Dr Michael Nissen
Dr

Michael Nissen

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Background

Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.

He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.

Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.

Availability

Dr Michael Nissen is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Research impacts

Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014

Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.

Co-discoverer of WU Virus: 2007

Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).

Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014

Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).

Search Professor Michael Nissen’s works on UQ eSpace

198 works between 1984 and 2023
All (198) Journal Article (173) Book Chapter (5) Conference Publication (18) Other Outputs (2)

141 - 160 of 198 works

2007

Journal Article

Identification of a novel polyomavirus from patients with acute respiratory tract infections

Gaynor, Anne M., Nissen, Michael D., Whiley, David M., Mackay, Ian M., Lambert, Stephen B., Wu, Guang, Brennan, Daniel C., Storch, Gregory A., Sloots, Theo P. and Wang, David (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens, 3 (5 e64) e64, 0595-0604. doi: 10.1371/journal.ppat.0030064

Identification of a novel polyomavirus from patients with acute respiratory tract infections

2007

Journal Article

Impact of competitive inhibition and sequence variation upon the sensitivity of Malaria PCR

Bialasiewicz, Seweryn, Whiley, David M., Nissen, Michael D. and Sloots, Theo P. (2007). Impact of competitive inhibition and sequence variation upon the sensitivity of Malaria PCR. Journal of Clinical Microbiology, 45 (5), 1621-1623. doi: 10.1128/JCM.02145-06

Impact of competitive inhibition and sequence variation upon the sensitivity of Malaria PCR

2007

Journal Article

Flinders Island spotted fever rickettsioses caused by "marmionii" strain of rickettsia honei, Eastern Australia

Unsworth, Nathan B., Stenos, John, Graves, Stephen R., Faa, Antony G., Cox, G. Erika, Dyer, John R., Boutlis, Craig S., Lane, Amanda M., Shaw, Matthew D., Robson, Jennifer and Nissen, Michael D. (2007). Flinders Island spotted fever rickettsioses caused by "marmionii" strain of rickettsia honei, Eastern Australia. Emerging Infectious Diseases, 13 (4), 566-573. doi: 10.3201/eid1304.060087

Flinders Island spotted fever rickettsioses caused by "marmionii" strain of rickettsia honei, Eastern Australia

2007

Journal Article

Impact of meningococcal C conjugate vaccine use in Australia

Booy, Robert, Jeffs, Jane, El Bashir, Haitham and Nissen, Michael D. (2007). Impact of meningococcal C conjugate vaccine use in Australia. Medical Journal of Australia, 186 (3), 108-109.

Impact of meningococcal C conjugate vaccine use in Australia

2007

Conference Publication

The impact of oligonucleotide design on PCR sensitivity. Abstract M-54

Bialasiewicz S., Whiley D., Nissen, M. D. and Sloots, T. P. (2007). The impact of oligonucleotide design on PCR sensitivity. Abstract M-54. Clinical Virology Symposium, Clearwater, FL, USA, 2007.

The impact of oligonucleotide design on PCR sensitivity. Abstract M-54

2007

Conference Publication

The impact of quasispecies on respiratory virus PCR.

Mackay, I. M., McErlean, P., Nissen, M. D. and Sloots, T. P. (2007). The impact of quasispecies on respiratory virus PCR.. IX International Symposium on Respiratory Viral Infections Abstract P20., Hong Kong, March 2007.

The impact of quasispecies on respiratory virus PCR.

2007

Book Chapter

Real-time PCR; History and Fluorgenic Chemistries

Mackay, I. M., Mackay, J. F., Nissen, M. D. and Sloots, T. P. (2007). Real-time PCR; History and Fluorgenic Chemistries. Real-Time PCR in Microbiology From diagnosis to characterization. (pp. 1-40) edited by Mackay, I. M.. United Kingdom: Horizon Press - Calister Academic Press.

Real-time PCR; History and Fluorgenic Chemistries

2007

Journal Article

Incidence, etiology, and symptomatology of upper respiratory illness in elite athletes

Spence, Luke, Brown, Wendy J., Pyne, David B., Nissen, Michael D., Sloots, Theo P., McCormack, Joseph G., Locke, A. Simon and Fricker, Peter A. (2007). Incidence, etiology, and symptomatology of upper respiratory illness in elite athletes. Medicine and Science in Sports and Exercise, 39 (4), 577-586. doi: 10.1249/mss.0b013e31802e851a

Incidence, etiology, and symptomatology of upper respiratory illness in elite athletes

2007

Book Chapter

Challenges Facing Real-time PCR Characterization of Acute Respiratory Tract Infections.

Mackay, I. M., Arden, K. E., Nissen, M. D. and Sloots, T. P. (2007). Challenges Facing Real-time PCR Characterization of Acute Respiratory Tract Infections.. Real-Time PCR in Microbiology from Diagnosis to Characterization.. (pp. 269-318) edited by Mackay, I.M.. United Kingdom: Horizon Press - Calister Academic Press.

Challenges Facing Real-time PCR Characterization of Acute Respiratory Tract Infections.

2006

Journal Article

Case for varicella surveillance in Australia

Peadon, Elizabeth, Burgner, David, Nissen, Michael, Buttery, Jim, Zurynski, Yvonne, Elliott, Elizabeth, Gold, Michael, Marshall, Helen and Booy, Robert (2006). Case for varicella surveillance in Australia. Journal of Paediatrics and Child Health, 42 (11), 663-664. doi: 10.1111/j.1440-1754.2006.00949.x

Case for varicella surveillance in Australia

2006

Journal Article

Human coronavirus nomenclature

Lambert, Stephen, Mackay, Ian M., Sloots, Theo P. and Nissen, Michael D. (2006). Human coronavirus nomenclature. Pediatric Infectious Disease Journal, 25 (7), 662-662. doi: 10.1097/01.inf.0000225784.06712.8e

Human coronavirus nomenclature

2006

Journal Article

Genetic diversity of human metapneumovirus over 4 consecutive years in Australia

Mackay, Ian M., Bialasiewicz, Seweryn, Jacob, Kevin C., McQueen, Emily, Arden, Katherine E., Nissen, Michael D. and Sloots, Theo P. (2006). Genetic diversity of human metapneumovirus over 4 consecutive years in Australia. Journal of Infectious Diseases, 193 (12), 1630-1633. doi: 10.1086/504260

Genetic diversity of human metapneumovirus over 4 consecutive years in Australia

2006

Journal Article

Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice

Herd, Karen A., Mahalingam, Suresh, Mackay, Ian M., Nissen, Michael, Sloots, Theo P. and Tindle, Robert W. (2006). Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. Journal of Virology, 80 (4), 2034-2044. doi: 10.1128/JVI.80.4.2034-2044.2006

Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice

2006

Journal Article

Evidence that the gonococcal porA pseudogene is present in a broad range of Neisseria gonorrhoeae strains; suitability as a diagnostic target

Whiley, David M., Anderson, Trevor P., Barratt, Kevin, Beaman, Miles H., Buda, Philip J., Carter, Martine, Freeman, Kevin, Hallsworth, Peter, Limnios, E. Athena, Lum, Gary, Merien, Fabrice, Vernel-Pauillac, Frédérique, Tapsall, John W., Witt, Michael J., Nissen, Michael D. and Sloots, Theo P. (2006). Evidence that the gonococcal porA pseudogene is present in a broad range of Neisseria gonorrhoeae strains; suitability as a diagnostic target. Pathology, 38 (5), 445-448. doi: 10.1080/00313020600928253

Evidence that the gonococcal porA pseudogene is present in a broad range of Neisseria gonorrhoeae strains; suitability as a diagnostic target

2006

Journal Article

Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?

Mahalingam, S., Schwarze, J., Zaid, A., Nissen, M., Sloots, T., Tauro, S., Storer, J., Alvarez, R. and Tripp, R. A. (2006). Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?. Microbes And Infection, 8 (1), 285-293. doi: 10.1016/j.micinf.2005.07.001

Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?

2006

Conference Publication

A four year study of human metapneumovirus in Australia

Sloots, T. P., Mackay, I. M., Jacob, K.C., Bialasiewicz, S. and Nissen, M. D. (2006). A four year study of human metapneumovirus in Australia. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Australia,, 2-6 July 2006.

A four year study of human metapneumovirus in Australia

2006

Journal Article

Human metapneumovirus, Australia, 2001-2004

Sloots, T. P., Mackay, I. M., Bialasiewicz, S., Jacob, K. C., McQueen, E., Harnett, G. B., Siebert, D. J., Masters, I. B., Young, P. R. and Nissen, M. D. (2006). Human metapneumovirus, Australia, 2001-2004. Emerging Infectious Diseases, 12 (8), 1263-1266. doi: 10.3201/eid1708.051239

Human metapneumovirus, Australia, 2001-2004

2006

Journal Article

Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

Arden, Katherine E., McErlean, Peter, Nissen, Michael D, Sloots, Theo P. and Mackay, Ian M. (2006). Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. Journal of Medical Virology, 78 (9), 1232-1240. doi: 10.1002/jmv.20689

Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

2006

Conference Publication

Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection

Sloots, T. P., McErlean, P., Speicher D. J., Arden, K., Nissen, M. D. and Mackay, I.M. (2006). Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Australia, 2006.

Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection

2006

Conference Publication

Factors influencing the sensitivity of the malarial PCR assay.

Bialasiewicz S., Whiley D., Nissen, M. D. and Sloots, T. P. (2006). Factors influencing the sensitivity of the malarial PCR assay.. ASM SVM Special Interest Group Meeting, Brisbane, 2006.

Factors influencing the sensitivity of the malarial PCR assay.

Past funding

  • 2013 - 2016
    Q fever: How common is it and how can we best prevent it? Research to inform Q fever vaccine policy in Australia and Internationally. (NHMRC project grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2010 - 2016
    Molecular microbiology and epidemiology of respiratory infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Characterisation of novel picornavirus-like viruses identified from patients with acute respiratory infections
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Clinical impact of clonal Pseudomonas aeruginosa in cystic fibrosis
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    The clinical and epidemiological characterisation of a newly discovered human polyonmavirus, WU (WU Virus Research)
    Royal Children's Hospital Foundation
    Open grant
  • 2006
    Identification of Virulence Markers in the Respiratory Syncytial Virus Genome
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2006
    Characterisation and Epidemiology of Emerging Pathogens in Paediatrics
    ANZ Executors and Trustees' Company Ltd
    Open grant
  • 2005 - 2010
    Research support for paediatric infectious diseases
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    Epidemiology and Control of Q Fever in Children
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    How Children and adults with cystic fibrosis get lung infections with Pseudomonas aeruginosa
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2010
    (i) Detection of mucoid P. aeruginosa antigens and antibodies in CF (ii) Molecular epidemiology of respiratory syncytial virus infections and the immune response in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2003
    Macquarie Bank Asthma Research Fellowship for 2003
    Royal Australasian College of Physicians
    Open grant
  • 2003 - 2008
    The clinical significance of human metapneumovirus infections in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Molecular epidemiology of respiratory syncitial virus in Australia
    UQ Early Career Researcher
    Open grant
  • 2001
    Establishment of a Malarial & Molecular Research Program at the RCH, Brisbane
    Royal Children's Hospital Foundation
    Open grant
  • 2001
    Real-time diagnosis of respiratory tract infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2000 - 2001
    Establishment of a Paediatric and Molecular Infectious Diseases Research Program at the Royal Children's Hospital, Brisbane
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2000
    Competitive Research Equipment Grant
    Royal Children's Hospital Foundation
    Open grant

Availability

Dr Michael Nissen is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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