Dr Fekade Sime
Dr

Fekade Sime

Email: 
Phone: 
+61 7 334 65023

Availability

Dr Fekade Sime is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of South Australia

Search Professor Fekade Sime’s works on UQ eSpace

87 works between 2012 and 2024
All (87) Journal Article (78) Book Chapter (3) Conference Publication (6)

81 - 87 of 87 works

2015

Journal Article

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 (8) dkv123, 2369-2375. doi: 10.1093/jac/dkv123

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

2015

Conference Publication

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

Sime, F. B., Roberts, M., Tiong, I. S., Gardner, J., Lehman, S., Peake, S., Hahn, U., Warner, M. and Roberts, J. (2015). Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial. 20th Congress of European Hematology Association, Vienna, Austria, 11-14 June 2015. Pavia, Italy: Fondazione Ferrata Storti.

Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial

2014

Journal Article

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014). How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 (288) 288, 1-11. doi: 10.1186/1471-2334-14-288

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

2014

Journal Article

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

2014

Journal Article

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

2014

Journal Article

Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy

Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 (6), 3533-3537. doi: 10.1128/AAC.02340-14

Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy

2012

Journal Article

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35

Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review

Current funding

  • 2021 - 2025
    Optimizing outpatient parenteral antibiotic therapy to support hospital-in-the-home program across the unique environmental conditions of Australia
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2023
    Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU Study
    Gilead Australia Fellowship
    Open grant
  • 2022 - 2023
    Evaluation of the stability of ceftazidime-avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy-A regulatory compliance study in accordance with the requireme
    Pfizer Inc Global Medical Grant
    Open grant
  • 2022 - 2023
    Evaluation of the stability of Aciclovir in elastomeric infusion devices used for Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2021
    Evaluation of the stability of Aciclovir in elastomeric infusion devises used in Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2021 - 2022
    Evaluation of the stability of Amoxicillin in elastomeric infusion devices used for Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2019 - 2021
    Screening anti-fungal exposure in intensive care unit
    European Society of Clinical Microbiology and Infectious Diseases Study Group Research Grant
    Open grant
  • 2019
    Preventing bacterial biofilm formation in dialysis and advanced oxygenation therapy machines through optimized dosing of antibiotics
    UQ Early Career Researcher
    Open grant
  • 2016 - 2019
    A translational approach to optimisation of antimicrobial therapy for critically ill patients that prevents the emergence of 'superbugs'
    UQ Fellowships
    Open grant

Availability

Dr Fekade Sime is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy

    Principal Advisor

    Other advisors: Professor Jason Roberts

  • Doctor Philosophy

    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)

    Principal Advisor

    Other advisors: Professor Jason Roberts

  • Doctor Philosophy

    Barriers and facilitators of the implementation and expansion of outpatient parenteral antimicrobial therapy program

    Principal Advisor

  • Doctor Philosophy

    Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models

    Principal Advisor

    Other advisors: Professor Jason Roberts

  • Doctor Philosophy

    In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams

    Principal Advisor

    Other advisors: Professor Jason Roberts

  • Doctor Philosophy

    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)

    Associate Advisor

    Other advisors: Professor Jason Roberts

  • Doctor Philosophy

    Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.

    Associate Advisor

    Other advisors: Dr Suzanne Parker, Professor Jason Roberts

Completed supervision

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