Dr Michael Nissen
Dr

Michael Nissen

Email: 

Background

Michael has over 30 years’ experience in clinical medicine (infectious diseases & paediatrics) and clinical laboratory microbiology with a particular interest in the epidemiology of vaccine preventable diseases and the diagnosis of infectious diseases in hospital, public health and industry settings. He recently took up the inaugural Director of Research at The Prince Charles Hospital in Brisbane.

He is a past Principal Medical Officer and Director of CoVID-19 Pharmacovigilance at the Therapeutic Goods Administration, Department of Health & Ageing, Australian Government (2021-2022), Director of Scientific Affairs & Public Health for GSK Vaccines in the Greater China Intercontinental region based in Singapore (2014-2020) and Director of Infectious Diseases at the Royal Children’s Hospital-Brisbane and a practising Clinical Microbiologist at the Royal Brisbane & Women’s Hospitals (2000-2014). Michael is a past full member of the Australian Technical Advisory Group for Immunisation from 2007 to 2013.

Prof. Nissen has 223 peer-reviewed medical publications and book chapters, a h- index of 64 with 13,321 citations of his work to date. His research interests include the epidemiology and prevention of vaccine preventable diseases and the rapid molecular diagnostic techniques of infectious diseases.

Availability

Dr Michael Nissen is:
Available for supervision

Fields of research

Clinical sciences Medical microbiology

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia

Research impacts

Founder & Co-Lead of Queensland Paediatric Infectious Diseases Laboratory & Associate Professor, University of Queensland Australia: 2003-2014

Research laboratory dedicated to viral discovery, translational adaption of molecular techniques for the diagnosis of infectious and rapid molecular diagnosis of respiratory viruses. Co-discoverer of WU virus. Lead approximately 40 Phase I-IV vaccine trials in attached clinical trials unit including meningococcal and staphylococcal candidates. Established experience in the maintenance and utility of large microbiology (virus and bacteria) and serum biobanks that lead to significant viral discoveries and clinical translation.

Co-discoverer of WU Virus: 2007

Gaynor AM, MD Nissen, DM Whiley, IM Mackay, SB Lambert, G Wu, DC Brennan, GA Storch, TP Sloots, D Wang (2007). Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathogens May 4; 3(5):e64 doi:10.1371/journal.ppat.0030064 (Citations: 846).

Director of Infectious Diseases, Royal Children’s Hospital-Brisbane, QLD AUSTRALIA: 2003-2014

Foundation and Inaugural Director of Clinical Infectious Diseases (Infection Management Prevention Service-IMPS) and Pre-Eminent Staff Specialist at largest children’s hospital in Queensland and State-based Children’s Health Service (CHS). Established Antimicrobial Stewardship (AMS) Committee at CHS and developed the “AntibioCard.” Also acted as Chair of the Infection Control Committee during this period and served as paediatric representative on State Health Medicines Advisory Committee (2000-2014).

Search Professor Michael Nissen’s works on UQ eSpace

201 works between 1984 and 2023
All (201) Journal Article (176) Book Chapter (5) Conference Publication (18) Other Outputs (2)

161 - 180 of 201 works

2006

Journal Article

Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

Arden, Katherine E., McErlean, Peter, Nissen, Michael D, Sloots, Theo P. and Mackay, Ian M. (2006). Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. Journal of Medical Virology, 78 (9), 1232-1240. doi: 10.1002/jmv.20689

Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

2006

Conference Publication

Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection

Sloots, T. P., McErlean, P., Speicher D. J., Arden, K., Nissen, M. D. and Mackay, I.M. (2006). Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Australia, 2006.

Evidence of human coronavirus NL63, HKU1 and human bocavirus in Australian children with acute respiratory infection

2006

Conference Publication

Factors influencing the sensitivity of the malarial PCR assay.

Bialasiewicz S., Whiley D., Nissen, M. D. and Sloots, T. P. (2006). Factors influencing the sensitivity of the malarial PCR assay.. ASM SVM Special Interest Group Meeting, Brisbane, 2006.

Factors influencing the sensitivity of the malarial PCR assay.

2006

Journal Article

Evidence of human coronavirus HKU1 and human bocavirus in Australian children

Sloots, Theo P., McErlean, Peter, Speicher, David J., Arden, Katherine E., Nissen, Michael D. and Mackay, Ian M. (2006). Evidence of human coronavirus HKU1 and human bocavirus in Australian children. Journal of Clinical Virology, 35 (1), 99-102. doi: 10.1016/j.jcv.2005.09.008

Evidence of human coronavirus HKU1 and human bocavirus in Australian children

2006

Conference Publication

A newly identified human rhinovirus present in young children with bronchiolitis

McErlean P., Shackelton L., Nissen, M. D., Sloots, T. P. and Mackay, Ian M. (2006). A newly identified human rhinovirus present in young children with bronchiolitis. IX International Symposium on Respiratory Viral Infections, Causeway Bay, Hong Kong, 3-6 March 2007.

A newly identified human rhinovirus present in young children with bronchiolitis

2005

Journal Article

New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia

Arden, Katherine E., Nissen, Michael D., Sloots, Theo P. and Mackay, Ian M. (2005). New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia. Journal Of Medical Virology, 75 (3), 455-462. doi: 10.1002/jmv.20288

New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia

2005

Conference Publication

Detection of an integron associated aadb-resistance gene in Pseudomonas aeruginosa isolates from patients with CF

Syrmis, M., O'Carroll, M., Iredell, J., Wainwright, C. E., Coulter, C., Sloots, T., Bell, S. C. and Nissen, M. (2005). Detection of an integron associated aadb-resistance gene in Pseudomonas aeruginosa isolates from patients with CF. 28th European Cystic Fibrosis Conference, Crete, Greece, 22-25 Jun, 2005. Amsterdam, Netherlands: Elsevier BV.

Detection of an integron associated aadb-resistance gene in Pseudomonas aeruginosa isolates from patients with CF

2005

Journal Article

Method for detection of respiratory viruses in the sputa of patients with cystic fibrosis

Punch, G., Syrmis, M. W., Rose, B. R., Harbour, C., Bye, P. T. P., Nissen, M. D., Elkins, M. R. and Sloots, T. P. (2005). Method for detection of respiratory viruses in the sputa of patients with cystic fibrosis. European Journal of Clinical Microbiology & Infectious Diseases, 24 (1), 54-57. doi: 10.1007/s10096-004-1273-7

Method for detection of respiratory viruses in the sputa of patients with cystic fibrosis

2005

Journal Article

Disseminated Scedosporium prolificans infection and survival of a child with acute lymphoblastic leukemia

Whyte, Morag, Irving, Helen, ORegan, Peter, Nissen, Michael, Siebert, David and LaBrom, Robert (2005). Disseminated Scedosporium prolificans infection and survival of a child with acute lymphoblastic leukemia. Pediatric Infectious Disease Journal, 24 (2), 375-377. doi: 10.1097/01.inf.0000157213.94392.30

Disseminated Scedosporium prolificans infection and survival of a child with acute lymphoblastic leukemia

2005

Conference Publication

Detection of an integron associated aadB resistance gene in Pseudomonas aeruginosa isolates from patients with CF

Syrmis, M., O'Carroll, M., Iredell, J., Wainwright, C., Coulter, C., Sloots, T., Bell, S. and Nissen, M. (2005). Detection of an integron associated aadB resistance gene in Pseudomonas aeruginosa isolates from patients with CF. 2005 Annual Scientific Meeting The Thoracic Society of Australia and New Zealand, Perth, Australia, 18-23 March, 2005. Carlton South, Victoria: Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2005.00663.x-i1

Detection of an integron associated aadB resistance gene in Pseudomonas aeruginosa isolates from patients with CF

2005

Conference Publication

Upper respiratory illness aetiology and symptomatology in elite and recreationally competitive athletes

Spence, L., Nissen, M. D., Sloots, T. P., McCormack, J. G., Locke, S., Pyne, D. B., Fricker, P. A. and Brown, W. J. (2005). Upper respiratory illness aetiology and symptomatology in elite and recreationally competitive athletes. 7th ISEI Symposium, Monte Carlo, 15-17 September, 2005. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/j.bbi.2005.06.001

Upper respiratory illness aetiology and symptomatology in elite and recreationally competitive athletes

2005

Journal Article

Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults

Kitchener, S., Nissen, M. D., Nasveld, P., Forrat, R., Yoksan, S., Lang, J. and Saluzzo, J. (2005). Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults. Vaccine, 1238-1241. doi: 10.1016/j.vaccine.2005.09.029

Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults

2004

Journal Article

Use of the P gene to genotype human metapneumovirus identifies 4 viral subtypes

Mackay, Ian M., Bialasiewiecz, Seweryn, Waliuzzaman, Zubair, Chidlow, Glenys R., Fegredo, David C., Laingam, Somprasong, Adamson, Penny, Harnett, Gerald B., Rawlinson, William, Nissen, Michael D. and Sloots, Theo P. (2004). Use of the P gene to genotype human metapneumovirus identifies 4 viral subtypes. Journal of Infectious Diseases, 190 (11), 1913-1918. doi: 10.1086/425013

Use of the P gene to genotype human metapneumovirus identifies 4 viral subtypes

2004

Journal Article

Pertussis vaccination for new parents?

McCall, B. J., Davison, R. P., Nissen, M. D. and Nourse, C. B. (2004). Pertussis vaccination for new parents?. Medical Journal of Australia, 181 (10), 578-578. doi: 10.5694/j.1326-5377.2004.tb06456.x

Pertussis vaccination for new parents?

2004

Journal Article

Rapid genotyping of Pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based PCR assays

Syrmis, Melanie W., O'Carroll, Mark R., Sloots, Theo P., Coulter, Chris, Wainwright, Claire E., Bell, Scott C. and Nissen, Michael D. (2004). Rapid genotyping of Pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based PCR assays. Journal of Medical Microbiology, 53 (11), 1089-1096. doi: 10.1099/jmm.0.45611-0

Rapid genotyping of Pseudomonas aeruginosa isolates harboured by adult and paediatric patients with cystic fibrosis using repetitive-element-based PCR assays

2004

Journal Article

Clonal strains of Pseudomonas aeruginosa in paediatric and adult cystic fibrosis units

O'Carroll, M. R., Syrmis, M. W., Wainwright, C. E., Greer, R. M., Mitchell, P., Coulter, C., Sloots, T. P., Nissen, M. D. and Bell, S. C. (2004). Clonal strains of Pseudomonas aeruginosa in paediatric and adult cystic fibrosis units. European Respiratory Journal, 24 (1), 101-106. doi: 10.1183/09031936.04.00122903

Clonal strains of Pseudomonas aeruginosa in paediatric and adult cystic fibrosis units

2004

Journal Article

Detection and differentiation of Plasmodium species by polymerase chain reaction and colorimetric detection in blood samples of patients with suspected malaria

Whiley, David M., LeCornec, Genevera M., Baddeley, Annette, Savill, John, Syrmis, Melanie W., Mackay, Ian M., Siebert, David J., Burns, Dominic, Nissen, Michael and Sloots, Theo P. (2004). Detection and differentiation of Plasmodium species by polymerase chain reaction and colorimetric detection in blood samples of patients with suspected malaria. Diagnostic Microbiology And Infectious Disease, 49 (1), 25-29. doi: 10.1016/j.diagmicrobio.2003.10.014

Detection and differentiation of Plasmodium species by polymerase chain reaction and colorimetric detection in blood samples of patients with suspected malaria

2004

Journal Article

A sensitive, specific, and cost-effective multiplex reverse transcriptase-PCR assay for the detection of seven common respiratory viruses in respiratory samples

Syrmis, Melanie W., Whiley, David M., Thomas, Marion, Mackay, Ian M., Williamson, Jeanette, Siebert, David J., Nissen, Michael D. and Sloots, Theo P. (2004). A sensitive, specific, and cost-effective multiplex reverse transcriptase-PCR assay for the detection of seven common respiratory viruses in respiratory samples. Journal of Molecular Diagnostics, 6 (2), 125-131. doi: 10.1016/S1525-1578(10)60500-4

A sensitive, specific, and cost-effective multiplex reverse transcriptase-PCR assay for the detection of seven common respiratory viruses in respiratory samples

2004

Book Chapter

Human Metapenumovirus: Paramyxoviridae

Nissen, M. D. (2004). Human Metapenumovirus: Paramyxoviridae. Textbook of Pediatric Infectious Diseases. (pp. 2341-2346) edited by Ralph D. Feigin, Gail J. Demmler, James D. Cherry and Sheldon L. Kaplan. Philadelphia, Pa.: Saunders.

Human Metapenumovirus: Paramyxoviridae

2004

Conference Publication

Identifying the aetiology of upper respiratory illness in elite and recreational athletes

Spence, L., Nissen, M. D., Sloots, T. P., McCormack, J. G., Locke, S., Pyne, D., Fricker, P. and Brown, W. J. (2004). Identifying the aetiology of upper respiratory illness in elite and recreational athletes. Hot Topics from the Red Centre, Alice Springs, NT, Australia, 6-9 October 2004. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/S1440-2440(04)80138-5

Identifying the aetiology of upper respiratory illness in elite and recreational athletes

Past funding

  • 2013 - 2016
    Q fever: How common is it and how can we best prevent it? Research to inform Q fever vaccine policy in Australia and Internationally. (NHMRC project grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2010 - 2016
    Molecular microbiology and epidemiology of respiratory infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2010 - 2011
    Development of a novel assay for the detection of clonal P.aeruginosa in persons with CF
    Australian Cystic Fibrosis Research Trust
    Open grant
  • 2010 - 2014
    Burden of respiratory infection in the first 2 years of life: a birth cohort study of emerging respiratory pathogens
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Characterisation of novel picornavirus-like viruses identified from patients with acute respiratory infections
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    Clinical impact of clonal Pseudomonas aeruginosa in cystic fibrosis
    NHMRC Project Grant
    Open grant
  • 2007 - 2010
    The clinical and epidemiological characterisation of a newly discovered human polyonmavirus, WU (WU Virus Research)
    Royal Children's Hospital Foundation
    Open grant
  • 2006
    Identification of Virulence Markers in the Respiratory Syncytial Virus Genome
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2006
    Characterisation and Epidemiology of Emerging Pathogens in Paediatrics
    ANZ Executors and Trustees' Company Ltd
    Open grant
  • 2005 - 2010
    Research support for paediatric infectious diseases
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    Epidemiology and Control of Q Fever in Children
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2010
    How Children and adults with cystic fibrosis get lung infections with Pseudomonas aeruginosa
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2010
    (i) Detection of mucoid P. aeruginosa antigens and antibodies in CF (ii) Molecular epidemiology of respiratory syncytial virus infections and the immune response in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2003
    Macquarie Bank Asthma Research Fellowship for 2003
    Royal Australasian College of Physicians
    Open grant
  • 2003 - 2008
    The clinical significance of human metapneumovirus infections in Australian children
    Royal Children's Hospital Foundation
    Open grant
  • 2002
    Molecular epidemiology of respiratory syncitial virus in Australia
    UQ Early Career Researcher
    Open grant
  • 2001
    Establishment of a Malarial & Molecular Research Program at the RCH, Brisbane
    Royal Children's Hospital Foundation
    Open grant
  • 2001
    Real-time diagnosis of respiratory tract infections in children
    Royal Children's Hospital Foundation
    Open grant
  • 2000 - 2001
    Establishment of a Paediatric and Molecular Infectious Diseases Research Program at the Royal Children's Hospital, Brisbane
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2000
    Competitive Research Equipment Grant
    Royal Children's Hospital Foundation
    Open grant

Availability

Dr Michael Nissen is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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