![Dr Michael Nissen](/sites/default/files/profiles/6931.jpeg)
Overview
Background
Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.
He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.
Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.
Availability
- Dr Michael Nissen is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
Research impacts
Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014
Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.
Co-discoverer of WU Virus: 2007
Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).
Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014
Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).
Works
Search Professor Michael Nissen’s works on UQ eSpace
2016
Journal Article
Prospective clinical trial of hepatitis B vaccination in adults with and without type-2 diabetes mellitus
Van Der Meeren, Olivier, Peterson, James T., Dionne, Marc, Beasley, Richard, Ebeling, Peter R., Ferguson, Murdo, Nissen, Michael D., Rheault, Paul, Simpson, Richard W., De Ridder, Marc, Crasta, Priya D., Miller, Jacqueline M. and Trofa, Andrew F. (2016). Prospective clinical trial of hepatitis B vaccination in adults with and without type-2 diabetes mellitus. Human Vaccines and Immunotherapeutics, 12 (8), 2197-2203. doi: 10.1080/21645515.2016.1164362
2015
Journal Article
Immune responses to a recombinant, four-component, meningococcal serogroup B vaccine (4CMenB) in adolescents: A phase III, randomized, multicentre, lot-to-lot consistency study
Perrett, Kirsten P., McVernon, Jodie, Richmond, Peter C., Marshall, Helen, Nissen, Michael, August, Allison, Percell, Sandra, Toneatto, Daniela and Nolan, Terry (2015). Immune responses to a recombinant, four-component, meningococcal serogroup B vaccine (4CMenB) in adolescents: A phase III, randomized, multicentre, lot-to-lot consistency study. Vaccine, 33 (39), 5217-5224. doi: 10.1016/j.vaccine.2015.06.103
2015
Journal Article
Specific rolling circle amplification of low-copy human polyomaviruses BKV, HPyV6, HPyV7, TSPyV, and STLPyV
Rockett, Rebecca, Barraclough K.A., Isbel, Nicole M., Dudley, Kevin J., Nissen, Michael D., Sloots, Theo P. and Bialasiewicz, Seweryn (2015). Specific rolling circle amplification of low-copy human polyomaviruses BKV, HPyV6, HPyV7, TSPyV, and STLPyV. Journal of Virological Methods, 215-216, 17-21. doi: 10.1016/j.jviromet.2015.02.004
2015
Journal Article
Deep sequence characterisation of a divergent HPIV-4a from an adult with prolonged influenza-like illness
Arden, Katherine E., Beatson, Scott A., Lambert, Stephen B., Wang, Claire W. T., McVernon, Jodie, Nissen, Michael D., Nolan, Terry, Sloots, Theo P. and Mackay, Ian M. (2015). Deep sequence characterisation of a divergent HPIV-4a from an adult with prolonged influenza-like illness. Virology Reports, 5, 19-28. doi: 10.1016/j.virep.2015.02.001
2015
Journal Article
Acquisition of human polyomaviruses in the first 18 months of life
Rockett, Rebecca J., Bialasiewicz, Seweryn, Mhango, Lebogang, Gaydon, Jane, Holding, Rebecca, Whiley, David M., Lambert, Stephen B., Ware, Robert S., Nissen, Michael D., Grimwood, Keith and Sloots, Theo P. (2015). Acquisition of human polyomaviruses in the first 18 months of life. Emerging Infectious Diseases, 21 (2), 365-367. doi: 10.3201/eid2102.141429
2014
Journal Article
Enhancing influenza diagnostics to catch a shifting target
Whiley, David M., Mackay, Ian M., Nimmo, Graeme R., Sloots, Theo P. and Nissen, Michael D. (2014). Enhancing influenza diagnostics to catch a shifting target. Lancet Infectious Diseases, 14 (10), 923-923. doi: 10.1016/S1473-3099(14)70916-8
2014
Journal Article
High-throughput informative single nucleotide polymorphism-based typing of Neisseria gonorrhoeae using the Sequenom MassARRAY iPLEX platform
Trembizki, Ella, Smith, Helen, Lahra, Monica M., Chen, Marcus, Donovan, Basil, Fairley, Christopher K., Guy, Rebecca, Kaldor, John, Regan, David, Ward, James, Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2014). High-throughput informative single nucleotide polymorphism-based typing of Neisseria gonorrhoeae using the Sequenom MassARRAY iPLEX platform. Journal of Antimicrobial Chemotherapy, 69 (6), 1526-1532. doi: 10.1093/jac/dkt544
2014
Journal Article
Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing
Bialasiewicz, Seweryn, McVernon, Jodie, Nolan, Terry, Lambert, Stephen B., Zhao, Guoyan, Wang, David, Nissen, Michael D. and Sloots, Theo P. (2014). Detection of a divergent Parainfluenza 4 virus in an adult patient with influenza like illness using next-generation sequencing. BMC Infectious Diseases, 14 (1) 275, 275.1-275.5. doi: 10.1186/1471-2334-14-275
2014
Journal Article
A comparison of two informative SNP-based strategies for typing Pseudomonas aeruginosa isolates from patients with cystic fibrosis
Syrmis, Melanie W., Kidd, Timothy J., Moser, Ralf J., Ramsay, Kay A., Gibson, Kristen M., Anuj, Snehal, Bell, Scott C., Wainwright, Claire E., Grimwood, Keith, Nissen, Michael, Sloots, Theo P. and Whiley, David M. (2014). A comparison of two informative SNP-based strategies for typing Pseudomonas aeruginosa isolates from patients with cystic fibrosis. BMC Infectious Diseases, 14 (1) 307, 307.1-307.8. doi: 10.1186/1471-2334-14-307
2014
Journal Article
Epidemiology of respiratory viral infections in children enrolled in a study of influenza vaccine effectiveness
Dierig, Alexa, Heron, Leon G., Lambert, Stephen B., Yin, Jiehui Kevin, Leask, Julie, Chow, Maria Yui Kwan, Sloots, Theo P., Nissen, Michael D., Ridda, Iman and Booy, Robert (2014). Epidemiology of respiratory viral infections in children enrolled in a study of influenza vaccine effectiveness. Influenza and other Respiratory Viruses, 8 (3), 293-301. doi: 10.1111/irv.12229
2014
Journal Article
Potential Animal and Environmental Sources of Q Fever Infection for Humans in Queensland
Tozer, S.J., Lambert, S.B., Strong, C.L., Field, H.E., Sloots, T.P. and Nissen, M.D. (2014). Potential Animal and Environmental Sources of Q Fever Infection for Humans in Queensland. Zoonoses and Public Health, 61 (2), 105-112. doi: 10.1111/zph.12051
2014
Journal Article
Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control
Alsaleh, Asma N., Whiley, David M., Bialasiewicz, Seweryn, Lambert, Stephen B., Ware, Robert S., Nissen, Michael D., Sloots, Theo P. and Grimwood, Keith (2014). Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control. BMC Infectious Diseases, 14 (1) 15, 15. doi: 10.1186/1471-2334-14-15
2014
Journal Article
Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance
Goire, Namraj, Lahra, Monica M., Chen, Marcus, Donovan, Basil, Fairley, Christopher K., Guy, Rebecca, Kaldor, John, Regan, David, Ward, James, Nissen, Michael D., Sloots, Theo P. and Whiley, David M. (2014). Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance. Nature Reviews Microbiology, 12 (3), 223-229. doi: 10.1038/nrmicro3217
2014
Journal Article
Screening for H7N9 influenza A by matrix gene-based real-time reverse-transcription PCR
Hackett, H., Bialasiewicz, S., Jacob, K., Bletchly, C., Harrower, B., Nimmo, G.R., Nissen, M.D., Sloots, T.P. and Whiley, D.M. (2014). Screening for H7N9 influenza A by matrix gene-based real-time reverse-transcription PCR. Journal of Virological Methods, 195, 123-125. doi: 10.1016/j.jviromet.2013.10.016
2014
Journal Article
PCR to diagnose infectious disease
Sloots, T.P. and Nissen, M.D. (2014). PCR to diagnose infectious disease. European Pharmaceutical Review, 19 (3), 68-74.
2014
Journal Article
A national quality assurance survey of Neisseria gonorrhoeae testing
Trembizki, E., Lahra, M., Stevens, K., Freeman, K., Hogan, T., Hogg, G., Lawrence, A., Limnios, A., Pearson, J., Smith, H., Nissen, M., Sloots, T. and Whiley, D.M. (2014). A national quality assurance survey of Neisseria gonorrhoeae testing. Journal of Medical Microbiology, 63 (PART 1), 45-49. doi: 10.1099/jmm.0.065094-0
2014
Journal Article
Immunogenicity and safety of a CRM-conjugated meningococcal ACWY vaccine administered concomitantly with routine vaccines starting at 2 months of age
Nolan, T.M., Nissen, M.D., Naz, A., Shepard, J., Bedell, L., Hohenboken, M., Odrljin, T. and Dull, P.M. (2014). Immunogenicity and safety of a CRM-conjugated meningococcal ACWY vaccine administered concomitantly with routine vaccines starting at 2 months of age. Human Vaccines and Immunotherapeutics, 10 (2), 280-289. doi: 10.4161/hv.27051
2013
Journal Article
High-throughput molecular typing of microbes using the Sequenom Massarray platform
Whiley, David, Trembizki, Ella, Syrmis, Melanie, Nakos, Jenny, Bletchly, Cheryl, Nissen, Michael, Nimmo, Graeme and Sloots, Theo P. (2013). High-throughput molecular typing of microbes using the Sequenom Massarray platform. Microbiology Australia, 34 (4), 175-177. doi: 10.1071/MA13058
2013
Journal Article
Safety and tolerability of a 2009 trivalent inactivated split-virion influenza vaccine in infants, children and adolescents
Lambert, Stephen B., Chuk, Lai-man R., Nissen, Michael D., Nolan, Terry M., McVernon, Jodie, Booy, Robert, Heron, Leon, Richmond, Peter C., Walls, Tony, Marshall, Helen S., Reynolds, Graham J., Hartel, Gunter F., Hu, Wilson and Lai, Michael H. (2013). Safety and tolerability of a 2009 trivalent inactivated split-virion influenza vaccine in infants, children and adolescents. Influenza and other Respiratory Viruses, 7 (5), 676-685. doi: 10.1111/irv.12107
2013
Journal Article
Bordetella holmesii and pertussis diagnosis: authors' reply
Cox, Hannah C., Jacob, Kevin, Whiley, David M., Bletchly, Cheryl, Nimmo, Graeme R., Nissen, Michael D. and Sloots, Theo P. (2013). Bordetella holmesii and pertussis diagnosis: authors' reply. Pathology, 45 (5), 532-532. doi: 10.1097/PAT.0b013e3283639c0d
Funding
Supervision
Availability
- Dr Michael Nissen is:
- Available for supervision
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Supervision history
Completed supervision
-
2013
Doctor Philosophy
Molecular Characterisation and Detection of Gonococcal Antimicrobial Resistance.
Principal Advisor
Other advisors: Associate Professor David Whiley
-
2010
Doctor Philosophy
Clinical and virological characteristics of human metapneumovirus
Principal Advisor
-
2005
Doctor Philosophy
RESPIRATORY DISEASES IN PATIENTS WITH CYSTIC FIBROSIS: ROLE AND PATHOGENESIS OF PSEUDOMONAS AERUGINOSA INFECTION
Principal Advisor
-
2003
Doctor Philosophy
REAL-TIME DETECTION, DIFFERENTIATION AND QUANTITATION OF CLINICALLY RELEVANT VIRUSES
Principal Advisor
-
2010
Doctor Philosophy
Characterisation of Newly Discovered Human Polyomaviruses WU and KI
Joint Principal Advisor
-
2016
Doctor Philosophy
A nationwide study of Neisseria gonorrhoeae antimicrobial resistance; towards molecular AMR surveillance
Associate Advisor
Other advisors: Associate Professor David Whiley
-
2015
Doctor Philosophy
Epidemiology, Diagnosis and Prevention of Q fever in Queensland.
Associate Advisor
-
2015
Doctor Philosophy
Characterising the Pathogenesis and Biology of Newly Described Human Polyomaviruses
Associate Advisor
Other advisors: Associate Professor David Whiley, Dr Seweryn Bialasiewicz
-
2013
Doctor Philosophy
Detection, Identification and Genotyping of Pseudomonas aeruginosa strains isolated from environmental and clinical samples.
Associate Advisor
Other advisors: Associate Professor David Whiley
-
2011
Doctor Philosophy
Ribozymes as Antivirals for Respiratory Syncytial Virus
Associate Advisor
Other advisors: Professor Paul Young
-
2008
Doctor Philosophy
Factors Affecting Nucleic Acid Amplification Tests for Neisseria Gonorrhoeae
Associate Advisor
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