Dr Michael Nissen
Dr

Michael Nissen

Email: 

Background

Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.

He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.

Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.

Availability

Dr Michael Nissen is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Research impacts

Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014

Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.

Co-discoverer of WU Virus: 2007

Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).

Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014

Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).

Search Professor Michael Nissen’s works on UQ eSpace

198 works between 1984 and 2023
All (198) Journal Article (173) Book Chapter (5) Conference Publication (18) Other Outputs (2)

1 - 20 of 198 works

2023

Journal Article

The clinicopathological features of thrombosis with thrombocytopenia syndrome following ChAdOx1-S (AZD1222) vaccination and case outcomes in Australia: a population-based study

Tran, Huyen A., Deng, Lucy, Wood, Nicholas, Choi, Philip, Singleton, Sally, Clarke, Lisa, Khanlari, Sarah, Maitland-Scott, Isis, Bird, Robert, Brown, Scott, Manoharan, Bavahuna, Tan, Chee Wee, Gold, Michael, Hissaria, Pravin, Melody, Shannon, Chunilal S, Sanjeev D., Buttery, Jim, Clothier, Hazel, Crawford, Nigel W., Phuong, Linny, Pepperell, Dominic, Effler, Paul, Parker, Claire, Carter, Nicola, Macartney, Kristine, McStea, Megan, Miller, Todd, Nissen, Michael, Larter, Claire ... Chen, Vivien M. (2023). The clinicopathological features of thrombosis with thrombocytopenia syndrome following ChAdOx1-S (AZD1222) vaccination and case outcomes in Australia: a population-based study. The Lancet Regional Health - Western Pacific, 40 100894, 100894. doi: 10.1016/j.lanwpc.2023.100894

The clinicopathological features of thrombosis with thrombocytopenia syndrome following ChAdOx1-S (AZD1222) vaccination and case outcomes in Australia: a population-based study

2022

Journal Article

Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged < 2 Years (vol 11, pg 199, 2022)

Mihala, Gabor, Ware, Robert S., Lambert, Stephen B., Bialasiewicz, Seweryn, Whiley, David M., Sarna, Mohinder, Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2022). Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged < 2 Years (vol 11, pg 199, 2022). Journal of the Pediatric Infectious Diseases Society, 11 (8), 388-388. doi: 10.1093/jpids/piac075

Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged < 2 Years (vol 11, pg 199, 2022)

2022

Journal Article

The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook

George, C.R. Robert, Booy, Robert, Nissen, Michael D. and Lahra, Monica M. (2022). The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook. Medical Journal of Australia, 216 (10), 504-507. doi: 10.5694/mja2.51463

The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook

2022

Journal Article

Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing Otitis Media are diversely distributed

Ngo, Chinh C., Massa, Helen M., McMonagle, Brent A., Perry, Christopher F., Nissen, Michael D., Sloots, Theo P., Thornton, Ruth B. and Cripps, Allan W. (2022). Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing Otitis Media are diversely distributed. Frontiers in Cellular and Infection Microbiology, 12 775535, 775535. doi: 10.3389/fcimb.2022.775535

Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing Otitis Media are diversely distributed

2022

Journal Article

Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged <2 Years

Mihala, Gabor, Ware, Robert S., Lambert, Stephen B., Bialasiewicz, Seweryn, Whiley, David M., Sarna, Mohinder, Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2022). Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged <2 Years. Journal of the Pediatric Infectious Diseases Society, 11 (5), 199-206. doi: 10.1093/jpids/piab130

Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged <2 Years

2021

Journal Article

The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region

Hoe Nam, Leong, Chiu, Cheng-Hsun, Heo, Jung Yeon, Ip, Margaret, Jung, Ki-Suck, Menzies, Robert, Pearce, Rodney, Buchy, Philippe, Chen, Jing, Nissen, Michael and Oh, Kyu-Bin (2021). The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region. Expert Review of Vaccines, 20 (12), 1603-1617. doi: 10.1080/14760584.2021.1990759

The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region

2021

Journal Article

COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control

Buchy, Philippe, Buisson, Yves, Cintra, Otavio, Dwyer, Dominic E., Nissen, Michael, Ortiz de Lejarazu, Raul and Petersen, Eskild (2021). COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control. International Journal of Infectious Diseases, 112, 300-317. doi: 10.1016/j.ijid.2021.09.045

COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control

2020

Journal Article

Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis

Bayliss, Julianne, Randhawa, Roshnee, Oh, Kyu-Bin, Kandeil, Walid, Jenkins, Victoria A., Turriani, Elisa and Nissen, Michael (2020). Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis. Human Vaccines & Immunotherapeutics, 17 (2), 344-350. doi: 10.1080/21645515.2020.1780848

Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis

2020

Journal Article

Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine

Bayliss, Julianne, Nissen, Michael, Prakash, Damita, Richmond, Peter, Oh, Kyu-Bin and Nolan, Terry (2020). Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine. Human Vaccines & Immunotherapeutics, 17 (1), 176-190. doi: 10.1080/21645515.2020.1764826

Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine

2020

Journal Article

The improving state of Q fever surveillance. A review of Queensland notifications, 2003-2017

Tozer, Sarah, Wood, Caitlin, Si, Damin, Nissen, Michael, Sloots, Theo and Lambert, Stephen (2020). The improving state of Q fever surveillance. A review of Queensland notifications, 2003-2017. Communicable Diseases Intelligence, 44. doi: 10.33321/cdi.2020.44.48

The improving state of Q fever surveillance. A review of Queensland notifications, 2003-2017

2020

Journal Article

Impact of vaccines on antimicrobial resistance

Buchy, Philippe, Ascioglu, Sibel, Buisson, Yves, Datta, Sanjoy, Nissen, Michael, Tambyah, Paul Anantharajah and Vong, Sirenda (2020). Impact of vaccines on antimicrobial resistance. International Journal of Infectious Diseases, 90, 188-196. doi: 10.1016/j.ijid.2019.10.005

Impact of vaccines on antimicrobial resistance

2019

Journal Article

Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?

Nissen, Michael D., Lau, Esther T. L., Cabot, Peter J. and Steadman, Kathryn J. (2019). Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?. BMC Complementary and Alternative Medicine, 19 (1) 162, 162. doi: 10.1186/s12906-019-2574-9

Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?

2019

Journal Article

Nasal swab bacteriology by PCR during the first 24-months of life: a prospective birth cohort study

Palmu, Arto A., Ware, Robert S., Lambert, Stephen B., Sarna, Mohinder, Bialasiewicz, Seweryn, Seib, Kate L., Atack, John M., Nissen, Michael D. and Grimwood, Keith (2019). Nasal swab bacteriology by PCR during the first 24-months of life: a prospective birth cohort study. Pediatric Pulmonology, 54 (3), 289-296. doi: 10.1002/ppul.24231

Nasal swab bacteriology by PCR during the first 24-months of life: a prospective birth cohort study

2019

Journal Article

Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program

Quinn, Helen E., Gidding, Heather F., Marshall, Helen S., Booy, Robert, Elliott, Elizabeth J., Richmond, Peter, Crawford, Nigel, McIntyrean, Peter B., Macartney, Kristine K., Blyth, C., Britton, P., Buttery, J., Clark, J. E., Connell, J., Dale, R., Deverell, M., Dougherty, S., Finucane, C., Gibson, M., Gold, M., Heath, C., Hickie, L., Hutchinson, T., Jones, C., Jones, J., Kent, J., Knight, H., Kynaston, A., Lee, D. ... Zurynski, Y. (2019). Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program. Journal of Infection, 78 (3), 220-225. doi: 10.1016/j.jinf.2018.11.009

Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program

2018

Journal Article

Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia

Kerage, Daniel, Soon, Megan S. F., Doff, Brianna L., Kobayashi, Takumi, Nissen, Michael D., Lam, Pui Yeng, Leggatt, Graham R. and Mattarollo, Stephen R. (2018). Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia. OncoImmunology, 7 (10) e1486952, 1-10. doi: 10.1080/2162402x.2018.1486952

Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia

2017

Journal Article

Viruses causing lower respiratory symptoms in young children: findings from the ORChID birth cohort

Sarna, Mohinder, Lambert, Stephen B., Sloots, Theo P., Whiley, David M., Alsaleh, Asma, Mhango, Lebogang, Bialasiewicz, Seweryn, Wang, David, Nissen, Michael D., Grimwood, Keith and Ware, Robert S. (2017). Viruses causing lower respiratory symptoms in young children: findings from the ORChID birth cohort. Thorax, 73 (10), thoraxjnl-2017. doi: 10.1136/thoraxjnl-2017-210233

Viruses causing lower respiratory symptoms in young children: findings from the ORChID birth cohort

2017

Other Outputs

The impact of β-adrenergic signalling on immune function and immunotherapy in lymphoma

Nissen, Michael (2017). The impact of β-adrenergic signalling on immune function and immunotherapy in lymphoma. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2018.21

The impact of β-adrenergic signalling on immune function and immunotherapy in lymphoma

2017

Journal Article

Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study

Sarna, Mohinder, Ware, Robert S., Lambert, Stephen B., Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2017). Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study. The Journal of Infectious Diseases, 217 (3), 418-427. doi: 10.1093/infdis/jix599

Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study

2017

Journal Article

Invariant natural killer T cell in immune regulation of blood cancers: harnessing their potential in immunotherapies

Lam, Pui Yeng, Nissen, Michael D. and Mattarollo, Stephen R. (2017). Invariant natural killer T cell in immune regulation of blood cancers: harnessing their potential in immunotherapies. Frontiers in Immunology, 8 (OCT) 1355, 1355. doi: 10.3389/fimmu.2017.01355

Invariant natural killer T cell in immune regulation of blood cancers: harnessing their potential in immunotherapies

2016

Journal Article

The burden of community-managed acute respiratory infections in the first 2-years of life

Sarna, Mohinder, Ware, Robert S., Sloots, Theo, Nissen, Michael, Grimwood, Keith and Lambert, Stephen (2016). The burden of community-managed acute respiratory infections in the first 2-years of life. Pediatric Pulmonology, 51 (12), 1336-1346. doi: 10.1002/ppul.23480

The burden of community-managed acute respiratory infections in the first 2-years of life

Past funding

  • 2013 - 2016
    Q fever: How common is it and how can we best prevent it? Research to inform Q fever vaccine policy in Australia and Internationally. (NHMRC project grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2010 - 2016
    Molecular microbiology and epidemiology of respiratory infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Characterisation of novel picornavirus-like viruses identified from patients with acute respiratory infections
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Clinical impact of clonal Pseudomonas aeruginosa in cystic fibrosis
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    The clinical and epidemiological characterisation of a newly discovered human polyonmavirus, WU (WU Virus Research)
    Royal Children's Hospital Foundation
    Open grant
  • 2006
    Identification of Virulence Markers in the Respiratory Syncytial Virus Genome
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2006
    Characterisation and Epidemiology of Emerging Pathogens in Paediatrics
    ANZ Executors and Trustees' Company Ltd
    Open grant
  • 2005 - 2010
    Research support for paediatric infectious diseases
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    Epidemiology and Control of Q Fever in Children
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    How Children and adults with cystic fibrosis get lung infections with Pseudomonas aeruginosa
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2010
    (i) Detection of mucoid P. aeruginosa antigens and antibodies in CF (ii) Molecular epidemiology of respiratory syncytial virus infections and the immune response in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2003
    Macquarie Bank Asthma Research Fellowship for 2003
    Royal Australasian College of Physicians
    Open grant
  • 2003 - 2008
    The clinical significance of human metapneumovirus infections in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Molecular epidemiology of respiratory syncitial virus in Australia
    UQ Early Career Researcher
    Open grant
  • 2001
    Establishment of a Malarial & Molecular Research Program at the RCH, Brisbane
    Royal Children's Hospital Foundation
    Open grant
  • 2001
    Real-time diagnosis of respiratory tract infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2000 - 2001
    Establishment of a Paediatric and Molecular Infectious Diseases Research Program at the Royal Children's Hospital, Brisbane
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2000
    Competitive Research Equipment Grant
    Royal Children's Hospital Foundation
    Open grant

Availability

Dr Michael Nissen is:
Available for supervision

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Supervision history

Completed supervision

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