![Dr Michael Nissen](/sites/default/files/profiles/6931.jpeg)
Overview
Background
Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.
He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.
Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.
Availability
- Dr Michael Nissen is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
Research impacts
Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014
Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.
Co-discoverer of WU Virus: 2007
Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).
Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014
Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).
Works
Search Professor Michael Nissen’s works on UQ eSpace
2023
Journal Article
The clinicopathological features of thrombosis with thrombocytopenia syndrome following ChAdOx1-S (AZD1222) vaccination and case outcomes in Australia: a population-based study
Tran, Huyen A., Deng, Lucy, Wood, Nicholas, Choi, Philip, Singleton, Sally, Clarke, Lisa, Khanlari, Sarah, Maitland-Scott, Isis, Bird, Robert, Brown, Scott, Manoharan, Bavahuna, Tan, Chee Wee, Gold, Michael, Hissaria, Pravin, Melody, Shannon, Chunilal S, Sanjeev D., Buttery, Jim, Clothier, Hazel, Crawford, Nigel W., Phuong, Linny, Pepperell, Dominic, Effler, Paul, Parker, Claire, Carter, Nicola, Macartney, Kristine, McStea, Megan, Miller, Todd, Nissen, Michael, Larter, Claire ... Chen, Vivien M. (2023). The clinicopathological features of thrombosis with thrombocytopenia syndrome following ChAdOx1-S (AZD1222) vaccination and case outcomes in Australia: a population-based study. The Lancet Regional Health - Western Pacific, 40 100894, 100894. doi: 10.1016/j.lanwpc.2023.100894
2022
Journal Article
Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged < 2 Years (vol 11, pg 199, 2022)
Mihala, Gabor, Ware, Robert S., Lambert, Stephen B., Bialasiewicz, Seweryn, Whiley, David M., Sarna, Mohinder, Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2022). Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged < 2 Years (vol 11, pg 199, 2022). Journal of the Pediatric Infectious Diseases Society, 11 (8), 388-388. doi: 10.1093/jpids/piac075
2022
Journal Article
The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook
George, C.R. Robert, Booy, Robert, Nissen, Michael D. and Lahra, Monica M. (2022). The decline of invasive meningococcal disease and influenza in the time of COVID-19: the silver linings of the pandemic playbook. Medical Journal of Australia, 216 (10), 504-507. doi: 10.5694/mja2.51463
2022
Journal Article
Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing Otitis Media are diversely distributed
Ngo, Chinh C., Massa, Helen M., McMonagle, Brent A., Perry, Christopher F., Nissen, Michael D., Sloots, Theo P., Thornton, Ruth B. and Cripps, Allan W. (2022). Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing Otitis Media are diversely distributed. Frontiers in Cellular and Infection Microbiology, 12 775535, 775535. doi: 10.3389/fcimb.2022.775535
2022
Journal Article
Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged <2 Years
Mihala, Gabor, Ware, Robert S., Lambert, Stephen B., Bialasiewicz, Seweryn, Whiley, David M., Sarna, Mohinder, Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2022). Potentially Pathogenic Organisms in Stools and Their Association With Acute Diarrheal Illness in Children Aged <2 Years. Journal of the Pediatric Infectious Diseases Society, 11 (5), 199-206. doi: 10.1093/jpids/piab130
2021
Journal Article
The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region
Hoe Nam, Leong, Chiu, Cheng-Hsun, Heo, Jung Yeon, Ip, Margaret, Jung, Ki-Suck, Menzies, Robert, Pearce, Rodney, Buchy, Philippe, Chen, Jing, Nissen, Michael and Oh, Kyu-Bin (2021). The need for pertussis vaccination among older adults and high-risk groups: a perspective from advanced economies of the Asia Pacific region. Expert Review of Vaccines, 20 (12), 1603-1617. doi: 10.1080/14760584.2021.1990759
2021
Journal Article
COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control
Buchy, Philippe, Buisson, Yves, Cintra, Otavio, Dwyer, Dominic E., Nissen, Michael, Ortiz de Lejarazu, Raul and Petersen, Eskild (2021). COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control. International Journal of Infectious Diseases, 112, 300-317. doi: 10.1016/j.ijid.2021.09.045
2020
Journal Article
Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis
Bayliss, Julianne, Randhawa, Roshnee, Oh, Kyu-Bin, Kandeil, Walid, Jenkins, Victoria A., Turriani, Elisa and Nissen, Michael (2020). Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis. Human Vaccines & Immunotherapeutics, 17 (2), 344-350. doi: 10.1080/21645515.2020.1780848
2020
Journal Article
Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine
Bayliss, Julianne, Nissen, Michael, Prakash, Damita, Richmond, Peter, Oh, Kyu-Bin and Nolan, Terry (2020). Control of vaccine preventable diseases in Australian infants: reviewing a decade of experience with DTPa-HBV-IPV/Hib vaccine. Human Vaccines & Immunotherapeutics, 17 (1), 176-190. doi: 10.1080/21645515.2020.1764826
2020
Journal Article
The improving state of Q fever surveillance. A review of Queensland notifications, 2003-2017
Tozer, Sarah, Wood, Caitlin, Si, Damin, Nissen, Michael, Sloots, Theo and Lambert, Stephen (2020). The improving state of Q fever surveillance. A review of Queensland notifications, 2003-2017. Communicable Diseases Intelligence, 44. doi: 10.33321/cdi.2020.44.48
2020
Journal Article
Impact of vaccines on antimicrobial resistance
Buchy, Philippe, Ascioglu, Sibel, Buisson, Yves, Datta, Sanjoy, Nissen, Michael, Tambyah, Paul Anantharajah and Vong, Sirenda (2020). Impact of vaccines on antimicrobial resistance. International Journal of Infectious Diseases, 90, 188-196. doi: 10.1016/j.ijid.2019.10.005
2019
Journal Article
Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?
Nissen, Michael D., Lau, Esther T. L., Cabot, Peter J. and Steadman, Kathryn J. (2019). Baltic amber teething necklaces: could succinic acid leaching from beads provide anti-inflammatory effects?. BMC Complementary and Alternative Medicine, 19 (1) 162, 162. doi: 10.1186/s12906-019-2574-9
2019
Journal Article
Nasal swab bacteriology by PCR during the first 24-months of life: a prospective birth cohort study
Palmu, Arto A., Ware, Robert S., Lambert, Stephen B., Sarna, Mohinder, Bialasiewicz, Seweryn, Seib, Kate L., Atack, John M., Nissen, Michael D. and Grimwood, Keith (2019). Nasal swab bacteriology by PCR during the first 24-months of life: a prospective birth cohort study. Pediatric Pulmonology, 54 (3), 289-296. doi: 10.1002/ppul.24231
2019
Journal Article
Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program
Quinn, Helen E., Gidding, Heather F., Marshall, Helen S., Booy, Robert, Elliott, Elizabeth J., Richmond, Peter, Crawford, Nigel, McIntyrean, Peter B., Macartney, Kristine K., Blyth, C., Britton, P., Buttery, J., Clark, J. E., Connell, J., Dale, R., Deverell, M., Dougherty, S., Finucane, C., Gibson, M., Gold, M., Heath, C., Hickie, L., Hutchinson, T., Jones, C., Jones, J., Kent, J., Knight, H., Kynaston, A., Lee, D. ... Zurynski, Y. (2019). Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program. Journal of Infection, 78 (3), 220-225. doi: 10.1016/j.jinf.2018.11.009
2018
Journal Article
Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia
Kerage, Daniel, Soon, Megan S. F., Doff, Brianna L., Kobayashi, Takumi, Nissen, Michael D., Lam, Pui Yeng, Leggatt, Graham R. and Mattarollo, Stephen R. (2018). Therapeutic vaccination with 4–1BB co-stimulation eradicates mouse acute myeloid leukemia. OncoImmunology, 7 (10) e1486952, 1-10. doi: 10.1080/2162402x.2018.1486952
2017
Journal Article
Viruses causing lower respiratory symptoms in young children: findings from the ORChID birth cohort
Sarna, Mohinder, Lambert, Stephen B., Sloots, Theo P., Whiley, David M., Alsaleh, Asma, Mhango, Lebogang, Bialasiewicz, Seweryn, Wang, David, Nissen, Michael D., Grimwood, Keith and Ware, Robert S. (2017). Viruses causing lower respiratory symptoms in young children: findings from the ORChID birth cohort. Thorax, 73 (10), thoraxjnl-2017. doi: 10.1136/thoraxjnl-2017-210233
2017
Other Outputs
The impact of β-adrenergic signalling on immune function and immunotherapy in lymphoma
Nissen, Michael (2017). The impact of β-adrenergic signalling on immune function and immunotherapy in lymphoma. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2018.21
2017
Journal Article
Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study
Sarna, Mohinder, Ware, Robert S., Lambert, Stephen B., Sloots, Theo P., Nissen, Michael D. and Grimwood, Keith (2017). Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study. The Journal of Infectious Diseases, 217 (3), 418-427. doi: 10.1093/infdis/jix599
2017
Journal Article
Invariant natural killer T cell in immune regulation of blood cancers: harnessing their potential in immunotherapies
Lam, Pui Yeng, Nissen, Michael D. and Mattarollo, Stephen R. (2017). Invariant natural killer T cell in immune regulation of blood cancers: harnessing their potential in immunotherapies. Frontiers in Immunology, 8 (OCT) 1355, 1355. doi: 10.3389/fimmu.2017.01355
2016
Journal Article
The burden of community-managed acute respiratory infections in the first 2-years of life
Sarna, Mohinder, Ware, Robert S., Sloots, Theo, Nissen, Michael, Grimwood, Keith and Lambert, Stephen (2016). The burden of community-managed acute respiratory infections in the first 2-years of life. Pediatric Pulmonology, 51 (12), 1336-1346. doi: 10.1002/ppul.23480
Funding
Supervision
Availability
- Dr Michael Nissen is:
- Available for supervision
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Supervision history
Completed supervision
-
2013
Doctor Philosophy
Molecular Characterisation and Detection of Gonococcal Antimicrobial Resistance.
Principal Advisor
Other advisors: Associate Professor David Whiley
-
2010
Doctor Philosophy
Clinical and virological characteristics of human metapneumovirus
Principal Advisor
-
2005
Doctor Philosophy
RESPIRATORY DISEASES IN PATIENTS WITH CYSTIC FIBROSIS: ROLE AND PATHOGENESIS OF PSEUDOMONAS AERUGINOSA INFECTION
Principal Advisor
-
2003
Doctor Philosophy
REAL-TIME DETECTION, DIFFERENTIATION AND QUANTITATION OF CLINICALLY RELEVANT VIRUSES
Principal Advisor
-
2010
Doctor Philosophy
Characterisation of Newly Discovered Human Polyomaviruses WU and KI
Joint Principal Advisor
-
2016
Doctor Philosophy
A nationwide study of Neisseria gonorrhoeae antimicrobial resistance; towards molecular AMR surveillance
Associate Advisor
Other advisors: Associate Professor David Whiley
-
2015
Doctor Philosophy
Epidemiology, Diagnosis and Prevention of Q fever in Queensland.
Associate Advisor
-
2015
Doctor Philosophy
Characterising the Pathogenesis and Biology of Newly Described Human Polyomaviruses
Associate Advisor
Other advisors: Associate Professor David Whiley, Dr Seweryn Bialasiewicz
-
2013
Doctor Philosophy
Detection, Identification and Genotyping of Pseudomonas aeruginosa strains isolated from environmental and clinical samples.
Associate Advisor
Other advisors: Associate Professor David Whiley
-
2011
Doctor Philosophy
Ribozymes as Antivirals for Respiratory Syncytial Virus
Associate Advisor
Other advisors: Professor Paul Young
-
2008
Doctor Philosophy
Factors Affecting Nucleic Acid Amplification Tests for Neisseria Gonorrhoeae
Associate Advisor
Media
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