Dr Michael Nissen
Dr

Michael Nissen

Email: 

Background

Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.

He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.

Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.

Availability

Dr Michael Nissen is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Research impacts

Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014

Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.

Co-discoverer of WU Virus: 2007

Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).

Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014

Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).

Search Professor Michael Nissen’s works on UQ eSpace

198 works between 1984 and 2023
All (198) Journal Article (173) Book Chapter (5) Conference Publication (18) Other Outputs (2)

121 - 140 of 198 works

2008

Journal Article

Human metapneumovirus in lung transplant recipients and comparison to respiratory syncytial virus

Hopkins, Peter, McNeil, Keith, Kermeen, Fiona, Musk, Michael, McQueen, Emily, Mackay, Ian, Sloots, Terry and Nissen, Michael (2008). Human metapneumovirus in lung transplant recipients and comparison to respiratory syncytial virus. American Journal of Respiratory and Critical Care Medicine, 178 (8), 876-881. doi: 10.1164/rccm.200711-1657OC

Human metapneumovirus in lung transplant recipients and comparison to respiratory syncytial virus

2008

Journal Article

Identification of Australian human respiratory syncytial virus strains containing a 60-nucleotide duplication within the G glycoprotein gene.

Tozer, S., Whiley, D. M., Lunn, G., Rawlinson, W. D., Sammels, L. M., Sloots, T. P. and Nissen, M. D. (2008). Identification of Australian human respiratory syncytial virus strains containing a 60-nucleotide duplication within the G glycoprotein gene.. Pathology, 40 (6), 632-635. doi: 10.1080/00313020802320655

Identification of Australian human respiratory syncytial virus strains containing a 60-nucleotide duplication within the G glycoprotein gene.

2008

Journal Article

Micafungin versus liposomal amphotericin B for pediatric patients with invasive candidiasis: Substudy of a randomized double-blind trial.

Queiroz-Telles, Flavio, Berezin, Eitan, Leverger, Guy, Freire, Antonio, van der Vyver, Annalie, Chotpitayasunondh, Tawee, Konja, Josip, Diekmann-Berndit, Heike, Koblinger, Sonja, Groll, Andreas H., Arrieta, Antonio and Nissen, Michael D. (Micafungin Invasive Candidiasis Study Group) (2008). Micafungin versus liposomal amphotericin B for pediatric patients with invasive candidiasis: Substudy of a randomized double-blind trial.. The Pediatric Infectious Disease Journal, 27 (9), 820-826. doi: 10.1097/INF.0b013e31817275e6

Micafungin versus liposomal amphotericin B for pediatric patients with invasive candidiasis: Substudy of a randomized double-blind trial.

2008

Journal Article

Comparing nose-throat swabs and nasopharyngeal aspirates collected from children with symptoms for respiratory virus identification using real-time polymerase chain reaction

Lambert, Stephen B., Whiley, David M., O'Neill, Nicholas T., Andrews, Emily C., Canavan, Fiona M., Bletchly, Cheryl, Siebert, David J., Sloots, Theo P. and Nissen, Michael D. (2008). Comparing nose-throat swabs and nasopharyngeal aspirates collected from children with symptoms for respiratory virus identification using real-time polymerase chain reaction. Pediatrics, 122 (3), e615-e620. doi: 10.1542/peds.2008-0691

Comparing nose-throat swabs and nasopharyngeal aspirates collected from children with symptoms for respiratory virus identification using real-time polymerase chain reaction

2008

Journal Article

High prevalence of a class 1 integron-associated aadB gene cassette in Pseudomonas aeruginosa isolates from an Australian cystic fibrosis patient population

Syrmis, Melanie, Bell, Scott, Bye, Peter, Coulter, Chris, Harbour, Colin, Iredell, Jon, Kidd, Tim, O'Carroll, Mark, Rose, Barbara, Wainwright, Claire, Sloots, Theo and Nissen, Michael (2008). High prevalence of a class 1 integron-associated aadB gene cassette in Pseudomonas aeruginosa isolates from an Australian cystic fibrosis patient population. Pathology, 40 (5), 524-525. doi: 10.1080/00313020802197921

High prevalence of a class 1 integron-associated aadB gene cassette in Pseudomonas aeruginosa isolates from an Australian cystic fibrosis patient population

2008

Journal Article

Emerging respiratory agents: New viruses for old diseases?

Sloots, T. P., Whiley, D. M., Lambert, S. B. and Nissen, M. D. (2008). Emerging respiratory agents: New viruses for old diseases?. Journal of Clinical Virology, 42 (3), 233-243. doi: 10.1016/j.jcv.2008.03.002

Emerging respiratory agents: New viruses for old diseases?

2008

Journal Article

False-Negative results in nucleic acid amplification tests: do we need to routinely use two genetic targets in all assays to overcome problems caused by sequence variation?

Whiley, D. M., Lambert, S., Bialasiewicz, S., Goire, N., Nissen, M. D. and Sloots, T. P. (2008). False-Negative results in nucleic acid amplification tests: do we need to routinely use two genetic targets in all assays to overcome problems caused by sequence variation?. Critical Reviews in Microbiology, 34 (2), 71-76. doi: 10.1080/10408410801960913

False-Negative results in nucleic acid amplification tests: do we need to routinely use two genetic targets in all assays to overcome problems caused by sequence variation?

2008

Journal Article

Distinguishing molecular features and clinical characteristics of a putative new rhinovirus species, Human Rhinovirus C (HRV C)

McErlean, Peter, Shackelton, Laura A., Andrews, Emily, Webster, Dale R., Lambert, Stephen B., Nissen, Michael D., Sloots, Theo P. and Mackay, Ian M. (2008). Distinguishing molecular features and clinical characteristics of a putative new rhinovirus species, Human Rhinovirus C (HRV C). PLoS one, 3 (4) e1847, e1847-e1847. doi: 10.1371/journal.pone.0001847

Distinguishing molecular features and clinical characteristics of a putative new rhinovirus species, Human Rhinovirus C (HRV C)

2008

Journal Article

Seroconversion to filarial antigens in Australian defence force personnel in Timor-Leste

Francis, Stephen P., Baade, Lisa M., Kubofoik, Joseph, Nutman, Thomas B., Melrose, Wayne D., McCarthy, James S. and Nissen, Michael D. (2008). Seroconversion to filarial antigens in Australian defence force personnel in Timor-Leste. The American Journal of Tropical Medicine and Hygiene, 78 (4), 560-563. doi: 10.4269/ajtmh.2008.78.560

Seroconversion to filarial antigens in Australian defence force personnel in Timor-Leste

2008

Journal Article

Major histocompatibility complex class I cytotoxic T lymphocyte immunity to human metapneumovirus (hMPV) in individuals with previous hMPV infection and respiratory disease

Herd, K. A., Nissen, M. D., Hopkins, P. M., Sloots, T. P. and Tindle, R. W. (2008). Major histocompatibility complex class I cytotoxic T lymphocyte immunity to human metapneumovirus (hMPV) in individuals with previous hMPV infection and respiratory disease. The Journal of Infectious Diseases, 197 (4), 584-592. doi: 10.1086/526536

Major histocompatibility complex class I cytotoxic T lymphocyte immunity to human metapneumovirus (hMPV) in individuals with previous hMPV infection and respiratory disease

2008

Journal Article

Human metapneumovirus and human coronavirus NL63 - In reply

Lambert, Stephen B., Allen, Kelly M., Sloots, Theo P., Nissen, Michael D. and Nolan, Terry M. (2008). Human metapneumovirus and human coronavirus NL63 - In reply. Pediatrics, 121 (2), 446-447. doi: 10.1542/peds.2007-3386

Human metapneumovirus and human coronavirus NL63 - In reply

2008

Journal Article

Presence of the newly discovered human polyomaviruses KI and WU in Australian patients with acute respiratory tract infection

Bialasiewicz, S., Whiley, D. M., Lambert, S. B., Jacob, K., Bletchly, C., Wang, D., Nissen, M. D. and Sloots, T. P. (2008). Presence of the newly discovered human polyomaviruses KI and WU in Australian patients with acute respiratory tract infection. Journal of Clinical Virology, 41 (2), 63-68. doi: 10.1016/j.jcv.2007.11.001

Presence of the newly discovered human polyomaviruses KI and WU in Australian patients with acute respiratory tract infection

2008

Journal Article

A duplex Neisseria gonorrhoeae real-time polymerase chain reaction assay targeting the gonoccoccal porA pseudogene and multicopy opa genes

Goire, Namraj, Nissen, Michael D., LeCornec, Genevera M., Sloots, Theo P. and Whiley, David, M. (2008). A duplex Neisseria gonorrhoeae real-time polymerase chain reaction assay targeting the gonoccoccal porA pseudogene and multicopy opa genes. Diagnostic Microbiology and Infectious Disease, 61 (1), 6-12. doi: 10.1016/j.diagmicrobio.2007.12.007

A duplex Neisseria gonorrhoeae real-time polymerase chain reaction assay targeting the gonoccoccal porA pseudogene and multicopy opa genes

2007

Journal Article

Development and evaluation of real-time PCR assays for the detection of the newly identified KI and WU polyomaviruses

Bialasiewicz, S., Whiley, D. M., Lambert, S. B., Gould, A., Nissen, M. D. and Sloots, T. P. (2007). Development and evaluation of real-time PCR assays for the detection of the newly identified KI and WU polyomaviruses. Journal of Clinical Virology, 40 (1), 9-14. doi: 10.1016/j.jcv.2007.07.015

Development and evaluation of real-time PCR assays for the detection of the newly identified KI and WU polyomaviruses

2007

Journal Article

A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children

Bialasiewicz, Seweryn, Whiley, David M., Lambert, Stephen B., Wang, David, Nissen, Michael D. and Sloots, Theo P. (2007). A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children. Journal of Clinical Virology, 40 (1), 15-18. doi: 10.1016/j.jcv.2007.07.001

A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children

2007

Journal Article

Congenital and neonatal pneumonia.

Nissen, M. D. (2007). Congenital and neonatal pneumonia.. Paediatric Respiratory Reviews, 8 (3), 195-203. doi: 10.1016/j.prrv.2007.07.00

Congenital and neonatal pneumonia.

2007

Journal Article

Community epidemiology of human Metapneumovirus, human Coronavirus NL63, and other respiratory viruses in healthy preshcool-aged children using parent-collected specimens

Lambert, Stephen B., Allen, Kelly M., Druce, Julian D., Birch, Chris J., Mackay, Ian M., Carlin, John B., Carapetis, Jonathan R., Sloots, Theo P., Nissen, Michael D. and Nolan, Terence M. (2007). Community epidemiology of human Metapneumovirus, human Coronavirus NL63, and other respiratory viruses in healthy preshcool-aged children using parent-collected specimens. Pediatrics, 120 (4), e929-e937. doi: 10.1542/peds.2006-3703

Community epidemiology of human Metapneumovirus, human Coronavirus NL63, and other respiratory viruses in healthy preshcool-aged children using parent-collected specimens

2007

Journal Article

Use of a novel screening PCR indicates presence of Neisseria gonorrhoeae isolates with a mosaic penA gene sequence in Australia

Whiley, David, Bates, John, Limnios, Athena, Nissen, Michael D., Tapsall, John and Sloots, Theo P. (2007). Use of a novel screening PCR indicates presence of Neisseria gonorrhoeae isolates with a mosaic penA gene sequence in Australia. Pathology, 39 (4), 445-446. doi: 10.1080/00313020701444515

Use of a novel screening PCR indicates presence of Neisseria gonorrhoeae isolates with a mosaic penA gene sequence in Australia

2007

Journal Article

Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis

McErlean, P., Shackelton, L. A., Lambert, S. B., Nissen, M. D., Sloots, T. P. and Mackay, I. M. (2007). Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis. Journal of Clinical Virology, 39 (2), 67-75. doi: 10.1016/j.jcv.2007.03.012

Characterisation of a newly identified human rhinovirus, HRV-QPM, discovered in infants with bronchiolitis

2007

Journal Article

Bordetella Pertussis PCR positivity, following onset of illness in chldren under 5 years of age

Palmer, C. M., McCall, B., Jarvinen, K. and Nissen, M. D. (2007). Bordetella Pertussis PCR positivity, following onset of illness in chldren under 5 years of age. Communicable Diseases Intelligence, 31 (2), 202-204.

Bordetella Pertussis PCR positivity, following onset of illness in chldren under 5 years of age

Past funding

  • 2013 - 2016
    Q fever: How common is it and how can we best prevent it? Research to inform Q fever vaccine policy in Australia and Internationally. (NHMRC project grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2010 - 2016
    Molecular microbiology and epidemiology of respiratory infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Characterisation of novel picornavirus-like viruses identified from patients with acute respiratory infections
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Clinical impact of clonal Pseudomonas aeruginosa in cystic fibrosis
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    The clinical and epidemiological characterisation of a newly discovered human polyonmavirus, WU (WU Virus Research)
    Royal Children's Hospital Foundation
    Open grant
  • 2006
    Identification of Virulence Markers in the Respiratory Syncytial Virus Genome
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2006
    Characterisation and Epidemiology of Emerging Pathogens in Paediatrics
    ANZ Executors and Trustees' Company Ltd
    Open grant
  • 2005 - 2010
    Research support for paediatric infectious diseases
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    Epidemiology and Control of Q Fever in Children
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    How Children and adults with cystic fibrosis get lung infections with Pseudomonas aeruginosa
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2010
    (i) Detection of mucoid P. aeruginosa antigens and antibodies in CF (ii) Molecular epidemiology of respiratory syncytial virus infections and the immune response in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2003
    Macquarie Bank Asthma Research Fellowship for 2003
    Royal Australasian College of Physicians
    Open grant
  • 2003 - 2008
    The clinical significance of human metapneumovirus infections in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Molecular epidemiology of respiratory syncitial virus in Australia
    UQ Early Career Researcher
    Open grant
  • 2001
    Establishment of a Malarial & Molecular Research Program at the RCH, Brisbane
    Royal Children's Hospital Foundation
    Open grant
  • 2001
    Real-time diagnosis of respiratory tract infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2000 - 2001
    Establishment of a Paediatric and Molecular Infectious Diseases Research Program at the Royal Children's Hospital, Brisbane
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2000
    Competitive Research Equipment Grant
    Royal Children's Hospital Foundation
    Open grant

Availability

Dr Michael Nissen is:
Available for supervision

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Supervision history

Completed supervision

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