Overview
Background
I am an Associate Professor in the School of Biomedical Sciences (SBMS) at The University of Queensland, where I teach physiology and lead research that explores how cells respond to stress, injury and disease. My work aims to better understand the molecular and cellular processes that influence health and disease, with a particular focus on areas relevant to cancer, heart disease, neurological conditions and emerging cell-based therapies.
I completed my doctorate at the University of Western Australia in Biochemistry and Cell Biology, where I studied how heart cells respond to signals that can drive abnormal tissue growth. I then undertook postdoctoral training in Singapore at the Institute of Molecular and Cell Biology, part of A*STAR, where my research expanded into understanding how the cytoskeleton, internal structures of cells, help control development and disease.
After returning to Australia, I was supported by national fellowships from the NHMRC and ARC, which enabled me to establish an internationally connected research program. My research brings together cell biology, imaging, computational approaches and emerging technologies to uncover how cells make critical decisions, including whether to survive or die under stress.
Alongside my research and teaching, I contribute to leadership within SBMS as Director of Research and support major research infrastructure initiatives across the Faculty of Health, Medicine and Behavioural Sciences (HMBS) as Academic Director of Research Infrastructure. I also serve on steering committees for UQ’s Viral Vector Core (VVC) and the Centre for Cardiovascular Health and Research (CCVHR), helping to strengthen the platforms and partnerships that support biomedical discovery and translation.
Availability
- Associate Professor Dominic Ng is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, University of Western Australia
- Doctor of Philosophy, University of Western Australia
Research interests
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Cell Signalling
Protein phosphorylation, protein interactions, kinases, STAT transcription factors, microtubule-associated proteins.
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Molecular Cardiology
Cardiomyocyte growth, cardiac hypertrophy, cardiac injury, cardioprotection
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Neural Development
Neural stem cells, microcephaly genes, neural migration, neural proliferation, neuronal cell death
Research impacts
My research contributes to society by improving understanding of how cells respond to stress, injury and disease, generating knowledge that can inform new approaches to diagnosis, prevention and treatment. By uncovering the molecular mechanisms that influence cell survival, tissue growth and disease progression, my work supports advances in areas of major health burden, including cancer, cardiovascular disease and neurological conditions. Beyond academic discovery, this research helps strengthen Australia’s biomedical innovation pipeline by supporting translational partnerships, enabling platform technologies such as viral vectors and advanced imaging, and training the next generation of researchers with skills relevant to the health, biotechnology and medical research sectors.
Works
Search Professor Dominic Ng’s works on UQ eSpace
2008
Journal Article
Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition
Ng, Dominic C. H., Gebski, Bijanka L., Grounds, Miranda D. and Bogoyevitch, Marie A. (2008). Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition. Cell Motility and the Cytoskeleton, 65 (1), 40-58. doi: 10.1002/cm.20242
2006
Journal Article
Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin
Ng, Dominic Chi Hiung, Lin, Bao Hong, Lim, Cheh Peng, Huang, Guochang, Zhang, Tong, Poli, Valerie and Cao, Xinmin (2006). Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. Journal of Cell Biology, 172 (2), 245-257. doi: 10.1083/jcb.200503021
2005
Journal Article
Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology
Grounds, Haslett R., Ng, Dominic C. H. and Bogoyevitch, Marie A. (2005). Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology. Journal of Cellular Biochemistry, 95 (3), 529-542. doi: 10.1002/jcb.20441
2004
Journal Article
GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I
Huang, Guochang, Lu, Hao, Hao, Aijun, Ng, Dominic C. H., Ponniah, Sathivel, Guo, Ke, Lufei, Chengchen, Zeng, Qi and Cao, Xinmin (2004). GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Molecular and Cellular Biology, 24 (19), 8447-8456. doi: 10.1128/MCB.24.19.8447-8456.2004
2003
Journal Article
Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts
Ng, Dominic C.H., Court, Naomi W., Dos Remedios, Cristobal G. and Bogoyevitch, Marie A. (2003). Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts. Cardiovascular Research, 57 (2), 333-346. doi: 10.1016/S0008-6363(02)00664-8
2002
Journal Article
Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery
Bogoyevitch, Marie A., Kendrick, Tulene S., Ng, Dominic C.H. and Barr, Renae K. (2002). Taking the cell by stealth or storm? Protein Transduction Domains (PTDs) as versatile vectors for delivery. DNA and Cell Biology, 21 (12), 879-894. doi: 10.1089/104454902762053846
2001
Journal Article
Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid
Bogojevitch, Marie A., Thien, Marilyn and Ng, Dominic C. H. (2001). Characterization of Protein Kinases Activated during Treatment of Cells with Okadaic Acid. Journal of Biochemistry and Molecular Biology, 34 (6), 517-525.
2001
Journal Article
A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology
Ng, Dominic C. H., Long, Carlin S. and Bogoyevitch, Marie A. (2001). A Role for the Extracellular Signal-regulated Kinase and p38 Mitogen-activated Protein Kinases in Interleukin-1β-stimulated Delayed Signal Tranducer and Activator of Transcription 3 Activation, Atrial Natriuretic Factor Expression, and Cardiac Myocyte Morphology. Journal of Biological Chemistry, 276 (31), 29490-29498. doi: 10.1074/jbc.M100699200
2000
Journal Article
The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3
Ng, Dominic C. H. and Bogoyevitch, Marie A. (2000). The mechanism of heat shock activation of ERK mitogen-activated protein kinases in the interleukin 3-dependent proB cell line BaF3. Journal of Biological Chemistry, 275 (52), 40856-40866. doi: 10.1074/jbc.M004639200
2000
Journal Article
Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes
Bogoyevitch, Marie A., Ng, Dominic C.H., Court, Naomi W., Draper, Karen A., Dhillon, Amardeep and Abas, Lindy (2000). Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 32 (8), 1469-1480. doi: 10.1006/jmcc.2000.1187
Funding
Current funding
Supervision
Availability
- Associate Professor Dominic Ng is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Tuning mitophagy in mitochondrial disease
Associate Advisor
Other advisors: Associate Professor Julia Pagan
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Doctor Philosophy
Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.
Associate Advisor
Other advisors: Professor Wally Thomas, Dr Melissa Reichelt
Completed supervision
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2026
Doctor Philosophy
A novel role for the microcephaly protein WDR62 in protein folding and purine metabolism
Principal Advisor
Other advisors: Associate Professor Sean Millard
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2024
Doctor Philosophy
Optogenetic control of cell signalling dynamics and stress responses
Principal Advisor
Other advisors: Associate Professor Sean Millard
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2020
Doctor Philosophy
Characterization of the microcephaly gene wd40-repeat protein 62 (wdr62) in brain growth and development
Principal Advisor
Other advisors: Associate Professor Sean Millard
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2024
Doctor Philosophy
Characterising the role of Dscam2 in synaptic vesicle recycling and memory formation in Drosophila.
Associate Advisor
Other advisors: Associate Professor Sean Millard
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2024
Doctor Philosophy
Defining the function of SCF-FBXO16 ubiquitin ligase at centrosomes and microtubules
Associate Advisor
Other advisors: Associate Professor Samantha Stehbens, Associate Professor Julia Pagan
Media
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