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2000 - 2001
    Establishment of a Paediatric and Molecular Infectious Diseases Research Program at the Royal Children's Hospital, Brisbane
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2000
    Competitive Research Equipment Grant
    Royal Children's Hospital Foundation
    Open grant

Availability

Dr Michael Nissen is:
Available for supervision

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Supervision history

Completed supervision

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