Associate Professor Dominic Ng
Associate Professor

Dominic Ng

Email: 
Phone: 
+61 7 336 53077

Background

Dr Dominic Ng graduated with a BSc (Hons) and gained his PhD from the University of Western Australia. His doctoral studies, conducted in the laboratory of Assoc. Prof. Marie Bogoyevitch, were focused on cardiomyocyte signalling mechanisms regulating pathological tissue growth (ie cardiac hypertrophy). He continued his research training in Singapore as a post-doctoral research fellow based at the Institute of Molecular and Cell Biology, the flagship institute of Singapore’s science agency (A*STAR) located at the world renowned Biopolis research precinct. During this time, his research interests turned to the complex regulation of the cytoskeleton and their functions in development and disease.

He returned to the Australian medical research community on an NHMRC Peter Doherty Fellowship (2006-2010) followed by a Faculty Trust Roper Fellowship (2011-2012). In this time, Dominic established an independent research program focused on complex signalling regulation of microtubule organization. In 2013, Dominic was appointed as a Senior Research Fellow, supported by an ARC Future Fellowship (2013-2016) at the Department of Biochemistry within the Bio21 Institute, University of Melbourne. In 2015, Dominic relocated his research group to the School of Biomedical Science, University of Queensland and is currently appointed as an ARC Future Fellow and Senior Lecturer.

Availability

Associate Professor Dominic Ng is:
Available for supervision

Fields of research

Biological Sciences Biomedical and Clinical Sciences Cardiovascular medicine and haematology Cardiovascular medicine and haematology not elsewhere classified Cell development, proliferation and death Neurosciences Oncology and carcinogenesis Signal transduction

Qualifications

  • Bachelor of Science, University of Western Australia
  • Doctor of Philosophy, University of Western Australia

Research interests

  • Cell Signalling

    Protein phosphorylation, protein interactions, kinases, STAT transcription factors, microtubule-associated proteins.

  • Molecular Cardiology

    Cardiomyocyte growth, cardiac hypertrophy, cardiac injury, cardioprotection

  • Neural Development

    Neural stem cells, microcephaly genes, neural migration, neural proliferation, neuronal cell death

Search Professor Dominic Ng’s works on UQ eSpace

69 works between 2000 and 2024
All (69) Journal Article (68) Book Chapter (1)

61 - 69 of 69 works

2006

Journal Article

Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

Ng, Dominic Chi Hiung, Lin, Bao Hong, Lim, Cheh Peng, Huang, Guochang, Zhang, Tong, Poli, Valerie and Cao, Xinmin (2006). Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. Journal of Cell Biology, 172 (2), 245-257. doi: 10.1083/jcb.200503021

Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin

2005

Journal Article

Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology

Grounds, Haslett R., Ng, Dominic C. H. and Bogoyevitch, Marie A. (2005). Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology. Journal of Cellular Biochemistry, 95 (3), 529-542. doi: 10.1002/jcb.20441

Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology

2004

Journal Article

GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I

Huang, Guochang, Lu, Hao, Hao, Aijun, Ng, Dominic C. H., Ponniah, Sathivel, Guo, Ke, Lufei, Chengchen, Zeng, Qi and Cao, Xinmin (2004). GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Molecular and Cellular Biology, 24 (19), 8447-8456. doi: 10.1128/MCB.24.19.8447-8456.2004

GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I

2003

Journal Article

Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts

Ng, Dominic C.H., Court, Naomi W., Dos Remedios, Cristobal G. and Bogoyevitch, Marie A. (2003). Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts. Cardiovascular Research, 57 (2), 333-346. doi: 10.1016/S0008-6363(02)00664-8

Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts

2002

Journal Article

Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery

Bogoyevitch, Marie A., Kendrick, Tulene S., Ng, Dominic C.H. and Barr, Renae K. (2002). Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery. DNA and Cell Biology, 21 (12), 879-894. doi: 10.1089/104454902762053846

Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery

2001

Journal Article

Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid

Bogojevitch, Marie A., Thien, Marilyn and Ng, Dominic C. H. (2001). Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid. Journal of Biochemistry and Molecular Biology, 34 (6), 517-525.

Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid

2001

Journal Article

A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology

Ng, Dominic C. H., Long, Carlin S. and Bogoyevitch, Marie A. (2001). A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology. Journal of Biological Chemistry, 276 (31), 29490-29498. doi: 10.1074/jbc.M100699200

A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology

2000

Journal Article

The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3

Ng, Dominic C. H. and Bogoyevitch, Marie A. (2000). The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3. Journal of Biological Chemistry, 275 (52), 40856-40866. doi: 10.1074/jbc.M004639200

The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3

2000

Journal Article

Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes

Bogoyevitch, Marie A., Ng, Dominic C.H., Court, Naomi W., Draper, Karen A., Dhillon, Amardeep and Abas, Lindy (2000). Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 32 (8), 1469-1480. doi: 10.1006/jmcc.2000.1187

Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes

Current funding

  • 2025 - 2026
    Striking a sour note: Revealing ageing-related intracellular acidification as a trigger for ALS pathomechanisms
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2023 - 2025
    Understanding how the ALS risk factor, GGNBP2, contributes to autophagy
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant

Past funding

  • 2019
    Advanced Brightfield and Fluorescent High Speed and Throughput Slide Scanner for biological, medical, materials science, and agricultural applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2022
    How defects in centrosome to microtubule attachment cause microcephaly
    NHMRC Project Grant
    Open grant
  • 2019 - 2023
    Identifying conserved alternative splicing mechanisms in vivo
    NHMRC Project Grant
    Open grant
  • 2017 - 2021
    Trophoblast cell-cell fusion in preeclampsia
    NHMRC Project Grant
    Open grant
  • 2016 - 2018
    Mitotic spindle regulation by novel Aurora A control mechanisms [The Robert Baillie Research Grant]
    Cancer Council Queensland
    Open grant
  • 2015 - 2016
    Interrogating a novel protein scaffold that coordinates signal transduction and molecular motor function
    ARC Future Fellowships
    Open grant
  • 2015 - 2016
    New insights into mechanisms that coordinate kinase signalling and molecular motors in mitosis: A novel role for the protein scaffold WD-repeat protein 62 (WDR62)
    NHMRC Project Grant
    Open grant

Availability

Associate Professor Dominic Ng is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Characterising a new role for the microcephaly protein WDR62 in cellular purine metabolism

    Principal Advisor

    Other advisors: Associate Professor Sean Millard

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Professor Wally Thomas, Dr Melissa Reichelt

  • Doctor Philosophy

    Tuning mitophagy in mitochondrial disease

    Associate Advisor

    Other advisors: Dr Julia Pagan

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Professor Wally Thomas, Dr Melissa Reichelt

Completed supervision

Enquiries

For media enquiries about Associate Professor Dominic Ng's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au